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This gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region. [provided by RefSeq, Jul 2008]
[中文简述(自动翻译):]  本基因,姬ras癌基因来自哺乳动物ras基因家族同源物,编码的蛋白质,它是小GTP酶超家族的成员。单一氨基酸取代是负责活化突变。该成果转化蛋白在各种恶性肿瘤,包括肺腺癌,粘液瘤,胰腺和结直肠癌性导管癌牵连。选择性剪接导致变体编码两种亚型,在C-末端区域不同。 [由RefSeq的,2008年7月提供]
KRAS基因(以及对应的蛋白质)的细胞分布位置:
KRAS基因的本体(GO)信息:
疾病名称 | 关系值 | NofPmids | NofSnps | 来源 |
Juvenile Myelomonocytic Leukemia | 0.447805801 | 12 | 3 | BeFree_CLINVAR_CTD_human_GAD_LHGDN_MGD_ORPHANET |
NOONAN SYNDROME 3 | 0.44 | 3 | 14 | CLINVAR_CTD_human_MGD_UNIPROT |
Colorectal Neoplasms | 0.322443416 | 95 | 1 | BeFree_CTD_human_GAD_LHGDN_RGD |
Non-Small Cell Lung Carcinoma | 0.321301873 | 222 | 13 | BeFree_CLINVAR_CTD_human_GAD_LHGDN |
Adenocarcinoma | 0.309144846 | 243 | 3 | BeFree_CTD_human_GAD_LHGDN |
Noonan Syndrome | 0.264970109 | 33 | 2 | BeFree_CTD_human_GAD_LHGDN_ORPHANET |
ovarian neoplasm | 0.255992664 | 20 | 2 | BeFree_CLINVAR_CTD_human_GAD_LHGDN |
Stomach Neoplasms | 0.25581703 | 10 | 2 | BeFree_CLINVAR_CTD_human_GAD_LHGDN |
Cardio-facio-cutaneous syndrome | 0.244071628 | 16 | 3 | BeFree_CTD_human_ORPHANET |
Pilocytic Astrocytoma | 0.240542884 | 2 | 1 | BeFree_CLINVAR_ORPHANET |
RAS-ASSOCIATED AUTOIMMUNE LEUKOPROLIFERATIVE DISORDER | 0.24 | 0 | 3 | CLINVAR_ORPHANET |
CARDIOFACIOCUTANEOUS SYNDROME 2 | 0.24 | 4 | 7 | CLINVAR_UNIPROT |
Nevus sebaceous | 0.24 | 1 | 0 | CTD_human_ORPHANET |
Carcinoma of lung | 0.22904428 | 107 | 2 | BeFree_CLINVAR_MGD |
Pancreatic carcinoma | 0.22815401 | 96 | 1 | BeFree_CLINVAR_GAD_MGD |
Lung Neoplasms | 0.221454344 | 99 | 1 | BeFree_CTD_human_GAD_LHGDN |
Pancreatic Neoplasm | 0.175466202 | 39 | 0 | BeFree_CTD_human_GAD_LHGDN |
Colonic Neoplasms | 0.167750158 | 38 | 3 | BeFree_CTD_human_GAD_LHGDN |
Neoplasm Metastasis | 0.163332349 | 113 | 5 | BeFree_CTD_human_GAD_LHGDN |
Adenoma | 0.160104841 | 72 | 2 | BeFree_CTD_human_GAD_LHGDN |
Colorectal Cancer | 0.16 | 522 | 6 | BeFree_GAD |
Squamous cell carcinoma | 0.155276307 | 36 | 1 | BeFree_CTD_human_GAD_LHGDN |
Carcinogenesis | 0.149315722 | 109 | 6 | BeFree_CTD_human |
Adenocarcinoma of lung (disorder) | 0.145711033 | 89 | 2 | BeFree_CTD_human_GAD |
Thyroid Neoplasm | 0.139922334 | 9 | 0 | BeFree_CTD_human_GAD_LHGDN |
Endometrial Carcinoma | 0.130238846 | 29 | 5 | BeFree_CLINVAR_GAD |
Carcinoma, Pancreatic Ductal | 0.129468128 | 5 | 0 | CTD_human_GAD |
Endometriosis | 0.129087065 | 9 | 0 | BeFree_CTD_human_GAD_LHGDN |
Leukemia, Myelocytic, Acute | 0.129087065 | 9 | 1 | BeFree_CLINVAR_GAD_LHGDN |
Cholangiocarcinoma | 0.126710102 | 19 | 1 | BeFree_CTD_human_GAD |
Stomach Carcinoma | 0.126514605 | 24 | 1 | BeFree_UNIPROT |
Liver neoplasms | 0.12554839 | 7 | 0 | BeFree_CTD_human_GAD |
Malignant neoplasm of urinary bladder | 0.125276948 | 4 | 1 | BeFree_CLINVAR_GAD |
Bladder Neoplasm | 0.125091382 | 2 | 0 | CTD_human_GAD_LHGDN |
Mouth Neoplasms | 0.124734064 | 3 | 0 | CTD_human_GAD |
Papillary thyroid carcinoma | 0.123995683 | 7 | 1 | BeFree_GAD_ORPHANET |
Hemangiosarcoma | 0.123538676 | 7 | 0 | BeFree_CTD_human_LHGDN |
Liver carcinoma | 0.123257302 | 12 | 0 | BeFree_CTD_human |
Neuroblastoma | 0.122909916 | 3 | 1 | BeFree_CTD_human_GAD |
Astrocytoma | 0.12272435 | 2 | 0 | CTD_human_LHGDN |
Hereditary Nonpolyposis Colorectal Cancer | 0.122442977 | 9 | 1 | BeFree_ORPHANET |
Costello syndrome (disorder) | 0.122171535 | 9 | 2 | BeFree_CTD_human |
Mammary Neoplasms | 0.121085767 | 4 | 0 | BeFree_CTD_human |
Lymphoma | 0.120542884 | 3 | 0 | BeFree_CTD_human |
Squamous cell carcinoma of lung | 0.120542884 | 2 | 1 | BeFree_CLINVAR |
Nasopharyngeal carcinoma | 0.120542884 | 3 | 0 | BeFree_CTD_human |
NEVUS, EPIDERMAL (disorder) | 0.120271442 | 1 | 1 | BeFree_CLINVAR |
Cecal Neoplasms | 0.12 | 1 | 0 | CTD_human |
gallbladder neoplasm | 0.12 | 1 | 0 | CTD_human |
Liver Diseases, Parasitic | 0.12 | 1 | 0 | CTD_human |
Liver Neoplasms, Experimental | 0.12 | 1 | 0 | CTD_human |
Neoplasms, Experimental | 0.12 | 4 | 0 | CTD_human |
Penile Neoplasms | 0.12 | 1 | 0 | CTD_human |
Uterine Neoplasms | 0.12 | 1 | 0 | CTD_human |
Medullary carcinoma of thyroid | 0.12 | 0 | 1 | CLINVAR |
Breast adenocarcinoma | 0.12 | 0 | 1 | CLINVAR |
APLASIA CUTIS CONGENITA WITH EPIBULBAR DERMOIDS | 0.12 | 0 | 0 | ORPHANET |
Pancreatic carcinoma, familial | 0.12 | 0 | 0 | ORPHANET |
Juvenile arthritis | 0.12 | 1 | 0 | CTD_human |
Malignant neoplasm of lung | 0.11338735 | 161 | 3 | BeFree_GAD |
Endometrial Neoplasms | 0.100279652 | 10 | 0 | BeFree_GAD_LHGDN_RGD |
Colorectal Carcinoma | 0.082367032 | 488 | 6 | BeFree_GAD |
Malignant neoplasm of prostate | 0.082171535 | 8 | 0 | BeFree_MGD |
Kidney Failure, Chronic | 0.08 | 1 | 0 | RGD |
Sarcoma, Experimental | 0.08 | 1 | 0 | RGD |
Colorectal cancer metastatic | 0.08 | 296 | 3 | BeFree |
ENDOMETRIOSIS, SUSCEPTIBILITY TO, 1 | 0.08 | 0 | 0 | MGD |
LUNG CANCER SUSCEPTIBILITY 3 | 0.08 | 0 | 0 | MGD |
Microsatellite Instability | 0.03550548 | 15 | 0 | GAD |
Malignant neoplasm of pancreas | 0.035255106 | 99 | 0 | BeFree_GAD |
Rectal Neoplasms | 0.025298971 | 14 | 4 | BeFree_GAD |
Malignant tumor of colon | 0.024625265 | 83 | 4 | BeFree_GAD |
Colon Carcinoma | 0.024158327 | 89 | 4 | BeFree |
Malignant neoplasm of ovary | 0.016992555 | 21 | 1 | BeFree_GAD |
Hyperplasia | 0.015274147 | 5 | 0 | GAD_LHGDN |
Malignant neoplasm of stomach | 0.013887143 | 27 | 1 | BeFree_GAD |
polyps | 0.01387333 | 23 | 1 | BeFree_LHGDN |
Precursor Cell Lymphoblastic Leukemia Lymphoma | 0.013449998 | 6 | 0 | BeFree_GAD_LHGDN |
Colonic Polyps | 0.012106602 | 6 | 0 | BeFree_GAD |
Mucinous Adenocarcinoma | 0.011801484 | 19 | 0 | BeFree_GAD_LHGDN |
Pancreatic Ductal Adenocarcinoma | 0.011400559 | 42 | 1 | BeFree |
Rectal Carcinoma | 0.010434343 | 22 | 0 | BeFree_GAD |
Neoplasm Recurrence, Local | 0.009468128 | 4 | 0 | GAD |
Pancreatitis, Chronic | 0.009444384 | 7 | 0 | BeFree_GAD_LHGDN |
Carcinoma, Large Cell | 0.008630058 | 4 | 0 | BeFree_GAD_LHGDN |
Bronchioloalveolar Adenocarcinoma | 0.008544182 | 6 | 0 | BeFree_GAD_LHGDN |
Malignant neoplasm of breast | 0.007795869 | 20 | 2 | BeFree_GAD |
Adenomatous Polyposis Coli | 0.007719925 | 13 | 0 | BeFree_GAD |
Myeloid Leukemia | 0.00764398 | 5 | 0 | BeFree_GAD |
Cystadenocarcinoma, Serous | 0.00764398 | 5 | 0 | BeFree_GAD |
Carcinoma, Papillary | 0.007372538 | 4 | 0 | BeFree_GAD |
Esophageal Neoplasms | 0.007372538 | 4 | 0 | BeFree_GAD |
Hepatitis C | 0.007057489 | 26 | 0 | BeFree |
Secondary malignant neoplasm of liver | 0.007057489 | 26 | 1 | BeFree |
Ovarian Carcinoma | 0.006514605 | 24 | 1 | BeFree |
Precancerous Conditions | 0.006091273 | 7 | 0 | BeFree_GAD |
Adenocarcinoma of pancreas | 0.005971721 | 22 | 0 | BeFree |
Endometrial Hyperplasia | 0.005634266 | 3 | 0 | BeFree_GAD_LHGDN |
Breast Carcinoma | 0.005428837 | 20 | 2 | BeFree |
melanoma | 0.005167327 | 9 | 1 | BeFree_LHGDN |
Malignant neoplasm of esophagus | 0.005005506 | 3 | 0 | BeFree_GAD |
Papillary adenocarcinoma | 0.004734064 | 2 | 0 | GAD |
Head and Neck Neoplasms | 0.004734064 | 2 | 0 | GAD |
Lymphatic Metastasis | 0.004734064 | 2 | 0 | GAD |
Neoplasms, Glandular and Epithelial | 0.004734064 | 2 | 0 | GAD |
Chromosomal Instability | 0.004734064 | 2 | 0 | GAD |
leukemia | 0.004353001 | 7 | 0 | BeFree_LHGDN |
Tumor Progression | 0.00434307 | 16 | 1 | BeFree |
Myeloid Leukemia, Chronic | 0.00408156 | 6 | 1 | BeFree_LHGDN |
Gastrointestinal Stromal Tumors | 0.003995683 | 7 | 0 | BeFree_GAD |
Sarcoma | 0.003995683 | 6 | 0 | BeFree_GAD |
Malignant neoplasm of endometrium | 0.003800186 | 14 | 3 | BeFree |
Secondary malignant neoplasm of lymph node | 0.003800186 | 14 | 1 | BeFree |
Uterine Corpus Cancer | 0.003800186 | 14 | 3 | BeFree |
Pancreatitis | 0.003538676 | 4 | 0 | BeFree_LHGDN |
Epithelial ovarian cancer | 0.003528744 | 13 | 1 | BeFree |
Leukemia, Myelomonocytic, Chronic | 0.003452799 | 5 | 0 | BeFree_GAD |
Carcinoma, Endometrioid | 0.003452799 | 5 | 0 | BeFree_GAD |
Glioblastoma | 0.003267234 | 3 | 0 | BeFree_LHGDN |
Cystadenoma, Serous | 0.003267234 | 2 | 0 | BeFree_LHGDN |
Adenocarcinoma of large intestine | 0.003257302 | 12 | 0 | BeFree |
Thyroid Nodule | 0.003181358 | 4 | 1 | BeFree_GAD |
Hemangioma | 0.002995792 | 1 | 0 | BeFree_LHGDN |
Adenoma of large intestine | 0.002985861 | 11 | 0 | BeFree |
Renal Cell Carcinoma | 0.002909916 | 2 | 0 | BeFree_GAD |
Carcinoma, Transitional Cell | 0.002909916 | 3 | 0 | BeFree_GAD |
Exanthema | 0.002909916 | 3 | 0 | BeFree_GAD |
Inflammatory Bowel Diseases | 0.002909916 | 3 | 0 | BeFree_GAD |
Preleukemia | 0.002909916 | 3 | 0 | BeFree_GAD |
Adenosquamous carcinoma | 0.002909916 | 3 | 0 | BeFree_GAD |
Lichen Sclerosus et Atrophicus | 0.00272435 | 1 | 0 | LHGDN |
Mesothelioma | 0.00272435 | 1 | 0 | LHGDN |
Metaplasia | 0.00272435 | 1 | 0 | LHGDN |
T-Cell Lymphoma | 0.00272435 | 1 | 0 | LHGDN |
Hyperplastic Polyp | 0.002714419 | 10 | 0 | BeFree |
Hypertrophic Cardiomyopathy | 0.002638474 | 2 | 0 | BeFree_GAD |
Glioma | 0.002638474 | 2 | 0 | BeFree_GAD |
HIV Infections | 0.002638474 | 2 | 0 | BeFree_GAD |
Immunologic Deficiency Syndromes | 0.002638474 | 2 | 1 | BeFree_GAD |
Lymphoma, Non-Hodgkin | 0.002638474 | 2 | 0 | BeFree_GAD |
Meningioma | 0.002638474 | 2 | 0 | BeFree_GAD |
Neurofibromatosis 1 | 0.002638474 | 2 | 1 | BeFree_GAD |
Neutropenia | 0.002638474 | 2 | 0 | BeFree_GAD |
Prostatic Neoplasms | 0.002638474 | 2 | 0 | BeFree_GAD |
Retinoblastoma | 0.002638474 | 2 | 0 | BeFree_GAD |
Cancer of Head and Neck | 0.002638474 | 2 | 0 | BeFree_GAD |
Secondary malignant neoplasm of lung | 0.002442977 | 9 | 0 | BeFree |
Adenocarcinoma of colon | 0.002442977 | 9 | 0 | BeFree |
Prostate carcinoma | 0.002442977 | 9 | 0 | BeFree |
Alcoholic Intoxication, Chronic | 0.002367032 | 1 | 0 | GAD |
Anus Neoplasms | 0.002367032 | 1 | 0 | GAD |
Biliary Tract Neoplasm | 0.002367032 | 1 | 0 | GAD |
Chromosome Aberrations | 0.002367032 | 1 | 0 | GAD |
Chromosome Deletion | 0.002367032 | 1 | 0 | GAD |
Hereditary Nonpolyposis Colorectal Neoplasms | 0.002367032 | 1 | 0 | GAD |
Common Bile Duct Neoplasms | 0.002367032 | 1 | 0 | GAD |
Diarrhea | 0.002367032 | 1 | 0 | GAD |
Pathological Dilatation | 0.002367032 | 1 | 0 | GAD |
Eosinophilia | 0.002367032 | 1 | 0 | GAD |
Gingival Neoplasms | 0.002367032 | 1 | 0 | GAD |
Congenital Heart Defects | 0.002367032 | 1 | 0 | GAD |
Heart Diseases | 0.002367032 | 1 | 1 | GAD |
Inflammation | 0.002367032 | 1 | 0 | GAD |
Kidney Neoplasm | 0.002367032 | 1 | 0 | GAD |
Lymphoid leukemia | 0.002367032 | 1 | 0 | GAD |
Chronic Obstructive Airway Disease | 0.002367032 | 1 | 0 | GAD |
Mandibular Neoplasms | 0.002367032 | 1 | 0 | GAD |
Maxillary Neoplasms | 0.002367032 | 1 | 0 | GAD |
Nausea | 0.002367032 | 1 | 0 | GAD |
Neoplasm Invasiveness | 0.002367032 | 1 | 0 | GAD |
Neoplasms, Germ Cell and Embryonal | 0.002367032 | 1 | 0 | GAD |
Neoplasms, Multiple Primary | 0.002367032 | 1 | 0 | GAD |
Paranasal Sinus Neoplasms | 0.002367032 | 1 | 0 | GAD |
Pulmonary Valve Stenosis | 0.002367032 | 1 | 0 | GAD |
Skin Abnormalities | 0.002367032 | 1 | 0 | GAD |
Testicular Neoplasms | 0.002367032 | 1 | 0 | GAD |
Thyroid Diseases | 0.002367032 | 1 | 0 | GAD |
Tongue Neoplasms | 0.002367032 | 1 | 0 | GAD |
Tonsillar Neoplasms | 0.002367032 | 1 | 0 | GAD |
Neoplasms, Second Primary | 0.002367032 | 1 | 0 | GAD |
LEOPARD Syndrome | 0.002367032 | 1 | 0 | GAD |
Adenomatosis, Pulmonary | 0.002367032 | 1 | 0 | GAD |
Papillary and follicular adenocarcinoma | 0.002367032 | 1 | 0 | GAD |
Medullary carcinoma | 0.002367032 | 1 | 0 | GAD |
Cystadenocarcinoma, Mucinous | 0.002367032 | 1 | 0 | GAD |
Carcinoma, Giant Cell | 0.002367032 | 1 | 0 | GAD |
Nerve Sheath Tumors | 0.002367032 | 1 | 0 | GAD |
Retinal Neoplasms | 0.002367032 | 1 | 0 | GAD |
Papillomavirus Infections | 0.002367032 | 1 | 0 | GAD |
Necrotic changes (finding) | 0.002367032 | 1 | 0 | GAD |
MYELODYSPLASTIC SYNDROME | 0.002367032 | 1 | 0 | GAD |
Adenoma of lung | 0.002171535 | 8 | 0 | BeFree |
Ulcerative Colitis | 0.001900093 | 7 | 0 | BeFree |
Stage III Colon Cancer | 0.001900093 | 7 | 0 | BeFree |
Non-Neoplastic Disorder | 0.001900093 | 7 | 0 | BeFree |
Malignant neoplasm of thyroid | 0.001628651 | 6 | 2 | BeFree |
Dengue Fever | 0.001628651 | 6 | 0 | BeFree |
Metastatic malignant neoplasm to brain | 0.001628651 | 6 | 0 | BeFree |
Intrahepatic Cholangiocarcinoma | 0.001628651 | 6 | 0 | BeFree |
Thyroid carcinoma | 0.001628651 | 6 | 2 | BeFree |
Progressive Neoplastic Disease | 0.001628651 | 6 | 0 | BeFree |
Skin toxicity | 0.001628651 | 6 | 1 | BeFree |
Squamous cell carcinoma of the head and neck | 0.001628651 | 6 | 0 | BeFree |
Traditional Serrated Adenoma | 0.001628651 | 6 | 0 | BeFree |
Rectal Tumors | 0.001628651 | 6 | 4 | BeFree |
Rash and Dermatitis Adverse Event Associated with Chemoradiation | 0.001628651 | 6 | 1 | BeFree |
Stage III Colon Cancer AJCC v7 | 0.001628651 | 6 | 0 | BeFree |
Progressive cGVHD | 0.001628651 | 6 | 0 | BeFree |
Congenital chromosomal disease | 0.001357209 | 5 | 0 | BeFree |
Pancreatic Cyst | 0.001357209 | 5 | 0 | BeFree |
Gallbladder Carcinoma | 0.001357209 | 5 | 0 | BeFree |
Solid tumour | 0.001357209 | 5 | 0 | BeFree |
Hepatitis C, Chronic | 0.001357209 | 5 | 0 | BeFree |
Endometrial adenocarcinoma | 0.001357209 | 5 | 0 | BeFree |
Mucinous Neoplasm | 0.001357209 | 5 | 0 | BeFree |
Seminoma | 0.001085767 | 4 | 0 | BeFree |
Gastric adenoma | 0.001085767 | 4 | 0 | BeFree |
Adenocarcinoma of rectum | 0.001085767 | 4 | 0 | BeFree |
Germ cell tumor | 0.001085767 | 4 | 0 | BeFree |
Non-small cell lung cancer metastatic | 0.001085767 | 4 | 0 | BeFree |
Squamous cell carcinoma of esophagus | 0.001085767 | 4 | 0 | BeFree |
Angiosarcoma of liver | 0.001085767 | 4 | 0 | BeFree |
Recurrent tumor | 0.001085767 | 4 | 0 | BeFree |
Malignant neoplasm of gastrointestinal tract | 0.001085767 | 4 | 0 | BeFree |
Adenocarcinoma of lung, stage IV | 0.001085767 | 4 | 0 | BeFree |
Intraepithelial Neoplasia | 0.001085767 | 4 | 1 | BeFree |
Pancreatic intraepithelial neoplasia | 0.001085767 | 4 | 0 | BeFree |
Serrated polyp | 0.001085767 | 4 | 0 | BeFree |
MUTYH-Associate Polyposis | 0.001085767 | 4 | 0 | BeFree |
Cyst | 0.000814326 | 3 | 0 | BeFree |
Dermoid Cyst | 0.000814326 | 3 | 0 | BeFree |
Acute lymphocytic leukemia | 0.000814326 | 3 | 0 | BeFree |
Multiple Myeloma | 0.000814326 | 3 | 0 | BeFree |
Pancreatic Diseases | 0.000814326 | 3 | 0 | BeFree |
Rhabdomyosarcoma | 0.000814326 | 3 | 1 | BeFree |
Thymoma | 0.000814326 | 3 | 4 | BeFree |
Malignant neoplasm of gallbladder | 0.000814326 | 3 | 0 | BeFree |
Adenoma, Villous | 0.000814326 | 3 | 0 | BeFree |
Adenomatous Polyps | 0.000814326 | 3 | 0 | BeFree |
Follicular thyroid carcinoma | 0.000814326 | 3 | 1 | BeFree |
Acinar Cell Carcinoma | 0.000814326 | 3 | 0 | BeFree |
Turcot syndrome (disorder) | 0.000814326 | 3 | 0 | BeFree |
Non-small cell lung cancer stage III | 0.000814326 | 3 | 1 | BeFree |
Tumor necrosis | 0.000814326 | 3 | 0 | BeFree |
Tubulovillous adenoma | 0.000814326 | 3 | 0 | BeFree |
Serous cystadenoma, borderline malignancy | 0.000814326 | 3 | 0 | BeFree |
Biliary Intraepithelial Neoplasia | 0.000814326 | 3 | 0 | BeFree |
invasive cancer | 0.000814326 | 3 | 0 | BeFree |
Carcinoma of bladder | 0.000814326 | 3 | 0 | BeFree |
Dissecting aneurysm of the thoracic aorta | 0.000814326 | 3 | 0 | BeFree |
Rhabdoid Tumor of the Kidney | 0.000814326 | 3 | 0 | BeFree |
Ductal Carcinoma | 0.000814326 | 3 | 0 | BeFree |
Ductal Breast Carcinoma | 0.000814326 | 3 | 0 | BeFree |
Low grade serous carcinoma | 0.000814326 | 3 | 0 | BeFree |
Ataxia Telangiectasia | 0.000542884 | 2 | 0 | BeFree |
Brain Neoplasms | 0.000542884 | 2 | 1 | BeFree |
Adenocarcinoma of prostate | 0.000542884 | 2 | 0 | BeFree |
Carcinosarcoma | 0.000542884 | 2 | 1 | BeFree |
Developmental Disabilities | 0.000542884 | 2 | 0 | BeFree |
Craniosynostosis | 0.000542884 | 2 | 0 | BeFree |
Cystadenoma | 0.000542884 | 2 | 0 | BeFree |
pathologic fistula | 0.000542884 | 2 | 0 | BeFree |
Hepatitis, Chronic | 0.000542884 | 2 | 0 | BeFree |
Liver diseases | 0.000542884 | 2 | 0 | BeFree |
Neck Neoplasms | 0.000542884 | 2 | 0 | BeFree |
Nephroblastoma | 0.000542884 | 2 | 0 | BeFree |
Obesity | 0.000542884 | 2 | 0 | BeFree |
Uterine Fibroids | 0.000542884 | 2 | 0 | BeFree |
Virus Diseases | 0.000542884 | 2 | 0 | BeFree |
Epstein-Barr Virus Infections | 0.000542884 | 2 | 0 | BeFree |
Esophageal carcinoma | 0.000542884 | 2 | 0 | BeFree |
Malignant neoplasm of mouth | 0.000542884 | 2 | 0 | BeFree |
Uterine Cancer | 0.000542884 | 2 | 0 | BeFree |
Malignant neoplasm of brain | 0.000542884 | 2 | 0 | BeFree |
Secondary malignant neoplasm of bone | 0.000542884 | 2 | 0 | BeFree |
Carcinoma, Spindle-Cell | 0.000542884 | 2 | 1 | BeFree |
Thymic Carcinoma | 0.000542884 | 2 | 4 | BeFree |
Stage II Colon Cancer | 0.000542884 | 2 | 0 | BeFree |
Malignant neoplasm of colon stage IV | 0.000542884 | 2 | 0 | BeFree |
Adenocarcinoma of small intestine | 0.000542884 | 2 | 0 | BeFree |
Metastatic melanoma | 0.000542884 | 2 | 0 | BeFree |
Cervical Squamous Cell Carcinoma | 0.000542884 | 2 | 2 | BeFree |
Cervical Adenocarcinoma | 0.000542884 | 2 | 0 | BeFree |
Ovarian Teratoma | 0.000542884 | 2 | 0 | BeFree |
stage, non-small cell lung cancer | 0.000542884 | 2 | 0 | BeFree |
Triploidy syndrome | 0.000542884 | 2 | 0 | BeFree |
Pleomorphic carcinoma | 0.000542884 | 2 | 0 | BeFree |
Tubular adenoma | 0.000542884 | 2 | 0 | BeFree |
Breast Cancer, Familial | 0.000542884 | 2 | 1 | BeFree |
Multiple malignancy | 0.000542884 | 2 | 0 | BeFree |
Disseminated Malignant Neoplasm | 0.000542884 | 2 | 0 | BeFree |
Secondary malignant neoplasm of pancreas | 0.000542884 | 2 | 0 | BeFree |
Hematologic Neoplasms | 0.000542884 | 2 | 0 | BeFree |
Hereditary Breast and Ovarian Cancer Syndrome | 0.000542884 | 2 | 1 | BeFree |
Refractory cancer | 0.000542884 | 2 | 0 | BeFree |
Stage II Colorectal Cancer | 0.000542884 | 2 | 0 | BeFree |
Stage IV Colorectal Cancer | 0.000542884 | 2 | 0 | BeFree |
Central neuroblastoma | 0.000542884 | 2 | 0 | BeFree |
Biliary Tract Cancer | 0.000542884 | 2 | 0 | BeFree |
Advanced cancer | 0.000542884 | 2 | 0 | BeFree |
precancerous lesions | 0.000542884 | 2 | 0 | BeFree |
Intestinal adenocarcinoma | 0.000542884 | 2 | 0 | BeFree |
Autoimmune Lymphoproliferative Syndrome | 0.000542884 | 2 | 0 | BeFree |
Childhood Leukemia | 0.000542884 | 2 | 0 | BeFree |
High Grade Intraepithelial Neoplasia | 0.000542884 | 2 | 0 | BeFree |
Ovarian Serous Adenocarcinoma | 0.000542884 | 2 | 0 | BeFree |
Well Differentiated Pancreatic Endocrine Tumor | 0.000542884 | 2 | 0 | BeFree |
Epithelioma | 0.000542884 | 2 | 0 | BeFree |
Mammary Tumorigenesis | 0.000542884 | 2 | 0 | BeFree |
Cancer Cell Growth | 0.000542884 | 2 | 0 | BeFree |
Xenograft Model | 0.000542884 | 2 | 0 | BeFree |
Adenocarcinoma, Endometrioid | 0.000542884 | 2 | 0 | BeFree |
ECTRODACTYLY, ECTODERMAL DYSPLASIA, AND CLEFT LIP/PALATE SYNDROME 1 | 0.000542884 | 2 | 0 | BeFree |
Urothelial Carcinoma | 0.000542884 | 2 | 0 | BeFree |
Hyperdiploid B Acute Lymphoblastic Leukemia | 0.000542884 | 2 | 0 | BeFree |
Sessile Serrated Adenoma/Polyp | 0.000542884 | 2 | 0 | BeFree |
Chronic ulcerative colitis | 0.000542884 | 2 | 0 | BeFree |
Stage IV Colorectal Cancer AJCC v7 | 0.000542884 | 2 | 0 | BeFree |
Stage II Colorectal Cancer AJCC v7 | 0.000542884 | 2 | 0 | BeFree |
Stage II Colon Cancer AJCC v7 | 0.000542884 | 2 | 0 | BeFree |
Serrated adenocarcinoma | 0.000542884 | 2 | 0 | BeFree |
Triple Negative Breast Neoplasms | 0.000542884 | 2 | 0 | BeFree |
Brenner Tumor | 0.000271442 | 1 | 0 | BeFree |
Malignant tumor of cervix | 0.000271442 | 1 | 0 | BeFree |
Cholestasis | 0.000271442 | 1 | 0 | BeFree |
Colonic Diseases | 0.000271442 | 1 | 0 | BeFree |
Adenoid Cystic Carcinoma | 0.000271442 | 1 | 1 | BeFree |
Cystadenoma, Mucinous | 0.000271442 | 1 | 0 | BeFree |
Dry Eye Syndromes | 0.000271442 | 1 | 0 | BeFree |
Dwarfism | 0.000271442 | 1 | 0 | BeFree |
Eyelid Neoplasms | 0.000271442 | 1 | 0 | BeFree |
Fatigue | 0.000271442 | 1 | 0 | BeFree |
Flatulence | 0.000271442 | 1 | 0 | BeFree |
Gastritis, Atrophic | 0.000271442 | 1 | 0 | BeFree |
Giant Cell Tumors | 0.000271442 | 1 | 0 | BeFree |
granulosa cell tumor | 0.000271442 | 1 | 0 | BeFree |
Cardiac Arrest | 0.000271442 | 1 | 0 | BeFree |
Hepatitis | 0.000271442 | 1 | 0 | BeFree |
Hepatitis A | 0.000271442 | 1 | 0 | BeFree |
Hodgkin Disease | 0.000271442 | 1 | 0 | BeFree |
Seborrheic keratosis | 0.000271442 | 1 | 0 | BeFree |
Fibroid Tumor | 0.000271442 | 1 | 0 | BeFree |
leiomyosarcoma | 0.000271442 | 1 | 0 | BeFree |
Leukopenia | 0.000271442 | 1 | 0 | BeFree |
Lipoma | 0.000271442 | 1 | 1 | BeFree |
Liver Cirrhosis | 0.000271442 | 1 | 0 | BeFree |
Lupus Erythematosus, Systemic | 0.000271442 | 1 | 0 | BeFree |
Primary malignant neoplasm of liver | 0.000271442 | 1 | 0 | BeFree |
Premature Menopause | 0.000271442 | 1 | 1 | BeFree |
Mixed Salivary Gland Tumor | 0.000271442 | 1 | 0 | BeFree |
Monoclonal Gammopathy of Undetermined Significance | 0.000271442 | 1 | 0 | BeFree |
Mucocele | 0.000271442 | 1 | 0 | BeFree |
Neoplastic Syndromes, Hereditary | 0.000271442 | 1 | 0 | BeFree |
Neurilemmoma | 0.000271442 | 1 | 1 | BeFree |
Peutz-Jeghers Syndrome | 0.000271442 | 1 | 0 | BeFree |
Pseudotumor | 0.000271442 | 1 | 0 | BeFree |
Sezary Syndrome | 0.000271442 | 1 | 4 | BeFree |
Struma Ovarii | 0.000271442 | 1 | 0 | BeFree |
Thrombocythemia, Essential | 0.000271442 | 1 | 0 | BeFree |
Tuberous Sclerosis | 0.000271442 | 1 | 0 | BeFree |
Turner Syndrome | 0.000271442 | 1 | 0 | BeFree |
Severe Combined Immunodeficiency | 0.000271442 | 1 | 0 | BeFree |
Ovarian Failure, Premature | 0.000271442 | 1 | 1 | BeFree |
Burning sensation | 0.000271442 | 1 | 0 | BeFree |
Benign Neoplasm | 0.000271442 | 1 | 0 | BeFree |
Chronic Persistent Hepatitis | 0.000271442 | 1 | 0 | BeFree |
Atrophic condition of skin | 0.000271442 | 1 | 0 | BeFree |
Cutaneous Melanoma | 0.000271442 | 1 | 0 | BeFree |
Dry skin | 0.000271442 | 1 | 0 | BeFree |
Granulocytic Sarcoma | 0.000271442 | 1 | 0 | BeFree |
Malignant neoplasm of oropharynx | 0.000271442 | 1 | 0 | BeFree |
Malignant neoplasm of anus | 0.000271442 | 1 | 0 | BeFree |
Malignant neoplasm of testis | 0.000271442 | 1 | 0 | BeFree |
Malignant neoplasm of penis | 0.000271442 | 1 | 0 | BeFree |
Uterine Polyp | 0.000271442 | 1 | 0 | BeFree |
Acute intermittent porphyria | 0.000271442 | 1 | 0 | BeFree |
Neurofibromatoses | 0.000271442 | 1 | 1 | BeFree |
Undifferentiated carcinoma | 0.000271442 | 1 | 0 | BeFree |
Hepatoblastoma | 0.000271442 | 1 | 1 | BeFree |
Pulmonary Blastoma | 0.000271442 | 1 | 0 | BeFree |
Rhabdomyosarcoma, Embryonal | 0.000271442 | 1 | 1 | BeFree |
Hepatocellular Adenoma | 0.000271442 | 1 | 1 | BeFree |
Sebaceous Adenocarcinoma | 0.000271442 | 1 | 0 | BeFree |
Adrenocortical carcinoma | 0.000271442 | 1 | 0 | BeFree |
Carcinoma, Signet Ring Cell | 0.000271442 | 1 | 0 | BeFree |
Nevus, Blue | 0.000271442 | 1 | 0 | BeFree |
Neuroendocrine Tumors | 0.000271442 | 1 | 0 | BeFree |
Adenocarcinoma of appendix | 0.000271442 | 1 | 0 | BeFree |
Carcinoma of ampulla of Vater | 0.000271442 | 1 | 0 | BeFree |
Organoid Nevus Phakomatosis | 0.000271442 | 1 | 0 | BeFree |
Ectopic gastric tissue | 0.000271442 | 1 | 0 | BeFree |
Somatotropin deficiency | 0.000271442 | 1 | 0 | BeFree |
Coinfection | 0.000271442 | 1 | 0 | BeFree |
Chronic viral hepatitis | 0.000271442 | 1 | 0 | BeFree |
Carcinoma breast stage IV | 0.000271442 | 1 | 0 | BeFree |
Non-small cell lung cancer stage II | 0.000271442 | 1 | 0 | BeFree |
Non-small cell lung cancer recurrent | 0.000271442 | 1 | 0 | BeFree |
Anal cancer recurrent | 0.000271442 | 1 | 0 | BeFree |
Endometrial neoplasm malignant metastatic | 0.000271442 | 1 | 0 | BeFree |
Adenocarcinoma Of Esophagus | 0.000271442 | 1 | 0 | BeFree |
Anal carcinoma | 0.000271442 | 1 | 0 | BeFree |
Gallbladder adenocarcinoma | 0.000271442 | 1 | 0 | BeFree |
Bladder Adenocarcinoma | 0.000271442 | 1 | 0 | BeFree |
Carcinoid tumor of lung | 0.000271442 | 1 | 0 | BeFree |
Squamous cell carcinoma of oropharynx | 0.000271442 | 1 | 0 | BeFree |
Desmoplastic Small Round Cell Tumor | 0.000271442 | 1 | 0 | BeFree |
Cervix carcinoma | 0.000271442 | 1 | 0 | BeFree |
Dryness of eye | 0.000271442 | 1 | 0 | BeFree |
Squamous cell carcinoma, metastatic | 0.000271442 | 1 | 0 | BeFree |
Lymphoepithelial carcinoma | 0.000271442 | 1 | 0 | BeFree |
Adenocarcinoma in Situ | 0.000271442 | 1 | 0 | BeFree |
Adenocarcinoma, metastatic | 0.000271442 | 1 | 0 | BeFree |
Mucinous cystic tumor of borderline malignancy | 0.000271442 | 1 | 0 | BeFree |
Cellular Blue Nevus | 0.000271442 | 1 | 0 | BeFree |
Proliferating Brenner Tumor | 0.000271442 | 1 | 0 | BeFree |
Malignant neoplasm of liver | 0.000271442 | 1 | 0 | BeFree |
Giant cell carcinoma of lung | 0.000271442 | 1 | 0 | BeFree |
Endometrioid carcinoma ovary | 0.000271442 | 1 | 0 | BeFree |
Atypical Endometrial Hyperplasia | 0.000271442 | 1 | 0 | BeFree |
Malignant lymphoma of testis | 0.000271442 | 1 | 0 | BeFree |
Verrucous epidermal nevus | 0.000271442 | 1 | 1 | BeFree |
Syringocystadenoma Papilliferum | 0.000271442 | 1 | 0 | BeFree |
Trisomy 12 | 0.000271442 | 1 | 0 | BeFree |
Neuropathy | 0.000271442 | 1 | 0 | BeFree |
Papillary neoplasm | 0.000271442 | 1 | 0 | BeFree |
Chronic active hepatitis | 0.000271442 | 1 | 0 | BeFree |
Sessile polyp | 0.000271442 | 1 | 0 | BeFree |
Oropharynx (excludes nasopharynx) | 0.000271442 | 1 | 0 | BeFree |
Ewings sarcoma | 0.000271442 | 1 | 0 | BeFree |
Cerebral metastasis | 0.000271442 | 1 | 0 | BeFree |
Primary sclerosing cholangitis | 0.000271442 | 1 | 0 | BeFree |
Chemical Carcinogenesis | 0.000271442 | 1 | 0 | BeFree |
Biliary stricture | 0.000271442 | 1 | 0 | BeFree |
Terminal illness | 0.000271442 | 1 | 0 | BeFree |
Primary malignant neoplasm of brain | 0.000271442 | 1 | 0 | BeFree |
Sigmoid Cancer | 0.000271442 | 1 | 0 | BeFree |
Malignant Squamous Cell Neoplasm | 0.000271442 | 1 | 0 | BeFree |
Malignant Peripheral Nerve Sheath Tumor | 0.000271442 | 1 | 0 | BeFree |
Lafora Disease | 0.000271442 | 1 | 0 | BeFree |
Adenomatous polyp of colon | 0.000271442 | 1 | 0 | BeFree |
Penis carcinoma | 0.000271442 | 1 | 0 | BeFree |
Metastases to adrenals | 0.000271442 | 1 | 0 | BeFree |
Colorectal cancer recurrent | 0.000271442 | 1 | 0 | BeFree |
Adenocarcinoma of lung, stage I | 0.000271442 | 1 | 0 | BeFree |
Pancolitis | 0.000271442 | 1 | 0 | BeFree |
Gastric hyperplastic polyp | 0.000271442 | 1 | 0 | BeFree |
Erdheim-Chester Disease | 0.000271442 | 1 | 1 | BeFree |
Metastatic Prostate Carcinoma | 0.000271442 | 1 | 0 | BeFree |
Hurthle Cell Tumor | 0.000271442 | 1 | 1 | BeFree |
Invasive Ductal Breast Carcinoma | 0.000271442 | 1 | 0 | BeFree |
Morphologically altered structure | 0.000271442 | 1 | 0 | BeFree |
Single tumor | 0.000271442 | 1 | 0 | BeFree |
Torre-Muir syndrome | 0.000271442 | 1 | 0 | BeFree |
Thymoma, type C | 0.000271442 | 1 | 4 | BeFree |
Adenocarcinoma of ampulla of Vater | 0.000271442 | 1 | 1 | BeFree |
Cerebellar Glioblastoma | 0.000271442 | 1 | 0 | BeFree |
Colorectal Villous Adenoma | 0.000271442 | 1 | 0 | BeFree |
Cystic Neoplasm | 0.000271442 | 1 | 0 | BeFree |
Intramuscular Myxoma | 0.000271442 | 1 | 0 | BeFree |
Invasive Carcinoma | 0.000271442 | 1 | 0 | BeFree |
Periampullary Adenocarcinoma | 0.000271442 | 1 | 0 | BeFree |
Primary Carcinoma | 0.000271442 | 1 | 0 | BeFree |
Stage IB Lung Adenocarcinoma | 0.000271442 | 1 | 0 | BeFree |
Undifferentiated Pancreatic Carcinoma | 0.000271442 | 1 | 0 | BeFree |
Mature Teratoma | 0.000271442 | 1 | 0 | BeFree |
Anal cancer metastatic | 0.000271442 | 1 | 0 | BeFree |
Anal squamous cell carcinoma | 0.000271442 | 1 | 0 | BeFree |
Non-Malignant Ascites Adverse Event | 0.000271442 | 1 | 0 | BeFree |
Cirrhosis | 0.000271442 | 1 | 0 | BeFree |
Benign Prostatic Hyperplasia | 0.000271442 | 1 | 0 | BeFree |
Endometrial Polyp | 0.000271442 | 1 | 0 | BeFree |
Colorectal Signet Ring Cell Carcinoma | 0.000271442 | 1 | 0 | BeFree |
mucinous adenocarcinoma of lung | 0.000271442 | 1 | 0 | BeFree |
Lung Sarcomatoid Carcinoma | 0.000271442 | 1 | 0 | BeFree |
Pyloric Gland Adenoma | 0.000271442 | 1 | 0 | BeFree |
Meningioma, benign, no ICD-O subtype | 0.000271442 | 1 | 0 | BeFree |
Monosomy 7 of Bone Marrow | 0.000271442 | 1 | 0 | BeFree |
eyelids (symptom) | 0.000271442 | 1 | 0 | BeFree |
Oropharyngeal Carcinoma | 0.000271442 | 1 | 0 | BeFree |
Urachal adenocarcinoma | 0.000271442 | 1 | 0 | BeFree |
aggressive cancer | 0.000271442 | 1 | 0 | BeFree |
Intramucosal Adenocarcinoma | 0.000271442 | 1 | 0 | BeFree |
Pancreatic Intraductal Papillary Mucinous Neoplasm, Gastric-Type | 0.000271442 | 1 | 0 | BeFree |
Anorectal adenocarcinoma | 0.000271442 | 1 | 0 | BeFree |
Linear Verrucous Epidermal Nevus | 0.000271442 | 1 | 1 | BeFree |
Colorectal Serrated Adenocarcinoma | 0.000271442 | 1 | 0 | BeFree |
Lipomatosis, Multiple | 0.000271442 | 1 | 1 | BeFree |
Fibromyxosarcoma | 0.000271442 | 1 | 0 | BeFree |
High grade serous carcinoma | 0.000271442 | 1 | 0 | BeFree |
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