HIST1H2BN(histone cluster 1, H2bn) 转至新版数据库

基因基本信息

基因基本信息

基因简称(symbol)
    [HGNC]     [GeneCards]     [NCBI]
基因种类(locus group)
同源简称(alias symbol)
基因家族代码(gene_family_id)
    [HGNC]     [GenScript]
omim代码
entrez码
    [Vega]
vega基因码
ensembl基因码
    [Ensembl]
基因家族(gene family)
refseq数据库代号

更多...

基因种类(locus_type)
基因名称状态(status)
location_sortable
同源基因名称(alias name)
基因名称批准使用时间(date_approved_reserved)
基因简称更名时间(date_symbol_changed)
基因名称更名时间(date_name_changed)
更新时间(date_modified)
ucsc码
ena
ccds数据码
uniprot数据码
pubmed代码
mgd码
rgd码
生命科学数据库(lsdb)
更新时间(date modified)
cosmic
mirbase
基因曾用简称(prev symbol)
基因曾用名称(prev name)
homeodb
cosmic
snornabase
bioparadigms slc
orphanet
假基因信息(pseudogeneorg)
horde id
merops
imgt
iuphar
kznf基因类别
mamit-trnadb
cd
LncRNA数据库
酶代码
中间纤维数据库

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基因染色体位置

基因染色体位置

6p22.1
基因染色体位置图

基因简述

基因简述

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H2B family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the small histone gene cluster on chromosome 6p22-p21.3. [provided by RefSeq, Jul 2008]

[中文简述(自动翻译):]  组蛋白是负责在真核生物染色体纤维的核小体结构基本核蛋白质。每四个核心组蛋白中的两个分子（H2A，H2B，H3和H4）形成八聚体，其周围约146的DNA的碱基被包裹在重复单元，称为核小体。接头组蛋白，H1与染色质成高阶结构的压实核小体和功能之间的接头DNA相互作用。这种基因是无内含子并且编码所述组蛋白H2B家族的一个成员。从这个基因转录缺乏聚腺苷酸尾，而是包含回文终端元件。该基因在染色体6p22-p21.3小组蛋白基因簇中发现。 [由RefSeq的，2008年7月提供]

OMIM数据库中对HIST1H2BN基因的介绍     Wikipedia数据库中对HIST1H2BN基因的介绍

基因序列

基因序列

HIST1H2BN基因的碱基序列：[NCBI]

基因突变

基因突变

HIST1H2BN基因的碱基突变：           显示全部snp
rs201003       rs9468236       rs13212651       rs34706883       rs57475376       rs72847349       rs80212940       rs111967279       rs112586220       rs138689538       rs139301244       rs139346689       rs141058151       rs141332149       rs141561459       rs141744243       rs141833276       rs142071687       rs142211266       rs142383851       rs143070428       rs143955895       rs144042626       rs144837583       rs144906486       rs146210589       rs146250974       rs146995288       rs148624950       rs149036829       rs149360074       rs149494377       rs150181243       rs150225021       rs150909234       rs151133448       rs180837058      
rs181670715       rs183129904       rs184872496       rs186234493       rs187076355       rs188027160       rs191039835       rs191671960       rs199543763       rs200020824       rs200382620       rs200699943       rs201101947       rs201769545       rs202190527       rs367544020       rs368057561       rs368231070       rs368300063       rs368785047       rs368822660       rs368921870       rs369660098       rs370331104       rs370602738       rs370729564       rs370975960       rs371861857       rs372307711       rs372717134       rs373121961       rs373592416       rs374107828       rs374286283       rs374620650       rs375127285       rs375163457       rs375174097       rs375292839       rs375453686       rs376142763       rs376295234       rs377613254       rs377742867       rs528586578       rs529311158       rs530368544       rs530431001       rs532179629       rs536345739       rs537051972       rs537361695       rs537962329       rs540089352       rs542696635       rs544181666       rs544443198       rs544484889       rs544693420       rs545193810       rs549257446       rs551039045       rs551526680       rs552227550       rs553693871       rs554602359       rs556877226       rs557050718       rs558278851       rs558800262       rs559449457       rs560181028       rs561319945       rs563696005       rs565273631       rs565925645       rs566536502       rs568832662       rs569017389       rs571150777       rs573049870       rs575606709       rs575711628       rs745850903       rs745961889       rs746057696       rs746231334       rs746609092       rs746739154       rs746824735       rs746829199       rs747587408       rs747875088       rs748042771       rs748061432       rs748101619       rs748252336       rs748442720       rs748458243       rs748695710       rs748698306       rs748769774       rs749223493       rs749235171       rs749288311       rs749401392       rs749454776       rs749779972       rs749853515       rs750141564       rs750261282       rs750432899       rs750509779       rs750636387       rs751088866       rs751283665       rs751407212       rs752232308       rs752237692       rs752719689       rs752799977       rs753178718       rs753198609       rs753390974       rs753411630       rs753465036       rs753492843       rs753609565       rs753942506       rs754126602       rs754307126       rs754364671       rs754407522       rs754457492       rs754461130       rs754537467       rs754655905       rs754722037       rs754728183       rs755314387       rs755440823       rs755635299       rs755732231       rs755759469       rs755949889       rs756603959       rs756809810       rs756876974       rs757411215       rs757567561       rs758328732       rs758402698       rs758508306       rs758513815       rs758699136       rs758718283       rs758747459       rs759229774       rs759460168       rs759481719       rs759535364       rs759755555       rs759789376       rs760717593       rs760789692       rs760967268       rs761136744       rs761177951       rs761357869       rs761545843       rs761731799       rs762034527       rs762122622       rs762295387       rs762490700       rs762657486       rs762741533       rs762757051       rs762856742       rs763318158       rs763444350       rs763499539       rs763508699       rs763734651       rs764480802       rs764698025       rs764904188       rs764966750       rs765052099       rs765176704       rs765564594       rs765687790       rs765801319       rs766088467       rs766204134       rs766327047       rs766426531       rs766510578       rs767277017       rs767657350       rs767691153       rs767746288       rs767838026       rs768172784       rs768401983       rs768438249       rs768441957       rs768453272       rs768501837       rs768616181       rs768793613       rs769222848       rs769278527       rs769541447       rs769827696       rs770215833       rs770291273       rs770363942       rs770490227       rs770490807       rs770987466       rs771166168       rs771316947       rs771390643       rs771603078       rs771829335       rs771928752       rs772051433       rs772108612       rs772275160       rs772446900       rs773528950       rs773984988       rs774104828       rs774256487       rs774412686       rs774493195       rs774654470       rs774754469       rs774976261       rs775122572       rs775338049       rs775416456       rs775449129       rs775905178       rs776031962       rs776117789       rs776566851       rs776728807       rs776745918       rs776924559       rs777101543       rs777708966       rs777764146       rs777764253       rs777892657       rs778094509       rs778353065       rs778946406       rs778999806       rs779014502       rs779327004       rs779378155       rs779586687       rs780561476       rs780736877       rs780824411       rs781034322       rs781502104       rs781744556       rs781765469       rs201004       rs71546575       rs73386609       rs141844723       rs143710027       rs148098467       rs184756916       rs187908633       rs191487041       rs192148588       rs529339950       rs530734681       rs550111577       rs552090529       rs559545847       rs563541373       rs565934751      

基因表达

基因表达

HIST1H2BN基因在不同组织中的表达：    [UniProt]

基因在不同组织中的表达图

基因引物

基因引物

正向引物序列
正向引物Tm值
反向引物序列
反向引物Tm值
rank
ATTACAACAAGCGCTCGAC
59
GGAGACATTATTTGGAACTGGT
59
GTACACCAGTTCCAAGAAGAG
58
GCCAAATCTTGAGCTTTCTG
58
ACACCAGTTCCAAGAAGAG
57
GCCAAATCTTGAGCTTTCTG
58
TTCGTCAATGACATCTTCGAG
59
CTTGTTGTAATGCGCCAGG
60
GTACACCAGTTCCAAGAAGAG
58
AGCCAAATCTTGAGCTTTCTG
59
CAATGACATCTTCGAGCGC
60
TTTCTCTTCCGAACGTTCC
58
ATTACAACAAGCGCTCGAC
59
TGGAGACATTATTTGGAACTGG
59
ATTACAACAAGCGCTCGAC
59
TTTCTCTTCCGAACGTTCC
58
CATTACAACAAGCGCTCGA
59
TTTCTCTTCCGAACGTTCC
58
AAAGGCCCAGAAGAAGGAC
60
TACACGGAGTAGCTCTCCT
59

转录因子

转录因子

      尚未收录相关数据

基因本体信息

HIST1H2BN基因（以及对应的蛋白质）的细胞分布位置：

[UniProt]     [GenomeNet]

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • 溶酶体
  • 内涵体
  • 细胞核
  • 细胞质
  • 液泡
  • 细胞膜
  • 细胞外基质
  • 内质网
  • 线粒体
  • 高尔基体
  • 细胞骨架

HIST1H2BN基因的本体（GO）信息：

GO库代码
对应的蛋白质
来源代码
GO:0000786
Q99877(UniProtKB)
NAS
GO:0000788
Q99877(UniProtKB)
IBA
GO:0003677
Q99877(UniProtKB)
IBA
GO:0003677
Q99877(UniProtKB)
NAS
GO:0005634
Q99877(UniProtKB)
IDA
GO:0005634
Q99877(UniProtKB)
IDA
GO:0005654
Q99877(UniProtKB)
IDA
GO:0005654
Q99877(UniProtKB)
TAS
GO:0005737
Q99877(UniProtKB)
IDA
GO:0006334
Q99877(UniProtKB)
IBA
GO:0006334
Q99877(UniProtKB)
NAS
GO:0046982
Q99877(UniProtKB)
IEA
GO:0070062
Q99877(UniProtKB)
IDA
GO:0070062
Q99877(UniProtKB)
IDA
GO:0000786
U3KQK0(UniProtKB)
IEA
GO:0003677
U3KQK0(UniProtKB)
IEA
GO:0005654
U3KQK0(UniProtKB)
IDA
GO:0005737
U3KQK0(UniProtKB)
IDA
GO:0046982
U3KQK0(UniProtKB)
IEA

基因相互作用关系

基因相互作用关系

基因与其他基因之间的相互作用关系图
序号 作用方式 资源库来源/分值 基因名称 基因名称

基因相关microRNA

基因相关microRNA

可能调控HIST1H2BN基因的相关microRNA：     

基因通路图

基因通路图

基因的通路属性图
通路基因列表

基因相关疾病

基因相关疾病

疾病名称 关系值 NofPmids NofSnps 来源
疾病名称 关系值 NofPmids NofSnps 来源
Lupus Erythematosus, Systemic 0.004734064 1 2 GAD
Ovarian Carcinoma 0.000271442 1 0 BeFree
Malignant neoplasm of ovary 0.000271442 1 0 BeFree

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