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This gene is the putative transforming gene of avian sarcoma virus 17. It encodes a protein which is highly similar to the viral protein, and which interacts directly with specific target DNA sequences to regulate gene expression. This gene is intronless and is mapped to 1p32-p31, a chromosomal region involved in both translocations and deletions in human malignancies. [provided by RefSeq, Jul 2008]
[中文简述(自动翻译):]  该基因是鸟肉瘤病毒17的推定的转化基因它编码一蛋白,其是高度相似的病毒蛋白,并直接与特定靶DNA序列相互作用,以调节基因表达。这种基因是无内含子并且被映射到1p32-P31,涉及在人类恶性肿瘤都易位和缺失的染色体区域。 [由RefSeq的,2008年7月提供]
JUN基因(以及对应的蛋白质)的细胞分布位置:
JUN基因的本体(GO)信息:
疾病名称 | 关系值 | NofPmids | NofSnps | 来源 |
Mammary Neoplasms | 0.134164635 | 8 | 0 | BeFree_CTD_human_LHGDN |
Liver carcinoma | 0.128434561 | 13 | 0 | BeFree_CTD_human_LHGDN |
Osteosarcoma | 0.125720142 | 4 | 0 | BeFree_CTD_human_LHGDN |
Stomach Neoplasms | 0.1254487 | 3 | 0 | CTD_human_LHGDN |
Colonic Neoplasms | 0.12272435 | 3 | 0 | CTD_human_LHGDN |
Lung Neoplasms | 0.12272435 | 2 | 0 | CTD_human_LHGDN |
Liver neoplasms | 0.121085767 | 6 | 0 | BeFree_CTD_human |
Neoplastic Cell Transformation | 0.12 | 1 | 0 | CTD_human |
Brain Ischemia | 0.12 | 1 | 0 | CTD_human |
Heat Stroke | 0.12 | 1 | 0 | CTD_human |
Hemangiosarcoma | 0.12 | 1 | 0 | CTD_human |
Intestinal Polyps | 0.12 | 1 | 0 | CTD_human |
Peripheral Neuropathy | 0.12 | 2 | 0 | CTD_human |
Reperfusion Injury | 0.12 | 1 | 0 | CTD_human |
Status Epilepticus | 0.12 | 1 | 0 | CTD_human |
Mercury Poisoning, Nervous System | 0.12 | 1 | 0 | CTD_human |
Juvenile arthritis | 0.12 | 1 | 0 | CTD_human |
Hypertensive disease | 0.080271442 | 2 | 0 | BeFree_RGD |
Depressive disorder | 0.08 | 1 | 0 | RGD |
Kidney Neoplasm | 0.08 | 1 | 0 | RGD |
PULMONARY DISEASE, CHRONIC OBSTRUCTIVE, SEVERE EARLY-ONSET | 0.08 | 0 | 0 | MGD |
Emphysema, Hereditary Pulmonary | 0.08 | 0 | 0 | MGD |
Prostatic Neoplasms | 0.010897401 | 4 | 0 | LHGDN |
Carcinogenesis | 0.007871814 | 29 | 0 | BeFree |
Malignant neoplasm of breast | 0.007252986 | 19 | 0 | BeFree_GAD |
Neoplasm Metastasis | 0.007077352 | 8 | 0 | BeFree_LHGDN |
Adenocarcinoma | 0.0054487 | 2 | 0 | LHGDN |
Anoxia | 0.0054487 | 2 | 0 | LHGDN |
Hodgkin Disease | 0.0054487 | 2 | 0 | LHGDN |
Pancreatic Neoplasm | 0.0054487 | 2 | 0 | LHGDN |
Breast Carcinoma | 0.00434307 | 16 | 0 | BeFree |
Rheumatoid Arthritis | 0.003810118 | 5 | 0 | BeFree_LHGDN |
Lupus Erythematosus, Systemic | 0.003810118 | 5 | 0 | BeFree_LHGDN |
Lymphoma | 0.003538676 | 4 | 0 | BeFree_LHGDN |
Psoriasis | 0.003538676 | 4 | 0 | BeFree_LHGDN |
Myeloid Leukemia | 0.003267234 | 3 | 0 | BeFree_LHGDN |
Glioma | 0.002995792 | 2 | 0 | BeFree_LHGDN |
Pulmonary Hypertension | 0.002995792 | 2 | 0 | BeFree_LHGDN |
Lymphoma, T-Cell, Cutaneous | 0.002995792 | 1 | 0 | BeFree_LHGDN |
Polycystic Kidney, Autosomal Dominant | 0.002995792 | 2 | 0 | BeFree_LHGDN |
Colorectal Cancer | 0.002985861 | 11 | 0 | BeFree |
Malignant neoplasm of ovary | 0.002909916 | 3 | 0 | BeFree_GAD |
Diabetic Nephropathy | 0.00272435 | 1 | 0 | LHGDN |
Endometrial Neoplasms | 0.00272435 | 1 | 0 | LHGDN |
Hepatitis | 0.00272435 | 1 | 0 | LHGDN |
Hyperoxia | 0.00272435 | 1 | 0 | LHGDN |
melanoma | 0.002714419 | 10 | 0 | BeFree |
Prostate carcinoma | 0.002714419 | 10 | 0 | BeFree |
Crohn Disease | 0.002638474 | 2 | 0 | BeFree_GAD |
Colorectal Carcinoma | 0.002442977 | 9 | 0 | BeFree |
Campylobacter infection | 0.002367032 | 1 | 0 | GAD |
Salmonella infections | 0.002367032 | 1 | 0 | GAD |
Arthritis, Reactive | 0.002367032 | 1 | 0 | GAD |
Malignant neoplasm of prostate | 0.002171535 | 8 | 0 | BeFree |
Colon Carcinoma | 0.001900093 | 7 | 0 | BeFree |
Stomach Carcinoma | 0.001900093 | 7 | 0 | BeFree |
Asthma | 0.001628651 | 6 | 0 | BeFree |
Malignant tumor of colon | 0.001628651 | 6 | 0 | BeFree |
Adult T-Cell Lymphoma/Leukemia | 0.001628651 | 6 | 0 | BeFree |
Malignant neoplasm of stomach | 0.001357209 | 5 | 0 | BeFree |
Cervix carcinoma | 0.001357209 | 5 | 0 | BeFree |
Tumor Promotion | 0.001357209 | 5 | 0 | BeFree |
Squamous cell carcinoma | 0.001085767 | 4 | 0 | BeFree |
Malignant tumor of cervix | 0.001085767 | 4 | 0 | BeFree |
Ovarian Carcinoma | 0.001085767 | 4 | 0 | BeFree |
Pancreatic carcinoma | 0.001085767 | 4 | 0 | BeFree |
Malignant neoplasm of pancreas | 0.001085767 | 4 | 0 | BeFree |
Malignant neoplasm of urinary bladder | 0.000814326 | 3 | 0 | BeFree |
Non-Small Cell Lung Carcinoma | 0.000814326 | 3 | 0 | BeFree |
Dermatitis, Atopic | 0.000814326 | 3 | 0 | BeFree |
Eczema | 0.000814326 | 3 | 0 | BeFree |
Glioblastoma | 0.000814326 | 3 | 0 | BeFree |
Leukemia, T-Cell | 0.000814326 | 3 | 0 | BeFree |
Neuroblastoma | 0.000814326 | 3 | 0 | BeFree |
Virus Diseases | 0.000814326 | 3 | 0 | BeFree |
Tumor Progression | 0.000814326 | 3 | 0 | BeFree |
Ki-1+ Anaplastic Large Cell Lymphoma | 0.000814326 | 3 | 0 | BeFree |
Malignant neoplasm of lung | 0.000814326 | 3 | 0 | BeFree |
Carcinoma of lung | 0.000814326 | 3 | 0 | BeFree |
Carcinoma of bladder | 0.000814326 | 3 | 0 | BeFree |
Central neuroblastoma | 0.000814326 | 3 | 0 | BeFree |
Nasopharyngeal carcinoma | 0.000814326 | 3 | 0 | BeFree |
Arthritis | 0.000542884 | 2 | 0 | BeFree |
Bronchiolitis | 0.000542884 | 2 | 4 | BeFree |
Condylomata Acuminata | 0.000542884 | 2 | 0 | BeFree |
Fibrosarcoma | 0.000542884 | 2 | 0 | BeFree |
HIV Infections | 0.000542884 | 2 | 0 | BeFree |
leukemia | 0.000542884 | 2 | 0 | BeFree |
liposarcoma | 0.000542884 | 2 | 0 | BeFree |
Lyme Disease | 0.000542884 | 2 | 0 | BeFree |
Multiple Myeloma | 0.000542884 | 2 | 0 | BeFree |
polyps | 0.000542884 | 2 | 0 | BeFree |
Schizophrenia | 0.000542884 | 2 | 0 | BeFree |
Systemic Scleroderma | 0.000542884 | 2 | 0 | BeFree |
Septicemia | 0.000542884 | 2 | 0 | BeFree |
Liposarcoma, Dedifferentiated | 0.000542884 | 2 | 0 | BeFree |
Sepsis | 0.000542884 | 2 | 0 | BeFree |
Helicobacter pylori (H. pylori) infection in conditions classified elsewhere and of unspecified site | 0.000542884 | 2 | 0 | BeFree |
Thyroid carcinoma | 0.000542884 | 2 | 0 | BeFree |
Helicobacter pylori infection | 0.000542884 | 2 | 0 | BeFree |
Squamous cell carcinoma of the head and neck | 0.000542884 | 2 | 0 | BeFree |
Tumor Angiogenesis | 0.000542884 | 2 | 0 | BeFree |
Alzheimer's Disease | 0.000271442 | 1 | 0 | BeFree |
Anaplasia | 0.000271442 | 1 | 0 | BeFree |
Anemia, Sickle Cell | 0.000271442 | 1 | 0 | BeFree |
Aortic Aneurysm | 0.000271442 | 1 | 0 | BeFree |
Aortic Valve Stenosis | 0.000271442 | 1 | 0 | BeFree |
Brain Diseases | 0.000271442 | 1 | 0 | BeFree |
Candidiasis | 0.000271442 | 1 | 0 | BeFree |
Carcinoid Tumor | 0.000271442 | 1 | 0 | BeFree |
Malignant neoplasm of skin | 0.000271442 | 1 | 0 | BeFree |
Malignant neoplasm of thyroid | 0.000271442 | 1 | 0 | BeFree |
Renal Cell Carcinoma | 0.000271442 | 1 | 0 | BeFree |
Cardiovascular Diseases | 0.000271442 | 1 | 0 | BeFree |
Cerebral Infarction | 0.000271442 | 1 | 0 | BeFree |
Congenital chromosomal disease | 0.000271442 | 1 | 0 | BeFree |
Cystic Fibrosis | 0.000271442 | 1 | 0 | BeFree |
Dermatitis | 0.000271442 | 1 | 0 | BeFree |
Eclampsia | 0.000271442 | 1 | 0 | BeFree |
Enteritis | 0.000271442 | 1 | 0 | BeFree |
Gastritis | 0.000271442 | 1 | 0 | BeFree |
Gastroesophageal reflux disease | 0.000271442 | 1 | 0 | BeFree |
Glomerulonephritis | 0.000271442 | 1 | 0 | BeFree |
Cardiac Arrest | 0.000271442 | 1 | 0 | BeFree |
Hyperglycemia | 0.000271442 | 1 | 0 | BeFree |
Polycystic Kidney Diseases | 0.000271442 | 1 | 0 | BeFree |
Acute lymphocytic leukemia | 0.000271442 | 1 | 0 | BeFree |
Leukemia, Myelocytic, Acute | 0.000271442 | 1 | 0 | BeFree |
Liver diseases | 0.000271442 | 1 | 0 | BeFree |
Lung diseases | 0.000271442 | 1 | 0 | BeFree |
Monoclonal Gammopathy of Undetermined Significance | 0.000271442 | 1 | 0 | BeFree |
Obesity | 0.000271442 | 1 | 0 | BeFree |
Ocular Hypertension | 0.000271442 | 1 | 0 | BeFree |
Degenerative polyarthritis | 0.000271442 | 1 | 0 | BeFree |
Pneumonia | 0.000271442 | 1 | 0 | BeFree |
Pseudomyxoma Peritonei | 0.000271442 | 1 | 0 | BeFree |
Pulmonary Emphysema | 0.000271442 | 1 | 0 | BeFree |
Respiratory Syncytial Virus Infections | 0.000271442 | 1 | 0 | BeFree |
Rotavirus Infections | 0.000271442 | 1 | 0 | BeFree |
Sarcoidosis | 0.000271442 | 1 | 0 | BeFree |
Scrub Typhus | 0.000271442 | 1 | 0 | BeFree |
Thyroid Diseases | 0.000271442 | 1 | 0 | BeFree |
Unipolar Depression | 0.000271442 | 1 | 0 | BeFree |
Vascular Diseases | 0.000271442 | 1 | 0 | BeFree |
Diffuse Large B-Cell Lymphoma | 0.000271442 | 1 | 0 | BeFree |
Small cell carcinoma of lung | 0.000271442 | 1 | 0 | BeFree |
Adenocarcinoma of lung (disorder) | 0.000271442 | 1 | 0 | BeFree |
Medullary carcinoma of thyroid | 0.000271442 | 1 | 0 | BeFree |
Severe myopia | 0.000271442 | 1 | 0 | BeFree |
Erythroblastosis | 0.000271442 | 1 | 0 | BeFree |
Cancer of Head and Neck | 0.000271442 | 1 | 0 | BeFree |
Condyloma | 0.000271442 | 1 | 0 | BeFree |
Restenosis | 0.000271442 | 1 | 0 | BeFree |
Carcinoid tumor no ICD-O subtype | 0.000271442 | 1 | 0 | BeFree |
Adenocarcinoma of colon | 0.000271442 | 1 | 0 | BeFree |
Non-alcoholic Fatty Liver Disease | 0.000271442 | 1 | 0 | BeFree |
Idiopathic crescentic glomerulonephritis | 0.000271442 | 1 | 0 | BeFree |
Epithelial ovarian cancer | 0.000271442 | 1 | 0 | BeFree |
Secondary malignant neoplasm of lymph node | 0.000271442 | 1 | 0 | BeFree |
Invasive breast carcinoma | 0.000271442 | 1 | 0 | BeFree |
Cerebral Ischemia | 0.000271442 | 1 | 0 | BeFree |
ovarian neoplasm | 0.000271442 | 1 | 0 | BeFree |
Sarcoma | 0.000271442 | 1 | 0 | BeFree |
Major Depressive Disorder | 0.000271442 | 1 | 0 | BeFree |
Hepatocarcinogenesis | 0.000271442 | 1 | 0 | BeFree |
Glucocorticoid Receptor Deficiency | 0.000271442 | 1 | 0 | BeFree |
Corneal dystrophy, Fuchs' endothelial, 1 | 0.000271442 | 1 | 0 | BeFree |
Precursor Cell Lymphoblastic Leukemia Lymphoma | 0.000271442 | 1 | 0 | BeFree |
Oropharyngeal Carcinoma | 0.000271442 | 1 | 0 | BeFree |
AORTIC VALVE DISEASE 2 | 0.000271442 | 1 | 0 | BeFree |
Intellectual Disability | 0.000271442 | 1 | 0 | BeFree |
Experimental Organism Basal Cell Carcinoma | 0.000271442 | 1 | 0 | BeFree |
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