HNRNPDL(heterogeneous nuclear ribonucleoprotein D-like) 转至新版数据库

基因基本信息

基因基本信息

基因简称(symbol)
    [HGNC]     [GeneCards]     [NCBI]
基因种类(locus group)
同源简称(alias symbol)
基因家族代码(gene_family_id)
    [HGNC]     [GenScript]
omim代码
entrez码
    [Vega]
vega基因码
ensembl基因码
    [Ensembl]
基因家族(gene family)
refseq数据库代号

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基因种类(locus_type)
基因名称状态(status)
location_sortable
同源基因名称(alias name)
基因名称批准使用时间(date_approved_reserved)
基因简称更名时间(date_symbol_changed)
基因名称更名时间(date_name_changed)
更新时间(date_modified)
ucsc码
ena
ccds数据码
uniprot数据码
pubmed代码
mgd码
rgd码
生命科学数据库(lsdb)
更新时间(date modified)
cosmic
mirbase
基因曾用简称(prev symbol)
基因曾用名称(prev name)
homeodb
cosmic
snornabase
bioparadigms slc
orphanet
假基因信息(pseudogeneorg)
horde id
merops
imgt
iuphar
kznf基因类别
mamit-trnadb
cd
LncRNA数据库
酶代码
中间纤维数据库

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基因染色体位置

基因染色体位置

4q21.22
基因染色体位置图

基因简述

基因简述

This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two RRM domains that bind to RNAs. Three alternatively spliced transcript variants have been described for this gene. One of the variants is probably not translated because the transcript is a candidate for nonsense-mediated mRNA decay. The protein isoforms encoded by this gene are similar to its family member HNRPD. [provided by RefSeq, May 2011]

[中文简述(自动翻译):]  该基??因属于普遍表达的异构核核糖核蛋白（hnRNPs）的亚科。该hnRNPs是RNA结合蛋白和它们复杂的异构核RNA（hnRNA）。这些蛋白与预先的mRNA在细胞核相关联，并且似乎影响mRNA的前处理和mRNA代谢和转运的其他方面。而所有hnRNPs的存在于细胞核中，一些似乎细胞核和细胞质之间穿梭。的核蛋白蛋白质具有不同核酸结合性质。由该基因编码的蛋白质具有结合于RNA的2 RRM结构域。三个可变剪接转录物变体已被用于这个基因说明。其中一个变体可能是没有翻译，因为成绩单是无义介导的mRNA降解的候选人。由该基因编码的蛋白质同种型是类似于其家族成员HNRPD。 [由RefSeq的，2011年5月提供]

OMIM数据库中对HNRNPDL基因的介绍     Wikipedia数据库中对HNRNPDL基因的介绍

基因序列

基因序列

HNRNPDL基因的碱基序列：[NCBI]

基因突变

基因突变

HNRNPDL基因的碱基突变：           显示全部snp
rs8732       rs1045250       rs2516817       rs2859538       rs3749540       rs6827156       rs10646358       rs11546516       rs11552701       rs12500801       rs28362576       rs35117197       rs35670686       rs61729823       rs61737724       rs72909811       rs75031749       rs75720045       rs75779369       rs76027722       rs76210269       rs79151332       rs79854604       rs114172590       rs115894273       rs116396124       rs140163739       rs140334420       rs140863242       rs141595181       rs145620184       rs146542214       rs147289067       rs147809606       rs147979190       rs149117436       rs149817562      
rs181320957       rs182031643       rs182848246       rs183050794       rs183805986       rs185938564       rs187021296       rs187466443       rs188034572       rs188575638       rs189841383       rs190215195       rs199543859       rs200009960       rs200018272       rs200595389       rs200673707       rs200737081       rs201715406       rs201774571       rs367651805       rs368295854       rs368496309       rs370279130       rs370634345       rs370848604       rs370944367       rs371979177       rs372207286       rs372895153       rs372961029       rs373042980       rs373320441       rs373740869       rs375343775       rs375464163       rs375688116       rs376324771       rs376898265       rs377010542       rs377552167       rs397811624       rs529653747       rs530194901       rs530340169       rs531086771       rs531149266       rs531745307       rs532165518       rs533983916       rs535251363       rs537262328       rs537568406       rs538044241       rs538603579       rs538665218       rs538718261       rs538744946       rs539660128       rs539919690       rs540206540       rs542223276       rs542879065       rs543826947       rs544087712       rs544551678       rs544794524       rs545817229       rs545856641       rs546568295       rs546656055       rs546993798       rs547593539       rs548143431       rs549619884       rs550196106       rs550940576       rs551094715       rs552128643       rs552202447       rs553185842       rs553856255       rs554040733       rs554048890       rs554498551       rs554867444       rs554919068       rs556247256       rs557196159       rs557384403       rs558245891       rs558392190       rs558427021       rs558448801       rs558907758       rs560213239       rs560302875       rs560994334       rs561351766       rs564773981       rs565574563       rs566256694       rs566635943       rs567282719       rs567739874       rs568345543       rs569126343       rs569127504       rs570546700       rs571789956       rs571839198       rs572541151       rs572848899       rs573943710       rs574450249       rs574496554       rs575182382       rs575873797       rs576866613       rs578111870       rs578176168       rs745336912       rs745924397       rs746022795       rs746136362       rs746207168       rs746297079       rs747150158       rs747302396       rs747779194       rs748038687       rs748227277       rs748553069       rs748859467       rs749056651       rs749421076       rs749733287       rs749962540       rs750580664       rs751611134       rs752832546       rs752922266       rs752982130       rs753174711       rs753271491       rs753527264       rs753636245       rs753846571       rs753975247       rs754208735       rs755129042       rs755148544       rs755336894       rs755493173       rs756274044       rs756584883       rs756666429       rs756961811       rs757117165       rs757439623       rs757778061       rs758689857       rs758712232       rs758895645       rs759145489       rs759302228       rs759986776       rs760242178       rs760683509       rs760730159       rs760917145       rs761016544       rs761856605       rs761873392       rs762023929       rs762213534       rs762623646       rs762730693       rs763175161       rs763348810       rs763550244       rs763589139       rs763638263       rs764190936       rs764308241       rs764382746       rs764970578       rs765008087       rs766107454       rs766115304       rs766271556       rs766972406       rs767247622       rs767281029       rs767331682       rs767819623       rs767858578       rs767979513       rs768442894       rs768531052       rs768688845       rs768730541       rs769253084       rs769311412       rs769430117       rs770246584       rs770406082       rs770762621       rs771120108       rs771211825       rs771657127       rs772003613       rs772115142       rs772139272       rs772314860       rs772790558       rs773300829       rs773326362       rs773441366       rs773462746       rs773946538       rs773982449       rs774388005       rs774469201       rs774480997       rs775002922       rs775162281       rs775253636       rs776001856       rs776397617       rs777344257       rs778302994       rs778310020       rs778420760       rs778872913       rs779169039       rs779364180       rs779472346       rs779936262       rs780331684       rs780368180       rs780496008       rs780585758       rs780878669       rs781068843       rs781169219       rs781241362       rs781616451       rs781687450       rs9316       rs13952       rs14580       rs997719       rs997720       rs997721       rs1802543       rs1802544       rs2516818       rs3172563       rs3172564       rs3217298       rs6826022       rs6848299       rs10026631       rs11552704       rs11737188       rs11932284       rs12644560       rs12650145       rs34583014       rs35028863       rs57945204       rs59154495       rs61132735       rs61729822       rs62313422       rs72909806       rs72909808       rs74563910       rs75008121       rs75269398       rs75710591       rs75767756       rs75978479       rs77885237       rs77972030       rs79373393       rs79740118       rs80094926       rs111527549       rs111799653       rs112248900       rs112392797       rs112419307       rs112774418       rs113289789       rs113676360       rs114515824       rs114786982       rs115114284       rs115245273       rs115395197       rs115585932       rs116639662       rs117839267       rs137931240       rs138288718       rs138329175       rs138358528       rs138697977       rs138891190       rs139028248       rs140163431       rs140423053       rs141031510       rs141564694       rs142868491       rs142906141       rs144376145       rs144740771       rs144818240       rs145072167       rs145639900       rs146129186       rs146329382       rs147144818       rs147577198       rs148587337       rs148883748       rs149258996       rs149415220       rs149880926       rs150384932       rs150917590       rs151020164       rs181209193       rs182206932       rs182552266       rs183105522       rs183833572       rs184232207       rs184799779       rs185521781       rs186090851       rs186725217       rs187253526       rs188226035       rs188287711       rs188817622       rs189595271       rs190403058       rs190431663       rs191244295       rs191491807       rs191930136       rs192018764       rs192696304       rs193014392       rs199536709       rs199594758       rs200123403       rs200401056       rs200481104       rs200531097       rs200748953       rs201341336       rs201756867       rs201947429       rs202086820       rs202193348       rs367614143       rs367725261       rs367896765       rs369035855       rs369580347       rs369611423       rs369680059       rs369770953       rs369943423       rs369943811       rs370573638       rs370811815       rs371250695       rs372443050       rs373443496       rs373581803       rs373781087       rs373795505       rs373828999       rs374333066       rs375152625       rs375521123       rs376313318       rs376744985       rs376907510       rs377138609       rs377281527       rs527520007       rs527706371       rs529178270       rs529730933       rs530501276       rs531237914       rs531270512       rs531671073       rs531730878       rs532030380       rs532089301       rs532153923       rs532525527       rs533470608       rs533876857       rs534835703       rs534861091       rs536468839       rs536512172       rs536600180       rs536785671       rs536792596       rs537653876       rs537798376       rs538157014       rs538979251       rs539661739       rs540060474       rs541195800       rs541843928       rs542151196       rs542418945       rs543017954       rs543029837       rs543959126       rs544135967       rs545316005       rs545987997       rs546114981       rs546580080       rs547340881       rs547522856       rs547745879       rs548338532       rs548547244       rs548803994       rs549180963       rs549268593       rs549455271       rs549987832       rs550145830       rs550939180       rs551027227       rs551179434       rs551259554       rs551269134       rs551276009       rs551556311       rs551564125       rs552205295       rs553072528       rs553724283       rs553908767       rs555968555       rs556292111       rs556460676       rs556585030       rs557634337       rs558392358       rs558576841       rs558624260       rs559526547       rs560004661       rs560144338       rs560853198       rs561581939       rs562185859       rs562254859       rs562594171       rs563429588       rs563791539       rs564386984       rs564509729       rs564594694       rs564629767       rs564773986       rs564857955       rs565763085       rs565768133       rs566242493       rs566489454       rs566956833       rs567257660       rs567721273       rs567752579       rs567877399       rs568334988       rs569016976       rs569761642       rs569921185       rs570757196       rs570769754       rs570774873       rs570881771       rs571328510       rs571683874       rs571920045       rs571977411       rs572433101       rs572522034       rs572577877       rs573040728       rs574046440       rs574184374       rs574645490       rs575063832       rs575178993       rs576074747       rs576209058       rs576525626       rs576855898       rs577161374       rs578048050       rs578132115       rs578194743       rs745680358       rs746015668       rs746188244       rs746626559       rs747085036       rs747341068       rs747467137       rs747638876       rs747726323       rs748266200       rs748273097       rs748637892       rs748771481       rs749078374       rs749371050       rs749371373       rs749514643       rs749647461       rs749964166       rs750052144       rs750431961       rs751065243       rs751511505       rs751792376       rs751971549       rs752333956       rs752417076       rs752641164       rs752710041       rs753086595       rs753414374       rs753504406       rs753619730       rs753638171       rs754247599       rs754594924       rs754927537       rs755056939       rs755291408       rs755534957       rs755573198       rs755637495       rs755758174       rs755848901       rs756525949       rs756546059       rs756764218       rs756875958       rs756928524       rs757487918       rs757576538       rs757611684       rs757774444       rs757967866       rs758100589       rs758290418       rs758601965       rs758733851       rs759055793       rs759441262       rs759514374       rs759697176       rs759786788       rs760313332       rs760634346       rs760730095       rs760890303       rs760992923       rs761873280       rs762011185       rs762453426       rs762663619       rs762712744       rs762882360       rs763111203       rs763497821       rs763585474       rs763739966       rs763769752       rs763843229       rs764221541       rs764701660       rs764921476       rs764962973       rs765131639       rs765640758       rs765842262       rs765941766       rs766007994       rs766145966       rs766379048       rs766427755       rs766658220       rs766699785       rs766844667       rs767084004       rs767177978       rs767472810       rs767585018       rs767608517       rs767819688       rs768190099       rs768281792       rs768295689       rs768772036       rs769273103       rs769612628       rs769784067       rs769989101       rs770156107       rs770505111       rs770701262       rs770980485       rs771124077       rs771466422       rs771727801       rs771764838       rs772467150       rs772841258       rs772969505       rs773168380       rs773185365       rs773322956       rs773339945       rs773387280       rs773877988       rs774213776       rs774491044       rs774566973       rs774793803       rs775047316       rs775087317       rs775353405       rs775577778       rs776021128       rs776278860       rs776715771       rs776760012       rs776882102       rs777179119       rs777282036       rs777907484       rs778112535       rs778144589       rs778234675       rs778331553       rs778497871       rs778804511       rs779161443       rs779361183       rs779448092       rs780049329       rs780460094       rs780792520       rs780959902       rs781011955       rs781073121       rs781542699       rs781625067       rs781669787      

基因表达

基因表达

HNRNPDL基因在不同组织中的表达：    [UniProt]

基因在不同组织中的表达图

基因引物

基因引物

正向引物序列
正向引物Tm值
反向引物序列
反向引物Tm值
rank
ACATATACTGATGAAGAGCCAG
58
CTTTGATTTCACACTTCCCAG
58
CACATATACTGATGAAGAGCCA
58
CTTTGATTTCACACTTCCCAG
58
TCACATATACTGATGAAGAGCC
58
CTTTGATTTCACACTTCCCAG
58

转录因子

转录因子

      尚未收录相关数据

基因本体信息

HNRNPDL基因（以及对应的蛋白质）的细胞分布位置：

[UniProt]     [GenomeNet]

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • 溶酶体
  • 内涵体
  • 细胞核
  • 细胞质
  • 液泡
  • 细胞膜
  • 细胞外基质
  • 内质网
  • 线粒体
  • 高尔基体
  • 细胞骨架

HNRNPDL基因的本体（GO）信息：

GO库代码
对应的蛋白质
来源代码
GO:0000166
A0A087WUK2(UniProtKB)
IEA
GO:0003676
A0A087WUK2(UniProtKB)
IEA
GO:0019013
A0A087WUK2(UniProtKB)
IEA
GO:0030529
A0A087WUK2(UniProtKB)
IEA
GO:0000166
O14979(UniProtKB)
IEA
GO:0003677
O14979(UniProtKB)
IEA
GO:0003690
O14979(UniProtKB)
IDA
GO:0003697
O14979(UniProtKB)
IDA
GO:0005515
O14979(UniProtKB)
IPI
GO:0005634
O14979(UniProtKB)
IDA
GO:0005654
O14979(UniProtKB)
IDA
GO:0005681
O14979(UniProtKB)
NAS
GO:0005737
O14979(UniProtKB)
IEA
GO:0006351
O14979(UniProtKB)
IEA
GO:0006355
O14979(UniProtKB)
IEA
GO:0006396
O14979(UniProtKB)
NAS
GO:0008143
O14979(UniProtKB)
IDA
GO:0010468
O14979(UniProtKB)
IDA
GO:0034046
O14979(UniProtKB)
IDA
GO:0044822
O14979(UniProtKB)
IDA
GO:0044822
O14979(UniProtKB)
IDA
GO:0070062
O14979(UniProtKB)
IDA

基因相互作用关系

基因相互作用关系

基因与其他基因之间的相互作用关系图
序号 作用方式 资源库来源/分值 基因名称 基因名称

基因相关microRNA

基因相关microRNA

可能调控HNRNPDL基因的相关microRNA：     

基因通路图

基因通路图

基因的通路属性图
通路基因列表

基因相关疾病

基因相关疾病

疾病名称 关系值 NofPmids NofSnps 来源
疾病名称 关系值 NofPmids NofSnps 来源
LIMB-GIRDLE MUSCULAR DYSTROPHY, TYPE 1G (disorder) 0.36 1 1 CLINVAR_ORPHANET_UNIPROT
Malignant neoplasm of breast 0.002367032 1 0 GAD
Malignant neoplasm of lung 0.001628651 6 0 BeFree
Carcinoma of lung 0.001628651 6 0 BeFree
Non-Small Cell Lung Carcinoma 0.000542884 2 0 BeFree
HIV Infections 0.000542884 2 0 BeFree
Muscular Dystrophies, Limb-Girdle 0.000542884 2 0 BeFree
Liver carcinoma 0.000542884 2 0 BeFree
Amyotrophic Lateral Sclerosis 0.000271442 1 0 BeFree
Rheumatoid Arthritis 0.000271442 1 0 BeFree
Herpes Simplex Infections 0.000271442 1 0 BeFree
Angioimmunoblastic Lymphadenopathy 0.000271442 1 0 BeFree
Intestinal Neoplasms 0.000271442 1 0 BeFree
Adult T-Cell Lymphoma/Leukemia 0.000271442 1 0 BeFree
Lupus Erythematosus, Systemic 0.000271442 1 0 BeFree
Mixed Connective Tissue Disease 0.000271442 1 0 BeFree
Myotonic Dystrophy 0.000271442 1 0 BeFree
Neuroblastoma 0.000271442 1 0 BeFree
Schizophrenia 0.000271442 1 0 BeFree
T-Cell Lymphoma 0.000271442 1 0 BeFree
Liver and Intrahepatic Biliary Tract Carcinoma 0.000271442 1 0 BeFree
Malignant neoplasm of liver 0.000271442 1 0 BeFree
Malignant neoplasm of pancreas 0.000271442 1 0 BeFree
Malignant neoplasm of prostate 0.000271442 1 0 BeFree
Congenital Myotonic Dystrophy 0.000271442 1 0 BeFree
Prostate carcinoma 0.000271442 1 0 BeFree
invasive cancer 0.000271442 1 0 BeFree
Central neuroblastoma 0.000271442 1 0 BeFree

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