IL13基因详情-基因数据库-基因云馆

IL13(interleukin 13)

基因简称(symbol)

IL13 [HGNC] [GeneCards] [NCBI]

基因种类(locus group)

protein-coding gene

同源简称(alias symbol)

P600|IL-13|ALRH|BHR1|MGC116786|MGC116788|MGC116789

基因家族代码(gene_family_id)

601 [HGNC] [GenScript]

omim代码

147683

entrez码

3596 [Vega]

vega基因码

OTTHUMG00000059723

ensembl基因码

ENSG00000169194 [Ensembl]

基因家族(gene family)

Interleukins

refseq数据库代号

NM_002188

更多...

基因种类(locus_type)

gene with protein product

基因名称状态(status)

Approved

location_sortable

05q31

同源基因名称(alias name)

allergic rhinitis|Bronchial hyperresponsiveness-1 (bronchial asthma)

基因名称批准使用时间(date_approved_reserved)

1993-04-07T00:00:00Z

基因简称更名时间(date_symbol_changed)

基因名称更名时间(date_name_changed)

更新时间(date_modified)

2014-11-19T00:00:00Z

ucsc码

uc003kxj.1

ena

U31120

ccds数据码

CCDS4157

uniprot数据码

P35225

pubmed代码

mgd码

MGI:96541

rgd码

RGD:68949

生命科学数据库(lsdb)

更新时间(date modified)

2014-11-19T00:00:00Z

cosmic

IL13

mirbase

基因曾用简称(prev symbol)

基因曾用名称(prev name)

homeodb

cosmic

IL13

snornabase

bioparadigms slc

orphanet

假基因信息(pseudogeneorg)

horde id

merops

imgt

iuphar

kznf基因类别

mamit-trnadb

cd

LncRNA数据库

酶代码

中间纤维数据库

收起

5q31

This gene encodes an immunoregulatory cytokine produced primarily by activated Th2 cells. This cytokine is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL4. [provided by RefSeq, Jul 2008]

[中文简述(自动翻译):] 该基因编码主要由活化的Th2细胞产生的免疫调节细胞因子。这种细胞因子参与B细胞的成熟和分化的几个阶段。它上调CD23和MHC II类的表达，并促进B细胞的IgE同种型转换。这种细胞因子下调巨噬细胞活性，从而抑制促炎细胞因子和趋化因子。该细胞因子被发现是对过敏原诱导的哮喘的发病关键的，但通过独立IgE和嗜酸性粒细胞的机制进行操作。这种基因，IL3，IL5，IL4和CSF2形成染色体5q的细胞因子基因簇，这个基因特别接近IL4。 [由RefSeq的，2008年7月提供]

OMIM数据库中对IL13基因的介绍 Wikipedia数据库中对IL13基因的介绍

IL13基因的碱基序列：[NCBI]

IL13基因的碱基突变：显示全部snp

rs847 rs848 rs20541 rs1295685 rs1295686 rs1295687 rs1800925 rs1881457 rs2066960 rs2069738 rs2069739 rs2069740 rs2069741 rs2069742 rs2069743 rs2069744 rs2069745 rs2069746 rs2069747 rs2069748 rs2069749 rs2069750 rs2069755 rs2069756 rs3212142 rs3212145 rs11575055 rs34255686 rs34654684 rs35641705 rs55650044 rs55733734 rs56097948 rs56398553 rs71583493 rs73261671 rs74691474

rs76466995 rs78181870 rs78628956 rs111692618 rs111743543 rs112070175 rs112360340 rs112896241 rs113533223 rs114654496 rs115008099 rs115325936 rs116240019 rs138637232 rs138680496 rs140196099 rs140300006 rs140369292 rs140828306 rs143032763 rs143149119 rs143660447 rs146770163 rs147042457 rs148077750 rs148621685 rs149852100 rs150177673 rs150226731 rs181825588 rs181985600 rs182349015 rs182411589 rs183009956 rs183299996 rs183533990 rs183974496 rs184838848 rs184944562 rs185122731 rs185375084 rs186481753 rs187894831 rs188495193 rs189329440 rs189751596 rs189878912 rs190132828 rs190222211 rs191776887 rs191779987 rs192565440 rs192837804 rs199513811 rs199797009 rs199845178 rs199869056 rs199924106 rs199969967 rs200113399 rs200155765 rs200168712 rs200186367 rs200196698 rs200247901 rs200375404 rs200571678 rs200581554 rs200638839 rs200726947 rs200852476 rs200913948 rs201121980 rs201172066 rs201181769 rs201424420 rs201469726 rs201475069 rs201716976 rs201723465 rs201744269 rs201804555 rs201878455 rs201923060 rs202009492 rs202011628 rs202047364 rs202050622 rs202101165 rs202220644 rs367898110 rs368320626 rs370110665 rs371914367 rs374069088 rs374535004 rs375653129 rs375964270 rs376384925 rs376870298 rs527319875 rs528218309 rs528784778 rs529456706 rs531039668 rs531513937 rs532344450 rs532383493 rs533560009 rs533616846 rs534804182 rs535514412 rs536445464 rs536555115 rs537229075 rs538110009 rs538901488 rs538935527 rs540617089 rs540769520 rs540879242 rs542531549 rs544862168 rs544996676 rs545161562 rs545251005 rs545337063 rs546023282 rs548980829 rs549226361 rs549657365 rs551447208 rs551488083 rs552103568 rs552473475 rs553157729 rs553444004 rs554174789 rs554683418 rs556618159 rs557011098 rs557143804 rs558720033 rs558907104 rs559233831 rs559359129 rs560547280 rs560993434 rs561270872 rs561356790 rs561508196 rs563477414 rs564677020 rs564856494 rs564965877 rs565293175 rs565434733 rs565778458 rs566039790 rs566642920 rs566756777 rs567629873 rs568623867 rs569385458 rs570083916 rs571701686 rs572833910 rs573062442 rs573586397 rs573709804 rs574206329 rs574210453 rs575312971 rs575619943 rs575861246 rs577463465 rs745694958 rs745785960 rs746179303 rs746245700 rs746751863 rs746947963 rs747026798 rs747799114 rs748739561 rs748829533 rs749795771 rs750926575 rs751214731 rs751745832 rs752168427 rs752977001 rs753892265 rs754514806 rs754520718 rs754964536 rs755393562 rs756326109 rs756707941 rs756919832 rs757019938 rs757139512 rs757510998 rs757742023 rs758258492 rs758908496 rs758955797 rs759548576 rs760436499 rs761274909 rs762306581 rs762414781 rs762983915 rs763882844 rs764149458 rs765230043 rs765294353 rs765719901 rs767198237 rs767987922 rs768184182 rs768364050 rs769087732 rs769152159 rs769401124 rs770108365 rs770488630 rs771297548 rs771386711 rs771833459 rs773364000 rs773714921 rs774429439 rs775360450 rs776578550 rs776876174 rs777431829 rs777533503 rs777911950 rs778560262 rs778748365 rs778963746 rs780099128 rs780405199 rs781226872 rs781754061

IL13基因在不同组织中的表达： [UniProt]

正向引物序列

正向引物Tm值

反向引物序列

反向引物Tm值

rank

TCAACATCACCCAGAACCA

59

TTGATGCTCCATACCATGCT

60

TGGTATGGAGCATCAACCTG

60

TTGATCAGGGATTCCAGGG

59

GTCAACATCACCCAGAACC

59

TGATGCTCCATACCATGCT

59

GAAGACCCAGAGGATGCTG

60

TTTCGAAGTTGTTGAACTGTCC

60

GTATGGAGCATCAACCTGAC

59

CGTTGATCAGGGATTCCAG

58

GTCAACATCACCCAGAACC

59

TGATGCTCCATACCATGCT

59

TCAACATCACCCAGAACCA

59

TTGATGCTCCATACCATGCT

60

GAGAAGACCCAGAGGATGC

60

TTCGAAGTTGTTGAACTGTCC

59

TGGTATGGAGCATCAACCT

58

TTGATCAGGGATTCCAGGG

59

TGGTATGGAGCATCAACCT

58

TTGATCAGGGATTCCAGGG

59

尚未收录相关数据

IL13基因（以及对应的蛋白质）的细胞分布位置：

[UniProt] [GenomeNet]

溶酶体
内涵体
细胞核
细胞质
液泡
细胞膜
细胞外基质
内质网
线粒体
高尔基体
细胞骨架

IL13基因的本体（GO）信息：

GO库代码

对应的蛋白质

来源代码

GO:0005126

A0A087WW07(UniProtKB)

IEA

GO:0005576

A0A087WW07(UniProtKB)

IEA

GO:0006955

A0A087WW07(UniProtKB)

IEA

GO:0001774

P35225(UniProtKB)

IEA

GO:0002639

P35225(UniProtKB)

IBA

GO:0005125

P35225(UniProtKB)

IEA

GO:0005144

P35225(UniProtKB)

IBA

GO:0005515

P35225(UniProtKB)

IPI

GO:0005576

P35225(UniProtKB)

IDA

GO:0005576

P35225(UniProtKB)

TAS

GO:0005615

P35225(UniProtKB)

IBA

GO:0005615

P35225(UniProtKB)

ISS

GO:0005737

P35225(UniProtKB)

IEA

GO:0006928

P35225(UniProtKB)

TAS

GO:0006954

P35225(UniProtKB)

IEA

GO:0006955

P35225(UniProtKB)

IEA

GO:0007165

P35225(UniProtKB)

NAS

GO:0007267

P35225(UniProtKB)

IC

GO:0009897

P35225(UniProtKB)

IEA

GO:0010155

P35225(UniProtKB)

IEA

GO:0030890

P35225(UniProtKB)

IBA

GO:0032496

P35225(UniProtKB)

IEA

GO:0032723

P35225(UniProtKB)

IEA

GO:0033861

P35225(UniProtKB)

IEA

GO:0035094

P35225(UniProtKB)

IEA

GO:0042526

P35225(UniProtKB)

IEA

GO:0043032

P35225(UniProtKB)

IBA

GO:0043306

P35225(UniProtKB)

IBA

GO:0045471

P35225(UniProtKB)

IEA

GO:0048661

P35225(UniProtKB)

IEA

GO:0050714

P35225(UniProtKB)

IEA

GO:0051281

P35225(UniProtKB)

IEA

GO:0071260

P35225(UniProtKB)

IEA

GO:0071345

P35225(UniProtKB)

IBA

GO:0071635

P35225(UniProtKB)

IEA

GO:1901215

P35225(UniProtKB)

IEA

GO:1901247

P35225(UniProtKB)

NAS

GO:1901251

P35225(UniProtKB)

NAS

GO:1903660

P35225(UniProtKB)

IMP

GO:2000231

P35225(UniProtKB)

IEA

GO:2000352

P35225(UniProtKB)

IMP

序号	作用方式	资源库来源/分值	基因名称	基因名称

可能调控IL13基因的相关microRNA：

hsa-let-7a hsa-let-7b hsa-let-7b* hsa-let-7c hsa-let-7c* hsa-let-7d hsa-let-7d* hsa-let-7e hsa-let-7e* hsa-let-7f hsa-let-7g hsa-let-7g* hsa-let-7i hsa-let-7i* hsa-miR-21* hsa-miR-98

通路基因列表

疾病名称

关系值

NofPmids

NofSnps

来源

疾病名称	关系值	NofPmids	NofSnps	来源
Asthma	0.490519253	233	7	BeFree_CTD_human_GAD_GWASCAT_LHGDN_RGD
Dermatitis, Atopic	0.343136029	44	1	BeFree_CTD_human_GAD_GWASCAT_LHGDN_MGD
Psoriasis	0.250715717	14	3	BeFree_CTD_human_GAD_GWASCAT_LHGDN
Pulmonary Fibrosis	0.200814326	5	0	BeFree_CTD_human_RGD
Arthritis, Experimental	0.2	2	0	CTD_human_RGD
Inflammation	0.141660606	10	0	CTD_human_GAD_LHGDN
Allergic rhinitis (disorder)	0.133420204	32	2	BeFree_CTD_human_GAD
Hodgkin Disease	0.129901391	12	3	BeFree_GAD_GWASCAT_LHGDN
Immediate hypersensitivity	0.129468128	6	0	CTD_human_GAD
Bronchial Hyperreactivity	0.128815624	9	0	BeFree_CTD_human_GAD_LHGDN
Hypersensitivity	0.127101096	4	0	CTD_human_GAD
Pneumonia	0.124624443	9	0	BeFree_CTD_human_LHGDN
Hyperplasia	0.12272435	2	0	CTD_human_LHGDN
Renal Cell Carcinoma	0.121357209	5	0	BeFree_CTD_human
Lung diseases	0.120542884	3	0	BeFree_CTD_human
Autistic Disorder	0.12	1	0	CTD_human
Drug Allergy	0.12	1	0	CTD_human
Metaplasia	0.12	1	0	CTD_human
Sinusitis	0.12	1	0	CTD_human
Hepatitis, Autoimmune	0.12	1	0	CTD_human
ASTHMA, SUSCEPTIBILITY TO (finding)	0.12	0	1	CLINVAR
Rhinitis	0.091268532	6	0	BeFree_GAD_LHGDN_RGD
Fibrosis	0.090897401	5	0	LHGDN_RGD
Schistosomiasis mansoni	0.088087174	5	0	BeFree_GAD_LHGDN_RGD
Sepsis	0.082367032	2	0	GAD_RGD
Pulmonary Hypertension	0.080271442	2	0	BeFree_RGD
Lipoid nephrosis	0.080271442	2	0	BeFree_RGD
Extrinsic allergic alveolitis	0.08	1	0	RGD
Peptic Esophagitis	0.08	1	0	RGD
Hepatitis, Alcoholic	0.08	1	0	RGD
Lung Diseases, Fungal	0.08	1	0	RGD
Pancreatitis	0.08	1	0	RGD
Reperfusion Injury	0.08	1	0	RGD
Acute Lung Injury	0.08	1	0	RGD
Infarction, Middle Cerebral Artery	0.08	1	0	RGD
Prostatic Hyperplasia	0.08	1	0	RGD
Chronic Obstructive Airway Disease	0.028728026	22	0	BeFree_GAD_LHGDN
Atopy	0.021303288	9	0	GAD
Infection	0.013264433	5	0	GAD_LHGDN
Allergic asthma	0.012334436	28	0	BeFree_GAD
Premature Birth	0.012192478	5	0	GAD_LHGDN
Eczema	0.011400559	42	0	BeFree
Graves Disease	0.011368221	9	0	BeFree_GAD
Systemic Scleroderma	0.010258709	10	0	BeFree_GAD_LHGDN
Malignant neoplasm of lung	0.010011012	6	4	BeFree_GAD
Glioblastoma	0.009348576	18	3	BeFree_GAD
Hay fever	0.00764398	5	3	BeFree_GAD
Nephrotic Syndrome	0.00764398	5	0	BeFree_GAD
Glioma	0.007057489	26	5	BeFree
Diabetes Mellitus, Insulin-Dependent	0.006905599	8	0	BeFree_GAD
Respiratory Syncytial Virus Infections	0.006634157	9	0	BeFree_GAD
Allergic disposition	0.006514605	24	0	BeFree
Eosinophilia	0.005624334	13	0	BeFree_GAD
Onchocerciasis	0.005362824	1	0	BeFree_GAD_LHGDN
Schistosoma hematobium infection	0.005362824	3	2	BeFree_GAD_LHGDN
Diabetes Mellitus, Non-Insulin-Dependent	0.005276948	4	0	BeFree_GAD
Malaria, Falciparum	0.005005506	3	2	BeFree_GAD
Ulcerative Colitis	0.004895885	9	0	BeFree_LHGDN
Bronchiolitis, Viral	0.004734064	2	0	GAD
Latex allergy	0.004734064	2	0	GAD
Venous Thromboembolism	0.004734064	2	0	GAD
Brain Neoplasms	0.004538567	9	0	BeFree_GAD
Arthritis, Psoriatic	0.003995683	6	0	BeFree_GAD
Childhood asthma	0.003995683	6	1	BeFree_GAD
Idiopathic Pulmonary Fibrosis	0.003810118	5	1	BeFree_LHGDN
Malignant neoplasm of breast	0.003724241	6	0	BeFree_GAD
Crohn Disease	0.003538676	4	0	BeFree_LHGDN
Degenerative polyarthritis	0.003452799	5	0	BeFree_GAD
Squamous cell carcinoma	0.003267234	3	0	BeFree_LHGDN
Diabetes Mellitus	0.003267234	3	0	BeFree_LHGDN
Eosinophilic disorder	0.003257302	12	0	BeFree
Disorder characterized by eosinophilia	0.003257302	12	0	BeFree
HIV Infections	0.003181358	4	0	BeFree_GAD
Periodontitis, Juvenile	0.003181358	3	0	BeFree_GAD
Graft-vs-Host Disease	0.002995792	2	0	BeFree_LHGDN
Gastritis, Atrophic	0.002909916	2	0	BeFree_GAD
Stevens-Johnson Syndrome	0.002909916	2	0	BeFree_GAD
Adenocarcinoma	0.00272435	1	0	LHGDN
Amyotrophic Lateral Sclerosis	0.00272435	1	0	LHGDN
Esophagitis	0.00272435	1	0	LHGDN
Multiple Organ Failure	0.00272435	1	0	LHGDN
Urticaria	0.00272435	1	0	LHGDN
Eosinophilic esophagitis	0.002714419	10	0	BeFree
Malignant Glioma	0.002714419	10	0	BeFree
Atherosclerosis	0.002638474	2	0	BeFree_GAD
Malignant neoplasm of urinary bladder	0.002638474	2	0	BeFree_GAD
Toxic Epidermal Necrolysis	0.002638474	1	0	BeFree_GAD
Lupus Erythematosus, Systemic	0.002638474	2	0	BeFree_GAD
Multiple Myeloma	0.002638474	2	0	BeFree_GAD
Dermatologic disorders	0.002638474	2	0	BeFree_GAD
Diffuse Large B-Cell Lymphoma	0.002638474	2	0	BeFree_GAD
Malignant neoplasm of brain	0.002638474	2	0	BeFree_GAD
Mastocytosis, Systemic	0.002638474	1	0	BeFree_GAD
Chronic Periodontitis	0.002638474	2	0	BeFree_GAD
Juvenile arthritis	0.002638474	1	0	BeFree_GAD
Respiratory syncytial virus (RSV) infection in conditions classified elsewhere and of unspecified site	0.002442977	9	0	BeFree
Asthma, Exercise-Induced	0.002367032	1	0	GAD
Biliary Tract Neoplasm	0.002367032	1	0	GAD
Chlamydia Infections	0.002367032	1	0	GAD
Conjunctivitis	0.002367032	1	0	GAD
Connective Tissue Diseases	0.002367032	1	0	GAD
Erythema Nodosum	0.002367032	1	0	GAD
Fetal Diseases	0.002367032	1	0	GAD
Food Allergy	0.002367032	1	0	GAD
IGA Glomerulonephritis	0.002367032	1	0	GAD
Hypertensive disease	0.002367032	1	0	GAD
Chronic Lymphocytic Leukemia	0.002367032	1	0	GAD
Musculoskeletal Diseases	0.002367032	1	0	GAD
Peptic Ulcer	0.002367032	1	0	GAD
Pre-Eclampsia	0.002367032	1	0	GAD
Pregnancy Complications	0.002367032	1	0	GAD
Pregnancy Complications, Hematologic	0.002367032	1	0	GAD
Prenatal Exposure Delayed Effects	0.002367032	1	0	GAD
Puerperal Disorders	0.002367032	1	0	GAD
Purpura	0.002367032	1	0	GAD
Sarcoidosis	0.002367032	1	0	GAD
Schistosomiasis japonica	0.002367032	1	0	GAD
Streptococcal Infections	0.002367032	1	0	GAD
Trachoma	0.002367032	1	0	GAD
Tuberculosis	0.002367032	1	0	GAD
Helicobacter Infections	0.002367032	1	0	GAD
Lymphoma, AIDS-Related	0.002367032	1	0	GAD
Central Nervous System Neoplasms	0.002367032	1	0	GAD
Bacterial Vaginosis	0.002367032	1	0	GAD
Small for gestational age (disorder)	0.002367032	1	0	GAD
Intestinal schistosomiasis	0.002367032	1	0	GAD
Parasitemia	0.002367032	1	0	GAD
Idiopathic generalized epilepsy	0.002367032	1	0	GAD
Dermatitis and eczema	0.002367032	1	0	GAD
Allergy to eggs	0.002367032	1	0	GAD
Sjogren's Syndrome	0.002367032	1	0	GAD
Coronary Artery Disease	0.002367032	1	0	GAD
Rheumatoid Arthritis	0.002171535	8	0	BeFree
airway disease	0.001900093	7	0	BeFree
Inflammatory disorder	0.001900093	7	0	BeFree
Glioblastoma Multiforme	0.001900093	7	0	BeFree
Lymphoma	0.001628651	6	0	BeFree
Nasal Polyps	0.001628651	6	0	BeFree
Wheezing	0.001628651	6	2	BeFree
Allergic sensitization	0.001628651	6	3	BeFree
Dermatitis	0.001357209	5	0	BeFree
Diphtheria	0.001357209	5	0	BeFree
Inflammatory Bowel Diseases	0.001357209	5	0	BeFree
Malaria	0.001357209	5	2	BeFree
Pancreatic carcinoma	0.001357209	5	0	BeFree
Breast Carcinoma	0.001357209	5	0	BeFree
Colorectal Carcinoma	0.001085767	4	2	BeFree
Cancer of Head and Neck	0.001085767	4	0	BeFree
Malignant neoplasm of pancreas	0.001085767	4	0	BeFree
Chronic inflammatory disorder	0.001085767	4	0	BeFree
Colorectal Cancer	0.001085767	4	2	BeFree
Idiopathic Interstitial Pneumonias	0.001085767	4	0	BeFree
Helminthiasis	0.000814326	3	0	BeFree
Immunologic Deficiency Syndromes	0.000814326	3	0	BeFree
Leishmaniasis, Cutaneous	0.000814326	3	0	BeFree
Adult T-Cell Lymphoma/Leukemia	0.000814326	3	0	BeFree
Lymphoma, Non-Hodgkin	0.000814326	3	2	BeFree
melanoma	0.000814326	3	0	BeFree
Neoplasm Metastasis	0.000814326	3	0	BeFree
polyps	0.000814326	3	0	BeFree
Pulmonary Eosinophilia	0.000814326	3	0	BeFree
Respiration Disorders	0.000814326	3	0	BeFree
Respiratory Tract Diseases	0.000814326	3	0	BeFree
Schistosomiasis	0.000814326	3	0	BeFree
Thyroid Diseases	0.000814326	3	0	BeFree
Asthmatic pulmonary eosinophilia	0.000814326	3	0	BeFree
Malignant neoplasm of prostate	0.000814326	3	0	BeFree
Carcinogenesis	0.000814326	3	0	BeFree
Prostate carcinoma	0.000814326	3	0	BeFree
Carcinoma of lung	0.000814326	3	4	BeFree
Xenograft Model	0.000814326	3	0	BeFree
Nephrotic Syndrome, Minimal Change	0.000814326	3	0	BeFree
Autoimmune Diseases	0.000542884	2	0	BeFree
Allergic Conjunctivitis	0.000542884	2	0	BeFree
Scleroderma	0.000542884	2	0	BeFree
Diabetes	0.000542884	2	0	BeFree
Head and Neck Neoplasms	0.000542884	2	0	BeFree
Hepatitis B	0.000542884	2	2	BeFree
Huntington Disease	0.000542884	2	2	BeFree
Immune System Diseases	0.000542884	2	0	BeFree
Influenza	0.000542884	2	0	BeFree
Lymphoproliferative Disorders	0.000542884	2	0	BeFree
Mycoses	0.000542884	2	0	BeFree
Ovarian Carcinoma	0.000542884	2	0	BeFree
Pancreatic Neoplasm	0.000542884	2	0	BeFree
Periodontitis	0.000542884	2	0	BeFree
Prostatic Neoplasms	0.000542884	2	0	BeFree
Pulmonary Emphysema	0.000542884	2	0	BeFree
Tetanus	0.000542884	2	0	BeFree
Virus Diseases	0.000542884	2	0	BeFree
B-Cell Lymphomas	0.000542884	2	0	BeFree
Lymphoma, T-Cell, Cutaneous	0.000542884	2	0	BeFree
Chronic sinusitis	0.000542884	2	0	BeFree
Pancreatitis, Chronic	0.000542884	2	0	BeFree
Pneumonia, Interstitial	0.000542884	2	0	BeFree
Solid tumour	0.000542884	2	0	BeFree
allergic symptom	0.000542884	2	0	BeFree
ovarian neoplasm	0.000542884	2	0	BeFree
Arthritis, Collagen-Induced	0.000542884	2	0	BeFree
Squamous cell carcinoma of the head and neck	0.000542884	2	0	BeFree
FRAGILE X TREMOR/ATAXIA SYNDROME	0.000542884	2	0	BeFree
Alopecia Areata	0.000271442	1	0	BeFree
Alzheimer's Disease	0.000271442	1	0	BeFree
Amebiasis	0.000271442	1	0	BeFree
Anthracosis	0.000271442	1	0	BeFree
Arthritis	0.000271442	1	2	BeFree
Arthritis, Adjuvant-Induced	0.000271442	1	0	BeFree
Bladder Exstrophy	0.000271442	1	0	BeFree
Bronchiolitis	0.000271442	1	0	BeFree
Bronchiolitis Obliterans	0.000271442	1	0	BeFree
Cachexia	0.000271442	1	0	BeFree
Rectal Carcinoma	0.000271442	1	0	BeFree
Malignant neoplasm of thyroid	0.000271442	1	0	BeFree
Malignant tumor of cervix	0.000271442	1	0	BeFree
Primary biliary cirrhosis	0.000271442	1	0	BeFree
Colitis	0.000271442	1	0	BeFree
Encephalitis	0.000271442	1	0	BeFree
Experimental Autoimmune Encephalomyelitis	0.000271442	1	0	BeFree
Endometriosis	0.000271442	1	0	BeFree
Epithelial hyperplasia	0.000271442	1	0	BeFree
Esophageal Achalasia	0.000271442	1	0	BeFree
Exophthalmos	0.000271442	1	0	BeFree
Disorder of eye	0.000271442	1	0	BeFree
Filariasis	0.000271442	1	0	BeFree
pathologic fistula	0.000271442	1	0	BeFree
Gastroesophageal reflux disease	0.000271442	1	0	BeFree
Hyperthyroidism	0.000271442	1	0	BeFree
Ileitis	0.000271442	1	0	BeFree
Kidney Diseases	0.000271442	1	0	BeFree
Leishmaniasis	0.000271442	1	0	BeFree
Leprosy	0.000271442	1	0	BeFree
Leukemia, T-Cell	0.000271442	1	0	BeFree
Lung Neoplasms	0.000271442	1	0	BeFree
Malaria, Cerebral	0.000271442	1	0	BeFree
Malignant neoplasm of stomach	0.000271442	1	0	BeFree
Mastocytoma	0.000271442	1	0	BeFree
Mastocytosis	0.000271442	1	0	BeFree
Mastodynia	0.000271442	1	1	BeFree
Measles	0.000271442	1	0	BeFree
Medulloblastoma	0.000271442	1	0	BeFree
Meningioma	0.000271442	1	0	BeFree
Mycosis Fungoides	0.000271442	1	0	BeFree
Myocarditis	0.000271442	1	0	BeFree
Nasal congestion (finding)	0.000271442	1	0	BeFree
Neck Neoplasms	0.000271442	1	0	BeFree
Nematode infections	0.000271442	1	0	BeFree
oligodendroglioma	0.000271442	1	0	BeFree
orbit (eye disorders)	0.000271442	1	0	BeFree
Bullous pemphigoid	0.000271442	1	0	BeFree
Pemphigus Vulgaris	0.000271442	1	0	BeFree
Pruritus	0.000271442	1	0	BeFree
Respiratory Distress Syndrome, Adult	0.000271442	1	0	BeFree
Respiratory Tract Infections	0.000271442	1	0	BeFree
Kaposi Sarcoma	0.000271442	1	0	BeFree
Sezary Syndrome	0.000271442	1	0	BeFree
Ankylosing spondylitis	0.000271442	1	0	BeFree
Thyroid Nodule	0.000271442	1	0	BeFree
Tongue Neoplasms	0.000271442	1	0	BeFree
Ocular Toxoplasmosis	0.000271442	1	0	BeFree
Ureteral obstruction	0.000271442	1	0	BeFree
Urticaria Pigmentosa	0.000271442	1	0	BeFree
Vascular Diseases	0.000271442	1	0	BeFree
Intestinal Volvulus	0.000271442	1	0	BeFree
Lymphoma, Large-Cell, Follicular	0.000271442	1	2	BeFree
Spina Bifida	0.000271442	1	0	BeFree
Severe Combined Immunodeficiency	0.000271442	1	0	BeFree
Hamman-Rich syndrome	0.000271442	1	0	BeFree
Idiopathic Membranous Glomerulonephritis	0.000271442	1	0	BeFree
Epstein-Barr Virus Infections	0.000271442	1	0	BeFree
Renal fibrosis	0.000271442	1	0	BeFree
Idiopathic pulmonary hypertension	0.000271442	1	0	BeFree
Hodgkin's disease, nodular sclerosis (clinical)	0.000271442	1	0	BeFree
Malignant neoplasm of testis	0.000271442	1	0	BeFree
Proliferative diabetic retinopathy	0.000271442	1	0	BeFree
Corneal pannus	0.000271442	1	0	BeFree
Intrinsic asthma	0.000271442	1	0	BeFree
Peritoneal adhesion	0.000271442	1	0	BeFree
Right Ventricular Hypertrophy	0.000271442	1	0	BeFree
Autoimmune thyroid disease	0.000271442	1	0	BeFree
Tumor Progression	0.000271442	1	0	BeFree
Cholangiocarcinoma	0.000271442	1	0	BeFree
gliosarcoma	0.000271442	1	0	BeFree
Desquamative interstitial pneumonia	0.000271442	1	0	BeFree
Hand eczema	0.000271442	1	0	BeFree
Psoriasis vulgaris	0.000271442	1	0	BeFree
Asthma, Occupational	0.000271442	1	0	BeFree
Parainfluenza Virus Infections	0.000271442	1	0	BeFree
Cervix carcinoma	0.000271442	1	0	BeFree
Senile Plaques	0.000271442	1	0	BeFree
Pheochromocytoma, malignant	0.000271442	1	0	BeFree
Mast Cell Neoplasm	0.000271442	1	0	BeFree
Thyroid associated opthalmopathies	0.000271442	1	0	BeFree
Seasonal allergic conjunctivitis	0.000271442	1	0	BeFree
Aspirin-sensitive asthma with nasal polyps	0.000271442	1	0	BeFree
Multinodular goiter	0.000271442	1	0	BeFree
Sowda	0.000271442	1	0	BeFree
Steroid-sensitive nephrotic syndrome	0.000271442	1	0	BeFree
Actinic prurigo	0.000271442	1	0	BeFree
Respiratory distress	0.000271442	1	0	BeFree
Secondary malignant neoplasm of liver	0.000271442	1	0	BeFree
Mixed cryoglobulinemia	0.000271442	1	0	BeFree
Deviated nasal septum	0.000271442	1	0	BeFree
Thyroid carcinoma	0.000271442	1	0	BeFree
BREAST PAIN FEMALE	0.000271442	1	1	BeFree
Primary sclerosing cholangitis	0.000271442	1	0	BeFree
Aqueous Humor Disorders	0.000271442	1	0	BeFree
Leukemogenesis	0.000271442	1	0	BeFree
Bacterial sepsis	0.000271442	1	0	BeFree
Stomach Carcinoma	0.000271442	1	0	BeFree
Well Differentiated Oligodendroglioma	0.000271442	1	0	BeFree
Helicobacter pylori infection	0.000271442	1	2	BeFree
Asthma chronic	0.000271442	1	0	BeFree
Polyp of large intestine	0.000271442	1	0	BeFree
Cutaneous Mastocytosis	0.000271442	1	0	BeFree
Malignant neoplasm of ovary	0.000271442	1	0	BeFree
Diffuse Scleroderma	0.000271442	1	0	BeFree
Persistent infection	0.000271442	1	0	BeFree
X-Linked Combined Immunodeficiency Diseases	0.000271442	1	0	BeFree
Nonspecific interstitial pneumonia	0.000271442	1	0	BeFree
Primary Effusion Lymphoma	0.000271442	1	0	BeFree
Mediastinal (Thymic) Large B-Cell Lymphoma	0.000271442	1	0	BeFree
Adenoma of large intestine	0.000271442	1	0	BeFree
Classical Hodgkin's Lymphoma	0.000271442	1	0	BeFree
Pancreatic Ductal Adenocarcinoma	0.000271442	1	0	BeFree
Renal carcinoma	0.000271442	1	0	BeFree
Neonatal necrotizing enterocolitis	0.000271442	1	0	BeFree
Tumor Immunity	0.000271442	1	0	BeFree
Rash and Dermatitis Adverse Event Associated with Chemoradiation	0.000271442	1	0	BeFree
Non-Malignant Ascites Adverse Event	0.000271442	1	0	BeFree
Associated Pulmonary Arterial Hypertension	0.000271442	1	0	BeFree
Glomerulonephritis, Minimal Change	0.000271442	1	0	BeFree
Aggressive periodontitis, generalized	0.000271442	1	0	BeFree
EPIDERMAL DIFFERENTIATION COMPLEX	0.000271442	1	0	BeFree
Syndactyly, Type IV	0.000271442	1	0	BeFree
Liver carcinoma	0.000271442	1	0	BeFree
Benign Mastocytoma	0.000271442	1	0	BeFree
Pulmonary arterial hypertension	0.000271442	1	0	BeFree
Bisphosphonate-associated osteonecrosis	0.000271442	1	0	BeFree
Nonalcoholic Steatohepatitis	0.000271442	1	0	BeFree
Neutrophilia (disorder)	0.000271442	1	0	BeFree
Juvenile rheumatoid arthritis	0.000271442	1	0	BeFree
Pulmonary Hypertension, Primary, 1, With Hereditary Hemorrhagic Telangiectasia	0.000271442	1	0	BeFree