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The protein encoded by this gene is a helix-loop-helix (HLH) protein that can form heterodimers with other HLH proteins. However, the encoded protein lacks a basic DNA-binding domain and therefore inhibits the DNA binding of any HLH protein with which it interacts. [provided by RefSeq, Aug 2011]
[中文简述(自动翻译):]  由该基因编码的蛋白质是可以形成具有其他HLH蛋白异二聚体螺旋 - 环 - 螺旋(HLH)蛋白。然而,编码的蛋白质缺少一个基本的DNA结合结构域,因此,抑制该DNA与它相互作用的任何HLH蛋白的结合。 [由RefSeq的,2011年8月提供]
ID3基因(以及对应的蛋白质)的细胞分布位置:
ID3基因的本体(GO)信息:
| 疾病名称 | 关系值 | NofPmids | NofSnps | 来源 |
| Burkitt Lymphoma | 0.120542884 | 3 | 0 | BeFree_CTD_human |
| Adenocarcinoma | 0.120271442 | 2 | 0 | BeFree_CTD_human |
| Prostatic Neoplasms | 0.120271442 | 2 | 0 | BeFree_CTD_human |
| Colonic Neoplasms | 0.12 | 1 | 0 | CTD_human |
| Lung Neoplasms | 0.12 | 1 | 0 | CTD_human |
| Animal Mammary Neoplasms | 0.12 | 1 | 0 | CTD_human |
| Mammary Neoplasms, Experimental | 0.12 | 1 | 0 | CTD_human |
| nervous system disorder | 0.12 | 1 | 0 | CTD_human |
| Peripheral Neuropathy | 0.12 | 1 | 0 | CTD_human |
| Reperfusion Injury | 0.12 | 1 | 0 | CTD_human |
| Thyroid Diseases | 0.12 | 1 | 0 | CTD_human |
| Myocardial Ischemia | 0.12 | 1 | 0 | CTD_human |
| Sjogren's Syndrome | 0.08 | 0 | 0 | MGD |
| Malignant neoplasm of prostate | 0.005005506 | 3 | 0 | BeFree_GAD |
| Atherosclerosis | 0.003181358 | 4 | 0 | BeFree_GAD |
| Rett Syndrome | 0.00272435 | 1 | 0 | LHGDN |
| Stomach Neoplasms | 0.00272435 | 1 | 0 | LHGDN |
| Carotid Artery Diseases | 0.002367032 | 1 | 0 | GAD |
| Diabetes Mellitus, Non-Insulin-Dependent | 0.002367032 | 1 | 0 | GAD |
| Arteriosclerosis | 0.000814326 | 3 | 0 | BeFree |
| Ovarian Carcinoma | 0.000542884 | 2 | 0 | BeFree |
| Thyroid carcinoma | 0.000542884 | 2 | 0 | BeFree |
| Malignant neoplasm of ovary | 0.000542884 | 2 | 0 | BeFree |
| Malignant neoplasm of thyroid | 0.000271442 | 1 | 0 | BeFree |
| Squamous cell carcinoma | 0.000271442 | 1 | 0 | BeFree |
| Diabetes | 0.000271442 | 1 | 0 | BeFree |
| Diabetes Mellitus | 0.000271442 | 1 | 0 | BeFree |
| Diabetes Mellitus, Insulin-Dependent | 0.000271442 | 1 | 0 | BeFree |
| leukemia | 0.000271442 | 1 | 0 | BeFree |
| Chronic Lymphocytic Leukemia | 0.000271442 | 1 | 0 | BeFree |
| Acute Erythroblastic Leukemia | 0.000271442 | 1 | 0 | BeFree |
| Neoplasm Metastasis | 0.000271442 | 1 | 0 | BeFree |
| Neuroblastoma | 0.000271442 | 1 | 0 | BeFree |
| Thyroid Neoplasm | 0.000271442 | 1 | 0 | BeFree |
| Diffuse Large B-Cell Lymphoma | 0.000271442 | 1 | 0 | BeFree |
| T-Cell Lymphoma | 0.000271442 | 1 | 0 | BeFree |
| Adenocarcinoma of lung (disorder) | 0.000271442 | 1 | 0 | BeFree |
| Prostate carcinoma | 0.000271442 | 1 | 0 | BeFree |
| Central neuroblastoma | 0.000271442 | 1 | 0 | BeFree |
| Depression in children | 0.000271442 | 1 | 0 | BeFree |
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