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The protein encoded by this gene is involved in cell motility. It is expressed in breast tissue and together with other proteins, it forms a complex with BRCA1 and BRCA2, thus is potentially associated with higher risk of breast cancer. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Dec 2008]
[中文简述(自动翻译):]  由该基因编码的蛋白质是参与细胞运动。它是乳房组织中表达,并与其它蛋白质,它形成与BRCA1和BRCA2的复合物,从而潜在地与患乳腺癌的风险增加有关。编码不同亚型选择性剪接转录变异体已经注意到了这个基因。 [由RefSeq的,2008年12月提供]
HMMR基因(以及对应的蛋白质)的细胞分布位置:
HMMR基因的本体(GO)信息:
疾病名称 | 关系值 | NofPmids | NofSnps | 来源 |
Mammary Neoplasms | 0.125720142 | 3 | 0 | BeFree_CTD_human_LHGDN |
Myeloid Leukemia, Chronic | 0.123267234 | 2 | 0 | BeFree_CTD_human_LHGDN |
IGA Glomerulonephritis | 0.12 | 1 | 0 | CTD_human |
Peripheral Neuropathy | 0.12 | 1 | 0 | CTD_human |
Polycystic Ovary Syndrome | 0.12 | 1 | 0 | CTD_human |
Neoplasm Metastasis | 0.004895885 | 9 | 0 | BeFree_LHGDN |
Malignant neoplasm of breast | 0.003995683 | 6 | 0 | BeFree_GAD |
leukemia | 0.003267234 | 3 | 0 | BeFree_LHGDN |
Squamous cell carcinoma | 0.002995792 | 2 | 0 | BeFree_LHGDN |
Colorectal Neoplasms | 0.00272435 | 1 | 0 | LHGDN |
Endometrial Neoplasms | 0.00272435 | 1 | 0 | LHGDN |
Glioma | 0.00272435 | 1 | 0 | LHGDN |
Prostatic Neoplasms | 0.00272435 | 1 | 0 | LHGDN |
Multiple Myeloma | 0.001900093 | 7 | 0 | BeFree |
Leukemia, Myelocytic, Acute | 0.001628651 | 6 | 0 | BeFree |
Breast Carcinoma | 0.001628651 | 6 | 0 | BeFree |
Chronic Lymphocytic Leukemia | 0.001085767 | 4 | 0 | BeFree |
Malignant neoplasm of prostate | 0.000814326 | 3 | 0 | BeFree |
Prostate carcinoma | 0.000814326 | 3 | 0 | BeFree |
Malignant tumor of colon | 0.000542884 | 2 | 0 | BeFree |
Tumor Progression | 0.000542884 | 2 | 0 | BeFree |
Colon Carcinoma | 0.000542884 | 2 | 0 | BeFree |
Astrocytoma | 0.000271442 | 1 | 0 | BeFree |
Malignant neoplasm of urinary bladder | 0.000271442 | 1 | 0 | BeFree |
Blast Phase | 0.000271442 | 1 | 0 | BeFree |
Colorectal Carcinoma | 0.000271442 | 1 | 0 | BeFree |
Crohn Disease | 0.000271442 | 1 | 0 | BeFree |
Glioblastoma | 0.000271442 | 1 | 0 | BeFree |
Acute lymphocytic leukemia | 0.000271442 | 1 | 0 | BeFree |
Lymphoma | 0.000271442 | 1 | 0 | BeFree |
Malignant neoplasm of stomach | 0.000271442 | 1 | 0 | BeFree |
B-Cell Lymphomas | 0.000271442 | 1 | 0 | BeFree |
Diffuse Large B-Cell Lymphoma | 0.000271442 | 1 | 0 | BeFree |
Pancreatic carcinoma | 0.000271442 | 1 | 0 | BeFree |
Adenocarcinoma of pancreas | 0.000271442 | 1 | 0 | BeFree |
Malignant neoplasm of pancreas | 0.000271442 | 1 | 0 | BeFree |
Carcinogenesis | 0.000271442 | 1 | 0 | BeFree |
Stomach Carcinoma | 0.000271442 | 1 | 0 | BeFree |
Carcinoma of bladder | 0.000271442 | 1 | 0 | BeFree |
5q-syndrome | 0.000271442 | 1 | 0 | BeFree |
Malignant Peripheral Nerve Sheath Tumor | 0.000271442 | 1 | 0 | BeFree |
Hurthle Cell Tumor | 0.000271442 | 1 | 0 | BeFree |
Chronic leukemia (category) | 0.000271442 | 1 | 0 | BeFree |
Myelodysplastic Syndrome with Isolated del(5q) | 0.000271442 | 1 | 0 | BeFree |
Autoimmune Lymphoproliferative Syndrome | 0.000271442 | 1 | 0 | BeFree |
Sporadic Breast Carcinoma | 0.000271442 | 1 | 0 | BeFree |
Oncocytic Neoplasm | 0.000271442 | 1 | 0 | BeFree |
Oxyphilic Adenoma | 0.000271442 | 1 | 0 | BeFree |
Colorectal Cancer | 0.000271442 | 1 | 0 | BeFree |
Neoplasms, Intracranial | 0.000271442 | 1 | 0 | BeFree |
Benign Prostatic Hyperplasia | 0.000271442 | 1 | 0 | BeFree |
Non-Neoplastic Disorder | 0.000271442 | 1 | 0 | BeFree |
Chromosome 5, trisomy 5q | 0.000271442 | 1 | 0 | BeFree |
Clear-cell metastatic renal cell carcinoma | 0.000271442 | 1 | 0 | BeFree |
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