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The protein encoded by this gene belongs to the class II cytokine receptor family, and has been shown to be a receptor for interleukin 22 (IL22). IL22 receptor is a protein complex that consists of this protein and interleukin 10 receptor, beta (IL10BR/CRFB4), a subunit also shared by the receptor complex for interleukin 10 (IL10). This gene and interleukin 28 receptor, alpha (IL28RA) form a cytokine receptor gene cluster in the chromosomal region 1p36. [provided by RefSeq, Jul 2008]
[中文简述(自动翻译):]  由该基因编码的蛋白质属于II类细胞因子受体家族,并已被证明是对白细胞介素22(IL22)的受体。 IL22受体是一种蛋白质复合物,由这种蛋白和白细胞介素10受体β(IL10BR / CRFB4),一个亚基也被受体复合物白细胞介素10(IL10)的共享。这个基因,白细胞介素28受体,α(IL28RA)以在染色体区域1p36细胞因子受体基因簇。 [由RefSeq的,2008年7月提供]
IL22RA1基因(以及对应的蛋白质)的细胞分布位置:
IL22RA1基因的本体(GO)信息:
| 疾病名称 | 关系值 | NofPmids | NofSnps | 来源 |
| Nasal Polyps | 0.003538676 | 3 | 0 | BeFree_LHGDN |
| Rhinitis | 0.002367032 | 1 | 0 | GAD |
| Sinusitis | 0.002367032 | 1 | 0 | GAD |
| Chronic sinusitis | 0.000542884 | 2 | 0 | BeFree |
| Psoriasis | 0.000271442 | 1 | 0 | BeFree |
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