POU3F2(POU class 3 homeobox 2) 转至新版数据库

基因基本信息

基因基本信息

基因简称(symbol)
    [HGNC]     [GeneCards]     [NCBI]
基因种类(locus group)
同源简称(alias symbol)
基因家族代码(gene_family_id)
    [HGNC]     [GenScript]
omim代码
entrez码
    [Vega]
vega基因码
ensembl基因码
    [Ensembl]
基因家族(gene family)
refseq数据库代号

更多...

基因种类(locus_type)
基因名称状态(status)
location_sortable
同源基因名称(alias name)
基因名称批准使用时间(date_approved_reserved)
基因简称更名时间(date_symbol_changed)
基因名称更名时间(date_name_changed)
更新时间(date_modified)
ucsc码
ena
ccds数据码
uniprot数据码
pubmed代码
mgd码
rgd码
生命科学数据库(lsdb)
更新时间(date modified)
cosmic
mirbase
基因曾用简称(prev symbol)
基因曾用名称(prev name)
homeodb
cosmic
snornabase
bioparadigms slc
orphanet
假基因信息(pseudogeneorg)
horde id
merops
imgt
iuphar
kznf基因类别
mamit-trnadb
cd
LncRNA数据库
酶代码
中间纤维数据库

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基因染色体位置

基因染色体位置

6q16.2
基因染色体位置图

基因简述

基因简述

This gene encodes a member of the POU-III class of neural transcription factors. The encoded protein is involved in neuronal differentiation and enhances the activation of corticotropin-releasing hormone regulated genes. Overexpression of this protein is associated with an increase in the proliferation of melanoma cells. [provided by RefSeq, Mar 2012]

[中文简述(自动翻译):]  该基因编码的POU-III类神经转录因子的成员。所编码的蛋白质是参与神经元分化和增强的促肾上腺皮质激素释放激素调节的基因的活化。这种蛋白质的过量表达与增加的黑色素瘤细胞的增殖相关。 [由RefSeq的，2012年3月提供]

OMIM数据库中对POU3F2基因的介绍     Wikipedia数据库中对POU3F2基因的介绍

基因序列

基因序列

POU3F2基因的碱基序列：[NCBI]

基因突变

基因突变

POU3F2基因的碱基突变：           显示全部snp
rs195860       rs195861       rs195862       rs3823036       rs5878562       rs9372956       rs9398940       rs11968822       rs12665323       rs13209138       rs13209154       rs13212364       rs33999841       rs34400185       rs34687300       rs35051628       rs56318724       rs62423591       rs66683016       rs71545770       rs71545771       rs71564255       rs73501598       rs73759365       rs77120481       rs77971107       rs79209351       rs79339339       rs79872709       rs111234726       rs111398084       rs113027329       rs114426699       rs116999381       rs138384155       rs140240061       rs140334167      
rs144504012       rs145198575       rs147437170       rs150077448       rs182079068       rs183853037       rs185412225       rs186667950       rs187177491       rs187647254       rs190040379       rs191148125       rs191299683       rs192443961       rs192631653       rs193052910       rs199873673       rs200105737       rs200105843       rs200533700       rs200874161       rs201781902       rs202224147       rs202228843       rs367580619       rs367612148       rs369383182       rs369811680       rs370268369       rs370325099       rs371461013       rs371685985       rs371856505       rs373455300       rs375953848       rs375972837       rs376966559       rs377608434       rs528333665       rs528356783       rs528372381       rs528652938       rs528961528       rs528975489       rs529442854       rs530140606       rs530156320       rs530383046       rs532298489       rs532674586       rs532720607       rs532806426       rs533648108       rs533797850       rs534153465       rs534739927       rs534761304       rs535131130       rs535380938       rs535875616       rs535980443       rs536273706       rs536885615       rs536962188       rs537249567       rs537293133       rs537757012       rs538054465       rs539068250       rs539364587       rs540232403       rs540505046       rs540543714       rs540731875       rs541408992       rs541617191       rs541958699       rs542247520       rs542879776       rs543196811       rs543563712       rs544059334       rs544464563       rs545685295       rs545778736       rs546800926       rs547160834       rs548264769       rs548969679       rs549102513       rs549612488       rs550416789       rs550762944       rs550949272       rs551309902       rs552686016       rs553422244       rs553460902       rs553826397       rs554918739       rs555285288       rs555623496       rs556374058       rs556732734       rs557369736       rs558605961       rs558750380       rs558925724       rs559022018       rs561021011       rs561268251       rs561553107       rs562830822       rs563025383       rs563466161       rs563886177       rs563923322       rs564719242       rs565175148       rs565665584       rs565789354       rs566499439       rs566556863       rs567323475       rs568142974       rs568570734       rs568612593       rs569128447       rs569607118       rs570717366       rs571759235       rs572187565       rs573432263       rs573998732       rs574066580       rs574390649       rs574594619       rs575236029       rs575240654       rs575798737       rs576992478       rs577149340       rs577299542       rs578070886       rs745337431       rs745693384       rs745783228       rs745999260       rs746352049       rs746735872       rs747013914       rs747431344       rs747515151       rs747795763       rs748117807       rs748122721       rs748495029       rs748500022       rs748734621       rs748744954       rs748832920       rs748922436       rs749143343       rs749518371       rs749593813       rs749945303       rs750080952       rs750643097       rs750728970       rs750908730       rs751058060       rs751441652       rs751701736       rs751804272       rs751975215       rs752078456       rs752142136       rs752519309       rs752607175       rs752836778       rs753233862       rs753609966       rs753914866       rs754005443       rs754333102       rs754504407       rs754868893       rs754989117       rs755239626       rs755565285       rs755871716       rs756228158       rs756316047       rs756479637       rs756498791       rs756856767       rs756884771       rs757384036       rs757489705       rs757598374       rs757811015       rs757962884       rs758048851       rs758483177       rs758669972       rs759175261       rs759421535       rs759775933       rs759992003       rs760060591       rs760516943       rs760608547       rs761082680       rs761254912       rs761363151       rs761574545       rs761639644       rs761948320       rs762013289       rs762236131       rs762710758       rs762798701       rs762991500       rs763126187       rs763367137       rs763454533       rs763869124       rs763958815       rs764356762       rs764366792       rs764454386       rs764713551       rs764851446       rs765077394       rs766081561       rs766174330       rs766389803       rs766725738       rs766738537       rs767049661       rs767392491       rs767482212       rs767755714       rs767818457       rs768316028       rs768389252       rs768623573       rs769130084       rs769221931       rs769369597       rs769802686       rs769938601       rs770001103       rs770323148       rs770835443       rs770981201       rs771011381       rs771072735       rs771499170       rs771563849       rs772071914       rs772183832       rs772489128       rs772576024       rs772721593       rs772816071       rs773083837       rs773185617       rs773452318       rs773775751       rs774123151       rs774389211       rs774425066       rs774687168       rs774976844       rs775075666       rs775085214       rs775815466       rs775918614       rs776023246       rs776056411       rs776503278       rs776612813       rs776646065       rs776972819       rs777060780       rs777362525       rs777447703       rs777913397       rs777914698       rs778009082       rs778199916       rs778590439       rs778860491       rs779038428       rs779079741       rs779168236       rs779716327       rs779817958       rs779917134       rs780100752       rs780196287       rs780679865       rs780854227       rs780956589       rs781220601       rs781334524       rs781662211       rs781693832       rs781702109      

基因表达

基因表达

POU3F2基因在不同组织中的表达：    [UniProt]

基因在不同组织中的表达图

基因引物

基因引物

正向引物序列
正向引物Tm值
反向引物序列
反向引物Tm值
rank
TGAACAAGTGGTTGGAGGA
59
ATCTTGTCTATGCTCGTGGG
60
TTGAACAAGTGGTTGGAGG
58
TCTTGTCTATGCTCGTGGG
59
TGAACAAGTGGTTGGAGGA
59
ATCTTGTCTATGCTCGTGG
57

转录因子

转录因子

转录因子
影响类型
PubMed链接
CDH13
Unknown
23069940
DDC
Unknown
9602135
FABP7
Unknown
21771320
FOXP2
Unknown
23197593
GNRH1
Activation
11875100
MITF
Unknown
18628967
NKX2-1
Unknown
23358112
PAX3
Unknown
22290434
PDE5A
Repression
21215707

基因本体信息

POU3F2基因（以及对应的蛋白质）的细胞分布位置：

[UniProt]     [GenomeNet]

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • 溶酶体
  • 内涵体
  • 细胞核
  • 细胞质
  • 液泡
  • 细胞膜
  • 细胞外基质
  • 内质网
  • 线粒体
  • 高尔基体
  • 细胞骨架

POU3F2基因的本体（GO）信息：

GO库代码
对应的蛋白质
来源代码
GO:0000978
P20265(UniProtKB)
IEA
GO:0001077
P20265(UniProtKB)
IEA
GO:0001105
P20265(UniProtKB)
IEA
GO:0003700
P20265(UniProtKB)
TAS
GO:0003700
P20265(UniProtKB)
TAS
GO:0005515
P20265(UniProtKB)
IPI
GO:0005515
P20265(UniProtKB)
IPI
GO:0005515
P20265(UniProtKB)
IPI
GO:0005515
P20265(UniProtKB)
IPI
GO:0005634
P20265(UniProtKB)
IEA
GO:0005667
P20265(UniProtKB)
IEA
GO:0006366
P20265(UniProtKB)
IEA
GO:0008284
P20265(UniProtKB)
IDA
GO:0008544
P20265(UniProtKB)
IEA
GO:0010629
P20265(UniProtKB)
IEA
GO:0014002
P20265(UniProtKB)
IEA
GO:0021799
P20265(UniProtKB)
IEA
GO:0021869
P20265(UniProtKB)
IEA
GO:0021979
P20265(UniProtKB)
IEA
GO:0021985
P20265(UniProtKB)
IEA
GO:0022011
P20265(UniProtKB)
IEA
GO:0030182
P20265(UniProtKB)
IEA
GO:0040018
P20265(UniProtKB)
IEA
GO:0042802
P20265(UniProtKB)
IPI
GO:0045944
P20265(UniProtKB)
IEA
GO:0050770
P20265(UniProtKB)
IEA
GO:0071310
P20265(UniProtKB)
IEA

基因相互作用关系

基因相互作用关系

基因与其他基因之间的相互作用关系图
序号 作用方式 资源库来源/分值 基因名称 基因名称

基因相关microRNA

基因相关microRNA

可能调控POU3F2基因的相关microRNA：     

基因通路图

基因通路图

基因的通路属性图
通路基因列表

基因相关疾病

基因相关疾病

疾病名称 关系值 NofPmids NofSnps 来源
疾病名称 关系值 NofPmids NofSnps 来源
melanoma 0.010606096 19 0 BeFree_LHGDN
Schizophrenia 0.002638474 2 0 BeFree_GAD
Microphthalmos 0.000542884 2 0 BeFree
Neoplasm Metastasis 0.000542884 2 0 BeFree
Small cell carcinoma of lung 0.000542884 2 0 BeFree
Malignant neoplasm of lung 0.000542884 2 0 BeFree
Carcinoma of lung 0.000542884 2 0 BeFree
Bipolar Disorder 0.000271442 1 0 BeFree
Merkel cell carcinoma 0.000271442 1 0 BeFree
Congenital chromosomal disease 0.000271442 1 0 BeFree
Atrial Septal Defects 0.000271442 1 0 BeFree
Lung Neoplasms 0.000271442 1 0 BeFree
Multiple Endocrine Neoplasia Type 1 0.000271442 1 0 BeFree
Severe Combined Immunodeficiency 0.000271442 1 0 BeFree
Autism Spectrum Disorders 0.000271442 1 0 BeFree

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