RBP4(retinol binding protein 4, plasma) 转至新版数据库

基因基本信息

基因基本信息

基因简称(symbol)
    [HGNC]     [GeneCards]     [NCBI]
基因种类(locus group)
同源简称(alias symbol)
基因家族代码(gene_family_id)
    [HGNC]     [GenScript]
omim代码
entrez码
    [Vega]
vega基因码
ensembl基因码
    [Ensembl]
基因家族(gene family)
refseq数据库代号

更多...

基因种类(locus_type)
基因名称状态(status)
location_sortable
同源基因名称(alias name)
基因名称批准使用时间(date_approved_reserved)
基因简称更名时间(date_symbol_changed)
基因名称更名时间(date_name_changed)
更新时间(date_modified)
ucsc码
ena
ccds数据码
uniprot数据码
pubmed代码
mgd码
rgd码
生命科学数据库(lsdb)
更新时间(date modified)
cosmic
mirbase
基因曾用简称(prev symbol)
基因曾用名称(prev name)
homeodb
cosmic
snornabase
bioparadigms slc
orphanet
假基因信息(pseudogeneorg)
horde id
merops
imgt
iuphar
kznf基因类别
mamit-trnadb
cd
LncRNA数据库
酶代码
中间纤维数据库

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基因染色体位置

基因染色体位置

10q23.33
基因染色体位置图

基因简述

基因简述

This protein belongs to the lipocalin family and is the specific carrier for retinol (vitamin A alcohol) in the blood. It delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin which prevents its loss by filtration through the kidney glomeruli. A deficiency of vitamin A blocks secretion of the binding protein posttranslationally and results in defective delivery and supply to the epidermal cells. [provided by RefSeq, Jul 2008]

[中文简述(自动翻译):]  这种蛋白质属于脂笼蛋白家族并且是视黄醇在血液中的特定载波（维生素A醇）。它从肝脏存储到周围组织提供视黄醇。在血浆中，RBP-视黄醇复合物与甲状腺素运载它通过肾小球防止其损失过滤交互。的维生素A块结合蛋白翻译后，并在有缺陷的和供给表皮细胞的结果分泌A缺乏症。 [由RefSeq的，2008年7月提供]

OMIM数据库中对RBP4基因的介绍     Wikipedia数据库中对RBP4基因的介绍

基因序列

基因序列

RBP4基因的碱基序列：[NCBI]

基因突变

基因突变

RBP4基因的碱基突变：           显示全部snp
rs1060633       rs3758537       rs3758538       rs3758539       rs7070492       rs7070884       rs7079946       rs7091052       rs7094671       rs7099587       rs7895772       rs10882275       rs10882276       rs10882277       rs10882278       rs10882279       rs10882280       rs10882281       rs10882282       rs10882283       rs11187542       rs11187543       rs11187544       rs11187545       rs11187546       rs11187547       rs11187548       rs11546956       rs12217985       rs12220124       rs12265684       rs12768100       rs13376735       rs13376835       rs13376858       rs17108990       rs17108991      
rs28383574       rs34571439       rs34812400       rs35431690       rs35580950       rs36014035       rs36035572       rs36077620       rs55684241       rs55964695       rs56057449       rs56401591       rs57029781       rs57032472       rs57477607       rs58333627       rs58621997       rs61461737       rs61866613       rs66697381       rs68133882       rs72820978       rs73327272       rs73327273       rs73327278       rs73327281       rs73327285       rs74150279       rs74150280       rs74150281       rs74150282       rs74356785       rs74514449       rs74592273       rs74599191       rs75130970       rs75368895       rs76177518       rs76473948       rs76553992       rs76582050       rs76744432       rs76767084       rs76899699       rs76925335       rs76952744       rs76999824       rs77143588       rs77196820       rs77676617       rs78210870       rs78323310       rs78380903       rs78532348       rs78597502       rs78853772       rs79168396       rs80297347       rs111558782       rs111785373       rs112385876       rs112666890       rs112685242       rs112715571       rs112811136       rs113069478       rs113634662       rs113639456       rs113693473       rs113712384       rs114007959       rs114161724       rs114273007       rs114294874       rs115120975       rs115185967       rs115334874       rs115754552       rs115968880       rs115984006       rs116159214       rs116228045       rs116708099       rs116736522       rs116762988       rs116887052       rs117558315       rs138317894       rs138581612       rs138732259       rs139133636       rs139153768       rs139534453       rs139973394       rs139995337       rs140236831       rs140847127       rs141474968       rs141732528       rs142149253       rs142574624       rs142697124       rs143699999       rs143827661       rs143895771       rs144281277       rs144571071       rs145044751       rs145300948       rs145586133       rs145814965       rs146011548       rs146023709       rs146185409       rs146411448       rs146461854       rs147744909       rs148120389       rs148143111       rs148416658       rs148471776       rs148948494       rs149091963       rs150234653       rs150540008       rs150760117       rs151192231       rs180976304       rs181286495       rs181338342       rs181635654       rs181953252       rs183015671       rs183146433       rs183352805       rs183371664       rs183653001       rs184052539       rs184242806       rs185143483       rs185714192       rs185899691       rs185900203       rs186438305       rs186523197       rs187556252       rs188499508       rs188535578       rs188951347       rs189196082       rs189443464       rs190236606       rs190547734       rs190808621       rs190816373       rs190910049       rs191314085       rs191355890       rs191747796       rs192339373       rs192522468       rs192838885       rs199767234       rs200234502       rs200867321       rs200974617       rs201268813       rs201407285       rs202087238       rs202140213       rs367834906       rs368542314       rs368789793       rs368838780       rs368943307       rs369036602       rs369214755       rs369264892       rs369378480       rs369460388       rs369560070       rs370358940       rs370761315       rs371394529       rs372010388       rs372328986       rs372763506       rs372913305       rs373058806       rs373070201       rs373606069       rs373896042       rs373932035       rs374211472       rs374519908       rs374532803       rs374537942       rs374608815       rs374650128       rs374987431       rs375067243       rs375203480       rs376084501       rs376337066       rs376688143       rs377206816       rs527923545       rs527953304       rs528051459       rs529110632       rs529132743       rs529161250       rs529209758       rs529305599       rs529489441       rs530483954       rs530544269       rs530856532       rs530912086       rs531645000       rs531706535       rs531783744       rs531789471       rs531988058       rs532171332       rs532309532       rs533046603       rs533154641       rs533213284       rs533598754       rs533843571       rs534499977       rs534561771       rs534671062       rs534692833       rs535183131       rs535640190       rs535640335       rs535700155       rs535723429       rs535915601       rs536325499       rs536461847       rs536833266       rs536893312       rs536910771       rs537444538       rs538113392       rs538648399       rs538690239       rs539317329       rs539515103       rs539650500       rs539921676       rs540062466       rs540429767       rs541450077       rs541488632       rs541560105       rs541644412       rs541655033       rs542132723       rs542602683       rs542612819       rs542737876       rs542825790       rs542855487       rs542970357       rs543276795       rs543805772       rs544005959       rs544020087       rs544020389       rs545008394       rs545180983       rs545288670       rs545316346       rs546326061       rs546473021       rs546549435       rs546609913       rs546971491       rs547376657       rs547873944       rs547997233       rs548302291       rs548637791       rs549179101       rs549818745       rs550290929       rs550341949       rs550503723       rs550521406       rs550836551       rs551011235       rs551031018       rs551112180       rs551565896       rs551893032       rs552084591       rs553250709       rs553299253       rs553556015       rs553615340       rs553625904       rs553956647       rs554419198       rs554481794       rs555075418       rs555084762       rs555621014       rs555682754       rs556149374       rs556273341       rs556290559       rs556817192       rs556817286       rs557522647       rs557535231       rs557609728       rs557612902       rs557753956       rs558560244       rs559772068       rs560079036       rs560353785       rs560465876       rs561068753       rs561206007       rs561316976       rs561450671       rs561499123       rs561573001       rs562033717       rs562190350       rs562625484       rs562762715       rs563068457       rs563824678       rs563825389       rs563884646       rs564017303       rs564101819       rs564200836       rs565082163       rs565173496       rs565633983       rs565892210       rs566105470       rs566759714       rs566762577       rs566841927       rs566948912       rs567298588       rs567942248       rs568023272       rs568054670       rs568435890       rs569156024       rs569274853       rs569458335       rs569527449       rs569766080       rs570654697       rs570735801       rs570855866       rs570934099       rs571009649       rs571200544       rs571248565       rs571269627       rs571838051       rs572174763       rs572433906       rs572520459       rs572545519       rs572642000       rs573730975       rs573775800       rs573870964       rs574006118       rs574389273       rs574486887       rs574651184       rs575021397       rs575043390       rs575162786       rs576064979       rs576418153       rs576482695       rs577416561       rs577540732       rs577594120       rs577617221       rs577798908       rs745311732       rs745399445       rs745529247       rs746004782       rs746638115       rs746669893       rs746741751       rs747059731       rs747468011       rs747664192       rs748116788       rs748191976       rs748422517       rs748595106       rs748737715       rs748825583       rs749329416       rs749469951       rs749591625       rs749859880       rs749972683       rs750296456       rs750356617       rs750444432       rs750535264       rs750764953       rs751014897       rs751433559       rs751643857       rs752169390       rs752204198       rs752379212       rs752565532       rs752939815       rs753226964       rs753316448       rs753409149       rs753671270       rs753776893       rs753792133       rs753882149       rs753884886       rs753891505       rs754220609       rs754347794       rs754634126       rs755349479       rs755814837       rs755900911       rs756079535       rs756433072       rs756531955       rs756699910       rs756894160       rs756895115       rs757077488       rs757269973       rs757592156       rs757824484       rs758050576       rs758073926       rs758074878       rs758254462       rs758370370       rs758640008       rs759129264       rs759375642       rs759451936       rs759490328       rs759574331       rs759658493       rs759820276       rs760023034       rs760138406       rs760604288       rs760990155       rs761076526       rs761388371       rs761576794       rs761742578       rs761838369       rs762114740       rs762366597       rs762593323       rs762620416       rs762684470       rs763061570       rs763442047       rs763758307       rs763976042       rs764165063       rs764172344       rs764527292       rs764772453       rs764878468       rs765499399       rs765796139       rs766167167       rs766365350       rs766445558       rs766637975       rs766813940       rs767571686       rs767751790       rs767992165       rs768507461       rs768523775       rs769033053       rs769248272       rs769917680       rs769975887       rs770114862       rs770175317       rs770310391       rs770539112       rs770647249       rs771265283       rs771463174       rs771687943       rs771831518       rs772011650       rs772097627       rs772199802       rs772637305       rs772902279       rs773146117       rs773419725       rs773522695       rs773644215       rs773687648       rs773777925       rs774027887       rs774297883       rs774496890       rs774499228       rs774794353       rs774876327       rs775357336       rs775444964       rs775550438       rs775648139       rs775846026       rs776000321       rs776405147       rs776583959       rs776942406       rs777062715       rs777065564       rs777072387       rs777433708       rs777620177       rs778127147       rs778184050       rs778553827       rs778748029       rs778924032       rs779153292       rs779167180       rs779231863       rs779512194       rs779604024       rs779798755       rs779810036       rs780211759       rs780277648       rs780658173       rs780950382       rs781030294       rs781035891       rs781436011      

基因表达

基因表达

RBP4基因在不同组织中的表达：    [UniProt]

基因在不同组织中的表达图

基因引物

基因引物

正向引物序列
正向引物Tm值
反向引物序列
反向引物Tm值
rank
CGCAGAAGATTGTAAGGCAG
59
CATCGCAGTAACCGTTGTG
60
CGCAGAAGATTGTAAGGCAG
59
CATCGCAGTAACCGTTGTG
60
CAGAAGATTGTAAGGCAGCG
59
CATCGCAGTAACCGTTGTG
60
CGCAGAAGATTGTAAGGCAG
59
CATCGCAGTAACCGTTGTG
60
CAGAAGATTGTAAGGCAGCG
59
CATCGCAGTAACCGTTGTG
60
CGCAGAAGATTGTAAGGCAG
59
CATCGCAGTAACCGTTGTG
60
GCAGAAGATTGTAAGGCAGC
60
CATCGCAGTAACCGTTGTG
60
GCAGAAGATTGTAAGGCAGC
60
CATCGCAGTAACCGTTGTG
60
CAGAAGATTGTAAGGCAGCG
59
CATCGCAGTAACCGTTGTG
60
CAGAAGATTGTAAGGCAGCG
59
CATCGCAGTAACCGTTGTG
60

转录因子

转录因子

      尚未收录相关数据

基因本体信息

RBP4基因（以及对应的蛋白质）的细胞分布位置：

[UniProt]     [GenomeNet]

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • 溶酶体
  • 内涵体
  • 细胞核
  • 细胞质
  • 液泡
  • 细胞膜
  • 细胞外基质
  • 内质网
  • 线粒体
  • 高尔基体
  • 细胞骨架

RBP4基因的本体（GO）信息：

GO库代码
对应的蛋白质
来源代码
GO:0005215
A0A0C4DGV7(UniProtKB)
IEA
GO:0005501
A0A0C4DGV7(UniProtKB)
IEA
GO:0005576
A0A0C4DGV7(UniProtKB)
IEA
GO:0006810
A0A0C4DGV7(UniProtKB)
IEA
GO:0036094
A0A0C4DGV7(UniProtKB)
IEA
GO:0001523
P02753(UniProtKB)
TAS
GO:0001523
P02753(UniProtKB)
TAS
GO:0001654
P02753(UniProtKB)
ISS
GO:0001654
P02753(UniProtKB)
IMP
GO:0005515
P02753(UniProtKB)
IPI
GO:0005515
P02753(UniProtKB)
IPI
GO:0005515
P02753(UniProtKB)
IPI
GO:0005576
P02753(UniProtKB)
TAS
GO:0005576
P02753(UniProtKB)
TAS
GO:0005576
P02753(UniProtKB)
TAS
GO:0005576
P02753(UniProtKB)
TAS
GO:0005576
P02753(UniProtKB)
TAS
GO:0005615
P02753(UniProtKB)
ISS
GO:0005615
P02753(UniProtKB)
IDA
GO:0005615
P02753(UniProtKB)
IDA
GO:0005829
P02753(UniProtKB)
TAS
GO:0006094
P02753(UniProtKB)
ISS
GO:0006094
P02753(UniProtKB)
IMP
GO:0007507
P02753(UniProtKB)
ISS
GO:0007601
P02753(UniProtKB)
IEA
GO:0016918
P02753(UniProtKB)
IEA
GO:0019841
P02753(UniProtKB)
IDA
GO:0030277
P02753(UniProtKB)
IDA
GO:0030324
P02753(UniProtKB)
ISS
GO:0032024
P02753(UniProtKB)
IMP
GO:0032526
P02753(UniProtKB)
IDA
GO:0034632
P02753(UniProtKB)
IC
GO:0034633
P02753(UniProtKB)
IC
GO:0042572
P02753(UniProtKB)
IMP
GO:0042593
P02753(UniProtKB)
IDA
GO:0043234
P02753(UniProtKB)
IEA
GO:0045471
P02753(UniProtKB)
IEA
GO:0046982
P02753(UniProtKB)
IEA
GO:0048562
P02753(UniProtKB)
ISS
GO:0048706
P02753(UniProtKB)
ISS
GO:0048738
P02753(UniProtKB)
ISS
GO:0048807
P02753(UniProtKB)
ISS
GO:0051024
P02753(UniProtKB)
ISS
GO:0060044
P02753(UniProtKB)
ISS
GO:0060059
P02753(UniProtKB)
ISS
GO:0060065
P02753(UniProtKB)
ISS
GO:0060068
P02753(UniProtKB)
ISS
GO:0060157
P02753(UniProtKB)
ISS
GO:0060347
P02753(UniProtKB)
ISS
GO:0070062
P02753(UniProtKB)
IDA
GO:0070062
P02753(UniProtKB)
IDA
GO:0070062
P02753(UniProtKB)
IDA
GO:0005215
Q5VY30(UniProtKB)
IEA
GO:0005501
Q5VY30(UniProtKB)
IEA
GO:0005576
Q5VY30(UniProtKB)
IEA
GO:0006810
Q5VY30(UniProtKB)
IEA
GO:0036094
Q5VY30(UniProtKB)
IEA

基因相互作用关系

基因相互作用关系

基因与其他基因之间的相互作用关系图
序号 作用方式 资源库来源/分值 基因名称 基因名称

基因相关microRNA

基因相关microRNA

可能调控RBP4基因的相关microRNA：     

基因通路图

基因通路图

基因的通路属性图
通路基因列表

基因相关疾病

基因相关疾病

疾病名称 关系值 NofPmids NofSnps 来源
疾病名称 关系值 NofPmids NofSnps 来源
RETINAL DYSTROPHY, IRIS COLOBOMA, AND COMEDOGENIC ACNE SYNDROME 0.36 1 3 CLINVAR_ORPHANET_UNIPROT
Polycystic Ovary Syndrome 0.125720142 2 0 BeFree_CTD_human_LHGDN
Vitamin A Deficiency 0.120271442 2 0 BeFree_CTD_human
Spontaneous abortion 0.12 1 0 CTD_human
Kidney Diseases 0.12 1 0 CTD_human
Alcoholic Liver Diseases 0.12 1 0 CTD_human
Animal Mammary Neoplasms 0.12 1 0 CTD_human
Mammary Neoplasms, Experimental 0.12 1 0 CTD_human
Necrosis 0.12 1 0 CTD_human
Stomach Neoplasms 0.12 1 0 CTD_human
Keratomalacia 0.12 1 0 CTD_human
Diabetes Mellitus, Non-Insulin-Dependent 0.097535439 22 1 BeFree_GAD_RGD
Obesity 0.086514605 25 2 BeFree_RGD
Cardiovascular Diseases 0.006263026 5 0 BeFree_LHGDN
Gestational Diabetes 0.006263026 5 0 BeFree_LHGDN
Hypertriglyceridemia 0.005091382 2 0 GAD_LHGDN
Metabolic Syndrome X 0.004810009 9 0 BeFree_GAD
Impaired glucose tolerance 0.004353001 7 1 BeFree_LHGDN
Hepatitis C, Chronic 0.003267234 2 0 BeFree_LHGDN
Diabetic Nephropathy 0.00272435 1 0 LHGDN
Fatty Liver 0.00272435 1 0 LHGDN
Hypothyroidism 0.00272435 1 0 LHGDN
Liver Cirrhosis 0.00272435 1 0 LHGDN
Amyloid Neuropathies 0.00272435 1 0 LHGDN
Diabetes 0.002442977 9 0 BeFree
Diabetes Mellitus 0.002442977 9 0 BeFree
Alzheimer's Disease 0.002367032 1 0 GAD
Insulin Resistance 0.002367032 1 0 GAD
Hypertriglyceridemia result 0.002367032 1 0 GAD
Metabolic Diseases 0.001085767 4 0 BeFree
Carcinogenesis 0.001085767 4 0 BeFree
Liver carcinoma 0.001085767 4 0 BeFree
Non-alcoholic Fatty Liver Disease 0.000814326 3 0 BeFree
Amyotrophic Lateral Sclerosis 0.000542884 2 0 BeFree
Coronary Arteriosclerosis 0.000542884 2 0 BeFree
Coronary heart disease 0.000542884 2 0 BeFree
Liver neoplasms 0.000542884 2 0 BeFree
Coronary Artery Disease 0.000542884 2 0 BeFree
Anemia 0.000271442 1 0 BeFree
Arteriosclerosis 0.000271442 1 0 BeFree
Atherosclerosis 0.000271442 1 0 BeFree
Malignant tumor of cervix 0.000271442 1 0 BeFree
Diabetes Mellitus, Insulin-Dependent 0.000271442 1 0 BeFree
Diabetic Retinopathy 0.000271442 1 0 BeFree
Down Syndrome 0.000271442 1 0 BeFree
Disorder of eye 0.000271442 1 0 BeFree
Glioblastoma 0.000271442 1 0 BeFree
Hepatitis C 0.000271442 1 0 BeFree
Hirschsprung Disease 0.000271442 1 0 BeFree
HIV Infections 0.000271442 1 0 BeFree
Hyperinsulinism 0.000271442 1 0 BeFree
Hypertension, Portal 0.000271442 1 0 BeFree
Adult T-Cell Lymphoma/Leukemia 0.000271442 1 0 BeFree
Malignant neoplasm of stomach 0.000271442 1 0 BeFree
Ovarian Carcinoma 0.000271442 1 0 BeFree
Ovarian Diseases 0.000271442 1 0 BeFree
Retinal Degeneration 0.000271442 1 0 BeFree
Retinal Diseases 0.000271442 1 0 BeFree
Skin Neoplasms 0.000271442 1 0 BeFree
Thalassemia 0.000271442 1 0 BeFree
Vascular Diseases 0.000271442 1 0 BeFree
Proliferative diabetic retinopathy 0.000271442 1 0 BeFree
Retinal damage 0.000271442 1 0 BeFree
Fibrosis, Liver 0.000271442 1 0 BeFree
Dyslipidemias 0.000271442 1 0 BeFree
Cancer of Head and Neck 0.000271442 1 2 BeFree
Cervix carcinoma 0.000271442 1 0 BeFree
Chronic liver disease 0.000271442 1 0 BeFree
Acquired Fanconi syndrome 0.000271442 1 0 BeFree
Prediabetes syndrome 0.000271442 1 0 BeFree
Malignant neoplasm of prostate 0.000271442 1 0 BeFree
Alzheimer Disease, Late Onset 0.000271442 1 0 BeFree
Overweight 0.000271442 1 0 BeFree
Neurodegenerative Disorders 0.000271442 1 0 BeFree
Prostate carcinoma 0.000271442 1 0 BeFree
Stomach Carcinoma 0.000271442 1 0 BeFree
Chronic lung disease 0.000271442 1 0 BeFree
Retinal Dystrophies 0.000271442 1 0 BeFree
Dent's disease 0.000271442 1 0 BeFree
Vascular inflammations 0.000271442 1 0 BeFree
Malignant neoplasm of ovary 0.000271442 1 0 BeFree
Primary Effusion Lymphoma 0.000271442 1 0 BeFree
Cirrhosis 0.000271442 1 0 BeFree
ANOPHTHALMIA AND PULMONARY HYPOPLASIA 0.000271442 1 0 BeFree
Obesity, Visceral 0.000271442 1 0 BeFree
Nonalcoholic Steatohepatitis 0.000271442 1 0 BeFree
Unspecified visual loss 0.000271442 1 0 BeFree

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