HOXC6(homeobox C6) 转至新版数据库

基因基本信息

基因基本信息

基因简称(symbol)
    [HGNC]     [GeneCards]     [NCBI]
基因种类(locus group)
同源简称(alias symbol)
基因家族代码(gene_family_id)
    [HGNC]     [GenScript]
omim代码
entrez码
    [Vega]
vega基因码
ensembl基因码
    [Ensembl]
基因家族(gene family)
refseq数据库代号

更多...

基因种类(locus_type)
基因名称状态(status)
location_sortable
同源基因名称(alias name)
基因名称批准使用时间(date_approved_reserved)
基因简称更名时间(date_symbol_changed)
基因名称更名时间(date_name_changed)
更新时间(date_modified)
ucsc码
ena
ccds数据码
uniprot数据码
pubmed代码
mgd码
rgd码
生命科学数据库(lsdb)
更新时间(date modified)
cosmic
mirbase
基因曾用简称(prev symbol)
基因曾用名称(prev name)
homeodb
cosmic
snornabase
bioparadigms slc
orphanet
假基因信息(pseudogeneorg)
horde id
merops
imgt
iuphar
kznf基因类别
mamit-trnadb
cd
LncRNA数据库
酶代码
中间纤维数据库

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基因染色体位置

基因染色体位置

12q13.13
基因染色体位置图

基因简述

基因简述

This gene belongs to the homeobox family, members of which encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene, HOXC6, is one of several HOXC genes located in a cluster on chromosome 12. Three genes, HOXC5, HOXC4 and HOXC6, share a 5' non-coding exon. Transcripts may include the shared exon spliced to the gene-specific exons, or they may include only the gene-specific exons. Alternatively spliced transcript variants encoding different isoforms have been identified for HOXC6. Transcript variant two includes the shared exon, and transcript variant one includes only gene-specific exons. [provided by RefSeq, Jul 2008]

[中文简述(自动翻译):]  该基因属于同源盒家族成员，其中编码的，在形态在所有的多细胞生物体中发挥重要作用的转录因子高度保守家族。哺乳动物具有项同类同源基因簇，HOXA，HOXB，HOXC和HOXD，它们位于不同的染色体上，并包括布置在串联9至11个基因。这个基因，HOXC6，是位于一??个簇号染色体上的12 3个基因，HOXC5，HOXC4和HOXC6，共享一个5‘非编码外显子的几个HOXC基因之一。转录可以包括接合到特定基因的外显子的外显子的共享，或者它们可以仅包括特定基因的外显子。另外剪接转录变体编码不同的亚型已经确定HOXC6。转录变异2包括共享外显子和转录变异一个包括只有特定的基因外显子。 [由RefSeq的，2008年7月提供]

OMIM数据库中对HOXC6基因的介绍     Wikipedia数据库中对HOXC6基因的介绍

基因序列

基因序列

HOXC6基因的碱基序列：[NCBI]

基因突变

基因突变

HOXC6基因的碱基突变：           显示全部snp
rs736825       rs746423       rs746424       rs754133       rs894735       rs894736       rs894737       rs894738       rs985125       rs1042245       rs1249077       rs1249078       rs2077177       rs3031471       rs3736210       rs3809157       rs3847782       rs3889697       rs4759318       rs4759319       rs7305320       rs7308105       rs7966202       rs10876527       rs10876528       rs10876529       rs10876530       rs11170787       rs11609476       rs11615193       rs12319419       rs12426399       rs12426706       rs55709517       rs56112137       rs56192173       rs56270790      
rs59323124       rs61736613       rs61921795       rs71068200       rs71068201       rs73313188       rs73313191       rs73313197       rs74089888       rs74089889       rs74089890       rs74521594       rs74568890       rs74872371       rs75018946       rs75240584       rs76230106       rs76440463       rs77538854       rs77797230       rs78054138       rs78563336       rs79516155       rs80157375       rs111372546       rs111518456       rs111916365       rs112208816       rs112226681       rs113274515       rs113381644       rs113823335       rs113899846       rs114026499       rs114089032       rs114282017       rs114363892       rs114767687       rs115623661       rs115789957       rs117077147       rs117288890       rs117669012       rs117846896       rs138309212       rs138685629       rs139565047       rs139697680       rs140291984       rs140525985       rs141237178       rs141240544       rs141463318       rs142018836       rs142098442       rs142721646       rs142908535       rs143618403       rs143816404       rs144295570       rs144307645       rs144577446       rs144732089       rs144994922       rs145286955       rs145731630       rs146010508       rs146096084       rs146135531       rs146854412       rs147150226       rs147500259       rs147555805       rs148087509       rs148405951       rs148638675       rs148984909       rs149441330       rs150485235       rs150694870       rs151083984       rs151312031       rs180800157       rs180933959       rs181552044       rs181729278       rs181800599       rs182192382       rs182215420       rs183467932       rs183520758       rs183548118       rs183589219       rs183631843       rs184131116       rs184938374       rs185550314       rs185812647       rs185926586       rs186242640       rs186396434       rs186474589       rs186620932       rs186824130       rs188336252       rs188469321       rs188868870       rs188993995       rs189355050       rs189641225       rs189986609       rs190134994       rs190411608       rs190442102       rs190540502       rs191205734       rs191302926       rs191381101       rs191426338       rs191740078       rs192080616       rs192153782       rs192830708       rs192959309       rs199717526       rs199869895       rs200139629       rs200260675       rs200362917       rs200383737       rs200427348       rs200476091       rs200694174       rs200758418       rs200862396       rs201035626       rs201443964       rs201594434       rs201730816       rs202043439       rs202121790       rs367798571       rs368652455       rs369084398       rs369651058       rs370201010       rs370246768       rs371058976       rs371507600       rs372116179       rs372813456       rs373295522       rs374393340       rs374677327       rs374923300       rs375750909       rs375989766       rs376534127       rs377593989       rs527654115       rs527690942       rs528018600       rs528239386       rs528275436       rs529055785       rs529363335       rs529399979       rs529628196       rs529663789       rs529857999       rs529860691       rs529935955       rs530242631       rs530500367       rs530578575       rs530933624       rs531429089       rs531472033       rs531577496       rs531882590       rs532063656       rs532108292       rs532234318       rs532324546       rs532334840       rs532429929       rs532535463       rs533367049       rs534114681       rs534355918       rs534440794       rs534488512       rs534526216       rs534653344       rs534786361       rs534821883       rs535021715       rs535186580       rs535197851       rs535222680       rs535443250       rs536100834       rs536137632       rs536392045       rs536737464       rs536770209       rs537138963       rs537349355       rs538121014       rs538155478       rs538164319       rs538397473       rs538405644       rs538927857       rs539135953       rs539172695       rs539771023       rs539808672       rs540139208       rs540465320       rs540716140       rs540787767       rs540872639       rs541070068       rs541104824       rs541147610       rs541309145       rs541341577       rs541688247       rs541768546       rs541857698       rs542107915       rs542736788       rs543480744       rs543524107       rs543688931       rs543719901       rs543723007       rs544108362       rs544347113       rs544464973       rs544927822       rs545179599       rs545349272       rs545460203       rs545495143       rs545535683       rs545672450       rs545711033       rs545711072       rs546370394       rs546700939       rs546785610       rs547631173       rs547683198       rs547958793       rs548022112       rs548281243       rs548442837       rs548736966       rs548775721       rs549072170       rs549262330       rs549386109       rs549423310       rs549625757       rs549845304       rs549883778       rs550004622       rs550099853       rs550103951       rs550182029       rs550261989       rs550992068       rs551029934       rs551033651       rs551163389       rs551884357       rs551926154       rs551996288       rs552033471       rs552105552       rs552128385       rs552181831       rs552604552       rs552882440       rs553024993       rs553311752       rs553588814       rs553927426       rs554574256       rs554730610       rs555048536       rs555339186       rs555376134       rs555381316       rs555994152       rs556030838       rs556383457       rs556420200       rs556568965       rs556608172       rs556721790       rs556987663       rs557325987       rs557400411       rs557595078       rs557635612       rs557767956       rs558378436       rs558420895       rs558461578       rs558496882       rs558583368       rs558593733       rs558786915       rs559113517       rs559290833       rs559456349       rs559553203       rs560272968       rs560393172       rs560495959       rs560532701       rs560777810       rs560916042       rs561359139       rs561982768       rs562162039       rs562891805       rs562937334       rs562958870       rs563121196       rs563196923       rs563286099       rs563734008       rs563996173       rs564000423       rs564884888       rs564931749       rs565754932       rs565787762       rs565847774       rs565925692       rs566083946       rs566479261       rs566857089       rs566967644       rs567130173       rs567218746       rs567249079       rs567270371       rs567704206       rs567738826       rs567781688       rs567903825       rs567963285       rs568234180       rs568374738       rs568423103       rs568524865       rs568773164       rs569258430       rs569805324       rs569816758       rs570297057       rs570337679       rs570520979       rs570765932       rs571235535       rs571433376       rs571490272       rs571526534       rs571612814       rs571616879       rs572480978       rs572545043       rs573452471       rs573490748       rs573726119       rs573764348       rs573890653       rs574155713       rs574426837       rs574490088       rs574509271       rs574516435       rs574868289       rs574940018       rs574980836       rs575071936       rs575142260       rs575882456       rs575915974       rs576237097       rs576392043       rs576505256       rs576740106       rs576798092       rs577158938       rs577372679       rs577884258       rs577923293       rs746073698       rs746274640       rs746978633       rs747214600       rs747377713       rs747794723       rs748395179       rs749261491       rs749774424       rs749797582       rs750024894       rs750132624       rs750347742       rs751242313       rs751262560       rs752213049       rs752407433       rs752847213       rs752965962       rs753193612       rs753211992       rs753924760       rs754192842       rs754482979       rs755466327       rs755689517       rs755990418       rs756477892       rs756503013       rs756893125       rs757013916       rs757138274       rs757948540       rs758073273       rs758278316       rs758850699       rs759420807       rs759457160       rs759954812       rs760440415       rs761024445       rs761405003       rs761472061       rs761655147       rs761693320       rs761958008       rs762610633       rs762837267       rs762991519       rs763026260       rs763888269       rs763969646       rs764263179       rs764671940       rs764735870       rs765056816       rs765400909       rs765585868       rs765601651       rs766189183       rs766272049       rs766957178       rs767242025       rs767298048       rs768146677       rs768294867       rs768343504       rs768624753       rs768676417       rs768769275       rs769716268       rs769891934       rs770006440       rs770158000       rs770642032       rs771141589       rs771424142       rs772244315       rs772493927       rs772945356       rs773394341       rs773395635       rs773485388       rs773836609       rs774357870       rs774503554       rs775380956       rs775544979       rs775634833       rs776432961       rs776708657       rs777251208       rs777768728       rs777858592       rs778234830       rs778998070       rs779640921       rs779937440       rs780484154       rs780711773       rs781157605       rs781534587       rs781639621       rs781712804      

基因表达

基因表达

HOXC6基因在不同组织中的表达：    [UniProt]

基因在不同组织中的表达图

基因引物

基因引物

正向引物序列
正向引物Tm值
反向引物序列
反向引物Tm值
rank
AGCGAATGAATTCGCACAG
59
GTACCGCGAGTAGATCTGG
60
GATTGGACCAAACCAGAGG
58
GAACACGACATTCTCCTTCTC
59
AATGAATTCGCACAGTGGG
58
CTTCTCCAGTTCCAGGGTC
59
AGCGAATGAATTCGCACAG
59
GTACCGCGAGTAGATCTGG
60
ATTGGACCAAACCAGAGGG
60
GAACACGACATTCTCCTTCTC
59
CGAATGAATTCGCACAGTG
58
GTACCGCGAGTAGATCTGG
60
AATGAATTCGCACAGTGGG
58
GGTACCGCGAGTAGATCTG
59
CTAACAGAAACGCCAGGAG
58
TTGTCTGCAGTTTGAGAGC
58
CGAATGAATTCGCACAGTG
58
GGTACCGCGAGTAGATCTG
60
AATGAATTCGCACAGTGGG
58
GTACCGCGAGTAGATCTGG
59

转录因子

转录因子

转录因子
影响类型
PubMed链接
IGFBP3
Repression
15637592
MME
Repression
15637592

基因本体信息

HOXC6基因（以及对应的蛋白质）的细胞分布位置：

[UniProt]     [GenomeNet]

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • 溶酶体
  • 内涵体
  • 细胞核
  • 细胞质
  • 液泡
  • 细胞膜
  • 细胞外基质
  • 内质网
  • 线粒体
  • 高尔基体
  • 细胞骨架

HOXC6基因的本体（GO）信息：

GO库代码
对应的蛋白质
来源代码
GO:0003677
D6RBH4(UniProtKB)
IEA
GO:0003700
D6RBH4(UniProtKB)
IEA
GO:0006355
D6RBH4(UniProtKB)
IEA
GO:0003677
D6RC34(UniProtKB)
IEA
GO:0003700
D6RC34(UniProtKB)
IEA
GO:0006355
D6RC34(UniProtKB)
IEA
GO:0003700
P09630(UniProtKB)
IEA
GO:0003714
P09630(UniProtKB)
TAS
GO:0005654
P09630(UniProtKB)
IDA
GO:0005737
P09630(UniProtKB)
IDA
GO:0006351
P09630(UniProtKB)
IEA
GO:0006357
P09630(UniProtKB)
TAS
GO:0007275
P09630(UniProtKB)
TAS
GO:0009952
P09630(UniProtKB)
IEA
GO:0043565
P09630(UniProtKB)
IEA
GO:0048706
P09630(UniProtKB)
IEA
GO:1903507
P09630(UniProtKB)
IEA

基因相互作用关系

基因相互作用关系

基因与其他基因之间的相互作用关系图
序号 作用方式 资源库来源/分值 基因名称 基因名称

基因相关microRNA

基因相关microRNA

可能调控HOXC6基因的相关microRNA：     

基因通路图

基因通路图

基因的通路属性图
通路基因列表

基因相关疾病

基因相关疾病

疾病名称 关系值 NofPmids NofSnps 来源
疾病名称 关系值 NofPmids NofSnps 来源
Neuroblastoma 0.002995792 2 0 BeFree_LHGDN
Malignant neoplasm of prostate 0.001357209 5 0 BeFree
Prostate carcinoma 0.001357209 5 0 BeFree
Malignant neoplasm of breast 0.000542884 2 0 BeFree
leukemia 0.000542884 2 0 BeFree
Carcinogenesis 0.000542884 2 0 BeFree
Breast Carcinoma 0.000542884 2 0 BeFree
Carcinoid Tumor 0.000271442 1 0 BeFree
Hydatidiform Mole 0.000271442 1 0 BeFree
Lymphoma 0.000271442 1 0 BeFree
Neoplasm Metastasis 0.000271442 1 0 BeFree
Ovarian Carcinoma 0.000271442 1 0 BeFree
Tumor Progression 0.000271442 1 0 BeFree
Ki-1+ Anaplastic Large Cell Lymphoma 0.000271442 1 0 BeFree
Carcinoid tumor no ICD-O subtype 0.000271442 1 0 BeFree
Epithelial ovarian cancer 0.000271442 1 0 BeFree
Central neuroblastoma 0.000271442 1 0 BeFree
Dissecting aneurysm of the thoracic aorta 0.000271442 1 0 BeFree
Malignant neoplasm of ovary 0.000271442 1 0 BeFree
Cutaneous lymphoma 0.000271442 1 0 BeFree
Precursor B-cell lymphoblastic leukemia 0.000271442 1 0 BeFree
Benign Prostatic Hyperplasia 0.000271442 1 0 BeFree

基因相关文献

基因相关文献

基因相关服务

基因相关服务

基因评论

基因评论

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