LCN1基因详情-基因数据库-基因云馆

LCN1(lipocalin 1) 转至新版数据库

基因简称(symbol)

LCN1 [HGNC] [GeneCards] [NCBI]

基因种类(locus group)

protein-coding gene

同源简称(alias symbol)

VEGP|TP|PMFA|MGC71975|TLC

基因家族代码(gene_family_id)

631 [HGNC] [GenScript]

omim代码

151675

entrez码

3933 [Vega]

vega基因码

OTTHUMG00000020908

ensembl基因码

ENSG00000160349 [Ensembl]

基因家族(gene family)

Lipocalins

refseq数据库代号

NM_002297

更多...

基因种类(locus_type)

gene with protein product

基因名称状态(status)

Approved

location_sortable

09q34

同源基因名称(alias name)

Von Ebner gland protein|tear lipocalin|lipocalin 1-like 2|tear prealbumin

基因名称批准使用时间(date_approved_reserved)

1993-05-03T00:00:00Z

基因简称更名时间(date_symbol_changed)

基因名称更名时间(date_name_changed)

2011-11-01T00:00:00Z

更新时间(date_modified)

2014-11-19T00:00:00Z

ucsc码

uc022bpk.1

ena

ccds数据码

CCDS6991

uniprot数据码

P31025

pubmed代码

8276406

mgd码

rgd码

RGD:619872

生命科学数据库(lsdb)

更新时间(date modified)

2014-11-19T00:00:00Z

cosmic

LCN1

mirbase

基因曾用简称(prev symbol)

基因曾用名称(prev name)

lipocalin 1 (protein migrating faster than albumin, tear prealbumin)|lipocalin 1 (tear prealbumin)

homeodb

cosmic

LCN1

snornabase

bioparadigms slc

orphanet

假基因信息(pseudogeneorg)

horde id

merops

imgt

iuphar

kznf基因类别

mamit-trnadb

cd

LncRNA数据库

酶代码

中间纤维数据库

收起

9q34

This gene encodes a member of the lipocalin family of small secretory proteins. Lipocalins are extracellular transport proteins that bind to a variety of hydrophobic ligands. The encoded protein is the primary lipid binding protein in tears and is overproduced in response to multiple stimuli including infection and stress. The encoded protein may be a marker for chromosome aneuploidy as well as an autoantigen in Sjogren's syndrome. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and two pseudogenes of this gene are also located on the long arm of chromosome 9. [provided by RefSeq, Nov 2011]

[中文简述(自动翻译):] 该基因编码的脂笼蛋白家族的小分泌蛋白的一个成员。脂质运载蛋白是结合到各种疏水性配体的胞外转运蛋白。所编码的蛋白质是主要的脂质流泪结合蛋白，是响应于多种刺激，包括感染和应力过量产生。所编码的蛋白质可以是用于染色体非整倍性的标志物，以及在干燥综合征的自身抗原。另外剪接转录变体编码多种亚型已经观察到这种基因，而这种基因的两个假也位于[由RefSeq的，2011年11月提供的]的9号染色体长臂

OMIM数据库中对LCN1基因的介绍 Wikipedia数据库中对LCN1基因的介绍

LCN1基因的碱基序列：[NCBI]

LCN1基因的碱基突变：显示全部snp

rs210088 rs2120943 rs3216169 rs3827832 rs4841993 rs11103047 rs11103048 rs11103049 rs12379612 rs13284515 rs34042004 rs34145173 rs35905708 rs55678722 rs55713520 rs55773005 rs55775231 rs55790166 rs55884352 rs56024916 rs56120410 rs56239374 rs57441942 rs58661479 rs58879611 rs59238865 rs60636792 rs60961679 rs61214391 rs61306308 rs61570826 rs61735422 rs72766516 rs73560954 rs73560965 rs73560977 rs73666342

rs73666345 rs73666346 rs74418328 rs74561543 rs74688417 rs74776898 rs75042515 rs75138074 rs75426811 rs75682638 rs76057225 rs76105585 rs76300417 rs76650634 rs76684552 rs77171640 rs77441762 rs78130575 rs78218434 rs78488179 rs78618688 rs78639978 rs78694875 rs78741921 rs79262643 rs79428809 rs80167272 rs80337519 rs111385730 rs111506900 rs111589804 rs111794576 rs111836055 rs111841855 rs112090657 rs112377568 rs112487993 rs112672543 rs112777878 rs112959046 rs112999544 rs113353120 rs113368614 rs113491743 rs113519500 rs113630740 rs113643267 rs113844284 rs113978830 rs114050065 rs114093070 rs114168448 rs114870340 rs115665996 rs115921344 rs115924039 rs116365993 rs116397263 rs116703314 rs116795992 rs116993711 rs117058757 rs117161567 rs117638349 rs117747534 rs117814227 rs137969977 rs138180278 rs138245590 rs138667519 rs139335104 rs139342578 rs139386147 rs139540399 rs140311484 rs140888175 rs141009496 rs141014325 rs141110652 rs141225321 rs141302773 rs141543465 rs141659926 rs141824251 rs142098402 rs143234130 rs143259160 rs143276070 rs143345996 rs143361927 rs143501807 rs143570737 rs143608580 rs144161694 rs144683645 rs144808389 rs145263717 rs145767506 rs146192526 rs146328087 rs146476619 rs146799231 rs147081757 rs147117257 rs147908440 rs147941714 rs148132972 rs148215832 rs148534030 rs148751420 rs149241966 rs149258569 rs149613064 rs149629560 rs150315597 rs150536266 rs150717851 rs151184622 rs180862035 rs181188857 rs181650065 rs181906090 rs182530194 rs183113850 rs183378402 rs183805846 rs184170490 rs184277878 rs185619395 rs186465820 rs187188994 rs187256761 rs187515008 rs187584931 rs187999684 rs188890815 rs189044198 rs189652297 rs191112175 rs191919023 rs192623723 rs193057580 rs199573452 rs199895720 rs199966911 rs200175305 rs200368052 rs200448006 rs200530565 rs200773811 rs200824516 rs201058632 rs201216628 rs201258758 rs201351780 rs201625070 rs201677579 rs201868744 rs201928228 rs201982610 rs202095766 rs202145925 rs367725856 rs367826767 rs367859507 rs367936646 rs368388221 rs368794703 rs368799976 rs368953450 rs369346571 rs369513064 rs369599589 rs369783977 rs369805485 rs369814066 rs370139207 rs370267016 rs370706633 rs371082125 rs371163348 rs371208614 rs371365986 rs371576149 rs372034741 rs372091204 rs372311702 rs372337144 rs372487263 rs372970561 rs373103672 rs373116403 rs373239623 rs373587388 rs373844915 rs374415872 rs374430782 rs374493645 rs374525019 rs374610782 rs374951723 rs375850738 rs376213510 rs376583599 rs376943318 rs377067577 rs377120035 rs377244175 rs377426880 rs377445147 rs377529267 rs377721700 rs397840196 rs527347336 rs527353837 rs527718855 rs527909887 rs528315185 rs528679273 rs529589375 rs529632731 rs530116227 rs530307741 rs530339848 rs530376753 rs530611578 rs530717951 rs530755345 rs530990434 rs531602314 rs532745950 rs533177988 rs533425200 rs534196117 rs534304125 rs534470561 rs534545826 rs534599917 rs534641649 rs534657332 rs534681146 rs534886215 rs534921913 rs535302668 rs535427092 rs536304010 rs536680513 rs536904190 rs537244711 rs537245688 rs537346647 rs538653734 rs539318180 rs539646289 rs540095896 rs540472169 rs541067228 rs541137383 rs541327454 rs541370646 rs541695751 rs541728434 rs541820582 rs541956450 rs543076568 rs543123345 rs543678933 rs543727734 rs544027587 rs544078262 rs544119671 rs544545582 rs544867188 rs545130585 rs545383625 rs545463441 rs545518631 rs545561308 rs545826641 rs546079542 rs546591563 rs546830515 rs547261919 rs547427997 rs547499354 rs547665596 rs547830553 rs547865238 rs548214826 rs548878631 rs548879365 rs549856842 rs550938524 rs551507348 rs551562929 rs551600135 rs551869354 rs551872805 rs552229718 rs552242962 rs552379763 rs552851558 rs552960496 rs553063254 rs553106680 rs553451507 rs553638803 rs554029836 rs554267652 rs554736301 rs554955123 rs555089513 rs555498516 rs555897511 rs556034479 rs557038893 rs557349098 rs557566053 rs557613631 rs559831930 rs561028450 rs561032208 rs561395036 rs561507468 rs562147967 rs562674837 rs562691300 rs562799577 rs563077176 rs563471795 rs563631174 rs563809550 rs564242783 rs564837276 rs565068096 rs565183669 rs565708587 rs565831700 rs565875558 rs566136825 rs566730741 rs566868103 rs567474192 rs567535201 rs567609335 rs567609373 rs568651053 rs568799874 rs569254689 rs569488569 rs569613970 rs569760466 rs569941778 rs569981479 rs570654835 rs570657566 rs570834731 rs571193018 rs571891267 rs572031755 rs572980480 rs573281802 rs573304692 rs573421494 rs573696976 rs573875499 rs573904715 rs574083911 rs574094421 rs574273699 rs574343041 rs574346876 rs575337486 rs575567758 rs575764610 rs576002655 rs576047351 rs576243686 rs576535367 rs576953212 rs577716831 rs578230161 rs745381039 rs745689334 rs745878751 rs745986447 rs746251906 rs746487391 rs746542386 rs746758540 rs746841584 rs747010685 rs747036156 rs747453759 rs747593153 rs747633235 rs747662917 rs747891338 rs748161433 rs748274038 rs748524292 rs748720902 rs749004316 rs749032743 rs749340456 rs749390772 rs749815492 rs749908793 rs750192268 rs750703568 rs750820450 rs751317734 rs751593446 rs751605187 rs751834808 rs752496340 rs752683525 rs752734741 rs752784473 rs753237624 rs753587334 rs753928978 rs754608924 rs754807646 rs755106174 rs755135331 rs755364188 rs755617276 rs755896031 rs755955757 rs755986065 rs756346324 rs756827021 rs757094899 rs757148316 rs757172272 rs757675797 rs757801303 rs758030394 rs758169679 rs758218859 rs758549135 rs758758972 rs758813914 rs759035027 rs759044260 rs759362777 rs759400777 rs759401763 rs760010896 rs760177009 rs760513644 rs760545402 rs761108746 rs761179314 rs761404518 rs761857621 rs761908779 rs761914767 rs762156818 rs762485484 rs762734972 rs762798075 rs763012297 rs764017490 rs764221109 rs764304003 rs764481964 rs764556368 rs764795539 rs764956367 rs765109723 rs765296041 rs765579199 rs766115848 rs766310107 rs766676556 rs766729585 rs767424769 rs767608466 rs767639665 rs767870617 rs767990438 rs768078622 rs768137205 rs768195622 rs768245070 rs768298509 rs768409319 rs768672080 rs768895070 rs769451785 rs769628368 rs770029647 rs770110598 rs770460196 rs770618542 rs770681104 rs770691280 rs770975457 rs771477955 rs771524451 rs771579585 rs772047539 rs772057424 rs772084504 rs772137550 rs772285152 rs772665508 rs772824339 rs772985139 rs773229161 rs773312165 rs773788130 rs773894931 rs774082899 rs774415104 rs774466869 rs774968677 rs774988763 rs775525907 rs775573055 rs775627944 rs775780826 rs775862817 rs776394912 rs776397582 rs776482774 rs777008068 rs777087402 rs777140743 rs777281933 rs777322058 rs777361834 rs777558840 rs777796421 rs777829454 rs778407818 rs778421020 rs778426809 rs778631804 rs779071186 rs779427557 rs779663052 rs780444789 rs780455251 rs780584853 rs781224936 rs781474202 rs781504134 rs781592940

LCN1基因在不同组织中的表达： [UniProt]

正向引物序列

正向引物Tm值

反向引物序列

反向引物Tm值

rank

GATTCAGGATGTGTCAGGG

57

ACCGATTCCAGATTCATCTC

57

GAGATTCAGGATGTGTCAGG

57

CGATTCCAGATTCATCTCAGG

58

AGATTCAGGATGTGTCAGGG

59

CCGATTCCAGATTCATCTCAG

58

尚未收录相关数据

LCN1基因（以及对应的蛋白质）的细胞分布位置：

[UniProt] [GenomeNet]

溶酶体
内涵体
细胞核
细胞质
液泡
细胞膜
细胞外基质
内质网
线粒体
高尔基体
细胞骨架

LCN1基因的本体（GO）信息：

GO库代码

对应的蛋白质

来源代码

GO:0001895

P31025(UniProtKB)

IEP

GO:0004869

P31025(UniProtKB)

TAS

GO:0005576

P31025(UniProtKB)

TAS

GO:0005615

P31025(UniProtKB)

IDA

GO:0005615

P31025(UniProtKB)

IDA

GO:0006508

P31025(UniProtKB)

TAS

GO:0010951

P31025(UniProtKB)

IEA

GO:0015909

P31025(UniProtKB)

TAS

GO:0050896

P31025(UniProtKB)

IEA

GO:0050909

P31025(UniProtKB)

IEA

GO:0070062

P31025(UniProtKB)

IDA

序号	作用方式	资源库来源/分值	基因名称	基因名称

可能调控LCN1基因的相关microRNA：

hsa-miR-335

通路基因列表

疾病名称

关系值

NofPmids

NofSnps

来源

疾病名称	关系值	NofPmids	NofSnps	来源
Sjogren's Syndrome	0.00272435	1	0	LHGDN
Alzheimer's Disease	0.002367032	1	0	GAD
Bronchiolitis Obliterans	0.000271442	1	0	BeFree
Carcinoma, Transitional Cell	0.000271442	1	0	BeFree
Exanthema	0.000271442	1	0	BeFree
Mycoses	0.000271442	1	0	BeFree
Teratocarcinoma	0.000271442	1	0	BeFree
Carcinoma breast stage IV	0.000271442	1	0	BeFree
invasive cancer	0.000271442	1	0	BeFree
Spots on skin	0.000271442	1	0	BeFree