KRT13(keratin 13, type I)

基因基本信息

基因基本信息

基因简称(symbol)
    [HGNC]     [GeneCards]     [NCBI]
基因种类(locus group)
同源简称(alias symbol)
基因家族代码(gene_family_id)
    [HGNC]     [GenScript]
omim代码
entrez码
    [Vega]
vega基因码
ensembl基因码
    [Ensembl]
基因家族(gene family)
refseq数据库代号

更多...

基因种类(locus_type)
基因名称状态(status)
location_sortable
同源基因名称(alias name)
基因名称批准使用时间(date_approved_reserved)
基因简称更名时间(date_symbol_changed)
基因名称更名时间(date_name_changed)
更新时间(date_modified)
ucsc码
ena
ccds数据码
uniprot数据码
pubmed代码
mgd码
rgd码
生命科学数据库(lsdb)
更新时间(date modified)
cosmic
mirbase
基因曾用简称(prev symbol)
基因曾用名称(prev name)
homeodb
cosmic
snornabase
bioparadigms slc
orphanet
假基因信息(pseudogeneorg)
horde id
merops
imgt
iuphar
kznf基因类别
mamit-trnadb
cd
LncRNA数据库
酶代码
中间纤维数据库

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基因染色体位置

基因染色体位置

17q21.2
基因染色体位置图

基因简述

基因简述

The protein encoded by this gene is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. This type I cytokeratin is paired with keratin 4 and expressed in the suprabasal layers of non-cornified stratified epithelia. Mutations in this gene and keratin 4 have been associated with the autosomal dominant disorder White Sponge Nevus. The type I cytokeratins are clustered in a region of chromosome 17q21.2. Alternative splicing of this gene results in multiple transcript variants; however, not all variants have been described. [provided by RefSeq, Jul 2008]

[中文简述(自动翻译):]  由该基因编码的蛋白质是角蛋白基因家族的一个成员。所述角蛋白是负责上皮细胞的结构完整性中间丝蛋白和被细分为细胞角蛋白和头发角蛋白。大多数类型的我角蛋白由被布置成对异型角蛋白链的酸性蛋白质。这种类型的我角蛋白配对与角蛋白4和非角质化分层上皮的基底层层表达。在此基因和角蛋白4突变与常染色体显性紊乱白色海绵痣相关联。 I型角蛋白聚集在染色体17q21.2的区域。在多个转录变异体本基因的结果的选择性剪接;然而，并非所有的变体已有描述。 [由RefSeq的，2008年7月提供]

OMIM数据库中对KRT13基因的介绍     Wikipedia数据库中对KRT13基因的介绍

基因序列

基因序列

KRT13基因的碱基序列：[NCBI]

基因突变

基因突变

KRT13基因的碱基突变：           显示全部snp
rs903       rs1031       rs736932       rs760134       rs1001378       rs3169911       rs4796697       rs4796698       rs7211835       rs8074539       rs8076366       rs8079823       rs8081495       rs8081580       rs8182306       rs9891361       rs9908874       rs9915981       rs9916359       rs11550071       rs11653148       rs11868816       rs12150581       rs12603751       rs34047520       rs34367942       rs60923621       rs61092365       rs61126695       rs71373416       rs71373417       rs72832099       rs73986307       rs76221682       rs76318578       rs77644022       rs77815497      
rs77879418       rs78223890       rs79104752       rs79846820       rs80099814       rs80114041       rs111307652       rs111375341       rs111611424       rs112485608       rs112679639       rs113465968       rs113547405       rs114369311       rs114757055       rs114809434       rs115100417       rs115159720       rs115460515       rs115535218       rs115695615       rs117151355       rs117463992       rs117927937       rs118111321       rs138102206       rs138885186       rs138959511       rs139279979       rs139318123       rs139724008       rs139794439       rs140015179       rs140142101       rs140157860       rs140342847       rs140772266       rs140780704       rs140888301       rs141310122       rs141374521       rs141432690       rs141462482       rs141526550       rs141882539       rs141918873       rs142006859       rs142183272       rs142246675       rs142526332       rs142856552       rs142895125       rs143070715       rs143664622       rs144144601       rs144382056       rs144891464       rs144967807       rs145000563       rs145116138       rs145167376       rs145318131       rs145983286       rs146161354       rs146289936       rs146666963       rs146891290       rs146918776       rs147005767       rs147022064       rs147564962       rs147822928       rs147825336       rs147841491       rs148102980       rs148150964       rs148296285       rs148399399       rs148521008       rs148672161       rs149040043       rs149077503       rs149623369       rs149866915       rs150020980       rs150321809       rs150650575       rs150845230       rs150899638       rs150947773       rs151159779       rs181122697       rs182065519       rs182471030       rs183340971       rs184209365       rs184288644       rs184849301       rs185787290       rs186978211       rs187147482       rs187207967       rs187448324       rs187577438       rs188347004       rs188713834       rs189154771       rs189224137       rs189918547       rs190113786       rs190634556       rs191151809       rs191381347       rs192084256       rs192772396       rs199505704       rs199533132       rs199762312       rs199933871       rs200269035       rs200297080       rs200309164       rs200359046       rs200529637       rs200615971       rs200839212       rs201006488       rs201273553       rs201356802       rs201435685       rs201545698       rs201712135       rs201949656       rs202015813       rs202025008       rs202057977       rs202106893       rs202173288       rs267607388       rs367591767       rs367712050       rs367953709       rs368051143       rs368494222       rs368888147       rs368939384       rs369135048       rs369163489       rs369742463       rs370135273       rs370715601       rs371297226       rs371567219       rs371850724       rs373085505       rs373159660       rs373485747       rs374219463       rs374240623       rs374452685       rs375023751       rs375082810       rs375666790       rs375724051       rs375760692       rs376484003       rs376949316       rs377002499       rs377025441       rs527414871       rs528276062       rs528337261       rs528472413       rs529091319       rs529660795       rs529905353       rs530276850       rs530296574       rs530596803       rs530902322       rs530989393       rs531211732       rs532767746       rs532984019       rs533023584       rs533155581       rs534033835       rs534245943       rs534528851       rs535020030       rs535169722       rs536018954       rs536098358       rs536111111       rs536709984       rs538092958       rs538303362       rs538782344       rs538888673       rs538986969       rs539059100       rs539705083       rs539707550       rs540098551       rs540148736       rs540538607       rs540737274       rs540960561       rs541385960       rs542468782       rs542552368       rs544249807       rs544323078       rs544534078       rs545038474       rs545122148       rs545219692       rs545778118       rs546085808       rs546456289       rs546669568       rs546706173       rs546880172       rs547662398       rs547998854       rs548070268       rs548989486       rs549128472       rs550693344       rs551329482       rs551367433       rs551770914       rs552137773       rs552325168       rs552657836       rs552715693       rs553607074       rs554102680       rs554243979       rs554292565       rs554915056       rs555359627       rs555576958       rs555645864       rs555746824       rs556283373       rs556542745       rs557436178       rs557734635       rs558089092       rs558277294       rs558432006       rs558493667       rs559349765       rs559834758       rs560232648       rs560509278       rs561692703       rs561825064       rs562062740       rs562135978       rs562188557       rs562500897       rs562630541       rs562693749       rs563890731       rs564020618       rs564582965       rs565217320       rs565278598       rs566270961       rs566296163       rs566477295       rs567753244       rs567980915       rs568162948       rs568270612       rs569014208       rs569531004       rs570479666       rs570689594       rs571743989       rs572348007       rs572360111       rs572415903       rs573954696       rs574184263       rs575001981       rs575329571       rs575902934       rs575915751       rs576765311       rs577900764       rs577914800       rs577951959       rs745658844       rs745756968       rs745768178       rs745938353       rs746055814       rs746117318       rs746141279       rs746248658       rs746421136       rs746536640       rs746574569       rs746606962       rs746696292       rs746913289       rs746998705       rs747067918       rs747084203       rs747217763       rs747249003       rs747286637       rs747428896       rs747710702       rs747752896       rs747849871       rs748028479       rs748231018       rs748299083       rs748425210       rs748511951       rs748583604       rs748603563       rs748803289       rs748805338       rs748841601       rs748999503       rs749009134       rs749334030       rs749450779       rs749461317       rs749496713       rs749593745       rs749787699       rs749838803       rs749916295       rs749972851       rs750023619       rs750061864       rs750110704       rs750169491       rs750215998       rs750503082       rs750665992       rs750793720       rs750811980       rs750900235       rs750991125       rs750997449       rs751003803       rs751046381       rs751138953       rs751156638       rs751242837       rs751353143       rs751384562       rs751617162       rs751809395       rs752150478       rs752191840       rs752390503       rs752625754       rs752701638       rs752715620       rs752740050       rs752806435       rs752831701       rs752935985       rs753084306       rs753182982       rs753272265       rs753462261       rs753468933       rs753746189       rs753767170       rs753888719       rs753925971       rs753928241       rs754220281       rs754310122       rs754317054       rs754430921       rs754525340       rs754723592       rs754732492       rs754948802       rs754996481       rs755226206       rs755356463       rs755412445       rs755604664       rs755706974       rs755872173       rs755910617       rs756052301       rs756069072       rs756140635       rs756153506       rs756336768       rs756355811       rs756532133       rs756654902       rs756740779       rs756870891       rs756886209       rs756970882       rs757012196       rs757023592       rs757172151       rs757454086       rs757460197       rs757491325       rs757683192       rs757762718       rs757809964       rs757861009       rs757967563       rs758084444       rs758378900       rs758386353       rs758476417       rs758486017       rs758585565       rs758595204       rs758815327       rs758902395       rs758993002       rs759150262       rs759178223       rs759227258       rs759421487       rs759429187       rs759481994       rs759629819       rs759824069       rs760061507       rs760111749       rs760305890       rs760502700       rs760565338       rs760566540       rs760772792       rs761201809       rs761493307       rs761496103       rs761510147       rs761613318       rs761659747       rs761699251       rs761941717       rs762086095       rs762141883       rs762270993       rs762358997       rs762541345       rs762655823       rs762660600       rs762735104       rs762855075       rs762855901       rs763056747       rs763295293       rs763544433       rs763546425       rs763708756       rs763742361       rs763785395       rs764004897       rs764088068       rs764706490       rs764768768       rs764975817       rs765076132       rs765163933       rs765210698       rs765346427       rs765454386       rs765660876       rs765717279       rs765844638       rs765959217       rs766029088       rs766054115       rs766141128       rs766421222       rs766421806       rs766482425       rs766700666       rs766787967       rs766875731       rs766894151       rs766948707       rs767038726       rs767150938       rs767234570       rs767264822       rs767411003       rs767440923       rs767542845       rs767618537       rs767777473       rs767943356       rs768193818       rs768394880       rs768459234       rs768484775       rs768524188       rs768649405       rs768722370       rs768812171       rs768904310       rs768940664       rs769371388       rs769557851       rs769594376       rs769783171       rs769874748       rs770086272       rs770113117       rs770118226       rs770281794       rs770292730       rs770647667       rs770790139       rs771074447       rs771164488       rs771244979       rs771357034       rs771435962       rs771722010       rs771980528       rs772208892       rs772226938       rs772368091       rs772668908       rs772857124       rs772942425       rs773034808       rs773120305       rs773405109       rs773577944       rs773686071       rs773710186       rs773776343       rs773889691       rs773962135       rs773983288       rs774022235       rs774083465       rs774263110       rs774457214       rs774483710       rs775287167       rs775403847       rs775411186       rs775420729       rs775491837       rs775542127       rs775614888       rs775707361       rs776182292       rs776357918       rs776360373       rs776447589       rs776554416       rs777034991       rs777038018       rs777105329       rs777117907       rs777408013       rs777493765       rs777516978       rs777603079       rs777605109       rs777839874       rs777961602       rs777972648       rs778111036       rs778149661       rs778165896       rs778305209       rs778359491       rs778562268       rs778645444       rs779098221       rs779187731       rs779293187       rs779527087       rs779663494       rs779753347       rs779798862       rs779846006       rs779856764       rs779863868       rs780154003       rs780601116       rs780698429       rs780811887       rs780820686       rs780908590       rs781005051       rs781012520       rs781291691       rs781372161       rs781460268       rs781460720       rs781478241       rs781728994      

基因表达

基因表达

KRT13基因在不同组织中的表达：    [UniProt]

基因在不同组织中的表达图

基因引物

基因引物

正向引物序列
正向引物Tm值
反向引物序列
反向引物Tm值
rank
GGACATCAAGACACGTCTG
58
AAACCAATCATCTTGGCGTC
59
TGGTTCCACACCAAGAGTG
60
TGATCTCTGTCTTGCTGGTC
60
CTCCTCACTTTACAGAAGAGC
58
GGTCAGGATCTCTAAACTGTC
58
GGACATCAAGACACGTCTG
58
AAACCAATCATCTTGGCGTC
59
CTATGGAGGTGGTTTCGGG
60
CATGGTGATCGAGTTGAACAG
59
TCCTCACTTTACAGAAGAGC
57
GGTCAGGATCTCTAAACTGTC
58
GACATCAAGACACGTCTGG
58
GAAACCAATCATCTTGGCG
57
AAATGATAAGCCGAGGCAC
58
GTAACAGAGGTGCTACGGG
60
AGCTATGGAGGTGGTTTCG
60
GTTCTGCATGGTGATCGAG
59
TGGTTCCACACCAAGAGTG
60
GTGATCTCTGTCTTGCTGGT
60

转录因子

转录因子

      尚未收录相关数据

基因本体信息

KRT13基因（以及对应的蛋白质）的细胞分布位置：

[UniProt]     [GenomeNet]

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • 溶酶体
  • 内涵体
  • 细胞核
  • 细胞质
  • 液泡
  • 细胞膜
  • 细胞外基质
  • 内质网
  • 线粒体
  • 高尔基体
  • 细胞骨架

KRT13基因的本体（GO）信息：

GO库代码
对应的蛋白质
来源代码
GO:0005198
K7EMD9(UniProtKB)
IEA
GO:0005882
K7EMD9(UniProtKB)
IEA
GO:0005198
K7EQH6(UniProtKB)
IEA
GO:0005882
K7EQH6(UniProtKB)
IEA
GO:0045111
K7EQH6(UniProtKB)
IDA
GO:0005198
K7ERE3(UniProtKB)
IEA
GO:0005882
K7ERE3(UniProtKB)
IEA
GO:0045111
K7ERE3(UniProtKB)
IDA
GO:0005198
P13646(UniProtKB)
IEA
GO:0005634
P13646(UniProtKB)
IDA
GO:0007010
P13646(UniProtKB)
IDA
GO:0009314
P13646(UniProtKB)
IEA
GO:0043587
P13646(UniProtKB)
IEA
GO:0045095
P13646(UniProtKB)
IDA
GO:0045111
P13646(UniProtKB)
IDA
GO:0045111
P13646(UniProtKB)
IDA
GO:0070062
P13646(UniProtKB)
IDA
GO:0070062
P13646(UniProtKB)
IDA
GO:0070062
P13646(UniProtKB)
IDA
GO:0071300
P13646(UniProtKB)
IEA

基因相互作用关系

基因相互作用关系

基因与其他基因之间的相互作用关系图
序号 作用方式 资源库来源/分值 基因名称 基因名称

基因相关microRNA

基因相关microRNA

可能调控KRT13基因的相关microRNA：     

基因通路图

基因通路图

基因的通路属性图
通路基因列表

基因相关疾病

基因相关疾病

疾病名称 关系值 NofPmids NofSnps 来源
疾病名称 关系值 NofPmids NofSnps 来源
Leukokeratosis, Hereditary Mucosal 0.121900093 7 0 BeFree_CTD_human
Squamous cell carcinoma of esophagus 0.120271442 2 0 BeFree_CTD_human
WHITE SPONGE NEVUS 2 0.12 4 0 UNIPROT
Adenocarcinoma 0.00272435 1 0 LHGDN
Squamous cell carcinoma 0.001085767 4 0 BeFree
Malignant neoplasm of mouth 0.000542884 2 0 BeFree
Lip and Oral Cavity Carcinoma 0.000542884 2 0 BeFree
Malignant neoplasm of breast 0.000271442 1 0 BeFree
Leukoplakia 0.000271442 1 0 BeFree
Mixed Salivary Gland Tumor 0.000271442 1 0 BeFree
Neoplasm Metastasis 0.000271442 1 0 BeFree
Oral Cavity Carcinoma 0.000271442 1 0 BeFree
Adenocarcinoma Of Esophagus 0.000271442 1 0 BeFree
Carcinogenesis 0.000271442 1 0 BeFree
CARCINOMA OF VULVA 0.000271442 1 0 BeFree
Breast Carcinoma 0.000271442 1 0 BeFree

基因相关文献

基因相关文献

基因相关服务

基因相关服务

基因评论

基因评论

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