KLK11(kallikrein-related peptidase 11) 转至新版数据库

基因基本信息

基因基本信息

基因简称(symbol)
    [HGNC]     [GeneCards]     [NCBI]
基因种类(locus group)
同源简称(alias symbol)
基因家族代码(gene_family_id)
    [HGNC]     [GenScript]
omim代码
entrez码
    [Vega]
vega基因码
ensembl基因码
    [Ensembl]
基因家族(gene family)
refseq数据库代号

更多...

基因种类(locus_type)
基因名称状态(status)
location_sortable
同源基因名称(alias name)
基因名称批准使用时间(date_approved_reserved)
基因简称更名时间(date_symbol_changed)
基因名称更名时间(date_name_changed)
更新时间(date_modified)
ucsc码
ena
ccds数据码
uniprot数据码
pubmed代码
mgd码
rgd码
生命科学数据库(lsdb)
更新时间(date modified)
cosmic
mirbase
基因曾用简称(prev symbol)
基因曾用名称(prev name)
homeodb
cosmic
snornabase
bioparadigms slc
orphanet
假基因信息(pseudogeneorg)
horde id
merops
imgt
iuphar
kznf基因类别
mamit-trnadb
cd
LncRNA数据库
酶代码
中间纤维数据库

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基因染色体位置

基因染色体位置

19q13.33
基因染色体位置图

基因简述

基因简述

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Alternate splicing of this gene results in multiple transcript variants encoding distinct isoforms which are differentially expressed.[provided by RefSeq, Nov 2009]

[中文简述(自动翻译):]  激肽释放酶是具有多种生理功能的丝氨酸蛋白酶的一个亚组。越来越多的证据表明，许多激肽释放酶在肿瘤发生牵连，部分为新的癌症和其他疾病的生物标志物的潜力。该基因是位于群集上染色体19在多个转录该基因的结果的可替代的剪接十五激肽释放酶亚家族成员之一的变体编码这些差异表达不同同种型。[通过的RefSeq，2009年11月提供]

OMIM数据库中对KLK11基因的介绍     Wikipedia数据库中对KLK11基因的介绍

基因序列

基因序列

KLK11基因的碱基序列：[NCBI]

基因突变

基因突变

KLK11基因的碱基突变：           显示全部snp
rs4417638       rs10413969       rs59002782       rs111481992       rs111491193       rs140393218       rs183112210       rs529586562       rs530570164       rs539365247       rs544902449       rs549068164       rs549441005       rs550243028       rs554659893       rs555143999       rs557644304       rs563199303       rs564952699       rs567289009       rs573286136       rs576797975       rs1048328       rs1048344       rs1474520       rs2250066       rs2288892       rs2569457       rs2691208       rs2739436       rs2739437       rs3745538       rs3745539       rs11673638       rs12460414       rs12608873       rs12609283      
rs12979919       rs34766096       rs56740869       rs60627720       rs61729817       rs61750341       rs61752567       rs62117661       rs62117662       rs71333923       rs71333924       rs71333925       rs73591965       rs74882927       rs76090068       rs77435729       rs78101838       rs111482840       rs111591745       rs111847266       rs112018385       rs112352998       rs112388971       rs112443009       rs112466304       rs112633611       rs112865236       rs112964099       rs113023689       rs113277422       rs113369548       rs113444603       rs113502575       rs113977308       rs114226367       rs114498957       rs114845128       rs115072271       rs115554313       rs116010405       rs116137010       rs116538808       rs117191469       rs117218643       rs117268623       rs118067668       rs138078192       rs138271660       rs138758563       rs139007619       rs139119722       rs139849854       rs139862262       rs139868678       rs140606947       rs140954965       rs141243170       rs141595510       rs141778830       rs141845275       rs141977237       rs142044914       rs142185184       rs143043824       rs143216918       rs143218518       rs143406762       rs143774057       rs144171540       rs144412396       rs144772689       rs145128651       rs145172459       rs145388450       rs145437664       rs145496008       rs145979212       rs146041341       rs146244352       rs146364634       rs146423119       rs146501611       rs147813054       rs148167416       rs148309880       rs148371961       rs148855454       rs149169261       rs149219406       rs149645631       rs149689317       rs150197082       rs150404891       rs150670595       rs150718958       rs150723572       rs180786698       rs181450619       rs181452857       rs182003984       rs182161763       rs182329020       rs182794995       rs182980573       rs183668310       rs183708286       rs183746430       rs184437733       rs184561565       rs184609946       rs185262278       rs185364526       rs185447847       rs186344956       rs186565215       rs186813416       rs187414145       rs187694200       rs188307457       rs188544115       rs188617235       rs188760009       rs189112200       rs189395137       rs189433188       rs189684151       rs189802004       rs190229348       rs191149606       rs191156997       rs191286132       rs191299531       rs191413178       rs191424032       rs191916982       rs192651967       rs192775881       rs192846831       rs199568439       rs199597834       rs199754236       rs199945138       rs199952513       rs200000907       rs200295633       rs200362022       rs200411681       rs200477811       rs200479848       rs200566934       rs200588662       rs200643070       rs200838918       rs200856870       rs201145993       rs201147335       rs201201525       rs201211217       rs201296023       rs201449261       rs201468498       rs201481008       rs201524286       rs201757342       rs201833226       rs202087807       rs202178514       rs202213461       rs202231533       rs202243771       rs267605603       rs368209883       rs368582243       rs368774258       rs368783882       rs369004278       rs369449693       rs369580660       rs369629996       rs369654018       rs369745560       rs369986956       rs370034068       rs370146789       rs370302019       rs370372424       rs370419913       rs370733179       rs371133812       rs371728287       rs371739896       rs371858195       rs371953891       rs372135169       rs372189008       rs372680117       rs372936267       rs373492525       rs373536227       rs374113082       rs374127231       rs374161147       rs374359485       rs374684637       rs375064048       rs375260719       rs375701143       rs375958629       rs376079006       rs376188860       rs376997758       rs377099292       rs377138982       rs527972998       rs527974809       rs528010286       rs528174602       rs529387331       rs529407010       rs529645256       rs530304539       rs530434546       rs530535117       rs530684003       rs531224039       rs531522377       rs531649300       rs531854895       rs532094180       rs532281427       rs532923427       rs533051864       rs533460207       rs534027865       rs534065522       rs535556579       rs536686721       rs536894633       rs537717297       rs537938854       rs538276747       rs539170848       rs539400006       rs539901509       rs540342253       rs540389617       rs540480575       rs541051932       rs541168884       rs541307445       rs541521686       rs541542474       rs541545069       rs542875015       rs543725958       rs543935603       rs544594005       rs544829220       rs545036424       rs546014758       rs546617553       rs546649394       rs547810079       rs548407109       rs548443347       rs548951451       rs549034532       rs549350151       rs549743951       rs550166401       rs550298102       rs551016851       rs551212854       rs551826918       rs552122995       rs552138541       rs552341556       rs552380126       rs553329525       rs553374512       rs553411611       rs553620218       rs554811906       rs554827174       rs554859484       rs554866309       rs554898755       rs556016299       rs556142868       rs556156439       rs556264082       rs556356051       rs557178578       rs557509545       rs557715523       rs558210131       rs558505503       rs558542231       rs558730888       rs558802584       rs559261409       rs559870745       rs559924262       rs560453540       rs560695655       rs561049358       rs561882073       rs562295168       rs563359037       rs563685375       rs563692911       rs564344499       rs564706449       rs564879336       rs565014870       rs565506390       rs565844162       rs565977542       rs566081122       rs566687149       rs566955381       rs567019356       rs567192332       rs567910188       rs568453703       rs568500024       rs568586811       rs569362375       rs569618399       rs569641222       rs570042883       rs570049989       rs570520819       rs570523675       rs570574892       rs570655855       rs570695232       rs571229459       rs571268566       rs571335607       rs571798940       rs571999906       rs572990363       rs573993006       rs574236031       rs574302363       rs574436864       rs574465223       rs574500131       rs574751051       rs575438228       rs575475067       rs575530276       rs575684130       rs575691073       rs576365923       rs576672710       rs576702083       rs576797856       rs577083338       rs577178989       rs577546692       rs578141559       rs745337568       rs745414637       rs745520898       rs745599226       rs746090974       rs746183586       rs746262085       rs746477747       rs746554486       rs746582943       rs746675766       rs746762288       rs747223622       rs747552624       rs747600055       rs747927555       rs748463573       rs748657722       rs748658205       rs748926710       rs749057298       rs749178736       rs749236795       rs749451322       rs749835027       rs749970490       rs750029017       rs750274531       rs750729383       rs750879142       rs751298552       rs751597470       rs751668241       rs751774574       rs751991575       rs752124544       rs752475203       rs752487023       rs752613045       rs752801094       rs752851118       rs752951957       rs753143187       rs753227093       rs753375932       rs753518105       rs753632863       rs753721855       rs753885336       rs754168246       rs754514321       rs755017413       rs755159795       rs755177411       rs755371860       rs755483480       rs755593429       rs755679169       rs755917229       rs756042720       rs756051554       rs756518076       rs756605965       rs756712148       rs756728147       rs757089896       rs757264931       rs757286238       rs757427637       rs757431451       rs757800111       rs758082266       rs758180654       rs758286377       rs758382890       rs758447385       rs758568653       rs758646547       rs758920129       rs759071296       rs759212241       rs759476859       rs759534396       rs759564611       rs759630589       rs759672523       rs759848513       rs760040719       rs760246282       rs760420585       rs760508719       rs760614705       rs760718688       rs760771931       rs760859432       rs760994562       rs761162967       rs761194483       rs761443157       rs761813398       rs761940845       rs762203167       rs762243116       rs762293192       rs763084114       rs763356674       rs763964723       rs763988362       rs764072674       rs764224071       rs764363723       rs764377132       rs764602155       rs764647597       rs764799009       rs764880514       rs765025742       rs765126785       rs765151512       rs765390700       rs765607171       rs765778073       rs765819780       rs765901600       rs766191320       rs766274255       rs766282545       rs766449673       rs766636689       rs766647914       rs766741844       rs766821914       rs767224977       rs767312992       rs767486308       rs767491956       rs767632529       rs767682079       rs768011133       rs768224158       rs768276652       rs768293022       rs768320170       rs768799596       rs769074273       rs769267578       rs769314066       rs769356629       rs769371815       rs769456549       rs769651450       rs769713799       rs769800407       rs770136691       rs770357065       rs770444827       rs770476908       rs770553376       rs770749506       rs770925433       rs770927481       rs771002092       rs771024941       rs771658265       rs771688666       rs771691999       rs771732393       rs772122124       rs772157740       rs772462132       rs772490958       rs772494453       rs772636334       rs772781656       rs772815450       rs772904124       rs773436826       rs773471920       rs773497666       rs774016637       rs774217216       rs774324585       rs774406366       rs774412030       rs774499280       rs774901187       rs774977501       rs775279706       rs775283417       rs775528378       rs775655792       rs775922273       rs776036011       rs776038382       rs776314351       rs776423980       rs776611966       rs776696889       rs776720974       rs776782387       rs776886430       rs777058317       rs777262110       rs777368412       rs777451822       rs777780348       rs778105133       rs778278195       rs778385475       rs778575456       rs778874328       rs779044820       rs779058379       rs779226607       rs779242361       rs779255686       rs779440956       rs779522728       rs779637163       rs779988341       rs780001062       rs780108082       rs780185256       rs780309230       rs780446360       rs780862207       rs781138659       rs781620258       rs781779075      

基因表达

基因表达

KLK11基因在不同组织中的表达：    [UniProt]

基因在不同组织中的表达图

基因引物

基因引物

正向引物序列
正向引物Tm值
反向引物序列
反向引物Tm值
rank
AGACCAGGATCATCAAGGG
58
TGAACTATGTAGCGGCCAC
59
TTAATCCTGCTTGCTCTGG
57
AATGATGGTGATGTTGGCG
58
TTAATCCTGCTTGCTCTGG
57
CAATGATGGTGATGTTGGC
57
GTTAATCCTGCTTGCTCTGG
59
AATGATGGTGATGTTGGCG
58
GAGACCAGGATCATCAAGGG
59
GTGAACTATGTAGCGGCCA
59
CAACATCACAGACACCATGG
59
GAGATAATGCCTTGAAGAGACTG
59
GCAGTTAATCCTGCTTGCT
58
CCTTGATGATCCTGGTCTC
57
AAGTGTGAGAACGCCTACC
59
CTTGAAGAGACTGGCAGGA
59
AGTTAATCCTGCTTGCTCTG
58
CCCTTGATGATCCTGGTCTC
59
AAGTGTGAGAACGCCTACC
59
TTGAAGAGACTGGCAGGAG
59

转录因子

转录因子

      尚未收录相关数据

基因本体信息

KLK11基因（以及对应的蛋白质）的细胞分布位置：

[UniProt]     [GenomeNet]

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • 溶酶体
  • 内涵体
  • 细胞核
  • 细胞质
  • 液泡
  • 细胞膜
  • 细胞外基质
  • 内质网
  • 线粒体
  • 高尔基体
  • 细胞骨架

KLK11基因的本体（GO）信息：

GO库代码
对应的蛋白质
来源代码
GO:0004252
A0A0A0MR55(UniProtKB)
IEA
GO:0006508
A0A0A0MR55(UniProtKB)
IEA
GO:0004252
M0QYW4(UniProtKB)
IEA
GO:0006508
M0QYW4(UniProtKB)
IEA
GO:0004252
M0QZI8(UniProtKB)
IEA
GO:0006508
M0QZI8(UniProtKB)
IEA
GO:0004252
M0QZV0(UniProtKB)
IEA
GO:0006508
M0QZV0(UniProtKB)
IEA
GO:0004252
M0R151(UniProtKB)
IEA
GO:0006508
M0R151(UniProtKB)
IEA
GO:0004252
Q9UBX7(UniProtKB)
IEA
GO:0005615
Q9UBX7(UniProtKB)
IDA
GO:0005794
Q9UBX7(UniProtKB)
IEA
GO:0006508
Q9UBX7(UniProtKB)
IEA
GO:0008236
Q9UBX7(UniProtKB)
TAS
GO:0070062
Q9UBX7(UniProtKB)
IDA

基因相互作用关系

基因相互作用关系

基因与其他基因之间的相互作用关系图
序号 作用方式 资源库来源/分值 基因名称 基因名称

基因相关microRNA

基因相关microRNA

可能调控KLK11基因的相关microRNA：     

基因通路图

基因通路图

基因的通路属性图
通路基因列表

基因相关疾病

基因相关疾病

疾病名称 关系值 NofPmids NofSnps 来源
疾病名称 关系值 NofPmids NofSnps 来源
ovarian neoplasm 0.008444493 3 0 BeFree_LHGDN
Prostatic Neoplasms 0.008173051 3 0 LHGDN
Malignant neoplasm of prostate 0.004538567 9 0 BeFree_GAD
Ovarian Carcinoma 0.003181358 4 0 BeFree_GAD
Epithelial ovarian cancer 0.002909916 3 0 BeFree_GAD
Mammary Neoplasms 0.00272435 1 0 LHGDN
Prostatic Hyperplasia 0.00272435 1 0 LHGDN
Prostate carcinoma 0.002171535 8 0 BeFree
Malignant neoplasm of breast 0.001085767 4 0 BeFree
Breast Carcinoma 0.000814326 3 0 BeFree
Non-Small Cell Lung Carcinoma 0.000542884 2 0 BeFree
Malignant neoplasm of ovary 0.000542884 2 0 BeFree
Adenoma 0.000271442 1 0 BeFree
Renal Cell Carcinoma 0.000271442 1 0 BeFree
Colorectal Neoplasms 0.000271442 1 0 BeFree
Malignant neoplasm of stomach 0.000271442 1 0 BeFree
Mesothelioma 0.000271442 1 0 BeFree
Neoplasm Metastasis 0.000271442 1 0 BeFree
Psoriasis 0.000271442 1 0 BeFree
Laryngeal Squamous Cell Carcinoma 0.000271442 1 0 BeFree
Stomach Carcinoma 0.000271442 1 0 BeFree
Adenocarcinoma of large intestine 0.000271442 1 0 BeFree
Benign Prostatic Hyperplasia 0.000271442 1 0 BeFree

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