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Dendritic cells (DCs) are the most potent antigen-presenting cells. Immature DCs efficiently capture antigens and differentiate into interdigitating dendritic cells (IDCs) in lymphoid tissues that induce primary T-cell responses (summary by de Saint-Vis et al., 1998 [PubMed 9768752]).[supplied by OMIM, Dec 2010]
[中文简述(自动翻译):]  树突状细胞(DC)是最有效的抗原呈递细胞。未成熟DC有效地捕捉抗原和分化成相互交叉在淋巴组织树突细胞器(IDC),该诱导初级T细胞应答(通过圣 - 可见。等,1998年概要[搜索PubMed 9768752])。[由OMIM,2010年12月供给]
LAMP3基因(以及对应的蛋白质)的细胞分布位置:
LAMP3基因的本体(GO)信息:
疾病名称 | 关系值 | NofPmids | NofSnps | 来源 |
Bipolar Disorder | 0.129468128 | 4 | 2 | GAD_GWASCAT |
Influenza | 0.121900093 | 8 | 0 | BeFree_CTD_human |
Rheumatoid Arthritis | 0.002995792 | 2 | 0 | BeFree_LHGDN |
Adenocarcinoma | 0.00272435 | 1 | 0 | LHGDN |
melanoma | 0.00272435 | 1 | 0 | LHGDN |
Parkinson Disease | 0.002638474 | 2 | 1 | BeFree_GAD |
HIV Infections | 0.002171535 | 8 | 0 | BeFree |
Neoplasm Metastasis | 0.001628651 | 6 | 0 | BeFree |
Dengue Fever | 0.001357209 | 5 | 0 | BeFree |
Virus Diseases | 0.001085767 | 4 | 0 | BeFree |
Tuberculosis | 0.000814326 | 3 | 0 | BeFree |
Respiratory syncytial virus (RSV) infection in conditions classified elsewhere and of unspecified site | 0.000814326 | 3 | 0 | BeFree |
Malignant neoplasm of breast | 0.000542884 | 2 | 0 | BeFree |
Chikungunya Fever | 0.000542884 | 2 | 0 | BeFree |
Japanese Encephalitis | 0.000542884 | 2 | 0 | BeFree |
Malaria | 0.000542884 | 2 | 0 | BeFree |
Rabies (disorder) | 0.000542884 | 2 | 0 | BeFree |
Rubella | 0.000542884 | 2 | 0 | BeFree |
Breast Carcinoma | 0.000542884 | 2 | 0 | BeFree |
Severe Acute Respiratory Syndrome | 0.000542884 | 2 | 0 | BeFree |
Malignant tumor of cervix | 0.000271442 | 1 | 0 | BeFree |
Uterine Cervical Neoplasm | 0.000271442 | 1 | 0 | BeFree |
Coxsackievirus Infections | 0.000271442 | 1 | 0 | BeFree |
Gastroenteritis | 0.000271442 | 1 | 0 | BeFree |
IGA Glomerulonephritis | 0.000271442 | 1 | 0 | BeFree |
Hemorrhagic Fevers, Viral | 0.000271442 | 1 | 0 | BeFree |
Leishmaniasis, Cutaneous | 0.000271442 | 1 | 0 | BeFree |
Malignant neoplasm of stomach | 0.000271442 | 1 | 0 | BeFree |
African Trypanosomiasis | 0.000271442 | 1 | 0 | BeFree |
Tuberculosis, Pulmonary | 0.000271442 | 1 | 0 | BeFree |
Adenocarcinoma of lung (disorder) | 0.000271442 | 1 | 0 | BeFree |
Tumor Progression | 0.000271442 | 1 | 0 | BeFree |
Heart Failure, Right-Sided | 0.000271442 | 1 | 0 | BeFree |
Mucolipidosis Type IV | 0.000271442 | 1 | 0 | BeFree |
Cervix carcinoma | 0.000271442 | 1 | 0 | BeFree |
Stomach Carcinoma | 0.000271442 | 1 | 0 | BeFree |
Glycogen Storage Disease Type IIb | 0.000271442 | 1 | 0 | BeFree |
Sialic Acid Storage Disease, Finnish Type (disorder) | 0.000271442 | 1 | 0 | BeFree |
Mammary Neoplasms | 0.000271442 | 1 | 0 | BeFree |
Colorectal Cancer | 0.000271442 | 1 | 0 | BeFree |
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