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Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H2A family. [provided by RefSeq, Jul 2008]
[中文简述(自动翻译):]  组蛋白是负责在真核生物染色体纤维的核小体结构基本核蛋白质。每四个核心组蛋白中的两个分子(H2A,H2B,H3和H4)形成八聚体,其周围约146的DNA的碱基被包裹在重复单元,称为核小体。接头组蛋白,H1与染色质成高阶结构的压实核小体和功能之间的接头DNA相互作用。这种基因是无内含子并且编码所述组蛋白H2A家族的一个成员。 [由RefSeq的,2008年7月提供]
HIST2H2AC基因(以及对应的蛋白质)的细胞分布位置:
HIST2H2AC基因的本体(GO)信息:
| 疾病名称 | 关系值 | NofPmids | NofSnps | 来源 |
| Glioma | 0.000271442 | 1 | 0 | BeFree |
| Chronic Lymphocytic Leukemia | 0.000271442 | 1 | 0 | BeFree |
| Thyroiditis | 0.000271442 | 1 | 0 | BeFree |
| Arthritis, Collagen-Induced | 0.000271442 | 1 | 0 | BeFree |
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