ICAM3(intercellular adhesion molecule 3) 转至新版数据库

基因简称(symbol)
    [HGNC]     [GeneCards]     [NCBI]
基因种类(locus group)
同源简称(alias symbol)
基因家族代码(gene_family_id)
    [HGNC]     [GenScript]
omim代码
entrez码
    [Vega]
vega基因码
ensembl基因码
    [Ensembl]
基因家族(gene family)
refseq数据库代号

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基因种类(locus_type)
基因名称状态(status)
location_sortable
同源基因名称(alias name)
基因名称批准使用时间(date_approved_reserved)
基因简称更名时间(date_symbol_changed)
基因名称更名时间(date_name_changed)
更新时间(date_modified)
ucsc码
ena
ccds数据码
uniprot数据码
pubmed代码
mgd码
rgd码
生命科学数据库(lsdb)
更新时间(date modified)
cosmic
mirbase
基因曾用简称(prev symbol)
基因曾用名称(prev name)
homeodb
cosmic
snornabase
bioparadigms slc
orphanet
假基因信息(pseudogeneorg)
horde id
merops
imgt
iuphar
kznf基因类别
mamit-trnadb
cd
LncRNA数据库
酶代码
中间纤维数据库

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19p13.3-p13.2
基因染色体位置图

The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is constitutively and abundantly expressed by all leucocytes and may be the most important ligand for LFA-1 in the initiation of the immune response. It functions not only as an adhesion molecule, but also as a potent signalling molecule. [provided by RefSeq, Jul 2008]

[中文简述(自动翻译):]  由该基因编码的蛋白质是细胞间粘附分子(ICAM)家族的一个成员。所有的ICAM蛋白质是I型跨膜糖蛋白,含有2-9免疫球蛋白样C2型结构域,以及结合到白细胞粘附LFA-1的蛋白质。这种蛋白是组成型和所有白细胞中大量表达,可能是对于LFA-1的免疫反应的开始时的最重要的配位体。它的功能不仅是作为一种粘附分子,也可作为有效的信号分子。 [由RefSeq的,2008年7月提供]

ICAM3基因的碱基序列:[NCBI]
ICAM3基因的碱基突变:           显示全部snp
rs281413       rs281414       rs281415       rs1058154       rs2230399       rs2278442       rs2304237       rs2304238       rs2304239       rs2304240       rs3176764       rs3176766       rs3176767       rs3176768       rs3176769       rs3181046       rs3181047       rs4804501       rs4804502       rs7249914       rs7250300       rs7250656       rs7253912       rs7254041       rs7254330       rs7257871       rs7258015       rs7408233       rs7409490       rs10403396       rs10406010       rs10408916       rs12462167       rs17000699       rs17000708       rs17697947       rs34642407      
rs35633871       rs57518295       rs61198164       rs61451658       rs62130698       rs73924331       rs74644412       rs74926565       rs75044914       rs76099911       rs76109397       rs76262170       rs77358503       rs77489484       rs78195795       rs78344052       rs78404141       rs79330474       rs80262216       rs111473857       rs111617519       rs111769245       rs111906193       rs112229693       rs112237432       rs112490934       rs112775107       rs113147780       rs113160220       rs113922888       rs114745284       rs115037728       rs115947017       rs116900565       rs117814624       rs117942573       rs137926345       rs138387368       rs138420692       rs138501169       rs138981703       rs139064130       rs139240933       rs139809893       rs139851139       rs140468498       rs141412554       rs141585231       rs141587193       rs141604438       rs142122662       rs142229827       rs142276897       rs143084546       rs143303720       rs144377929       rs144533070       rs144550290       rs145126073       rs145178286       rs145220995       rs145644715       rs145741513       rs145896733       rs146124000       rs146211701       rs146551417       rs147198376       rs147394556       rs147817956       rs147827519       rs148348101       rs148371008       rs148431551       rs148683888       rs148734511       rs148956626       rs148996243       rs149160125       rs149265917       rs149311984       rs149452721       rs149796645       rs149954751       rs150715220       rs180880930       rs181670497       rs182001292       rs183563122       rs184444511       rs185282885       rs185979499       rs186415008       rs188047990       rs188115789       rs188808991       rs189583530       rs190884203       rs191247033       rs191885343       rs192527584       rs199759488       rs199780600       rs199813169       rs200047831       rs200224009       rs200281917       rs200308522       rs200316609       rs200757047       rs200757543       rs200775651       rs200939629       rs201084371       rs201217111       rs201301472       rs201406506       rs201412519       rs201762047       rs201834441       rs201917460       rs202018816       rs202215753       rs367997761       rs368034000       rs368063966       rs368579277       rs368870942       rs369091029       rs369252388       rs369272188       rs369522828       rs369543381       rs369922612       rs370216635       rs370395857       rs370501247       rs370694366       rs370897794       rs371332254       rs371471045       rs371551673       rs371615530       rs372114632       rs372160230       rs372536524       rs372769379       rs373075234       rs373165638       rs373239893       rs373670278       rs374056612       rs374246978       rs374301951       rs374344686       rs374707916       rs374823074       rs375185006       rs375409719       rs375684488       rs375739786       rs376229949       rs376351840       rs376533851       rs376538520       rs376684785       rs376924405       rs376983106       rs377165356       rs377240440       rs377248857       rs377313574       rs377325984       rs377604127       rs377712620       rs398040888       rs527279406       rs527316385       rs527545083       rs527877890       rs527877953       rs527914722       rs528196976       rs528465784       rs528988477       rs529241980       rs530930914       rs531439779       rs531655402       rs531924742       rs532337533       rs532385286       rs532765767       rs532802063       rs532825765       rs533067914       rs533315249       rs533553294       rs533801108       rs533960934       rs534620381       rs534708620       rs534988269       rs535394565       rs535408083       rs535509279       rs535651435       rs535983380       rs536712492       rs536975880       rs539012850       rs539321601       rs539360324       rs540019072       rs540248931       rs541048548       rs541203867       rs541282387       rs541641152       rs542285625       rs543035295       rs543221667       rs543240567       rs543383673       rs544182900       rs544342771       rs544576592       rs544627497       rs544662681       rs545418264       rs546230462       rs546645736       rs547632304       rs547939700       rs548707286       rs548911777       rs549768313       rs549869786       rs550635275       rs550910522       rs551218983       rs551293245       rs551374487       rs551416942       rs551647665       rs552017407       rs552295650       rs552304165       rs552325798       rs553025899       rs553063033       rs554174905       rs554213558       rs554299427       rs555026435       rs555156272       rs555338933       rs555611469       rs555829216       rs556372508       rs559108389       rs559476256       rs559596337       rs559810492       rs560640076       rs560676173       rs560685247       rs560800784       rs560949247       rs561475748       rs561564962       rs561755740       rs561806296       rs562703545       rs562740251       rs563171734       rs563905129       rs564147714       rs564866403       rs566102434       rs566126135       rs566165096       rs566379918       rs566961542       rs567161079       rs567299594       rs567530168       rs567833372       rs568001304       rs568004445       rs568103007       rs568139281       rs568399510       rs568517946       rs568800302       rs569389839       rs570484198       rs570507795       rs570544779       rs570793210       rs571063808       rs571308418       rs571461874       rs571823115       rs572430541       rs572712058       rs572799440       rs573451980       rs573810132       rs573971939       rs574060117       rs574644112       rs576016859       rs576276570       rs576554057       rs576591325       rs576665084       rs576869005       rs577324977       rs577411967       rs577994519       rs578040344       rs578254928       rs745307911       rs745441558       rs745487752       rs745617138       rs745739834       rs745953477       rs745995165       rs746077624       rs746120264       rs746132033       rs746178715       rs746245267       rs746276448       rs746348254       rs746354990       rs746464813       rs746642554       rs746664303       rs746875907       rs746910528       rs747026668       rs747046055       rs747173335       rs747323600       rs747431836       rs747564030       rs747699516       rs747824002       rs748016374       rs748069551       rs748204651       rs748245954       rs748294276       rs748450612       rs748450679       rs748526493       rs748575099       rs748690143       rs748751957       rs748950983       rs749034840       rs749099023       rs749115129       rs749170692       rs749269595       rs749560074       rs749576098       rs749732092       rs749783174       rs749790536       rs749864969       rs749933428       rs749991919       rs749993573       rs750220715       rs750307252       rs750496424       rs750642172       rs750684793       rs750746896       rs750748908       rs750873485       rs750939386       rs751008581       rs751092139       rs751110657       rs751243771       rs751253462       rs751344085       rs751456592       rs751524541       rs751533826       rs751648915       rs751713708       rs751724224       rs751840717       rs751965579       rs752014816       rs752201007       rs752433398       rs752495746       rs752601479       rs752649575       rs752717108       rs752843833       rs752895097       rs752991950       rs753055513       rs753103195       rs753180287       rs753358377       rs753529907       rs753571104       rs753583645       rs753624275       rs753734369       rs753849752       rs753979231       rs754032511       rs754174102       rs754301913       rs754323996       rs754446056       rs754545773       rs754625737       rs754658150       rs754902262       rs754942055       rs754960954       rs755012486       rs755072459       rs755125488       rs755146488       rs755272293       rs755314452       rs755474269       rs755495054       rs755547341       rs755764117       rs755779776       rs755873493       rs755932767       rs756040960       rs756058799       rs756117318       rs756172817       rs756173949       rs756208899       rs756386703       rs756575960       rs756688789       rs756778903       rs756840011       rs757110882       rs757128019       rs757180935       rs757287540       rs757337828       rs757419027       rs757551031       rs757719580       rs757776655       rs757861942       rs757913325       rs757937103       rs758037816       rs758065788       rs758095008       rs758137959       rs758342700       rs758435958       rs758463906       rs758475725       rs758532139       rs758603661       rs758982496       rs758988475       rs759021818       rs759049839       rs759102700       rs759486314       rs759669420       rs759693492       rs759877559       rs759878024       rs759958203       rs760032408       rs760085544       rs760148172       rs760183890       rs760224824       rs760348883       rs760388743       rs760440255       rs760660556       rs760770030       rs760927192       rs760959050       rs761052794       rs761073759       rs761160572       rs761215638       rs761463951       rs761473419       rs761513245       rs761531872       rs761724730       rs761839273       rs761993700       rs762062404       rs762230332       rs762381855       rs762494439       rs762676087       rs762746005       rs762850714       rs762867098       rs763035642       rs763096047       rs763128013       rs763253480       rs763351521       rs763362056       rs763368775       rs763388028       rs763420036       rs763543753       rs763575426       rs763741904       rs763916545       rs764040955       rs764141053       rs764185613       rs764468609       rs764529434       rs764540535       rs764604335       rs764654246       rs764654393       rs764827854       rs764875528       rs765025664       rs765038852       rs765064978       rs765097001       rs765108324       rs765270373       rs765308514       rs765324270       rs765498351       rs765670339       rs765672293       rs765790233       rs765803022       rs765827834       rs765852348       rs766001642       rs766015350       rs766053995       rs766195014       rs766254190       rs766373947       rs766396874       rs766451838       rs766453233       rs766620208       rs766746896       rs766816255       rs766912896       rs766972169       rs767085121       rs767152331       rs767286338       rs767321947       rs767401178       rs767414257       rs767523358       rs767738423       rs767745466       rs767922533       rs767965748       rs768023107       rs768074509       rs768302002       rs768313128       rs768362006       rs768630568       rs768760072       rs768855498       rs768930045       rs769036423       rs769038760       rs769274644       rs769463146       rs769501979       rs769542169       rs769547272       rs769661129       rs769886262       rs769904543       rs769954938       rs769994849       rs770061308       rs770091177       rs770163496       rs770215290       rs770245828       rs770250990       rs770261978       rs770325446       rs770370470       rs770425434       rs770509823       rs770631624       rs770666856       rs770747942       rs770797192       rs770941351       rs771126563       rs771277987       rs771294902       rs771350115       rs771402665       rs771617178       rs771759809       rs771784634       rs771805877       rs771806187       rs771835740       rs772096843       rs772102271       rs772254677       rs772282053       rs772399003       rs772574442       rs772639951       rs772823099       rs772838874       rs772940698       rs772988290       rs773029037       rs773043057       rs773151947       rs773241802       rs773322758       rs773335587       rs773379965       rs773665465       rs773681323       rs773844843       rs773890942       rs773971417       rs774120798       rs774571543       rs774624550       rs774747121       rs774755922       rs774903659       rs774938341       rs774952593       rs775062810       rs775127520       rs775186289       rs775290461       rs775291853       rs775301087       rs775317716       rs775492121       rs775601237       rs775697879       rs775753171       rs775879785       rs775884816       rs775959025       rs776009091       rs776092431       rs776366850       rs776445575       rs776505448       rs776578152       rs776728487       rs776899750       rs776965981       rs777019198       rs777134199       rs777328921       rs777354666       rs777428583       rs777684760       rs777806772       rs777846208       rs777859894       rs777934915       rs777985727       rs778166704       rs778189740       rs778211823       rs778262933       rs778463538       rs778546609       rs778616470       rs778760763       rs778812859       rs778849009       rs778932540       rs778933878       rs778974491       rs779055550       rs779184448       rs779314826       rs779504765       rs779523885       rs779579060       rs779631555       rs779683160       rs779688714       rs779764689       rs779981449       rs780001288       rs780099288       rs780150392       rs780204272       rs780220724       rs780426591       rs780606649       rs780662142       rs780710591       rs780831410       rs780833309       rs780961092       rs781107671       rs781277041       rs781293052       rs781308865       rs781406349       rs781445992       rs781606455       rs781613261      

ICAM3基因在不同组织中的表达:    [UniProt]

基因在不同组织中的表达图
正向引物序列
正向引物Tm值
反向引物序列
反向引物Tm值
rank
CAGGAACCCTTCTGTCTCG
60
CTGTACACGGTGATGTTAGAG
58
CAGTACTGATTGTCCCAGC
58
CAGCTCCTTTGATAGGGAC
57
CTTCCTCTGTCAGAATGGC
58
TGATCCAGCATAGGAGGAG
58
CTAAATGCTACCGAGAGTGAC
58
TTTGGGACCATACAGGACTC
59
TCTACCTTTCCCACTGGAC
58
CTGTACACGGTGATGTTAGAG
58
GTACTGATTGTCCCAGCTC
58
ACCAGCTCCTTTGATAGGG
59
CTAAATGCTACCGAGAGTGAC
58
TTGGGACCATACAGGACTC
58
ACTGGACCATGAAGGTGTC
59
CGTTGCTGAGATTGAAGGC
60
TTCCTCTGTCAGAATGGCC
59
TGATCCAGCATAGGAGGAG
58
TTCCTCTGTCAGAATGGCC
59
AAAGGGACAGGTGATCCTG
59
      尚未收录相关数据

ICAM3基因(以及对应的蛋白质)的细胞分布位置:

[UniProt]     [GenomeNet]

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • 溶酶体
  • 内涵体
  • 细胞核
  • 细胞质
  • 液泡
  • 细胞膜
  • 细胞外基质
  • 内质网
  • 线粒体
  • 高尔基体
  • 细胞骨架

ICAM3基因的本体(GO)信息:

GO库代码
对应的蛋白质
来源代码
GO:0016021
K7EP52(UniProtKB)
IEA
GO:0016020
K7EQC7(UniProtKB)
IEA
GO:0016337
K7EQC7(UniProtKB)
IEA
GO:0016021
K7ERF0(UniProtKB)
IEA
GO:0016021
K7ERN2(UniProtKB)
IEA
GO:0016337
K7ERN2(UniProtKB)
IEA
GO:0002223
P32942(UniProtKB)
TAS
GO:0005102
P32942(UniProtKB)
TAS
GO:0005178
P32942(UniProtKB)
IPI
GO:0005515
P32942(UniProtKB)
IPI
GO:0005515
P32942(UniProtKB)
IPI
GO:0005886
P32942(UniProtKB)
TAS
GO:0005886
P32942(UniProtKB)
TAS
GO:0005887
P32942(UniProtKB)
TAS
GO:0007155
P32942(UniProtKB)
IBA
GO:0016337
P32942(UniProtKB)
IEA
GO:0030198
P32942(UniProtKB)
TAS
GO:0050776
P32942(UniProtKB)
TAS
GO:0070062
P32942(UniProtKB)
IDA
GO:0070062
P32942(UniProtKB)
IDA
基因与其他基因之间的相互作用关系图
序号 作用方式 资源库来源/分值 基因名称 基因名称

可能调控ICAM3基因的相关microRNA:     


通路基因列表
疾病名称 关系值 NofPmids NofSnps 来源
疾病名称 关系值 NofPmids NofSnps 来源
Biliary cirrhosis 0.12 1 0 CTD_human
HIV Infections 0.002985861 11 0 BeFree
Mycosis Fungoides 0.00272435 1 0 LHGDN
Rheumatoid Arthritis 0.002638474 2 0 BeFree_GAD
Hepatitis C 0.002638474 2 0 BeFree_GAD
Severe Acute Respiratory Syndrome 0.002638474 2 0 BeFree_GAD
Tuberculosis 0.000542884 2 0 BeFree
Malignant tumor of cervix 0.000271442 1 0 BeFree
Esophageal Neoplasms 0.000271442 1 0 BeFree
Lymphoma 0.000271442 1 0 BeFree
Multiple Myeloma 0.000271442 1 0 BeFree
Degenerative polyarthritis 0.000271442 1 0 BeFree
Esophageal carcinoma 0.000271442 1 0 BeFree
Cervix carcinoma 0.000271442 1 0 BeFree
Malignant neoplasm of esophagus 0.000271442 1 0 BeFree
Stromal Neoplasm 0.000271442 1 0 BeFree
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