HSPE1(heat shock 10kDa protein 1)

基因基本信息

基因基本信息

基因简称(symbol)
    [HGNC]     [GeneCards]     [NCBI]
基因种类(locus group)
同源简称(alias symbol)
基因家族代码(gene_family_id)
    [HGNC]     [GenScript]
omim代码
entrez码
    [Vega]
vega基因码
ensembl基因码
    [Ensembl]
基因家族(gene family)
refseq数据库代号

更多...

基因种类(locus_type)
基因名称状态(status)
location_sortable
同源基因名称(alias name)
基因名称批准使用时间(date_approved_reserved)
基因简称更名时间(date_symbol_changed)
基因名称更名时间(date_name_changed)
更新时间(date_modified)
ucsc码
ena
ccds数据码
uniprot数据码
pubmed代码
mgd码
rgd码
生命科学数据库(lsdb)
更新时间(date modified)
cosmic
mirbase
基因曾用简称(prev symbol)
基因曾用名称(prev name)
homeodb
cosmic
snornabase
bioparadigms slc
orphanet
假基因信息(pseudogeneorg)
horde id
merops
imgt
iuphar
kznf基因类别
mamit-trnadb
cd
LncRNA数据库
酶代码
中间纤维数据库

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基因染色体位置

基因染色体位置

2q33.1
基因染色体位置图

基因简述

基因简述

This gene encodes a major heat shock protein which functions as a chaperonin. Its structure consists of a heptameric ring which binds to another heat shock protein in order to form a symmetric, functional heterodimer which enhances protein folding in an ATP-dependent manner. This gene and its co-chaperonin, HSPD1, are arranged in a head-to-head orientation on chromosome 2. Naturally occurring read-through transcription occurs between this locus and the neighboring locus MOBKL3.[provided by RefSeq, Feb 2011]

[中文简述(自动翻译):]  该基因编码的主要热休克蛋白，其功能是作为一个伴侣。其结构包括结合到另一热休克蛋白，以形成对称的，功能性异二聚体这增强在一个ATP依赖性蛋白质折叠一个七聚体环的。该基因和其共伴侣蛋白，HSPD1，排列成头 - 头方向上2号染色体的天然存在的通读转录发生此轨迹和相邻轨迹MOBKL3之间。[通过的RefSeq，2011年2月提供]

OMIM数据库中对HSPE1基因的介绍     Wikipedia数据库中对HSPE1基因的介绍

基因序列

基因序列

HSPE1基因的碱基序列：[NCBI]

基因突变

基因突变

HSPE1基因的碱基突变：           显示全部snp
rs13165       rs971009       rs1050347       rs1116734       rs2305559       rs2305560       rs2605039       rs2742264       rs3749094       rs10166418       rs11371120       rs11398993       rs11551346       rs11551347       rs11551349       rs16866252       rs16866259       rs34519984       rs59701865       rs66504718       rs67198751       rs67255036       rs67387011       rs72914958       rs73988475       rs74802652       rs75988349       rs78774346       rs78928314       rs79448126       rs79630442       rs79780284       rs80032346       rs80098019       rs112452204       rs112568177       rs112729982      
rs113357080       rs113661821       rs115857541       rs116282839       rs138716528       rs139114485       rs140886598       rs140946214       rs142886549       rs143093475       rs143630293       rs144973515       rs146042619       rs146156185       rs146859954       rs146997037       rs148530634       rs149376856       rs149631391       rs151029789       rs182518247       rs184016016       rs185690747       rs186911017       rs187006652       rs187028676       rs188661772       rs190669670       rs191128662       rs192327956       rs192349324       rs200514123       rs200985010       rs201599915       rs202082626       rs368813176       rs369029701       rs370142828       rs370386655       rs370664935       rs371942261       rs372780408       rs372847932       rs373057532       rs373587021       rs373852232       rs374253511       rs374968948       rs375104586       rs375552499       rs376221518       rs377047558       rs377646493       rs527861213       rs527930247       rs528474896       rs528611166       rs530178328       rs530341152       rs530775536       rs532243951       rs532584313       rs533132212       rs534485832       rs534508101       rs534524785       rs535071258       rs535071403       rs535199888       rs535414928       rs536233027       rs537905337       rs538715940       rs539370027       rs539674750       rs539950166       rs541225423       rs541343308       rs543332085       rs543438516       rs543605862       rs543699703       rs545912380       rs546209685       rs546616370       rs546848794       rs549768111       rs549936959       rs550031281       rs552704943       rs553081874       rs554812963       rs554949155       rs555025799       rs555087829       rs557012137       rs557264264       rs557286362       rs558757957       rs559169650       rs559511143       rs560495838       rs561100687       rs561165904       rs562154752       rs563362303       rs563816458       rs564376869       rs565153254       rs566023346       rs566424905       rs567353521       rs568228672       rs568292027       rs568478920       rs570058090       rs570654765       rs570971820       rs572474963       rs576027600       rs576126892       rs576807531       rs577339797       rs577475520       rs746651504       rs747094150       rs748015639       rs748262049       rs748584659       rs748743564       rs750060845       rs750112711       rs751801388       rs752498035       rs752797256       rs753141735       rs754385665       rs754852521       rs755791347       rs756657851       rs757412168       rs757619883       rs757895918       rs757923024       rs758433207       rs759437752       rs760016331       rs760120008       rs760949099       rs761441218       rs761748490       rs762965245       rs763415808       rs764224635       rs765119572       rs765781180       rs766023643       rs766989335       rs767791912       rs768653555       rs768660822       rs770044838       rs770178024       rs770231817       rs771238144       rs771871491       rs772267978       rs772319518       rs772856117       rs773500015       rs773618809       rs774482203       rs774521015       rs775461423       rs775744688       rs776111902       rs776485075       rs776524890       rs776654956       rs777306663       rs777349944       rs777798969       rs778003886       rs778032552       rs778457721       rs778531510       rs778657082       rs779633648       rs779789550       rs780279426       rs780655407       rs780891921       rs781405113       rs781536932       rs781615339       rs716800       rs1072612       rs6722363       rs6746661       rs76658309       rs78748166       rs79555488       rs80237505       rs111789198       rs114696119       rs117942610       rs138605020       rs140384586       rs142309856       rs143262995       rs143505856       rs147639869       rs147970259       rs149263633       rs180731514       rs182372784       rs182915235       rs183972000       rs185337726       rs186006149       rs188706855       rs189318443       rs190194320       rs190317439       rs200906251       rs368616761       rs369163255       rs371676153       rs372689034       rs373784782       rs374892675       rs377592618       rs377658442       rs527260297       rs529766416       rs531256994       rs531522978       rs533606913       rs534054944       rs536045223       rs536180526       rs538113248       rs538551803       rs540423673       rs542410221       rs542501777       rs542548933       rs543014482       rs544589091       rs544942305       rs549741484       rs553616205       rs553833083       rs556077789       rs559874032       rs559937415       rs560958955       rs562498551       rs567038174       rs567100980       rs568540912       rs569316489       rs571118024       rs571317094       rs573541295       rs575568957       rs575586515       rs577929605       rs578123150       rs745917629       rs748464908       rs749601737       rs750479587       rs751532202       rs751584150       rs758204031       rs759109641       rs759144317       rs760242924       rs761685029       rs762733464       rs764198783       rs764894979       rs765791864       rs766031328       rs768477167       rs769165271       rs772470500       rs772594093       rs774063842       rs774772244       rs776028460       rs776387426       rs778277413       rs779282649       rs780207908       rs780261670      

基因表达

基因表达

HSPE1基因在不同组织中的表达：    [UniProt]

基因在不同组织中的表达图

基因引物

基因引物

正向引物序列
正向引物Tm值
反向引物序列
反向引物Tm值
rank
AACTTGGAATATTGGGTGGAG
58
TGCCTCCATATTCTGGGAG
59
GTTCTAAAGGAAAGGGTGGAG
58
TGCCTCCATATTCTGGGAG
59
GAGTAATGGCAGGACAAGC
59
GGTTACAGTTTCAGCAGCA
58
TAAAGCTGGTCTGGTTGCT
59
GCTTGTCCTGCCAATATTCC
59
TTAAAGCTGGTCTGGTTGC
58
CTTGTCCTGCCAATATTCCA
58
CTTGGAATATTGGGTGGAGAG
58
TGGTGCCTCCATATTCTGG
59
GAGGGAGTAATGGGTGGAG
59
TGGTGCCTCCATATTCTGG
59
GGGAGTAATGGGTGGAGAG
59
TTGGTGCCTCCATATTCTGG
60
GGGAGTAATGGGTGGAGAG
59
TTTGGTGCCTCCATATTCTG
58
TTGGAATATTGGGTGGAGAG
57
TTGGTGCCTCCATATTCTG
57

转录因子

转录因子

      尚未收录相关数据

基因本体信息

HSPE1基因（以及对应的蛋白质）的细胞分布位置：

[UniProt]     [GenomeNet]

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • 溶酶体
  • 内涵体
  • 细胞核
  • 细胞质
  • 液泡
  • 细胞膜
  • 细胞外基质
  • 内质网
  • 线粒体
  • 高尔基体
  • 细胞骨架

HSPE1基因的本体（GO）信息：

GO库代码
对应的蛋白质
来源代码
GO:0005737
B8ZZ54(UniProtKB)
IEA
GO:0006457
B8ZZ54(UniProtKB)
IEA
GO:0005524
B8ZZL8(UniProtKB)
IEA
GO:0005737
B8ZZL8(UniProtKB)
IEA
GO:0006457
B8ZZL8(UniProtKB)
IEA
GO:0001649
P61604(UniProtKB)
IDA
GO:0005515
P61604(UniProtKB)
IPI
GO:0005515
P61604(UniProtKB)
IPI
GO:0005524
P61604(UniProtKB)
IEA
GO:0005739
P61604(UniProtKB)
ISS
GO:0005739
P61604(UniProtKB)
IDA
GO:0005759
P61604(UniProtKB)
IBA
GO:0006457
P61604(UniProtKB)
TAS
GO:0006919
P61604(UniProtKB)
NAS
GO:0006986
P61604(UniProtKB)
TAS
GO:0016020
P61604(UniProtKB)
IDA
GO:0044822
P61604(UniProtKB)
IDA
GO:0046872
P61604(UniProtKB)
IBA
GO:0051082
P61604(UniProtKB)
IBA
GO:0051082
P61604(UniProtKB)
NAS
GO:0051082
P61604(UniProtKB)
NAS
GO:0051085
P61604(UniProtKB)
IBA
GO:0051087
P61604(UniProtKB)
ISS
GO:0051087
P61604(UniProtKB)
IPI
GO:0070062
P61604(UniProtKB)
IDA
GO:0070062
P61604(UniProtKB)
IDA

基因相互作用关系

基因相互作用关系

基因与其他基因之间的相互作用关系图
序号 作用方式 资源库来源/分值 基因名称 基因名称

基因相关microRNA

基因相关microRNA

可能调控HSPE1基因的相关microRNA：     

基因通路图

基因通路图

基因的通路属性图
通路基因列表

基因相关疾病

基因相关疾病

疾病名称 关系值 NofPmids NofSnps 来源
疾病名称 关系值 NofPmids NofSnps 来源
Cardiomyopathies 0.12 1 0 CTD_human
Colorectal Neoplasms 0.00272435 1 0 LHGDN
Endometrial Neoplasms 0.00272435 1 0 LHGDN
Neoplasm Metastasis 0.00272435 1 0 LHGDN
Spastic Paraplegia, Hereditary 0.00272435 1 0 LHGDN
Malignant neoplasm of ovary 0.002638474 1 0 BeFree_GAD
Tuberculosis 0.001085767 4 0 BeFree
Autoimmune Diseases 0.000542884 2 0 BeFree
HIV Infections 0.000542884 2 0 BeFree
Carcinogenesis 0.000542884 2 0 BeFree
Bone Diseases 0.000271442 1 0 BeFree
Malignant neoplasm of breast 0.000271442 1 0 BeFree
Leprosy 0.000271442 1 0 BeFree
Liver neoplasms 0.000271442 1 0 BeFree
Lupus Erythematosus, Systemic 0.000271442 1 0 BeFree
Lupus Nephritis 0.000271442 1 0 BeFree
Mycobacterium Infections 0.000271442 1 0 BeFree
Nephritis 0.000271442 1 0 BeFree
Neuroblastoma 0.000271442 1 0 BeFree
Ovarian Carcinoma 0.000271442 1 0 BeFree
Breast Carcinoma 0.000271442 1 0 BeFree
Central neuroblastoma 0.000271442 1 0 BeFree
infertility tubal factor 0.000271442 1 0 BeFree
lupus cutaneous 0.000271442 1 0 BeFree
Adenoviral infections 0.000271442 1 0 BeFree
Liver carcinoma 0.000271442 1 0 BeFree

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