P2RY1(purinergic receptor P2Y, G-protein coupled, 1)

基因简称(symbol)
    [HGNC]     [GeneCards]     [NCBI]
基因种类(locus group)
同源简称(alias symbol)
基因家族代码(gene_family_id)
    [HGNC]     [GenScript]
omim代码
entrez码
    [Vega]
vega基因码
ensembl基因码
    [Ensembl]
基因家族(gene family)
refseq数据库代号

更多...

基因种类(locus_type)
基因名称状态(status)
location_sortable
同源基因名称(alias name)
基因名称批准使用时间(date_approved_reserved)
基因简称更名时间(date_symbol_changed)
基因名称更名时间(date_name_changed)
更新时间(date_modified)
ucsc码
ena
ccds数据码
uniprot数据码
pubmed代码
mgd码
rgd码
生命科学数据库(lsdb)
更新时间(date modified)
cosmic
mirbase
基因曾用简称(prev symbol)
基因曾用名称(prev name)
homeodb
cosmic
snornabase
bioparadigms slc
orphanet
假基因信息(pseudogeneorg)
horde id
merops
imgt
iuphar
kznf基因类别
mamit-trnadb
cd
LncRNA数据库
酶代码
中间纤维数据库

收起

3q25.2
基因染色体位置图

The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor functions as a receptor for extracellular ATP and ADP. In platelets binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and probably to platelet aggregation. [provided by RefSeq, Jul 2008]

[中文简述(自动翻译):]  这个基因的产物属于家庭的G蛋白偶联受体。该家族具有不同的药理学选择性,重叠在某些情况下,对各种腺苷和尿苷核苷酸几个受体亚型。该受体的功能为细胞外的ATP和ADP受体。在血小板结合的ADP通过磷脂酶C,在血小板形状的改变,并且可能对血小板聚集的活化导致动员细胞内钙离子。 [由RefSeq的,2008年7月提供]

P2RY1基因的碱基序列:[NCBI]
P2RY1基因的碱基突变:           显示全部snp
rs701265       rs1063103       rs1065776       rs1371097       rs1371098       rs1439009       rs1439026       rs2290916       rs3755711       rs5853613       rs7624866       rs7643597       rs9289876       rs10513433       rs11300426       rs11302342       rs12497578       rs16864605       rs16864613       rs16864614       rs17451266       rs41302198       rs56959008       rs59389242       rs61115581       rs67012448       rs73020223       rs73020228       rs73020230       rs73869849       rs75362116       rs76467490       rs77399688       rs77419830       rs77598898       rs78011023       rs78296387      
rs78522095       rs79596928       rs111692602       rs112058950       rs112530526       rs112649148       rs112737385       rs112880081       rs112887671       rs113395101       rs113428864       rs113595262       rs114044905       rs114070051       rs114394060       rs114551311       rs114599885       rs114700678       rs114912106       rs115122522       rs115692369       rs115814854       rs115871709       rs116436882       rs116783706       rs118182811       rs137998036       rs138272761       rs138733577       rs139453601       rs139893077       rs140441973       rs140909048       rs141231258       rs141746817       rs142610068       rs142648808       rs143383110       rs143983830       rs144160018       rs144362278       rs144727670       rs145371596       rs145384016       rs145510034       rs145510307       rs145570287       rs146233649       rs146245030       rs146412401       rs147723456       rs148838375       rs149358318       rs149676622       rs150184282       rs150415535       rs150595710       rs180842900       rs181084467       rs181736680       rs181771259       rs182330509       rs183262118       rs183580909       rs183606838       rs183833270       rs184449773       rs184910582       rs184913427       rs185168732       rs186480982       rs187049553       rs187314513       rs187831936       rs188078644       rs188129141       rs188733683       rs189352335       rs189591594       rs189756957       rs189853996       rs190125912       rs190867678       rs191409160       rs191831836       rs192429952       rs199546439       rs200067411       rs200305170       rs200547630       rs200574590       rs200589001       rs201004942       rs201214968       rs201815187       rs201872213       rs202007411       rs202164364       rs367763943       rs368261510       rs368489230       rs369758925       rs370708485       rs371292098       rs371629721       rs371909412       rs372649672       rs373291127       rs373648445       rs374021448       rs374496347       rs375198144       rs375587095       rs375733063       rs376276469       rs377085239       rs527491763       rs527615842       rs528595421       rs528673675       rs528858297       rs529651786       rs530659631       rs531587156       rs531652999       rs533537464       rs533618428       rs533683001       rs533831447       rs535911838       rs535974488       rs536177789       rs537902414       rs537963932       rs538433966       rs539039131       rs540376862       rs540726715       rs540833417       rs542227727       rs542290810       rs542322157       rs542457320       rs542957191       rs543202874       rs543704025       rs544212292       rs544272151       rs544385813       rs544451106       rs544780022       rs545160756       rs545676193       rs545813575       rs545822377       rs546569299       rs547031074       rs547163939       rs547575475       rs547596754       rs548057754       rs548537862       rs548886325       rs550246188       rs550506762       rs550593615       rs551573250       rs552588312       rs552645645       rs552907168       rs553367379       rs553502512       rs553682144       rs553820768       rs554025465       rs554380837       rs554559339       rs554699077       rs554833534       rs555160580       rs555812164       rs556156967       rs556554870       rs556696415       rs558488751       rs558683540       rs558820777       rs558981817       rs559221891       rs559375082       rs559719971       rs560173252       rs560380905       rs560558475       rs561086047       rs561163836       rs561204415       rs562003042       rs562551992       rs562566140       rs562889985       rs563024968       rs563160382       rs563484134       rs563950005       rs564013034       rs564086997       rs564191272       rs564328604       rs564748189       rs564785614       rs565020267       rs565670939       rs566087939       rs566152258       rs566556102       rs567057639       rs567126484       rs567248586       rs568026906       rs568173712       rs568942014       rs568960784       rs569080051       rs569174200       rs569238597       rs569452797       rs570268169       rs570303400       rs570436082       rs571017174       rs571032166       rs572886552       rs573427023       rs573454853       rs573512220       rs574361272       rs574843681       rs574911651       rs575422778       rs575558376       rs576492440       rs576637900       rs577237190       rs577304142       rs577890837       rs745322567       rs745510542       rs745892758       rs746345449       rs746535957       rs746655556       rs746918384       rs747027616       rs748097565       rs748105517       rs748290743       rs748459639       rs748730502       rs749790489       rs750665122       rs751962514       rs752051086       rs752205013       rs752295011       rs752467051       rs752732365       rs753534893       rs753589391       rs753615988       rs753619182       rs754007864       rs754452961       rs754613341       rs754801373       rs755529820       rs755787131       rs755868115       rs756222432       rs756754346       rs757057757       rs757144775       rs757232502       rs757564785       rs758295677       rs758599193       rs758771172       rs758787142       rs759185351       rs759251298       rs759555598       rs759577680       rs759773087       rs759907754       rs759997738       rs760274592       rs760860385       rs760951934       rs761142991       rs761210208       rs761337293       rs761404476       rs761994089       rs762164259       rs762472227       rs762563403       rs762673615       rs763198360       rs763314388       rs763623919       rs763681322       rs764055752       rs764537407       rs764733137       rs765090520       rs765390536       rs765483196       rs765965065       rs766253716       rs766534183       rs766553956       rs766711408       rs766799328       rs766915687       rs767106575       rs767315677       rs767594960       rs767663559       rs767718507       rs767844019       rs768092598       rs768238255       rs768662077       rs768811902       rs768901936       rs769145376       rs769335807       rs770279634       rs770369374       rs770513134       rs770603063       rs771382074       rs771419503       rs771571827       rs771661930       rs771986262       rs772467910       rs772650351       rs772918044       rs772947210       rs773107019       rs773771939       rs773862077       rs773997926       rs774039860       rs774252097       rs774343098       rs775481559       rs775571336       rs775577001       rs775765074       rs775959369       rs776251126       rs776798861       rs776845491       rs777279402       rs777298519       rs777590180       rs777701216       rs777781177       rs778251623       rs778362503       rs778842678       rs779121419       rs779296105       rs779299723       rs779398688       rs779494125       rs779961773       rs780073537       rs780204035       rs780556674       rs780725124       rs780823895       rs780911272       rs781198259       rs781219547       rs781310294      

P2RY1基因在不同组织中的表达:    [UniProt]

基因在不同组织中的表达图
正向引物序列
正向引物Tm值
反向引物序列
反向引物Tm值
rank
CAAGAGTGAAGACATGACCC
58
GCTTGTATCTCCATTCTGCT
57
CAATCCAAGAGTGAAGACATGAC
59
TATCTCCATTCTGCTTGAACTC
58
AATCCAAGAGTGAAGACATGAC
58
GTATCTCCATTCTGCTTGAACTC
59
      尚未收录相关数据

P2RY1基因(以及对应的蛋白质)的细胞分布位置:

[UniProt]     [GenomeNet]

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • 溶酶体
  • 内涵体
  • 细胞核
  • 细胞质
  • 液泡
  • 细胞膜
  • 细胞外基质
  • 内质网
  • 线粒体
  • 高尔基体
  • 细胞骨架

P2RY1基因的本体(GO)信息:

GO库代码
对应的蛋白质
来源代码
GO:0001934
P47900(UniProtKB)
ISS
GO:0001973
P47900(UniProtKB)
IEA
GO:0004872
P47900(UniProtKB)
TAS
GO:0005515
P47900(UniProtKB)
IPI
GO:0005524
P47900(UniProtKB)
IEA
GO:0005739
P47900(UniProtKB)
IEA
GO:0005829
P47900(UniProtKB)
IEA
GO:0005886
P47900(UniProtKB)
ISS
GO:0005886
P47900(UniProtKB)
TAS
GO:0005886
P47900(UniProtKB)
TAS
GO:0005886
P47900(UniProtKB)
TAS
GO:0005886
P47900(UniProtKB)
TAS
GO:0005886
P47900(UniProtKB)
TAS
GO:0005886
P47900(UniProtKB)
TAS
GO:0005887
P47900(UniProtKB)
TAS
GO:0007166
P47900(UniProtKB)
TAS
GO:0007186
P47900(UniProtKB)
ISS
GO:0007193
P47900(UniProtKB)
IEA
GO:0007200
P47900(UniProtKB)
IEA
GO:0007204
P47900(UniProtKB)
ISS
GO:0007568
P47900(UniProtKB)
IEA
GO:0008347
P47900(UniProtKB)
IEA
GO:0009612
P47900(UniProtKB)
IEA
GO:0009986
P47900(UniProtKB)
IDA
GO:0010469
P47900(UniProtKB)
IEA
GO:0010700
P47900(UniProtKB)
IEA
GO:0016323
P47900(UniProtKB)
IEA
GO:0016324
P47900(UniProtKB)
IEA
GO:0019233
P47900(UniProtKB)
IEA
GO:0023019
P47900(UniProtKB)
ISS
GO:0030168
P47900(UniProtKB)
IEA
GO:0030425
P47900(UniProtKB)
ISS
GO:0031686
P47900(UniProtKB)
IEA
GO:0032962
P47900(UniProtKB)
IEA
GO:0035589
P47900(UniProtKB)
IEA
GO:0042312
P47900(UniProtKB)
IEA
GO:0042755
P47900(UniProtKB)
IEA
GO:0043270
P47900(UniProtKB)
IEA
GO:0043531
P47900(UniProtKB)
IEA
GO:0044297
P47900(UniProtKB)
ISS
GO:0045028
P47900(UniProtKB)
ISS
GO:0045031
P47900(UniProtKB)
ISS
GO:0045032
P47900(UniProtKB)
IEA
GO:0045211
P47900(UniProtKB)
ISS
GO:0045944
P47900(UniProtKB)
IEA
GO:0046887
P47900(UniProtKB)
IEA
GO:0046982
P47900(UniProtKB)
IEA
GO:0051100
P47900(UniProtKB)
IEA
GO:0060406
P47900(UniProtKB)
IEA
GO:0070374
P47900(UniProtKB)
ISS
GO:0070848
P47900(UniProtKB)
IEA
GO:0071407
P47900(UniProtKB)
IEA
GO:0072659
P47900(UniProtKB)
ISS
GO:0090075
P47900(UniProtKB)
IEA
GO:0097110
P47900(UniProtKB)
ISS
GO:0097481
P47900(UniProtKB)
ISS
基因与其他基因之间的相互作用关系图
序号 作用方式 资源库来源/分值 基因名称 基因名称

可能调控P2RY1基因的相关microRNA:     


通路基因列表
疾病名称 关系值 NofPmids NofSnps 来源
疾病名称 关系值 NofPmids NofSnps 来源
Thrombosis 0.12 1 0 CTD_human
Erectile dysfunction 0.08 1 0 RGD
Skin Neoplasms 0.00272435 1 0 LHGDN
Atherosclerosis 0.002367032 1 0 GAD
HIV Infections 0.002367032 1 0 GAD
Chronic Lymphocytic Leukemia 0.002367032 1 2 GAD
ASPIRIN RESISTANCE 0.002367032 1 0 GAD
Lupus Erythematosus, Systemic 0.000814326 3 0 BeFree
Amyotrophic Lateral Sclerosis 0.000542884 2 0 BeFree
Astrocytoma 0.000542884 2 0 BeFree
Bipolar Disorder 0.000542884 2 0 BeFree
Coronary Arteriosclerosis 0.000542884 2 0 BeFree
Coronary heart disease 0.000542884 2 0 BeFree
Glioma 0.000542884 2 0 BeFree
Malignant neoplasm of prostate 0.000542884 2 0 BeFree
Prostate carcinoma 0.000542884 2 0 BeFree
Coronary Artery Disease 0.000542884 2 0 BeFree
Alzheimer's Disease 0.000271442 1 0 BeFree
Blood Coagulation Disorders 0.000271442 1 0 BeFree
Chlamydia Infections 0.000271442 1 0 BeFree
Diabetes 0.000271442 1 0 BeFree
Diabetes Mellitus 0.000271442 1 0 BeFree
Fatigue 0.000271442 1 0 BeFree
Ischemia 0.000271442 1 0 BeFree
Myeloid Leukemia 0.000271442 1 0 BeFree
Schizophrenia 0.000271442 1 0 BeFree
Septicemia 0.000271442 1 0 BeFree
Sudden infant death syndrome 0.000271442 1 0 BeFree
Toxoplasmosis 0.000271442 1 0 BeFree
Tuberculosis, Pulmonary 0.000271442 1 0 BeFree
Diffuse Large B-Cell Lymphoma 0.000271442 1 0 BeFree
Squamous cell carcinoma of lung 0.000271442 1 0 BeFree
Retinal ischemia 0.000271442 1 0 BeFree
Tumor Progression 0.000271442 1 0 BeFree
Sepsis 0.000271442 1 0 BeFree
Mood Disorders 0.000271442 1 0 BeFree
Intraocular pressure disorder 0.000271442 1 0 BeFree
Carcinogenesis 0.000271442 1 0 BeFree
Thrombocytosis 0.000271442 1 0 BeFree
Mammary Neoplasms 0.000271442 1 0 BeFree
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