HLA-DRB3基因详情-基因数据库-基因云馆

HLA-DRB3(major histocompatibility complex, class II, DR beta 3)

基因简称(symbol)

HLA-DRB3 [HGNC] [GeneCards] [NCBI]

基因种类(locus group)

protein-coding gene

同源简称(alias symbol)

基因家族代码(gene_family_id)

588|591 [HGNC] [GenScript]

omim代码

612735

entrez码

3125 [Vega]

vega基因码

OTTHUMG00000012609

ensembl基因码

ENSG00000196101 [Ensembl]

基因家族(gene family)

Histocompatibility complex|C1-set domain containing

refseq数据库代号

NM_022555

更多...

基因种类(locus_type)

gene with protein product

基因名称状态(status)

Approved

location_sortable

06p21.3 alternate reference locus

同源基因名称(alias name)

基因名称批准使用时间(date_approved_reserved)

2001-06-22T00:00:00Z

基因简称更名时间(date_symbol_changed)

基因名称更名时间(date_name_changed)

更新时间(date_modified)

2014-01-23T00:00:00Z

ucsc码

uc011fni.1

ena

BC008987|GL000250|GL000251|GL000255

ccds数据码

uniprot数据码

P79483

pubmed代码

mgd码

rgd码

生命科学数据库(lsdb)

IMGT/HLA Database|http://www.ebi.ac.uk/imgt/hla/

更新时间(date modified)

2014-01-23T00:00:00Z

cosmic

mirbase

基因曾用简称(prev symbol)

HLA-DR3B

基因曾用名称(prev name)

homeodb

cosmic

snornabase

bioparadigms slc

orphanet

假基因信息(pseudogeneorg)

horde id

merops

imgt

iuphar

kznf基因类别

mamit-trnadb

cd

LncRNA数据库

酶代码

中间纤维数据库

收起

6p21.3 alternate reference locus

HLA-DRB3 belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DRA) and a beta (DRB) chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. Within the DR molecule the beta chain contains all the polymorphisms specifying the peptide binding specificities. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. DRB1 is expressed at a level five times higher than its paralogues DRB3, DRB4 and DRB5. The presence of DRB3 is linked with allelic variants of DRB1, otherwise it is omitted. There are 4 related pseudogenes: DRB2, DRB6, DRB7, DRB8 and DRB9. [provided by RefSeq, Jul 2008]

[中文简述(自动翻译):] HLA-DRB3属于HLA II类β链旁系同源基??因。此Ⅱ类分子是选自由α（DRA）和β（DRB）链，无论在膜锚定的异源二聚体。它起着通过呈现由胞外蛋白衍生的肽在免疫系统中发挥中心作用。（：B淋巴细胞，树突细胞，巨噬细胞，APC）II类分子在抗原呈递细胞中表达。的β链为约26-28 kDa和其基因含有6个外显子。外显子1编码前导肽，外显子2和3编码的两个细胞外结构域，外显子4编码的跨膜结构域和外显子5编码胞质尾区。在DR分子的β链包含了所有的多态性指定肽结合特异性。打字这些多态性是经常的骨髓和肾移植完成。 DRB1是在表达水平低于其旁系同源DRB3，DRB4和DRB5的5倍。 DRB3的存在与DRB1的等位基因变体相连，否则，它被删去。有4个相关的假：DRB2，DRB6，DRB7，DRB8和DRB9。 [由RefSeq的，2008年7月提供]

OMIM数据库中对HLA-DRB3基因的介绍 Wikipedia数据库中对HLA-DRB3基因的介绍

HLA-DRB3基因的碱基序列：[NCBI]

HLA-DRB3基因的碱基突变：显示全部snp

rs696318 rs696318 rs701884 rs701884 rs707956 rs707956 rs1059350 rs1059350 rs1059576 rs1059576 rs1059580 rs1059580 rs1059598 rs1059598 rs1059633 rs1059633 rs1059643 rs1059643 rs1064587 rs1064587 rs1064594 rs1064594 rs1064595 rs1064595 rs1064677 rs1064677 rs1071747 rs1071747 rs1071748 rs1071748 rs1071751 rs1071751 rs1071759 rs1071759 rs1136633 rs1136633 rs1136744

rs1136752 rs1136752 rs1136757 rs1136757 rs1136760 rs1136760 rs1136762 rs1136762 rs1136778 rs1136778 rs1136787 rs1136787 rs1136905 rs1136905 rs1137361 rs1137361 rs1137470 rs1137470 rs1137496 rs1137496 rs1137498 rs1137498 rs1141741 rs1141741 rs1141742 rs1141742 rs1141743 rs1141743 rs1141755 rs1141755 rs1141867 rs1141867 rs1141879 rs1141879 rs1987529 rs2157337 rs2157337 rs2187821 rs2187821 rs2213582 rs2213583 rs2213583 rs2894266 rs3179203 rs3179203 rs3828826 rs3828826 rs4484563 rs4484563 rs4492228 rs4492228 rs4504496 rs4601179 rs4601179 rs4637671 rs5000805 rs5000806 rs5000807 rs6899600 rs6920165 rs6935811 rs6935811 rs7766539 rs7766539 rs7766884 rs7767208 rs7771451 rs7771451 rs7771596 rs7771596 rs7771747 rs10947296 rs11751340 rs11752108 rs11752108 rs11752112 rs11752123 rs11752123 rs11755958 rs11755986 rs11755986 rs11963860 rs11963860 rs11965262 rs11965298 rs11965298 rs11966146 rs11966146 rs11967891 rs11967891 rs11970219 rs12661008 rs12661008 rs12662539 rs12665160 rs13213784 rs13213784 rs16870187 rs16870187 rs16870189 rs16870189 rs16870192 rs16870192 rs16870194 rs16870194 rs16870195 rs16870195 rs17204294 rs17204294 rs17210637 rs17210637 rs17211043 rs17211043 rs17405212 rs17405212 rs17433849 rs17433849 rs17850459 rs17850459 rs34265294 rs34265294 rs34267617 rs34267617 rs34328528 rs34328528 rs34358983 rs34358983 rs34413716 rs34413716 rs34888859 rs34888859 rs35190736 rs35190736 rs35209896 rs35209896 rs35231986 rs35231986 rs35262198 rs35262198 rs35273488 rs35273488 rs35321667 rs35321667 rs35507994 rs35507994 rs35556553 rs35556553 rs35641438 rs35641438 rs35739325 rs35739325 rs35747774 rs35747774 rs35838968 rs35838968 rs36153736 rs36153736 rs36165851 rs36165851 rs36194033 rs36194033 rs41541115 rs41541115 rs41541218 rs41541218 rs41544215 rs41544215 rs41545413 rs41545413 rs41546317 rs41546317 rs41547217 rs41547217 rs41548618 rs41548618 rs41550412 rs41550412 rs41551116 rs41551116 rs41553512 rs41553512 rs41554620 rs41554620 rs41556512 rs41556512 rs41556615 rs41556615 rs41559420 rs41559420 rs41559714 rs41559714 rs41559913 rs41559913 rs41562816 rs41562816 rs57196859 rs57196859 rs57343668 rs57343668 rs57818883 rs57818883 rs58427731 rs58427731 rs58660424 rs58660424 rs59117905 rs59117905 rs60378094 rs60378094 rs61146035 rs61146035 rs61433897 rs61433897 rs62405576 rs62405576 rs62405577 rs62405577 rs62405578 rs62405578 rs62405579 rs62405579 rs66493060 rs66493060 rs66512233 rs66512233 rs66969006 rs66969006 rs67449961 rs67449961 rs67456882 rs67456882 rs67515058 rs67515058 rs67538106 rs67538106 rs67588672 rs67588672 rs67598791 rs67598791 rs67756215 rs67756215 rs67773077 rs67773077 rs67851010 rs67851010 rs67987819 rs67987819 rs68142406 rs68142406 rs71547391 rs71547391 rs71549215 rs71549215 rs71549216 rs71549216 rs71549217 rs71549217 rs71549218 rs71549218 rs71549219 rs71549219 rs71549220 rs71549220 rs71549223 rs71549223 rs71549224 rs71549224 rs71549226 rs71549226 rs71549248 rs71549248 rs72508426 rs72508426 rs72508427 rs72508427 rs72508428 rs72508428 rs72508429 rs72508429 rs72508430 rs72508430 rs72508431 rs72508431 rs72508432 rs72508432 rs72508433 rs72508433 rs72508434 rs72508434 rs72508435 rs72508435 rs72508436 rs72508436 rs72508437 rs72508437 rs72508440 rs72508440 rs72508441 rs72508441 rs72508442 rs72508442 rs72508443 rs72508443 rs72508444 rs72508444 rs72508445 rs72508445 rs72508446 rs72508446 rs72508447 rs72508447 rs72508448 rs72508448 rs72508449 rs72508449 rs72508450 rs72508450 rs72508451 rs72508451 rs72508452 rs72508452 rs72508453 rs72508453 rs72508454 rs72508454 rs72508455 rs72508455 rs72508456 rs72508456 rs72508457 rs72508457 rs72508462 rs72508462 rs72849295 rs72849295 rs72851011 rs72851011 rs72851016 rs72851016 rs72851017 rs72851017 rs72851018 rs72851018 rs72851020 rs72851020 rs72851021 rs72851021 rs72851022 rs72851022 rs72851025 rs72851025 rs73405151 rs73405151 rs73405168 rs73405168 rs73405196 rs73405196 rs73405198 rs73405198 rs73407203 rs73407203 rs73407207 rs73407207 rs73407208 rs73407208 rs73407211 rs73407211 rs73407285 rs73407285 rs73407287 rs73407287 rs73726156 rs73726156 rs73726163 rs73726163 rs73726164 rs73726164 rs73726165 rs73726165 rs73726168 rs73726168 rs73726170 rs73726170 rs73726175 rs73726175 rs73726176 rs73726176 rs73726177 rs73726177 rs73726178 rs73726178 rs73726180 rs73726180 rs73726181 rs73726181 rs73726182 rs73726182 rs73726183 rs73726183 rs73726184 rs73726184 rs73726187 rs73726187 rs73726188 rs73726188 rs73726189 rs73726189 rs73726192 rs73726192 rs73726194 rs73726194 rs73726196 rs73726196 rs73726198 rs73726198 rs73726199 rs73726199 rs73726200 rs73726200 rs73726202 rs73726202 rs73727907 rs73727907 rs73727909 rs73727909 rs73727912 rs73727912 rs73727913 rs73727913 rs73727915 rs73727915 rs73727916 rs73727916 rs73727917 rs73727917 rs73727918 rs73727918 rs73727923 rs73727923 rs73727927 rs73727927 rs73729758 rs73729758 rs73729759 rs73729759 rs74196779 rs74196779 rs74198961 rs74198961 rs74203767 rs74203767 rs74205903 rs74205903 rs74216018 rs74216018 rs74223613 rs74223613 rs74223623 rs74223623 rs74290585 rs74290585 rs74290586 rs74290586 rs74330372 rs74330372 rs74333782 rs74333782 rs74485644 rs74485644 rs74516594 rs74516594 rs74655967 rs74655967 rs74738572 rs74738572 rs74789424 rs74789424 rs74791653 rs74791653 rs74870936 rs74870936 rs74916446 rs74916446 rs74943410 rs74943410 rs74948575 rs74948575 rs75224370 rs75224370 rs75244979 rs75244979 rs75269267 rs75269267 rs75375694 rs75375694 rs75457801 rs75457801 rs75469638 rs75469638 rs75540255 rs75540255 rs75563047 rs75563047 rs75654131 rs75654131 rs75673933 rs75673933 rs75709987 rs75709987 rs75793795 rs75793795 rs75813865 rs75813865 rs75887920 rs75887920 rs75901433 rs75901433 rs75906455 rs75906455 rs75979302 rs75979302 rs75983593 rs75983593 rs76035945 rs76035945 rs76070957 rs76070957 rs76155697 rs76155697 rs76192666 rs76192666 rs76209082 rs76209082 rs76270534 rs76270534 rs76302731 rs76302731 rs76312591 rs76312591 rs76415507 rs76415507 rs76450288 rs76450288 rs76468221 rs76468221 rs76515922 rs76515922 rs76562035 rs76562035 rs76564302 rs76564302 rs76580792 rs76580792 rs76583860 rs76583860 rs76680145 rs76680145 rs76704763 rs76704763 rs76747582 rs76747582 rs76748970 rs76748970 rs76753104 rs76753104 rs76784864 rs76784864 rs76792006 rs76792006 rs76816118 rs76816118 rs76817401 rs76817401 rs76851429 rs76851429 rs76918408 rs76918408 rs76939305 rs76939305 rs76949882 rs76949882 rs76995658 rs76995658 rs77024756 rs77024756 rs77052909 rs77052909 rs77063554 rs77063554 rs77149458 rs77149458 rs77154604 rs77154604 rs77159841 rs77159841 rs77180119 rs77180119 rs77226719 rs77226719 rs77258208 rs77258208 rs77335463 rs77335463 rs77540002 rs77540002 rs77594561 rs77594561 rs77604461 rs77604461 rs77624723 rs77624723 rs77691050 rs77691050 rs77762669 rs77762669 rs77866376 rs77866376 rs77867566 rs77867566 rs77936321 rs77936321 rs77951594 rs77951594 rs77963273 rs77963273 rs78097306 rs78097306 rs78098131 rs78098131 rs78135308 rs78135308 rs78247055 rs78247055 rs78250111 rs78250111 rs78287329 rs78287329 rs78398255 rs78398255 rs78412103 rs78412103 rs78423383 rs78423383 rs78424672 rs78424672 rs78569932 rs78569932 rs78575018 rs78575018 rs78612727 rs78612727 rs78621586 rs78621586 rs78681324 rs78681324 rs78745522 rs78745522 rs79017162 rs79017162 rs79032634 rs79032634 rs79076469 rs79076469 rs79187454 rs79187454 rs79192142 rs79192142 rs79229717 rs79229717 rs79246411 rs79246411 rs79246516 rs79246516 rs79250000 rs79250000 rs79344487 rs79344487 rs79402743 rs79402743 rs79454074 rs79454074 rs79556527 rs79556527 rs79573476 rs79573476 rs79592882 rs79592882 rs79606458 rs79606458 rs79662721 rs79662721 rs79752647 rs79752647 rs79788626 rs79788626 rs79845227 rs79845227 rs79932218 rs79932218 rs79949014 rs79967157 rs79984609 rs80011953 rs80029685 rs80054880 rs80177780 rs80177780 rs80235432 rs80235432 rs80237386 rs80237386 rs80247003 rs80247003 rs80273125 rs80273125 rs80292027 rs80292027 rs111233437 rs111233437 rs111250586 rs111250586 rs111250930 rs111250930 rs111250937 rs111250937 rs111257537 rs111257537 rs111258508 rs111258508 rs111264247 rs111264247 rs111270603 rs111270603 rs111286106 rs111286106 rs111304729 rs111304729 rs111323832 rs111323832 rs111338793 rs111338793 rs111344168 rs111344168 rs111359734 rs111359734 rs111365634 rs111365634 rs111368567 rs111368567 rs111371452 rs111371452 rs111378242 rs111378242 rs111379218 rs111379218 rs111418722 rs111418722 rs111448497 rs111448497 rs111460574 rs111460574 rs111466684 rs111466684 rs111483373 rs111483373 rs111501833 rs111501833 rs111503621 rs111503621 rs111522006 rs111522006 rs111536825 rs111536825 rs111541713 rs111541713 rs111576237 rs111576237 rs111591421 rs111591421 rs111596400 rs111596400 rs111596698 rs111596698 rs111597602 rs111597602 rs111610801 rs111610801 rs111612758 rs111612758 rs111613017 rs111613017 rs111648970 rs111648970 rs111666866 rs111666866 rs111675168 rs111675168 rs111678927 rs111678927 rs111688526 rs111688526 rs111715999 rs111715999 rs111741540 rs111741540 rs111764270 rs111764270 rs111765571 rs111765571 rs111779823 rs111779823 rs111788458 rs111788458 rs111804616 rs111804616 rs111823185 rs111823185 rs111830089 rs111830089 rs111834747 rs111834747 rs111840744 rs111840744 rs111848494 rs111848494 rs111850844 rs111850844 rs111875855 rs111875855 rs111888700 rs111888700 rs111906147 rs111906147 rs111911331 rs111911331 rs111917625 rs111917625 rs111919185 rs111919185 rs111927295 rs111927295 rs111948834 rs111948834 rs111968371 rs111968371 rs111982397 rs111982397 rs112016877 rs112016877 rs112024745 rs112024745 rs112031986 rs112031986 rs112036438 rs112036438 rs112037002 rs112037002 rs112037641 rs112037641 rs112062959 rs112062959 rs112063489 rs112063489 rs112063507 rs112063507 rs112076887 rs112076887 rs112103673 rs112127331 rs112138727 rs112140494 rs112146790 rs112155110 rs112200867 rs112207759 rs112208181 rs112209031 rs112215558 rs112216251 rs112218095 rs112234357 rs112234357 rs112269347 rs112269347 rs112289448 rs112289448 rs112292599 rs112292599 rs112323512 rs112323512 rs112326475 rs112326475 rs112377274 rs112377274 rs112392035 rs112392035 rs112395485 rs112395485 rs112401033 rs112401033 rs112401921 rs112401921 rs112402647 rs112402647 rs112438042 rs112438042 rs112438089 rs112438089 rs112441817 rs112441817 rs112475079 rs112475079 rs112475986 rs112475986 rs112476814 rs112476814 rs112477119 rs112477119 rs112487986 rs112487986 rs112507860 rs112507860 rs112528767 rs112528767 rs112538495 rs112538495 rs112560257 rs112560257 rs112587238 rs112587238 rs112587821 rs112587821 rs112594243 rs112594243 rs112615434 rs112615434 rs112621731 rs112621731 rs112641502 rs112641502 rs112651494 rs112651494 rs112661683 rs112661683 rs112668737 rs112668737 rs112696151 rs112696151 rs112716963 rs112716963 rs112742095 rs112742095 rs112747517 rs112747517 rs112749594 rs112749594 rs112761810 rs112761810 rs112771527 rs112771527 rs112784054 rs112784054 rs112835078 rs112835078 rs112839628 rs112839628 rs112846554 rs112846554 rs112850300 rs112850300 rs112851809 rs112851809 rs112853721 rs112853721 rs112854003 rs112854003 rs112858426 rs112858426 rs112861810 rs112861810 rs112865401 rs112865401 rs112870813 rs112870813 rs112872773 rs112872773 rs112875478 rs112875478 rs112906420 rs112906420 rs112916088 rs112916088 rs112918643 rs112918643 rs112921921 rs112921921 rs112931124 rs112931124 rs112935374 rs112935374 rs112940827 rs112940827 rs112944250 rs112944250 rs112953163 rs112953163 rs112964544 rs112964544 rs112967446 rs112967446 rs112968327 rs112968327 rs112969717 rs112969717 rs113015546 rs113015546 rs113023734 rs113023734 rs113044661 rs113044661 rs113045321 rs113045321 rs113064274 rs113064274 rs113066889 rs113066889 rs113069404 rs113069404 rs113091576 rs113091576 rs113115047 rs113115047 rs113115392 rs113115392 rs113121408 rs113121408 rs113125369 rs113125369 rs113126350 rs113126350 rs113151974 rs113151974 rs113169828 rs113169828 rs113170611 rs113170611 rs113179234 rs113179234 rs113183253 rs113183253 rs113188320 rs113188320 rs113202987 rs113202987 rs113205696 rs113205696 rs113230334 rs113230334 rs113242918 rs113242918 rs113251427 rs113251427 rs113256583 rs113256583 rs113268077 rs113268077 rs113282373 rs113282373 rs113310179 rs113310179 rs113313722 rs113313722 rs113321784 rs113321784 rs113339870 rs113339870 rs113343973 rs113343973 rs113363632 rs113363632 rs113386396 rs113386396 rs113387056 rs113387056 rs113395425 rs113395425 rs113397282 rs113397282 rs113399372 rs113399372 rs113405227 rs113405227 rs113410894 rs113410894 rs113436343 rs113436343 rs113440750 rs113440750 rs113453723 rs113453723 rs113454243 rs113454243 rs113461809 rs113461809 rs113462941 rs113462941 rs113464006 rs113464006 rs113473462 rs113473462 rs113473719 rs113473719 rs113486815 rs113486815 rs113487408 rs113487408 rs113487995 rs113487995 rs113496464 rs113496464 rs113523485 rs113523485 rs113524741 rs113524741 rs113528607 rs113528607 rs113532078 rs113532078 rs113555791 rs113555791 rs113556768 rs113556768 rs113564685 rs113564685 rs113571892 rs113571892 rs113620044 rs113620044 rs113635105 rs113635105 rs113647135 rs113647135 rs113647743 rs113647743 rs113668017 rs113668017 rs113668118 rs113668118 rs113670429 rs113670429 rs113698029 rs113698029 rs113701066 rs113701066 rs113712140 rs113712140 rs113712418 rs113712418 rs113725244 rs113725244 rs113726981 rs113726981 rs113736304 rs113736304 rs113739809 rs113739809 rs113758161 rs113758161 rs113762813 rs113762813 rs113765538 rs113765538 rs113773595 rs113773595 rs113786400 rs113786400 rs113793658 rs113793658 rs113805201 rs113805201 rs113810140 rs113810140 rs113817081 rs113817081 rs113823036 rs113823036 rs113843843 rs113843843 rs113852364 rs113852364 rs113854881 rs113854881 rs113856962 rs113856962 rs113878436 rs113878436 rs113924159 rs113924159 rs113929181 rs113929181 rs113934686 rs113934686 rs113934958 rs113934958 rs113962966 rs113962966 rs113965088 rs113965088 rs113970288 rs113970288 rs113972770 rs113972770 rs113974317 rs113974317 rs113974887 rs113974887 rs113986678 rs113986678 rs113992516 rs113992516 rs114011941 rs114011941 rs114015803 rs114015803 rs114034929 rs114034929 rs114041346 rs114041346 rs114066419 rs114066419 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rs562169334 rs562221655 rs562241614 rs562359765 rs562479057 rs562942295 rs563205344 rs563226460 rs563386323 rs563573207 rs563816645 rs564360620 rs564743883 rs565048403 rs565094428 rs565139465 rs565207613 rs565208099 rs565248923 rs565322678 rs565574629 rs565684347 rs565702076 rs565742498 rs565814179 rs565956329 rs566034014 rs566142173 rs566143951 rs566252979 rs566446412 rs566571960 rs566674715 rs566929862 rs567019661 rs567031244 rs567070465 rs567085288 rs567147215 rs567321063 rs567515425 rs567627031 rs567923948 rs568639194 rs568854138 rs569091578 rs569239629 rs569640441 rs569677611 rs569845377 rs569962367 rs570057212 rs570134506 rs570284595 rs570434680 rs570481252 rs570494819 rs570540391 rs570568436 rs570739482 rs571046327 rs571126634 rs571188309 rs571444284 rs571627067 rs571688267 rs571707580 rs571858448 rs572123865 rs572132946 rs572264676 rs572289083 rs572995726 rs573304417 rs573626090 rs573635286 rs573701400 rs574064711 rs574631903 rs574699574 rs574714830 rs575020384 rs575493626 rs575576508 rs576371337 rs576413572 rs576810089 rs577424330 rs577512816 rs577585887 rs577767363 rs578130804 rs578176287 rs745888965 rs745912190 rs746070999 rs746139597 rs746445670 rs746730708 rs747149849 rs747572341 rs747814035 rs748111868 rs748457600 rs748503208 rs748566644 rs748671570 rs749040318 rs749206288 rs749339734 rs749696415 rs749810038 rs750059933 rs750094828 rs750111472 rs750371301 rs750434985 rs750643875 rs750660307 rs750701461 rs751229947 rs751244419 rs751489960 rs751570209 rs751823247 rs752107900 rs752268643 rs752492015 rs752603004 rs753143398 rs753179812 rs753447999 rs753736945 rs753751784 rs753805174 rs753811762 rs754268531 rs754337458 rs754442364 rs754700910 rs755300256 rs755529677 rs755830704 rs755923622 rs756203709 rs756226189 rs756357591 rs756374014 rs756627117 rs756659975 rs756902706 rs756922265 rs756975154 rs757118435 rs757326303 rs757350519 rs757456091 rs757632435 rs757702657 rs757983305 rs758127925 rs758441088 rs758450699 rs758669037 rs758740888 rs758743151 rs758791100 rs759022945 rs759310728 rs759838149 rs759847860 rs759927823 rs760117345 rs760263735 rs760307547 rs760543626 rs760768011 rs761060484 rs761086293 rs761346248 rs761350323 rs761356209 rs761508199 rs761972512 rs762446153 rs762658317 rs762772659 rs762843856 rs763072934 rs763486566 rs763752132 rs763842121 rs763865170 rs763932321 rs763948709 rs764233928 rs764465724 rs764530548 rs764618537 rs764905399 rs765082286 rs765086588 rs765098773 rs765559116 rs765707244 rs765902788 rs765957709 rs765990289 rs766065614 rs766078306 rs766104760 rs766473336 rs766707712 rs766879687 rs767110005 rs767228203 rs767591974 rs767599971 rs767848519 rs767994963 rs768086334 rs768140735 rs768524384 rs768557514 rs768842990 rs768971571 rs769156845 rs769694874 rs769865828 rs770005111 rs770865881 rs771013822 rs771206465 rs771427937 rs771519991 rs771581042 rs771869356 rs772154187 rs772273827 rs772567394 rs772771267 rs773380744 rs773409911 rs773428210 rs773843683 rs773952098 rs774099646 rs774366349 rs774459171 rs774541765 rs774817822 rs774894415 rs774976123 rs775123800 rs775871391 rs776278042 rs776366711 rs776700600 rs776710924 rs776720378 rs776736213 rs776845219 rs776845878 rs776891477 rs777039973 rs777413325 rs778524882 rs778553230 rs778765265 rs778835669 rs778839198 rs778850959 rs778857738 rs778928957 rs779975038 rs780062911 rs780457135 rs780639476 rs780807721 rs781063480 rs781258565 rs781521687 rs781671503

HLA-DRB3基因在不同组织中的表达： [UniProt]

正向引物序列

正向引物Tm值

反向引物序列

反向引物Tm值

rank

尚未收录相关数据

HLA-DRB3基因（以及对应的蛋白质）的细胞分布位置：

[UniProt] [GenomeNet]

溶酶体
内涵体
细胞核
细胞质
液泡
细胞膜
细胞外基质
内质网
线粒体
高尔基体
细胞骨架

HLA-DRB3基因的本体（GO）信息：

GO库代码

对应的蛋白质

来源代码

GO:0002504

A0A0G2JM55(UniProtKB)

IEA

GO:0006955

A0A0G2JM55(UniProtKB)

IEA

GO:0016021

A0A0G2JM55(UniProtKB)

IEA

GO:0042613

A0A0G2JM55(UniProtKB)

IEA

GO:0002504

A0A0G2JMR0(UniProtKB)

IEA

GO:0006955

A0A0G2JMR0(UniProtKB)

IEA

GO:0016021

A0A0G2JMR0(UniProtKB)

IEA

GO:0042613

A0A0G2JMR0(UniProtKB)

IEA

GO:0002504

A0A0G2JMW2(UniProtKB)

IEA

GO:0006955

A0A0G2JMW2(UniProtKB)

IEA

GO:0016021

A0A0G2JMW2(UniProtKB)

IEA

GO:0042613

A0A0G2JMW2(UniProtKB)

IEA

GO:0002504

A0A0G2JNS5(UniProtKB)

IEA

GO:0006955

A0A0G2JNS5(UniProtKB)

IEA

GO:0016021

A0A0G2JNS5(UniProtKB)

IEA

GO:0042613

A0A0G2JNS5(UniProtKB)

IEA

GO:0002504

A0A0G2JP73(UniProtKB)

IEA

GO:0006955

A0A0G2JP73(UniProtKB)

IEA

GO:0016021

A0A0G2JP73(UniProtKB)

IEA

GO:0042613

A0A0G2JP73(UniProtKB)

IEA

GO:0000139

P79483(UniProtKB)

TAS

GO:0000139

P79483(UniProtKB)

TAS

GO:0005765

P79483(UniProtKB)

IDA

GO:0005765

P79483(UniProtKB)

TAS

GO:0005765

P79483(UniProtKB)

TAS

GO:0005765

P79483(UniProtKB)

TAS

GO:0005765

P79483(UniProtKB)

TAS

GO:0005765

P79483(UniProtKB)

TAS

GO:0005765

P79483(UniProtKB)

TAS

GO:0005765

P79483(UniProtKB)

TAS

GO:0005765

P79483(UniProtKB)

TAS

GO:0005886

P79483(UniProtKB)

TAS

GO:0005886

P79483(UniProtKB)

TAS

GO:0005886

P79483(UniProtKB)

TAS

GO:0005886

P79483(UniProtKB)

TAS

GO:0005886

P79483(UniProtKB)

TAS

GO:0005886

P79483(UniProtKB)

TAS

GO:0005886

P79483(UniProtKB)

TAS

GO:0005886

P79483(UniProtKB)

TAS

GO:0005886

P79483(UniProtKB)

TAS

GO:0005886

P79483(UniProtKB)

TAS

GO:0005886

P79483(UniProtKB)

TAS

GO:0005886

P79483(UniProtKB)

TAS

GO:0005886

P79483(UniProtKB)

TAS

GO:0005886

P79483(UniProtKB)

TAS

GO:0005886

P79483(UniProtKB)

TAS

GO:0005886

P79483(UniProtKB)

TAS

GO:0005886

P79483(UniProtKB)

TAS

GO:0005887

P79483(UniProtKB)

NAS

GO:0007165

P79483(UniProtKB)

NAS

GO:0012507

P79483(UniProtKB)

TAS

GO:0012507

P79483(UniProtKB)

TAS

GO:0016020

P79483(UniProtKB)

IDA

GO:0019886

P79483(UniProtKB)

TAS

GO:0030658

P79483(UniProtKB)

TAS

GO:0030658

P79483(UniProtKB)

TAS

GO:0030666

P79483(UniProtKB)

TAS

GO:0030666

P79483(UniProtKB)

TAS

GO:0030669

P79483(UniProtKB)

TAS

GO:0030669

P79483(UniProtKB)

TAS

GO:0031295

P79483(UniProtKB)

TAS

GO:0031902

P79483(UniProtKB)

IDA

GO:0032395

P79483(UniProtKB)

NAS

GO:0032588

P79483(UniProtKB)

TAS

GO:0032588

P79483(UniProtKB)

TAS

GO:0032588

P79483(UniProtKB)

TAS

GO:0032588

P79483(UniProtKB)

TAS

GO:0032588

P79483(UniProtKB)

TAS

GO:0042605

P79483(UniProtKB)

ISS

GO:0042613

P79483(UniProtKB)

ISS

GO:0050852

P79483(UniProtKB)

TAS

GO:0060333

P79483(UniProtKB)

TAS

GO:0071556

P79483(UniProtKB)

TAS

GO:0071556

P79483(UniProtKB)

TAS

GO:0071556

P79483(UniProtKB)

TAS

GO:0071556

P79483(UniProtKB)

TAS

序号	作用方式	资源库来源/分值	基因名称	基因名称

可能调控HLA-DRB3基因的相关microRNA：

通路基因列表

疾病名称

关系值

NofPmids

NofSnps

来源

疾病名称	关系值	NofPmids	NofSnps	来源
Lupus Erythematosus, Systemic	0.014202192	6	0	GAD
Sarcoidosis	0.008186863	7	0	BeFree_GAD
Hepatitis, Autoimmune	0.005362824	3	0	BeFree_GAD_LHGDN
Autoimmune Diseases	0.005091382	2	0	GAD_LHGDN
Abortion, Habitual	0.004734064	2	0	GAD
Hepatitis C	0.004734064	2	0	GAD
HIV Infections	0.004734064	2	0	GAD
Psoriasis	0.004734064	2	0	GAD
Tuberculosis	0.004734064	2	0	GAD
Aortic Aneurysm, Abdominal	0.004734064	2	0	GAD
Latex allergy	0.004734064	2	0	GAD
Celiac Disease	0.002995792	2	0	BeFree_LHGDN
Ulcerative Colitis	0.002995792	2	0	BeFree_LHGDN
Arthritis	0.00272435	1	0	LHGDN
Inclusion Body Myositis (disorder)	0.00272435	1	0	LHGDN
Diabetes Mellitus, Insulin-Dependent	0.002638474	2	0	BeFree_GAD
Abruptio Placentae	0.002367032	1	0	GAD
Brain Neoplasms	0.002367032	1	0	GAD
Churg-Strauss Syndrome	0.002367032	1	0	GAD
Glioma	0.002367032	1	0	GAD
Hallucinations	0.002367032	1	0	GAD
Inflammation	0.002367032	1	0	GAD
Myeloid Leukemia, Chronic	0.002367032	1	0	GAD
Liver Cirrhosis	0.002367032	1	0	GAD
Multiple Sclerosis	0.002367032	1	0	GAD
Narcolepsy	0.002367032	1	0	GAD
Bullous pemphigoid	0.002367032	1	0	GAD
Periodontitis	0.002367032	1	0	GAD
Pityriasis Rosea	0.002367032	1	0	GAD
Pregnancy Complications	0.002367032	1	0	GAD
Rheumatic Heart Disease	0.002367032	1	0	GAD
Rhinitis	0.002367032	1	0	GAD
Kaposi Sarcoma	0.002367032	1	0	GAD
Systemic Scleroderma	0.002367032	1	0	GAD
Thrombocytopenia	0.002367032	1	0	GAD
Gestational Diabetes	0.002367032	1	0	GAD
Dementia	0.002367032	1	0	GAD
Pregnancy loss	0.002367032	1	0	GAD
Lewy Body Disease	0.002367032	1	0	GAD
Thrombotic thrombocytopenic purpura, acquired	0.002367032	1	0	GAD
Graves Disease	0.001357209	5	0	BeFree
Crohn Disease	0.000542884	2	0	BeFree
Rheumatoid Arthritis	0.000271442	1	0	BeFree
Obesity	0.000271442	1	0	BeFree
Purpura, Thrombotic Thrombocytopenic	0.000271442	1	0	BeFree
Essential Hypertension	0.000271442	1	0	BeFree
Chronic Periodontitis	0.000271442	1	0	BeFree
Aspirin-sensitive asthma with nasal polyps	0.000271442	1	0	BeFree
Immune thrombocytopenic purpura	0.000271442	1	0	BeFree
Inclusion Body Myopathy, Sporadic	0.000271442	1	0	BeFree
Juvenile arthritis	0.000271442	1	0	BeFree
Juvenile rheumatoid arthritis	0.000271442	1	0	BeFree