IFI30(interferon, gamma-inducible protein 30)

基因基本信息

基因基本信息

基因简称(symbol)
    [HGNC]     [GeneCards]     [NCBI]
基因种类(locus group)
同源简称(alias symbol)
基因家族代码(gene_family_id)
    [HGNC]     [GenScript]
omim代码
entrez码
    [Vega]
vega基因码
ensembl基因码
    [Ensembl]
基因家族(gene family)
refseq数据库代号

更多...

基因种类(locus_type)
基因名称状态(status)
location_sortable
同源基因名称(alias name)
基因名称批准使用时间(date_approved_reserved)
基因简称更名时间(date_symbol_changed)
基因名称更名时间(date_name_changed)
更新时间(date_modified)
ucsc码
ena
ccds数据码
uniprot数据码
pubmed代码
mgd码
rgd码
生命科学数据库(lsdb)
更新时间(date modified)
cosmic
mirbase
基因曾用简称(prev symbol)
基因曾用名称(prev name)
homeodb
cosmic
snornabase
bioparadigms slc
orphanet
假基因信息(pseudogeneorg)
horde id
merops
imgt
iuphar
kznf基因类别
mamit-trnadb
cd
LncRNA数据库
酶代码
中间纤维数据库

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基因染色体位置

基因染色体位置

19p13.1
基因染色体位置图

基因简述

基因简述

The protein encoded by this gene is a lysosomal thiol reductase that at low pH can reduce protein disulfide bonds. The enzyme is expressed constitutively in antigen-presenting cells and induced by gamma-interferon in other cell types. This enzyme has an important role in MHC class II-restricted antigen processing. [provided by RefSeq, Jul 2008]

[中文简述(自动翻译):]  由该基因编码的蛋白质是溶酶体硫醇还原酶，在低pH值可减少蛋白质二硫键。所述酶在抗原呈递细胞组成型表达并通过在其他细胞类型γ-干扰素诱导。这种酶在MHC II类限制性抗原加工中起重要作用。 [由RefSeq的，2008年7月提供]

OMIM数据库中对IFI30基因的介绍     Wikipedia数据库中对IFI30基因的介绍

基因序列

基因序列

IFI30基因的碱基序列：[NCBI]

基因突变

基因突变

IFI30基因的碱基突变：           显示全部snp
rs2082       rs2921       rs7125       rs15057       rs15953       rs200372       rs200373       rs200374       rs200375       rs200376       rs273262       rs273263       rs273264       rs273265       rs273266       rs273267       rs887945       rs1044862       rs1045747       rs2110576       rs2241089       rs2241090       rs3185630       rs4808118       rs4808756       rs4808757       rs6512247       rs7259445       rs8102682       rs11554159       rs11554160       rs11668950       rs45514694       rs57299686       rs59589815       rs61730355       rs73001407      
rs75239061       rs75821091       rs76227216       rs77198486       rs77583590       rs79557165       rs112207718       rs112504981       rs112609969       rs112712912       rs112973145       rs113288575       rs115266843       rs115575833       rs115607637       rs115658567       rs115948863       rs117005431       rs117257370       rs138269501       rs140154009       rs140704918       rs144149160       rs144758167       rs144767849       rs145545462       rs147448477       rs147477761       rs149650847       rs149723974       rs150456866       rs182095156       rs182494775       rs183685904       rs184164860       rs186549694       rs187137893       rs188393134       rs188878807       rs189125680       rs190670946       rs191513645       rs191901963       rs193024889       rs199599038       rs200444719       rs200448181       rs200549788       rs200628484       rs201205841       rs201952382       rs202043324       rs202128812       rs202191420       rs367697795       rs368357390       rs368484244       rs368679591       rs368682588       rs368871171       rs368965492       rs369048103       rs369094218       rs369152814       rs369176144       rs369260317       rs369358763       rs370041369       rs370349675       rs370440721       rs370455076       rs370566972       rs371344389       rs371536031       rs371677129       rs371845770       rs372016608       rs372458166       rs372940357       rs372953483       rs373154530       rs373433112       rs374435415       rs374934487       rs374971772       rs375083436       rs375252306       rs375461212       rs375674283       rs375751473       rs375989024       rs376122150       rs376296479       rs376499914       rs376719198       rs377500212       rs377732144       rs398040946       rs527525098       rs527666137       rs527726037       rs528125639       rs529749567       rs529814441       rs530090682       rs530500054       rs530643296       rs531121951       rs531634659       rs531845348       rs531897946       rs531983625       rs532368496       rs533404165       rs533527028       rs533709947       rs533896742       rs535279245       rs535343184       rs535506333       rs535830857       rs535891325       rs537160715       rs537499841       rs537683251       rs537691347       rs537960085       rs539337157       rs539691076       rs539760169       rs539892859       rs540005092       rs540243268       rs540887305       rs540952519       rs541620668       rs541907116       rs543195170       rs543888028       rs544607095       rs545330170       rs545512078       rs546234177       rs546727339       rs546790290       rs546950563       rs547116614       rs547872938       rs549030133       rs549324046       rs550187568       rs551551195       rs551613549       rs551748369       rs553214152       rs554486392       rs555201881       rs555213418       rs555267237       rs555420144       rs556481048       rs557006939       rs557147303       rs557190713       rs557270747       rs557537721       rs557600540       rs558959515       rs559403602       rs559468842       rs560326328       rs560390079       rs560766762       rs560792653       rs560830984       rs561406898       rs561622114       rs562635047       rs562812808       rs563441583       rs563710095       rs565301824       rs565488169       rs565630324       rs566364828       rs566619548       rs566703314       rs567075960       rs567681532       rs569115484       rs569657780       rs570985403       rs571308012       rs571435275       rs571503439       rs572515744       rs573041269       rs573321697       rs573989604       rs574328173       rs574981089       rs575042797       rs575168573       rs575552456       rs575909363       rs576140459       rs576533073       rs576672405       rs577091767       rs577194940       rs577245776       rs577264122       rs577655720       rs745317270       rs745539034       rs746091568       rs746460936       rs746681575       rs746818002       rs747099566       rs747099778       rs747340681       rs747594518       rs747730129       rs748272652       rs748800457       rs748974019       rs749320488       rs749556308       rs749642774       rs749689536       rs749705374       rs749888818       rs749965375       rs750019677       rs750753249       rs750993043       rs751204472       rs751333829       rs751564815       rs751571473       rs751574445       rs751735830       rs751803379       rs752161587       rs752472421       rs752652915       rs753050018       rs753319613       rs753343877       rs753515072       rs754478446       rs754588977       rs754636153       rs755004731       rs755549967       rs755776437       rs756698222       rs757176576       rs757222810       rs758442899       rs758730051       rs758888528       rs759037664       rs759094134       rs759500684       rs759682364       rs759782481       rs759814847       rs760092093       rs760196559       rs760502900       rs760530553       rs760657299       rs760849304       rs760900335       rs761168295       rs761325297       rs761666660       rs761933196       rs762039557       rs762336482       rs762609098       rs762836929       rs762855347       rs763403336       rs763458427       rs763696008       rs764176353       rs764192398       rs764733870       rs764749715       rs764788458       rs764907828       rs764970320       rs765210155       rs765389900       rs765605213       rs766073076       rs766452229       rs766567273       rs766690181       rs766871395       rs767225140       rs767473145       rs767605458       rs767816568       rs767960035       rs768853099       rs768884148       rs768985984       rs769096129       rs769179103       rs769661323       rs770078235       rs770234243       rs770734901       rs770765673       rs770838260       rs771126518       rs771403137       rs771683571       rs771914443       rs772144480       rs772496741       rs772565792       rs772623581       rs772966039       rs773175557       rs773179563       rs773290508       rs773697080       rs773702206       rs773765965       rs774279559       rs774342582       rs774645637       rs775339707       rs775375851       rs775483671       rs775667220       rs775826826       rs775886938       rs776208108       rs776360467       rs776587636       rs776598587       rs776733818       rs776818865       rs776970950       rs777366189       rs777967633       rs778340765       rs778706552       rs779188416       rs779251965       rs779256288       rs779673125       rs779779208       rs779809128       rs780289383       rs780480112       rs780969560       rs781380689       rs781601256       rs781720797      

基因表达

基因表达

IFI30基因在不同组织中的表达：    [UniProt]

基因在不同组织中的表达图

基因引物

基因引物

正向引物序列
正向引物Tm值
反向引物序列
反向引物Tm值
rank
ACTTGACATGGAGCTAGCC
60
TAGAGCTGCAGGCATAGTG
59
CACCAGTTAACTACAAGACAGG
59
GAGGGTCACATTGACAAGC
59
GAACTTGACATGGAGCTAGC
59
TAGAGCTGCAGGCATAGTG
59
CTTGACATGGAGCTAGCCT
59
TAGAGCTGCAGGCATAGTG
59
CCACCAGTTAACTACAAGACAG
59
GAGGGTCACATTGACAAGC
59
CCAGTTAACTACAAGACAGGC
59
GAGGGTCACATTGACAAGC
59

转录因子

转录因子

      尚未收录相关数据

基因本体信息

IFI30基因（以及对应的蛋白质）的细胞分布位置：

[UniProt]     [GenomeNet]

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • 溶酶体
  • 内涵体
  • 细胞核
  • 细胞质
  • 液泡
  • 细胞膜
  • 细胞外基质
  • 内质网
  • 线粒体
  • 高尔基体
  • 细胞骨架

IFI30基因的本体（GO）信息：

GO库代码
对应的蛋白质
来源代码
GO:0005515
P13284(UniProtKB)
IPI
GO:0005515
P13284(UniProtKB)
IPI
GO:0005576
P13284(UniProtKB)
IEA
GO:0005737
P13284(UniProtKB)
IDA
GO:0005764
P13284(UniProtKB)
IDA
GO:0005886
P13284(UniProtKB)
IDA
GO:0016667
P13284(UniProtKB)
EXP
GO:0016667
P13284(UniProtKB)
IMP
GO:0016667
P13284(UniProtKB)
EXP
GO:0019886
P13284(UniProtKB)
TAS
GO:0030054
P13284(UniProtKB)
IDA
GO:0042590
P13284(UniProtKB)
ISS
GO:0043202
P13284(UniProtKB)
TAS
GO:0043202
P13284(UniProtKB)
TAS
GO:0043231
P13284(UniProtKB)
IDA
GO:0048147
P13284(UniProtKB)
IEA
GO:0050821
P13284(UniProtKB)
IEA
GO:0055114
P13284(UniProtKB)
IEA
GO:0060333
P13284(UniProtKB)
TAS

基因相互作用关系

基因相互作用关系

基因与其他基因之间的相互作用关系图
序号 作用方式 资源库来源/分值 基因名称 基因名称

基因相关microRNA

基因相关microRNA

可能调控IFI30基因的相关microRNA：     

基因通路图

基因通路图

基因的通路属性图
通路基因列表

基因相关疾病

基因相关疾病

疾病名称 关系值 NofPmids NofSnps 来源
疾病名称 关系值 NofPmids NofSnps 来源
Leukemia, Myelocytic, Acute 0.12 1 0 CTD_human
Dermatitis, Allergic Contact 0.12 1 0 CTD_human
melanoma 0.005720142 3 0 BeFree_LHGDN
Neuromyelitis Optica 0.002995792 1 0 BeFree_LHGDN
Obesity 0.000542884 2 1 BeFree
Malignant neoplasm of breast 0.000271442 1 0 BeFree
Cardiovascular Diseases 0.000271442 1 0 BeFree
Diabetes 0.000271442 1 1 BeFree
Diabetes Mellitus 0.000271442 1 1 BeFree
Hyperglycemia 0.000271442 1 0 BeFree
Liver Cirrhosis 0.000271442 1 0 BeFree
Carcinoma breast stage IV 0.000271442 1 0 BeFree
Metabolic Syndrome X 0.000271442 1 0 BeFree
Breast Carcinoma 0.000271442 1 0 BeFree
Tumor Immunity 0.000271442 1 0 BeFree
Cirrhosis 0.000271442 1 0 BeFree
Experimental Organism Basal Cell Carcinoma 0.000271442 1 0 BeFree

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