HIST1H4H基因详情-基因数据库-基因云馆

HIST1H4H(histone cluster 1, H4h) 转至新版数据库

基因简称(symbol)

HIST1H4H [HGNC] [GeneCards] [NCBI]

基因种类(locus group)

protein-coding gene

同源简称(alias symbol)

H4/h

基因家族代码(gene_family_id)

864 [HGNC] [GenScript]

omim代码

602828

entrez码

8365 [Vega]

vega基因码

OTTHUMG00000014454

ensembl基因码

ENSG00000158406 [Ensembl]

基因家族(gene family)

Histones

refseq数据库代号

NM_003543

更多...

基因种类(locus_type)

gene with protein product

基因名称状态(status)

Approved

location_sortable

06p22.1

同源基因名称(alias name)

基因名称批准使用时间(date_approved_reserved)

1998-09-07T00:00:00Z

基因简称更名时间(date_symbol_changed)

2003-02-14T00:00:00Z

基因名称更名时间(date_name_changed)

2006-10-11T00:00:00Z

更新时间(date_modified)

2014-11-19T00:00:00Z

ucsc码

uc003nhm.2

ena

X60487

ccds数据码

CCDS4604

uniprot数据码

P62805

pubmed代码

9119399|12408966

mgd码

MGI:2448439

rgd码

生命科学数据库(lsdb)

更新时间(date modified)

2014-11-19T00:00:00Z

cosmic

HIST1H4H

mirbase

基因曾用简称(prev symbol)

H4FH

基因曾用名称(prev name)

H4 histone family, member H|histone 1, H4h

homeodb

cosmic

HIST1H4H

snornabase

bioparadigms slc

orphanet

假基因信息(pseudogeneorg)

horde id

merops

imgt

iuphar

kznf基因类别

mamit-trnadb

cd

LncRNA数据库

酶代码

中间纤维数据库

收起

6p22.1

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H4 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6. [provided by RefSeq, Jul 2008]

[中文简述(自动翻译):] 组蛋白是负责在真核生物染色体纤维的核小体结构基本核蛋白质。每四个核心组蛋白中的两个分子（H2A，H2B，H3和H4）形成八聚体，其周围约146的DNA的碱基被包裹在重复单元，称为核小体。接头组蛋白，H1与染色质成高阶结构的压实核小体和功能之间的接头DNA相互作用。这种基因是无内含子并且编码所述组蛋白H4家族的一个成员。从这个基因转录缺乏聚腺苷酸尾，而是包含回文终端元件。该基因大组蛋白基因簇中发现[由RefSeq的，2008年7月提供] 6号染色体

OMIM数据库中对HIST1H4H基因的介绍 Wikipedia数据库中对HIST1H4H基因的介绍

HIST1H4H基因的碱基序列：[NCBI]

HIST1H4H基因的碱基突变：显示全部snp

rs1124999 rs1125000 rs2393592 rs2393593 rs3999544 rs6905505 rs9358918 rs11548889 rs12194634 rs16891517 rs16891518 rs34916901 rs41266829 rs41266831 rs56763414 rs57740622 rs58812262 rs59484333 rs59998274 rs61746492 rs62396221 rs73395332 rs73395344 rs73395352 rs74581959 rs74756478 rs75136657 rs75184984 rs75337077 rs75747360 rs75835444 rs75886242 rs75894867 rs77357982 rs77540645 rs77862550 rs77906847

rs78722424 rs79022126 rs79089106 rs79305939 rs79361068 rs80236651 rs80246231 rs111249032 rs114154738 rs139344925 rs140008751 rs140286420 rs140553626 rs140795260 rs140969901 rs141511420 rs141555505 rs143923288 rs144152120 rs144666631 rs144759258 rs145256515 rs145272223 rs146702488 rs147282032 rs148484071 rs148651672 rs150879518 rs181114978 rs181964931 rs182806313 rs182848845 rs183447680 rs184358916 rs184509093 rs184769281 rs184973741 rs185427308 rs185795689 rs186607862 rs187423550 rs188281189 rs188983313 rs188990278 rs189303294 rs190977255 rs191354075 rs192165655 rs192347806 rs192725287 rs192795602 rs199872319 rs199970263 rs199971745 rs200373070 rs200409942 rs200515414 rs201139253 rs201165242 rs201648460 rs201746650 rs201782924 rs202061275 rs202065311 rs202066850 rs367638032 rs367980184 rs368162052 rs368693802 rs368960334 rs369590627 rs370115734 rs370283565 rs370406254 rs370659878 rs370765937 rs370943039 rs371467553 rs371683978 rs373009713 rs373098952 rs373641150 rs374008607 rs375187634 rs375857260 rs376365027 rs376549490 rs376550213 rs377418572 rs377545151 rs377587344 rs397731666 rs527297423 rs528956995 rs529476157 rs529624822 rs530039376 rs530585526 rs530745950 rs531336659 rs532161604 rs532366723 rs532499742 rs532893631 rs534527760 rs534937692 rs534954485 rs535033468 rs535830260 rs536047158 rs536670700 rs536787792 rs537580546 rs537767940 rs538346920 rs540905876 rs541803313 rs542292125 rs542752467 rs544041817 rs544936711 rs545583063 rs545756132 rs545893716 rs546646565 rs547074491 rs547946169 rs547986347 rs548260994 rs552239314 rs552433796 rs553032284 rs553118352 rs553995824 rs554894379 rs555388599 rs555873864 rs556946611 rs556970184 rs558209314 rs558295057 rs558683531 rs559935005 rs560447915 rs560471333 rs560966360 rs561375423 rs561376348 rs561971125 rs562704212 rs563019138 rs563257632 rs563833210 rs563858532 rs566324371 rs566458812 rs567411321 rs567432327 rs567497288 rs567778730 rs568561213 rs571153862 rs573582499 rs574964275 rs575741367 rs576173957 rs576833183 rs577091416 rs577213799 rs577484049 rs745373898 rs745538544 rs745889337 rs746821323 rs746933092 rs746940582 rs747187372 rs747301666 rs747548213 rs747605319 rs747920058 rs748128721 rs748287698 rs748350611 rs748452774 rs748810952 rs748918877 rs749546545 rs749824324 rs749871301 rs750395074 rs750673210 rs750724582 rs751108867 rs751153933 rs751302752 rs751356332 rs751532587 rs752058100 rs752107532 rs752444196 rs752562815 rs752731488 rs753248956 rs753793760 rs753812930 rs754076309 rs754692167 rs754869330 rs754914076 rs755224217 rs755522692 rs755706161 rs755955796 rs756014793 rs756059976 rs756243326 rs756260928 rs756828273 rs757502118 rs757570489 rs757632569 rs758278415 rs758850799 rs759155398 rs759999877 rs760101022 rs760444800 rs760955887 rs761188495 rs761737525 rs761771008 rs762514674 rs762559798 rs762975969 rs763143858 rs763741872 rs764523469 rs765268384 rs765321499 rs765741624 rs765851662 rs765897084 rs766191416 rs766453964 rs766818614 rs766917771 rs767048642 rs767127586 rs767255330 rs767804770 rs768333448 rs769287159 rs769560829 rs769932118 rs770679124 rs770859181 rs771131997 rs771187095 rs771495436 rs771694052 rs772290046 rs772965193 rs773103052 rs773179450 rs773868358 rs774473271 rs775557463 rs775870820 rs776131682 rs777146579 rs777638336 rs778137756 rs778648363 rs779261934 rs779339553 rs779642956 rs779832467 rs779977183 rs780157186 rs780214864 rs780851749 rs781430067 rs781602027 rs796080009

HIST1H4H基因在不同组织中的表达： [UniProt]

正向引物序列

正向引物Tm值

反向引物序列

反向引物Tm值

rank

GGTGTCAAGCGAATTTCTGG

60

GGAACACCTTCAGAACACC

58

CGCTGTCACTTACACAGAG

58

GTAGACCACATCCATTGCTG

59

GTGTCAAGCGAATTTCTGG

57

AGGAACACCTTCAGAACAC

57

尚未收录相关数据

HIST1H4H基因（以及对应的蛋白质）的细胞分布位置：

[UniProt] [GenomeNet]

溶酶体
内涵体
细胞核
细胞质
液泡
细胞膜
细胞外基质
内质网
线粒体
高尔基体
细胞骨架

HIST1H4H基因的本体（GO）信息：

序号	作用方式	资源库来源/分值	基因名称	基因名称

可能调控HIST1H4H基因的相关microRNA：

hsa-miR-34a hsa-miR-9 hsa-miR-98 hsa-miR-125b

通路基因列表

疾病名称

关系值

NofPmids

NofSnps

来源

疾病名称	关系值	NofPmids	NofSnps	来源
Prostatic Neoplasms	0.12	1	0	CTD_human
Carcinogenesis	0.001085767	4	0	BeFree
Myeloid Leukemia, Chronic	0.000814326	3	0	BeFree
Liver carcinoma	0.000814326	3	0	BeFree
Lupus Erythematosus, Systemic	0.000542884	2	0	BeFree
Mammary Neoplasms	0.000542884	2	0	BeFree
Non-Small Cell Lung Carcinoma	0.000271442	1	0	BeFree
Squamous cell carcinoma	0.000271442	1	0	BeFree
Congenital chromosomal disease	0.000271442	1	0	BeFree
Glioma	0.000271442	1	0	BeFree
Leukemia, Myelocytic, Acute	0.000271442	1	0	BeFree
melanoma	0.000271442	1	0	BeFree
Neoplasm Metastasis	0.000271442	1	0	BeFree
Rett Syndrome	0.000271442	1	0	BeFree
Systemic Scleroderma	0.000271442	1	0	BeFree
Small cell carcinoma of lung	0.000271442	1	0	BeFree
Embryonal Carcinoma	0.000271442	1	0	BeFree
Muscular Dystrophy, Facioscapulohumeral	0.000271442	1	0	BeFree
Malignant neoplasm of colon stage IV	0.000271442	1	0	BeFree
Non-small cell lung cancer stage I	0.000271442	1	0	BeFree
Squamous cell carcinoma of esophagus	0.000271442	1	0	BeFree
Multiple malignancy	0.000271442	1	0	BeFree
Colorectal Cancer	0.000271442	1	0	BeFree