HHEX(hematopoietically expressed homeobox)

基因基本信息

基因基本信息

基因简称(symbol)
    [HGNC]     [GeneCards]     [NCBI]
基因种类(locus group)
同源简称(alias symbol)
基因家族代码(gene_family_id)
    [HGNC]     [GenScript]
omim代码
entrez码
    [Vega]
vega基因码
ensembl基因码
    [Ensembl]
基因家族(gene family)
refseq数据库代号

更多...

基因种类(locus_type)
基因名称状态(status)
location_sortable
同源基因名称(alias name)
基因名称批准使用时间(date_approved_reserved)
基因简称更名时间(date_symbol_changed)
基因名称更名时间(date_name_changed)
更新时间(date_modified)
ucsc码
ena
ccds数据码
uniprot数据码
pubmed代码
mgd码
rgd码
生命科学数据库(lsdb)
更新时间(date modified)
cosmic
mirbase
基因曾用简称(prev symbol)
基因曾用名称(prev name)
homeodb
cosmic
snornabase
bioparadigms slc
orphanet
假基因信息(pseudogeneorg)
horde id
merops
imgt
iuphar
kznf基因类别
mamit-trnadb
cd
LncRNA数据库
酶代码
中间纤维数据库

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基因染色体位置

基因染色体位置

10q23.33
基因染色体位置图

基因简述

基因简述

This gene encodes a member of the homeobox family of transcription factors, many of which are involved in developmental processes. Expression in specific hematopoietic lineages suggests that this protein may play a role in hematopoietic differentiation. [provided by RefSeq, Jul 2008]

[中文简述(自动翻译):]  该基因编码的同源框转录因子家族，其中许多都涉及发育过程中的一员。在特定造血谱系表达表明该蛋白可能在造血细胞分化的作用。 [由RefSeq的，2008年7月提供]

OMIM数据库中对HHEX基因的介绍     Wikipedia数据库中对HHEX基因的介绍

基因序列

基因序列

HHEX基因的碱基序列：[NCBI]

基因突变

基因突变

HHEX基因的碱基突变：           显示全部snp
rs949579       rs1418387       rs2229328       rs2275729       rs2275730       rs9420589       rs11187135       rs11319879       rs12781513       rs34266926       rs34372348       rs41290176       rs71480833       rs74149106       rs74149107       rs74149108       rs75065123       rs75128714       rs76425330       rs76501574       rs80106076       rs111794686       rs111896676       rs111994905       rs112686755       rs112926556       rs113121942       rs113415627       rs113555157       rs114001966       rs114344374       rs114403381       rs115065080       rs115067264       rs117639730       rs117662920       rs117739875      
rs138736109       rs138744798       rs139182180       rs140982034       rs141036674       rs141852233       rs142036619       rs143701387       rs143940637       rs143956301       rs144794262       rs145584202       rs146499847       rs147300243       rs147778208       rs148939627       rs149466636       rs149759733       rs149951495       rs150387891       rs150545931       rs150804177       rs181066526       rs181897153       rs182124968       rs183418738       rs183472460       rs184238109       rs184882393       rs185220612       rs185484899       rs186282501       rs186807208       rs187139114       rs188232439       rs188685589       rs189936100       rs189988036       rs190359554       rs190847445       rs191529741       rs191640546       rs191684511       rs192425038       rs192864353       rs193299586       rs199544448       rs199770552       rs200052261       rs200072506       rs200607821       rs200962922       rs201671743       rs201876873       rs370419063       rs370777153       rs370840411       rs371003144       rs372189760       rs372629981       rs372666577       rs372911659       rs373773105       rs374722314       rs375633003       rs375811692       rs376915003       rs527969107       rs528032641       rs528370402       rs528436031       rs528438935       rs528846382       rs528957996       rs530700567       rs530907777       rs531182483       rs532314945       rs532464203       rs532842622       rs532873184       rs533335614       rs533824584       rs534293827       rs534348187       rs534358169       rs534704292       rs534777764       rs534832956       rs535737516       rs535776260       rs536093981       rs536345082       rs536544998       rs536758535       rs536760157       rs537086438       rs537144231       rs538151851       rs538680375       rs539013549       rs540063785       rs540359292       rs540657123       rs540724252       rs541941009       rs542053391       rs542070126       rs544051937       rs544169564       rs544399912       rs544628160       rs544652387       rs545911859       rs546016898       rs546076206       rs546230628       rs546241322       rs548058634       rs548134764       rs548391548       rs548684677       rs549978858       rs550978415       rs552119810       rs552192088       rs552204292       rs552512817       rs553602398       rs553756934       rs554220013       rs554275552       rs554282980       rs554546196       rs554678432       rs555690607       rs555953607       rs555996923       rs556264097       rs556304471       rs556519637       rs556825348       rs556891405       rs557199640       rs557491363       rs557499469       rs557595980       rs558044709       rs558170145       rs558196263       rs558427078       rs558595613       rs558650707       rs558828665       rs559457685       rs559715342       rs559910819       rs560488859       rs561307515       rs561738313       rs561983167       rs562305227       rs563540100       rs563603594       rs563896030       rs563942416       rs564324947       rs565614125       rs565692959       rs565836585       rs565840520       rs566090388       rs566151380       rs567472459       rs567749173       rs567776972       rs567976148       rs568239897       rs569073176       rs569888957       rs570047324       rs570079121       rs570499391       rs571252950       rs571893737       rs572155443       rs573117244       rs573298431       rs574038551       rs574100012       rs574392865       rs574754629       rs575069468       rs575542303       rs575746087       rs576251843       rs576311769       rs576535903       rs577387633       rs577498410       rs577511549       rs578130983       rs745348021       rs745436355       rs745904454       rs746055782       rs746224197       rs746590738       rs746727301       rs746868626       rs747061001       rs747172564       rs747713800       rs748494650       rs749189919       rs749396288       rs749658938       rs750022059       rs750063118       rs750323865       rs750405872       rs750572886       rs750824236       rs751190903       rs751457715       rs751698879       rs751797640       rs751809074       rs752175687       rs752804342       rs752995067       rs753394415       rs753656580       rs753742389       rs754044224       rs754315134       rs754334398       rs754419200       rs755049912       rs755244382       rs755802806       rs755816063       rs755960214       rs757112503       rs757308946       rs757653686       rs758306656       rs758719291       rs759225685       rs759513364       rs760441003       rs760793981       rs761135488       rs761230882       rs761709985       rs761758165       rs762070983       rs762086181       rs762671425       rs762793686       rs763193949       rs763407436       rs764354010       rs764391242       rs764505609       rs764744029       rs765075792       rs765458169       rs765524106       rs765838543       rs766112006       rs766149896       rs766233439       rs766838272       rs766975075       rs767044329       rs767424725       rs767447009       rs767789592       rs768240433       rs768369825       rs768637992       rs769590079       rs769831392       rs770197482       rs770221901       rs770553856       rs770598208       rs770977782       rs771228365       rs771425069       rs771498064       rs771793065       rs771813965       rs772515492       rs772927960       rs773023789       rs773419319       rs773604024       rs774170320       rs774776384       rs775302104       rs775484791       rs775878598       rs776058599       rs776443220       rs776542212       rs776889398       rs777011688       rs777102021       rs777393392       rs777407704       rs777471219       rs777779960       rs778415006       rs778979179       rs779009264       rs779264732       rs779268157       rs779389753       rs779766063       rs780241760       rs780255912       rs780435092       rs780820204       rs780836792       rs781261088      

基因表达

基因表达

HHEX基因在不同组织中的表达：    [UniProt]

基因在不同组织中的表达图

基因引物

基因引物

正向引物序列
正向引物Tm值
反向引物序列
反向引物Tm值
rank
TACATCGAGGACATCCTGG
58
ATCATCAAACCCTCGAGGC
60
CTGGAGAAGAAATTCGAGACG
59
TGCTTTGAGGGTTCTCCTG
60
CCAACTCCTCCTTCACCAG
60
GCATCATCAAACCCTCGAG
59
AACCTGGTTTCAGAATCGAC
58
TGCTTTGAGGGTTCTCCTG
60
AAACCTGGTTTCAGAATCGAC
59
TGCTTTGAGGGTTCTCCTG
60
AACCTGGTTTCAGAATCGAC
58
TGCTTTGAGGGTTCTCCTG
60
GAGAAGAAATTCGAGACGCAG
60
TGCTTTGAGGGTTCTCCTG
60
TTACATCGAGGACATCCTGG
59
ATCATCAAACCCTCGAGGC
60
AACCTGGTTTCAGAATCGAC
58
TGCTTTGAGGGTTCTCCTG
60
GGAGAAGAAATTCGAGACGC
59
TGCTTTGAGGGTTCTCCTG
60

转录因子

转录因子

转录因子
影响类型
PubMed链接
HNF4A
Activation
22068426
SLC5A5
Activation
16854221
TLE1
Unknown
15187083

基因本体信息

HHEX基因（以及对应的蛋白质）的细胞分布位置：

[UniProt]     [GenomeNet]

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • 溶酶体
  • 内涵体
  • 细胞核
  • 细胞质
  • 液泡
  • 细胞膜
  • 细胞外基质
  • 内质网
  • 线粒体
  • 高尔基体
  • 细胞骨架

HHEX基因的本体（GO）信息：

GO库代码
对应的蛋白质
来源代码
GO:0003677
F8VU08(UniProtKB)
IEA
GO:0003677
F8VU08(UniProtKB)
IEA
GO:0005634
F8VU08(UniProtKB)
IEA
GO:0000122
Q03014(UniProtKB)
IDA
GO:0000122
Q03014(UniProtKB)
IDA
GO:0000978
Q03014(UniProtKB)
IDA
GO:0001078
Q03014(UniProtKB)
IDA
GO:0001570
Q03014(UniProtKB)
IEA
GO:0001701
Q03014(UniProtKB)
IEA
GO:0002573
Q03014(UniProtKB)
IEA
GO:0003682
Q03014(UniProtKB)
IEA
GO:0005515
Q03014(UniProtKB)
IPI
GO:0005515
Q03014(UniProtKB)
IPI
GO:0005515
Q03014(UniProtKB)
IPI
GO:0005515
Q03014(UniProtKB)
IPI
GO:0005515
Q03014(UniProtKB)
IPI
GO:0005515
Q03014(UniProtKB)
IPI
GO:0005634
Q03014(UniProtKB)
IDA
GO:0005634
Q03014(UniProtKB)
IDA
GO:0005634
Q03014(UniProtKB)
IDA
GO:0005737
Q03014(UniProtKB)
IDA
GO:0005737
Q03014(UniProtKB)
IDA
GO:0006351
Q03014(UniProtKB)
IEA
GO:0006406
Q03014(UniProtKB)
IDA
GO:0007219
Q03014(UniProtKB)
IEA
GO:0007492
Q03014(UniProtKB)
IEA
GO:0008134
Q03014(UniProtKB)
IPI
GO:0008134
Q03014(UniProtKB)
IPI
GO:0008134
Q03014(UniProtKB)
IPI
GO:0008190
Q03014(UniProtKB)
IDA
GO:0008283
Q03014(UniProtKB)
IDA
GO:0008301
Q03014(UniProtKB)
IDA
GO:0009952
Q03014(UniProtKB)
ISS
GO:0010621
Q03014(UniProtKB)
IC
GO:0010944
Q03014(UniProtKB)
TAS
GO:0016055
Q03014(UniProtKB)
IEA
GO:0016525
Q03014(UniProtKB)
ISS
GO:0016973
Q03014(UniProtKB)
IMP
GO:0017025
Q03014(UniProtKB)
TAS
GO:0022027
Q03014(UniProtKB)
IEA
GO:0030154
Q03014(UniProtKB)
IC
GO:0030177
Q03014(UniProtKB)
ISS
GO:0030183
Q03014(UniProtKB)
ISS
GO:0030878
Q03014(UniProtKB)
IEA
GO:0030948
Q03014(UniProtKB)
ISS
GO:0031016
Q03014(UniProtKB)
IEA
GO:0032993
Q03014(UniProtKB)
IDA
GO:0034504
Q03014(UniProtKB)
IDA
GO:0035050
Q03014(UniProtKB)
IEA
GO:0035264
Q03014(UniProtKB)
IEA
GO:0042127
Q03014(UniProtKB)
IEA
GO:0042803
Q03014(UniProtKB)
IPI
GO:0043565
Q03014(UniProtKB)
IDA
GO:0044212
Q03014(UniProtKB)
IDA
GO:0044212
Q03014(UniProtKB)
TAS
GO:0045736
Q03014(UniProtKB)
IDA
GO:0045892
Q03014(UniProtKB)
IDA
GO:0045892
Q03014(UniProtKB)
IDA
GO:0045944
Q03014(UniProtKB)
IDA
GO:0048853
Q03014(UniProtKB)
IEA
GO:0060431
Q03014(UniProtKB)
IEA
GO:0061010
Q03014(UniProtKB)
IEA
GO:0061011
Q03014(UniProtKB)
IEA
GO:0061017
Q03014(UniProtKB)
IEA
GO:0070365
Q03014(UniProtKB)
IEA
GO:0070491
Q03014(UniProtKB)
IDA
GO:0071103
Q03014(UniProtKB)
IDA
GO:0071837
Q03014(UniProtKB)
IEA
GO:0090009
Q03014(UniProtKB)
IEA

基因相互作用关系

基因相互作用关系

基因与其他基因之间的相互作用关系图
序号 作用方式 资源库来源/分值 基因名称 基因名称

基因相关microRNA

基因相关microRNA

可能调控HHEX基因的相关microRNA：     

基因通路图

基因通路图

基因的通路属性图
通路基因列表

基因相关疾病

基因相关疾病

疾病名称 关系值 NofPmids NofSnps 来源
疾病名称 关系值 NofPmids NofSnps 来源
Diabetes Mellitus, Non-Insulin-Dependent 0.213843535 97 39 BeFree_CTD_human_GAD
Fatty Liver 0.12 1 0 CTD_human
Mammary Neoplasms 0.12 1 0 CTD_human
Diabetes Mellitus 0.011096779 9 3 BeFree_GAD
Obesity 0.010553895 7 5 BeFree_GAD
Diabetes Mellitus, Insulin-Dependent 0.005005506 2 0 BeFree_GAD
Alzheimer's Disease 0.004734064 2 0 GAD
Leukemia, Myelocytic, Acute 0.00272435 1 0 LHGDN
Polycystic Ovary Syndrome 0.002638474 1 0 BeFree_GAD
Impaired glucose tolerance 0.002638474 2 5 BeFree_GAD
Atherosclerosis 0.002367032 1 0 GAD
Calcinosis 0.002367032 1 0 GAD
Coronary heart disease 0.002367032 1 0 GAD
Endometrial Neoplasms 0.002367032 1 0 GAD
Fetal Diseases 0.002367032 1 0 GAD
HIV Infections 0.002367032 1 0 GAD
Hyperglycemia 0.002367032 1 0 GAD
Insulin Resistance 0.002367032 1 0 GAD
Multiple Sclerosis 0.002367032 1 1 GAD
Starvation 0.002367032 1 0 GAD
Malnutrition 0.002367032 1 0 GAD
Coronary Artery Disease 0.002367032 1 0 GAD
Diabetes 0.001628651 6 3 BeFree
Tay-Sachs Disease 0.001085767 4 0 BeFree
Carcinogenesis 0.000542884 2 0 BeFree
Anaplasia 0.000271442 1 0 BeFree
Malignant neoplasm of breast 0.000271442 1 0 BeFree
Malignant neoplasm of thyroid 0.000271442 1 0 BeFree
Congenital Hypothyroidism 0.000271442 1 0 BeFree
Ovarian Diseases 0.000271442 1 0 BeFree
Sezary Syndrome 0.000271442 1 0 BeFree
Thyroid Neoplasm 0.000271442 1 0 BeFree
Gestational Diabetes 0.000271442 1 6 BeFree
Thyroid Gland Follicular Adenoma 0.000271442 1 0 BeFree
Undifferentiated carcinoma 0.000271442 1 0 BeFree
Gangliosidoses, GM2 0.000271442 1 0 BeFree
Endemic Cretinism 0.000271442 1 0 BeFree
Alzheimer Disease, Late Onset 0.000271442 1 0 BeFree
Overweight 0.000271442 1 0 BeFree
Metabolic Syndrome X 0.000271442 1 2 BeFree
Thyroid carcinoma 0.000271442 1 0 BeFree
Leukemogenesis 0.000271442 1 0 BeFree
Breast Carcinoma 0.000271442 1 0 BeFree
Epithelioma 0.000271442 1 0 BeFree
Cardiomyopathy, Familial Idiopathic 0.000271442 1 0 BeFree

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