REG3A基因详情-基因数据库-基因云馆

REG3A(regenerating islet-derived 3 alpha) 转至新版数据库

基因简称(symbol)

REG3A [HGNC] [GeneCards] [NCBI]

基因种类(locus group)

protein-coding gene

同源简称(alias symbol)

HIP|REG-III|REG3|PBCGF|PAP1

基因家族代码(gene_family_id)

[HGNC] [GenScript]

omim代码

167805

entrez码

5068 [Vega]

vega基因码

OTTHUMG00000130017

ensembl基因码

ENSG00000172016 [Ensembl]

基因家族(gene family)

refseq数据库代号

NM_002580

更多...

基因种类(locus_type)

gene with protein product

基因名称状态(status)

Approved

location_sortable

02p12

同源基因名称(alias name)

基因名称批准使用时间(date_approved_reserved)

1993-09-20T00:00:00Z

基因简称更名时间(date_symbol_changed)

2005-02-11T00:00:00Z

基因名称更名时间(date_name_changed)

2005-02-11T00:00:00Z

更新时间(date_modified)

2014-11-18T00:00:00Z

ucsc码

uc002sof.2

ena

S51768

ccds数据码

CCDS1965

uniprot数据码

Q06141

pubmed代码

8188210

mgd码

MGI:109408

rgd码

RGD:3254

生命科学数据库(lsdb)

更新时间(date modified)

2014-11-18T00:00:00Z

cosmic

REG3A

mirbase

基因曾用简称(prev symbol)

PAP

基因曾用名称(prev name)

pancreatitis-associated protein

homeodb

cosmic

REG3A

snornabase

bioparadigms slc

orphanet

假基因信息(pseudogeneorg)

horde id

merops

imgt

iuphar

kznf基因类别

mamit-trnadb

cd

LncRNA数据库

酶代码

中间纤维数据库

收起

2p12

This gene encodes a pancreatic secretory protein that may be involved in cell proliferation or differentiation. It has similarity to the C-type lectin superfamily. The enhanced expression of this gene is observed during pancreatic inflammation and liver carcinogenesis. The mature protein also functions as an antimicrobial protein with antibacterial activity. Alternate splicing results in multiple transcript variants that encode the same protein.[provided by RefSeq, Nov 2014]

[中文简述(自动翻译):] 这个基因编码可能参与细胞增殖或分化胰腺分泌蛋白。它具有相似的C型凝集素超家族。胰炎和肝脏发生过程中增强该基因的表达被观察到。成熟的蛋白质也可以用作具有抗菌活性的抗微生物蛋白。在多个转录变异体，其编码相同的蛋白质选择性剪接的结果。[通过的RefSeq，2014年11月提供]

OMIM数据库中对REG3A基因的介绍 Wikipedia数据库中对REG3A基因的介绍

REG3A基因的碱基序列：[NCBI]

REG3A基因的碱基突变：显示全部snp

rs2272108 rs2272109 rs2272110 rs7581353 rs7584199 rs7584436 rs7588571 rs7598318 rs7607786 rs10169162 rs12471852 rs35098845 rs55931447 rs56271358 rs56413330 rs72816655 rs72913296 rs74415661 rs74976628 rs76653007 rs76852394 rs77686105 rs77721643 rs77854311 rs78465303 rs80188986 rs112445847 rs112838106 rs112889078 rs112949187 rs113052539 rs113136571 rs113179245 rs113348522 rs113959793 rs114006977 rs114456659

rs116083930 rs137901701 rs138199548 rs138347548 rs138628628 rs139201953 rs139938567 rs140437330 rs140820070 rs141740162 rs141838256 rs142258321 rs142625281 rs142906305 rs143057391 rs143355005 rs143469095 rs145399597 rs145613581 rs145689287 rs146653158 rs146689461 rs147161306 rs149222950 rs149324194 rs149849110 rs150043684 rs150144136 rs150496065 rs150805284 rs151120041 rs181480668 rs182319666 rs183252208 rs183324465 rs183551507 rs183588096 rs184527901 rs184620715 rs185761973 rs186716101 rs187429978 rs187541059 rs187909920 rs188596266 rs188662804 rs189412012 rs189432841 rs189570492 rs190335034 rs190379872 rs192223344 rs192834431 rs192886235 rs199719324 rs199733463 rs199786695 rs199992892 rs200135428 rs200652760 rs201118015 rs201139260 rs201329432 rs201428369 rs202062830 rs202236751 rs368313335 rs369432431 rs370034417 rs370618564 rs370821567 rs370986858 rs371806510 rs372450124 rs372677110 rs372756064 rs373555863 rs374191223 rs375140321 rs376473212 rs376977811 rs377029307 rs377041576 rs377170918 rs528759526 rs528818605 rs530190418 rs530771794 rs530807030 rs531119713 rs531126939 rs533239357 rs533241635 rs534251797 rs534603651 rs534662016 rs535526679 rs536933780 rs537169817 rs538408283 rs538534548 rs538840781 rs538996670 rs539365141 rs539371601 rs540199253 rs540271676 rs541195784 rs542417204 rs542541454 rs543137414 rs543175598 rs543576857 rs544174610 rs544385326 rs544569659 rs544928626 rs545029936 rs545912270 rs546555301 rs547113093 rs547939249 rs548094279 rs548260649 rs548572259 rs548580132 rs548716106 rs550407979 rs550797299 rs550933837 rs550965564 rs552809220 rs552946330 rs553272882 rs554119036 rs554252929 rs554895913 rs555526789 rs555563988 rs556491033 rs556611891 rs556646764 rs557661938 rs557947907 rs558734956 rs560091517 rs560305433 rs560594249 rs560783950 rs560963480 rs561853007 rs561923597 rs562133331 rs562358530 rs563327404 rs564365018 rs565734557 rs566064093 rs566380503 rs566535446 rs566862747 rs567789807 rs567836472 rs567952259 rs568367404 rs568466219 rs569038111 rs570333977 rs570458867 rs571781122 rs572316355 rs572545678 rs572660893 rs572852123 rs573422152 rs573988391 rs574056135 rs574526028 rs575474282 rs575505948 rs576983078 rs577021460 rs577215516 rs578006392 rs578176885 rs745466115 rs745928990 rs746142667 rs746226853 rs746501690 rs746611738 rs746972535 rs747243184 rs747395684 rs747672522 rs747687128 rs747905959 rs747924690 rs748177286 rs748651336 rs749016320 rs749033640 rs749392830 rs749642414 rs749658818 rs749713335 rs750533462 rs750696512 rs751689325 rs752224662 rs752386140 rs752620292 rs752943154 rs753027521 rs753096835 rs753136032 rs753283504 rs753374073 rs753705415 rs753973300 rs754039912 rs754554463 rs754646366 rs754816439 rs755346076 rs755363230 rs755435645 rs755559938 rs755718299 rs756262382 rs756354351 rs756356041 rs756511614 rs757161884 rs757279625 rs757341912 rs757350010 rs757491659 rs757776608 rs758104356 rs758278763 rs758470629 rs758481517 rs758760547 rs758852073 rs758995504 rs759104417 rs759349290 rs759637207 rs759671401 rs760354285 rs760511635 rs760712859 rs760956845 rs761688072 rs761859740 rs762241190 rs762329480 rs762429049 rs762763582 rs762820898 rs763231004 rs763390886 rs764024027 rs764029952 rs764419758 rs764507577 rs764774499 rs764993153 rs765218597 rs765224350 rs765360947 rs765496540 rs765861996 rs766411434 rs766492988 rs766585040 rs766640942 rs766797789 rs767451070 rs767539542 rs767916040 rs768103588 rs768210659 rs768317231 rs768482119 rs768568662 rs768991146 rs769149724 rs769272898 rs769503696 rs769616623 rs770292081 rs770646728 rs770647182 rs770679183 rs770807563 rs771324295 rs771521067 rs771935417 rs772027617 rs772275781 rs772655688 rs772804368 rs773255584 rs773468294 rs773556279 rs773670636 rs774802444 rs774925348 rs775081635 rs775380448 rs775447106 rs775456518 rs775648232 rs775928429 rs776481835 rs776507596 rs777098727 rs778024360 rs778546234 rs778718482 rs779093650 rs779422711 rs779442791 rs779485360 rs779530381 rs779543410 rs780244740 rs780270292 rs780358188 rs780812802 rs780972303 rs781248357 rs781336129 rs781453219 rs781494401

REG3A基因在不同组织中的表达： [UniProt]

正向引物序列

正向引物Tm值

反向引物序列

反向引物Tm值

rank

GAGTCGCAGACACTATGCT

59

CTTGAACCTGAGACAGCAG

58

GGTTCAAGGTGAAGAACCC

58

AAACAAGGCATAGCAGTGG

58

AGTCGCAGACACTATGCTG

59

CTTGAACCTGAGACAGCAG

58

CAGGTTCAAGGTGAAGAACC

58

AAACAAGGCATAGCAGTGG

58

AGAGTCGCAGACACTATGC

59

AAAGCAGCATCCAAGATACAC

59

GGTTCAAGGTGAAGAACCC

58

AGACACCAGGTTTCCAGAG

59

尚未收录相关数据

REG3A基因（以及对应的蛋白质）的细胞分布位置：

[UniProt] [GenomeNet]

溶酶体
内涵体
细胞核
细胞质
液泡
细胞膜
细胞外基质
内质网
线粒体
高尔基体
细胞骨架

REG3A基因的本体（GO）信息：

GO库代码

对应的蛋白质

来源代码

GO:0005515

Q06141(UniProtKB)

IPI

GO:0005615

Q06141(UniProtKB)

TAS

GO:0005737

Q06141(UniProtKB)

TAS

GO:0006953

Q06141(UniProtKB)

IEA

GO:0007157

Q06141(UniProtKB)

TAS

GO:0007275

Q06141(UniProtKB)

TAS

GO:0008283

Q06141(UniProtKB)

TAS

GO:0010838

Q06141(UniProtKB)

ISS

GO:0030246

Q06141(UniProtKB)

IEA

GO:0045617

Q06141(UniProtKB)

ISS

GO:0090303

Q06141(UniProtKB)

ISS

序号	作用方式	资源库来源/分值	基因名称	基因名称

可能调控REG3A基因的相关microRNA：

hsa-miR-30a hsa-miR-30a* hsa-miR-30b hsa-miR-30b* hsa-miR-30c hsa-miR-30d hsa-miR-30d* hsa-miR-30e hsa-miR-30e*

通路基因列表

疾病名称

关系值

NofPmids

NofSnps

来源

疾病名称	关系值	NofPmids	NofSnps	来源
Diabetes Mellitus, Non-Insulin-Dependent	0.080814326	4	0	BeFree_RGD
Pancreatitis, Chronic	0.080542884	4	0	BeFree_RGD
Pneumonia	0.08	1	0	RGD
Seizures	0.08	1	0	RGD
Sciatic Neuropathy	0.08	1	0	RGD
Alcoholic Intoxication, Chronic	0.004734064	2	0	GAD
Liver carcinoma	0.002985861	11	0	BeFree
Liver Failure	0.00272435	1	0	LHGDN
Alzheimer's Disease	0.002367032	1	0	GAD
Bipolar Disorder	0.002367032	1	1	GAD
Malignant neoplasm of pancreas	0.001628651	6	0	BeFree
Colorectal Carcinoma	0.001357209	5	0	BeFree
Cystic Fibrosis	0.001357209	5	0	BeFree
Pancreatic carcinoma	0.001357209	5	0	BeFree
Malignant neoplasm of liver	0.001357209	5	0	BeFree
Acute pancreatitis	0.001085767	4	0	BeFree
Diabetes Mellitus	0.001085767	4	0	BeFree
Liver neoplasms	0.001085767	4	0	BeFree
Colorectal Cancer	0.001085767	4	0	BeFree
Malignant tumor of colon	0.000814326	3	0	BeFree
Diabetes	0.000814326	3	0	BeFree
Pyelonephritis	0.000814326	3	0	BeFree
Cervical Intraepithelial Neoplasia	0.000814326	3	0	BeFree
MRSA - Methicillin resistant Staphylococcus aureus infection	0.000814326	3	0	BeFree
Carcinogenesis	0.000814326	3	0	BeFree
Colon Carcinoma	0.000814326	3	0	BeFree
Adenoma	0.000542884	2	0	BeFree
Malignant tumor of cervix	0.000542884	2	0	BeFree
HIV Infections	0.000542884	2	0	BeFree
Obesity	0.000542884	2	0	BeFree
Pancreatic Diseases	0.000542884	2	0	BeFree
Pulmonary Alveolar Proteinosis	0.000542884	2	0	BeFree
Cervix carcinoma	0.000542884	2	0	BeFree
Autosomal dominant retinitis pigmentosa	0.000542884	2	0	BeFree
Acute pyelonephritis	0.000542884	2	0	BeFree
Malignant neoplasm of skin	0.000271442	1	0	BeFree
Cervical dysplasia	0.000271442	1	0	BeFree
Colorectal Neoplasms	0.000271442	1	0	BeFree
Exanthema	0.000271442	1	0	BeFree
Glioblastoma	0.000271442	1	0	BeFree
Heart failure	0.000271442	1	0	BeFree
Congestive heart failure	0.000271442	1	0	BeFree
leukemia	0.000271442	1	0	BeFree
Lipodystrophy	0.000271442	1	0	BeFree
melanoma	0.000271442	1	0	BeFree
Pancreatitis	0.000271442	1	0	BeFree
Pituitary Adenoma	0.000271442	1	0	BeFree
Pituitary Diseases	0.000271442	1	0	BeFree
Psoriasis	0.000271442	1	0	BeFree
Kidney Failure	0.000271442	1	0	BeFree
Varicocele	0.000271442	1	0	BeFree
Severe Combined Immunodeficiency	0.000271442	1	0	BeFree
Hepatoblastoma	0.000271442	1	0	BeFree
POLYDACTYLY, POSTAXIAL	0.000271442	1	0	BeFree
Hereditary pancreatitis	0.000271442	1	0	BeFree
Liver and Intrahepatic Biliary Tract Carcinoma	0.000271442	1	0	BeFree
Adenocarcinoma in Situ	0.000271442	1	0	BeFree
Human papilloma virus infection	0.000271442	1	0	BeFree
Pancreatitis, Alcoholic	0.000271442	1	0	BeFree
Recurrent tumor	0.000271442	1	0	BeFree
PANCREAS EXOCRINE	0.000271442	1	0	BeFree
Spots on skin	0.000271442	1	0	BeFree
Lymphoma, Diffuse	0.000271442	1	0	BeFree