ICAM5(intercellular adhesion molecule 5, telencephalin)

基因基本信息

基因基本信息

基因简称(symbol)
    [HGNC]     [GeneCards]     [NCBI]
基因种类(locus group)
同源简称(alias symbol)
基因家族代码(gene_family_id)
    [HGNC]     [GenScript]
omim代码
entrez码
    [Vega]
vega基因码
ensembl基因码
    [Ensembl]
基因家族(gene family)
refseq数据库代号

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基因种类(locus_type)
基因名称状态(status)
location_sortable
同源基因名称(alias name)
基因名称批准使用时间(date_approved_reserved)
基因简称更名时间(date_symbol_changed)
基因名称更名时间(date_name_changed)
更新时间(date_modified)
ucsc码
ena
ccds数据码
uniprot数据码
pubmed代码
mgd码
rgd码
生命科学数据库(lsdb)
更新时间(date modified)
cosmic
mirbase
基因曾用简称(prev symbol)
基因曾用名称(prev name)
homeodb
cosmic
snornabase
bioparadigms slc
orphanet
假基因信息(pseudogeneorg)
horde id
merops
imgt
iuphar
kznf基因类别
mamit-trnadb
cd
LncRNA数据库
酶代码
中间纤维数据库

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基因染色体位置

基因染色体位置

19p13.2
基因染色体位置图

基因简述

基因简述

The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is expressed on the surface of telencephalic neurons and displays two types of adhesion activity, homophilic binding between neurons and heterophilic binding between neurons and leukocytes. It may be a critical component in neuron-microglial cell interactions in the course of normal development or as part of neurodegenerative diseases. [provided by RefSeq, Jul 2008]

[中文简述(自动翻译):]  由该基因编码的蛋白质是细胞间粘附分子（ICAM）家族的一个成员。所有的ICAM蛋白质是I型跨膜糖蛋白，含有2-9免疫球蛋白样C2型结构域，以及结合到白细胞粘附LFA-1的蛋白质。这种蛋白质被表达端脑的神经元的表面上，并显示两种类型的粘附活性，同嗜神经元和嗜异性神经元和白细胞之间的结合之间的结合。它可以是在正常发育过程中或作为神经变性疾病的部分神经元的小神经胶质细胞的相互作用的关键组件。 [由RefSeq的，2008年7月提供]

OMIM数据库中对ICAM5基因的介绍     Wikipedia数据库中对ICAM5基因的介绍

基因序列

基因序列

ICAM5基因的碱基序列：[NCBI]

基因突变

基因突变

ICAM5基因的碱基突变：           显示全部snp
rs281438       rs3093029       rs3745267       rs5030385       rs34274798       rs34385135       rs34778003       rs34925519       rs35078242       rs35165411       rs36023325       rs36110042       rs55761920       rs75264555       rs113892276       rs115855638       rs140289465       rs141101411       rs142025233       rs142109230       rs144913870       rs145209145       rs145323966       rs145697899       rs146427583       rs147458509       rs151158164       rs184847594       rs188777743       rs200228336       rs200471341       rs201399464       rs368901409       rs369632584       rs370615268       rs371076614       rs371910762      
rs373009181       rs375526250       rs377076712       rs377470882       rs377604730       rs536149845       rs539994937       rs540595516       rs541706023       rs542450359       rs543532609       rs544219094       rs552316014       rs557626088       rs559232816       rs563528779       rs568770787       rs571059786       rs572585716       rs575733288       rs576131531       rs745691639       rs745781332       rs746352738       rs747023961       rs747026880       rs747607311       rs747694527       rs748201755       rs748372509       rs749028766       rs749477052       rs749551837       rs750159706       rs750564722       rs750731494       rs750773201       rs751034035       rs751247769       rs753845734       rs753933674       rs754832864       rs755494782       rs755583690       rs755759895       rs756322389       rs757428309       rs757516126       rs757624505       rs757827547       rs758114506       rs758686500       rs758847209       rs758932037       rs759055313       rs759533488       rs759826978       rs760105445       rs761034821       rs761536113       rs761626067       rs761892488       rs762373199       rs762728283       rs763036721       rs764133200       rs765268784       rs766655632       rs766820266       rs766979276       rs767069162       rs767071656       rs767480804       rs767944077       rs768014944       rs768046370       rs768689512       rs768844056       rs769091807       rs769629691       rs769960980       rs770634773       rs770792909       rs771977233       rs772322610       rs772921849       rs773015279       rs774167545       rs774288442       rs775023987       rs775301160       rs775968659       rs776321792       rs776408886       rs776924459       rs777108705       rs777970931       rs779110405       rs779310858       rs779966296       rs780622559       rs780710490       rs780802328       rs780857348       rs781196046       rs781281480       rs781614874       rs281439       rs281440       rs710845       rs735747       rs885743       rs901886       rs1056536       rs1056538       rs2075741       rs2075742       rs2228615       rs2569693       rs2569694       rs2569697       rs2569700       rs2569701       rs2569702       rs2569703       rs10402760       rs10418913       rs11575073       rs11575074       rs11669397       rs11673661       rs12610026       rs12972990       rs17852402       rs28485475       rs34124276       rs34403566       rs34669551       rs35099361       rs35225729       rs35318566       rs35654716       rs35797244       rs36045754       rs36081155       rs74827019       rs75095909       rs75151412       rs76195573       rs77923045       rs78432167       rs78617778       rs79356289       rs80066865       rs80121752       rs80159611       rs111584571       rs112681371       rs114980880       rs115546433       rs115870389       rs116381263       rs116688659       rs139899408       rs139993605       rs140395213       rs140852122       rs141394381       rs141583702       rs143181516       rs143556346       rs144063436       rs144205613       rs144234155       rs144459501       rs145208316       rs145824055       rs146416564       rs147074144       rs147452916       rs147604357       rs148312881       rs148476026       rs148788922       rs149242279       rs149309075       rs150342965       rs150397383       rs150703171       rs150873217       rs151211439       rs180744933       rs181525927       rs181890650       rs182895147       rs183688456       rs185076445       rs186230061       rs186295295       rs188344435       rs189430286       rs190337900       rs190411743       rs199664255       rs199738344       rs200000538       rs200192686       rs200196487       rs200251866       rs200293534       rs200631718       rs200758108       rs200968160       rs201216338       rs201522317       rs201577589       rs201672754       rs201706206       rs201752473       rs201933364       rs202091893       rs367615849       rs367687699       rs368208108       rs368250065       rs369314723       rs369355624       rs369599293       rs369916316       rs370419581       rs370564477       rs370603381       rs370605902       rs370726702       rs370741150       rs371136676       rs371224402       rs371469473       rs371662961       rs372109882       rs372187269       rs372674108       rs372704058       rs373149643       rs373250130       rs373265158       rs373468253       rs373832722       rs373911810       rs374282567       rs374282883       rs374361583       rs375009422       rs375116134       rs375527133       rs375655248       rs376445768       rs376558743       rs376570687       rs376924939       rs377323998       rs377423531       rs398040885       rs527336666       rs527934682       rs528508231       rs528634241       rs529309010       rs529327455       rs529364836       rs529586587       rs529864146       rs530246865       rs530944662       rs531033540       rs531952159       rs532226729       rs534071602       rs534108960       rs534322155       rs534440907       rs535080433       rs535115715       rs535327850       rs535370279       rs535529666       rs535679115       rs536016126       rs536342739       rs536778200       rs537140076       rs537423937       rs538056764       rs538739779       rs538772813       rs539054132       rs539376521       rs539659591       rs540124272       rs540400022       rs540436743       rs540589528       rs541400232       rs541606142       rs541707298       rs541908305       rs542345526       rs542582225       rs542656397       rs543369803       rs544327117       rs544677082       rs545008431       rs545041374       rs545680188       rs545983112       rs546067469       rs546972842       rs547235050       rs547305295       rs547628221       rs548326795       rs548960289       rs549127966       rs549321708       rs549992190       rs550627359       rs550694678       rs550917502       rs550932570       rs551442855       rs551479437       rs551514342       rs552030450       rs552498004       rs552932424       rs554379963       rs555553140       rs556039606       rs556870986       rs556906899       rs557241655       rs557700551       rs558164614       rs558246490       rs559003853       rs559111361       rs559135150       rs559193618       rs559232630       rs560113411       rs560262128       rs560300590       rs561349727       rs561639656       rs561860354       rs562103036       rs562610488       rs562772013       rs563635509       rs564534820       rs564578284       rs566460756       rs566708553       rs566775151       rs567415257       rs567508911       rs567556774       rs567821379       rs568660378       rs568700197       rs568816242       rs569416626       rs569458534       rs570101584       rs570171962       rs570847118       rs571177789       rs571210197       rs571336166       rs573051864       rs573140592       rs573759852       rs574075657       rs574092397       rs575066789       rs575420371       rs575493903       rs575567213       rs576045524       rs576101932       rs576408367       rs577573555       rs578005327       rs578085799       rs745448446       rs745487938       rs745563293       rs745669878       rs745837260       rs745979453       rs745981138       rs746170713       rs746261178       rs746314749       rs746429867       rs746439147       rs746546706       rs746709347       rs746803527       rs746833456       rs746882678       rs747242567       rs747493164       rs747662666       rs747788624       rs747796224       rs747879148       rs747925443       rs747968130       rs748019273       rs748147937       rs748201501       rs748312107       rs748449966       rs748527748       rs748544440       rs748632307       rs748643377       rs748674899       rs748726167       rs748812071       rs748852454       rs748939311       rs749165436       rs749207610       rs749284253       rs749355381       rs749464135       rs749684915       rs749734248       rs749793668       rs749820628       rs749856101       rs749895372       rs749948901       rs749976445       rs750125061       rs750136766       rs750238652       rs750250084       rs750361196       rs750540023       rs750548095       rs750832737       rs750961266       rs750963125       rs751019923       rs751059736       rs751169415       rs751179388       rs751538371       rs751609350       rs751662614       rs751764474       rs751823463       rs751848482       rs751902593       rs751978302       rs752095056       rs752150067       rs752386181       rs752515250       rs752645471       rs752696053       rs752833273       rs752907691       rs752910728       rs752964755       rs753008492       rs753009545       rs753054026       rs753127277       rs753294969       rs753340425       rs753480140       rs753519969       rs753531594       rs753753078       rs753779713       rs754057362       rs754060140       rs754112321       rs754162546       rs754262935       rs754389788       rs754506496       rs754587787       rs754650970       rs754892778       rs755022271       rs755186666       rs755203339       rs755239785       rs755265044       rs755680109       rs755749166       rs755869492       rs755956477       rs756078267       rs756254678       rs756408708       rs756477605       rs756602664       rs756698057       rs756777035       rs756790595       rs756864615       rs756919676       rs757019816       rs757049124       rs757097057       rs757148302       rs757377841       rs757410416       rs757536996       rs757747046       rs757977282       rs757978671       rs758034503       rs758095126       rs758103269       rs758190772       rs758228996       rs758377916       rs758425056       rs758505262       rs758704689       rs758909223       rs758936792       rs759046287       rs759166183       rs759425530       rs759445262       rs759588861       rs759590640       rs759709582       rs759718105       rs759815089       rs759899104       rs760097857       rs760153562       rs760316037       rs760347968       rs760445703       rs760472678       rs760486398       rs760572744       rs760598879       rs760724643       rs760725113       rs760862700       rs761096972       rs761242187       rs761291282       rs761293492       rs761723946       rs761753686       rs761793606       rs761806703       rs761875101       rs761974756       rs761999669       rs762029745       rs762187540       rs762372264       rs762391964       rs762425335       rs762443000       rs762471340       rs762526366       rs762720374       rs762916382       rs762946340       rs763100288       rs763151043       rs763220847       rs763432638       rs763538042       rs763664362       rs763815969       rs763846097       rs763860388       rs763883768       rs763972793       rs764202759       rs764349446       rs764591497       rs764712907       rs764790873       rs765013341       rs765026177       rs765091105       rs765164743       rs765447145       rs765686383       rs765737682       rs765739661       rs765799576       rs765844530       rs765866534       rs765871959       rs765921500       rs765959391       rs765977465       rs766262202       rs766315761       rs766315764       rs766385840       rs766430144       rs766437903       rs766440041       rs766456168       rs766664471       rs766699029       rs766939276       rs767024873       rs767050587       rs767111591       rs767392970       rs767466112       rs767479516       rs767567981       rs767591124       rs767712563       rs767748025       rs768070421       rs768108345       rs768334317       rs768427761       rs768429598       rs768492302       rs768495461       rs768546380       rs768615612       rs768771634       rs769003700       rs769085228       rs769104245       rs769157278       rs769497172       rs769545435       rs769669282       rs769725861       rs769942517       rs769964078       rs770100361       rs770184795       rs770214808       rs770220683       rs770271293       rs770339845       rs770395003       rs770648638       rs770835595       rs770864531       rs771041441       rs771193899       rs771249059       rs771282852       rs771319048       rs771330490       rs771455208       rs771480339       rs771605027       rs771752095       rs771761367       rs771883744       rs771884086       rs771944642       rs771982287       rs772061314       rs772123824       rs772178904       rs772249843       rs772374571       rs772476365       rs772484021       rs772570246       rs772668420       rs772721226       rs772732398       rs772788488       rs773055599       rs773122595       rs773271448       rs773640360       rs773671928       rs773768844       rs773785177       rs773967044       rs774026450       rs774244492       rs774246409       rs774297418       rs774361931       rs774416813       rs774511257       rs774623176       rs774835810       rs774890992       rs774977646       rs775013785       rs775126079       rs775163669       rs775256074       rs775286706       rs775389277       rs775438082       rs775502255       rs775667116       rs775774681       rs775835159       rs775892862       rs776074465       rs776127692       rs776348928       rs776400501       rs776404071       rs776421450       rs776587690       rs776654486       rs776658252       rs776707908       rs776961429       rs777019168       rs777087484       rs777107358       rs777140585       rs777384734       rs777484334       rs777499826       rs777607316       rs777662175       rs778010360       rs778036058       rs778053270       rs778183339       rs778250292       rs778527355       rs778582454       rs778639272       rs778697900       rs778837551       rs778978320       rs779071361       rs779073267       rs779109370       rs779306991       rs779366879       rs779589222       rs779646880       rs779711819       rs779769643       rs779771575       rs779826713       rs779913260       rs780249348       rs780333706       rs780458607       rs780511464       rs780790044       rs780896076       rs780914791       rs781079752       rs781290622       rs781293487       rs781371355       rs781414676       rs781476206       rs781488060       rs781531482       rs781649424      

基因表达

基因表达

ICAM5基因在不同组织中的表达：    [UniProt]

基因在不同组织中的表达图

基因引物

基因引物

正向引物序列
正向引物Tm值
反向引物序列
反向引物Tm值
rank
TGAATTGCAGCACCAACTG
59
AGCTCAGGGTGAAGTTCTC
59
TTTGGAGACCATGGCTCTC
59
CCCAGAGTCTAAACCTCGAG
59
CTCATTCGCACTTTCCAGC
60
AGCTCAGGGTGAAGTTCTC
59
GTGACCATCTACAGCTTCC
58
CAGGTTACTGTCACCATCTG
58
TTTGGAGACCATGGCTCTC
59
CCAGAGTCTAAACCTCGAGG
59
GTGACCATCTACAGCTTCC
58
GGTTACTGTCACCATCTGC
58
TGAATTGCAGCACCAACTG
59
ATCTGGTCGCTCTGTAGTG
59
GTGACCATCTACAGCTTCC
58
CAGGTTACTGTCACCATCTG
58
TTTGGAGACCATGGCTCTC
59
CCCAGAGTCTAAACCTCGA
58
TGACCATCTACAGCTTCCC
59
CAGGTTACTGTCACCATCTG
58

转录因子

转录因子

      尚未收录相关数据

基因本体信息

ICAM5基因（以及对应的蛋白质）的细胞分布位置：

[UniProt]     [GenomeNet]

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • 溶酶体
  • 内涵体
  • 细胞核
  • 细胞质
  • 液泡
  • 细胞膜
  • 细胞外基质
  • 内质网
  • 线粒体
  • 高尔基体
  • 细胞骨架

ICAM5基因的本体（GO）信息：

GO库代码
对应的蛋白质
来源代码
GO:0016020
K7EIL3(UniProtKB)
IEA
GO:0016337
K7EIL3(UniProtKB)
IEA
GO:0005178
Q9UMF0(UniProtKB)
IBA
GO:0005515
Q9UMF0(UniProtKB)
IPI
GO:0005886
Q9UMF0(UniProtKB)
TAS
GO:0005887
Q9UMF0(UniProtKB)
TAS
GO:0006909
Q9UMF0(UniProtKB)
IEA
GO:0007155
Q9UMF0(UniProtKB)
IBA
GO:0016337
Q9UMF0(UniProtKB)
IEA
GO:0030198
Q9UMF0(UniProtKB)
TAS
GO:0050776
Q9UMF0(UniProtKB)
TAS

基因相互作用关系

基因相互作用关系

基因与其他基因之间的相互作用关系图
序号 作用方式 资源库来源/分值 基因名称 基因名称

基因相关microRNA

基因相关microRNA

可能调控ICAM5基因的相关microRNA：     

基因通路图

基因通路图

基因的通路属性图
通路基因列表

基因相关疾病

基因相关疾病

疾病名称 关系值 NofPmids NofSnps 来源
疾病名称 关系值 NofPmids NofSnps 来源
Mammary Neoplasms 0.120271442 2 0 BeFree_CTD_human
Colorectal Neoplasms 0.12 2 0 CTD_human
Inflammatory dermatosis 0.12 1 1 GWASCAT
Malignant neoplasm of prostate 0.002638474 1 0 BeFree_GAD
Hepatitis C 0.002367032 1 0 GAD
Multiple Myeloma 0.002367032 1 0 GAD
Malignant neoplasm of breast 0.000542884 2 3 BeFree
Breast Carcinoma 0.000542884 2 3 BeFree
Squamous cell carcinoma 0.000271442 1 0 BeFree
Adenoid Cystic Carcinoma 0.000271442 1 0 BeFree
Head and Neck Neoplasms 0.000271442 1 0 BeFree
Lupus Erythematosus, Systemic 0.000271442 1 0 BeFree
Carcinogenesis 0.000271442 1 0 BeFree
Prostate carcinoma 0.000271442 1 0 BeFree

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