LPA(lipoprotein, Lp(a)) 转至新版数据库

基因基本信息

基因基本信息

基因简称(symbol)
    [HGNC]     [GeneCards]     [NCBI]
基因种类(locus group)
同源简称(alias symbol)
基因家族代码(gene_family_id)
    [HGNC]     [GenScript]
omim代码
entrez码
    [Vega]
vega基因码
ensembl基因码
    [Ensembl]
基因家族(gene family)
refseq数据库代号

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基因种类(locus_type)
基因名称状态(status)
location_sortable
同源基因名称(alias name)
基因名称批准使用时间(date_approved_reserved)
基因简称更名时间(date_symbol_changed)
基因名称更名时间(date_name_changed)
更新时间(date_modified)
ucsc码
ena
ccds数据码
uniprot数据码
pubmed代码
mgd码
rgd码
生命科学数据库(lsdb)
更新时间(date modified)
cosmic
mirbase
基因曾用简称(prev symbol)
基因曾用名称(prev name)
homeodb
cosmic
snornabase
bioparadigms slc
orphanet
假基因信息(pseudogeneorg)
horde id
merops
imgt
iuphar
kznf基因类别
mamit-trnadb
cd
LncRNA数据库
酶代码
中间纤维数据库

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基因染色体位置

基因染色体位置

6q25-q26
基因染色体位置图

基因简述

基因简述

The protein encoded by this gene is a serine proteinase that inhibits the activity of tissue-type plasminogen activator I. The encoded protein constitutes a substantial portion of lipoprotein(a) and is proteolytically cleaved, resulting in fragments that attach to atherosclerotic lesions and promote thrombogenesis. Elevated plasma levels of this protein are linked to atherosclerosis. Depending on the individual, the encoded protein contains 2-43 copies of kringle-type domains. The allele represented here contains 15 copies of the kringle-type repeats and corresponds to that found in the reference genome sequence. [provided by RefSeq, Dec 2009]

[中文简述(自动翻译):]  由该基因编码的蛋白质是一个丝氨酸蛋白酶抑制组织型纤溶酶原激活物I的活性的编码的蛋白质构成脂蛋白（a）的主要部分，并且蛋白水解切割，产生附加到动脉粥样硬化的片段病变和促进血栓形成。这种蛋白质的升高的血浆水平与动脉粥样硬化。取决于个体，编码的蛋白质含有三环式结构域的2-43份。这里表示的等位基因包含三环式重复15份，并对应于，在参照基因组序列中发现。 [由RefSeq的，2009年12月提供]

OMIM数据库中对LPA基因的介绍     Wikipedia数据库中对LPA基因的介绍

基因序列

基因序列

LPA基因的碱基序列：[NCBI]

基因突变

基因突变

LPA基因的碱基突变：           显示全部snp
rs2834       rs783148       rs783149       rs934266       rs1321195       rs1321196       rs1367209       rs1367210       rs1367211       rs1406889       rs1569933       rs1623955       rs1652507       rs1740428       rs1800589       rs1800769       rs1801693       rs1830522       rs1848847       rs1848848       rs1853021       rs1876989       rs1950563       rs1950564       rs2089736       rs2092931       rs2144726       rs2315129       rs2872764       rs2983236       rs3011437       rs3124784       rs3124785       rs3127596       rs3798220       rs3798221       rs3798223      
rs3839350       rs3883930       rs3902910       rs3927200       rs4073498       rs4708871       rs4708873       rs4708876       rs4709450       rs4709451       rs4709452       rs4709455       rs6415084       rs6415085       rs6455688       rs6455689       rs6455691       rs6455692       rs6455693       rs6455694       rs6455695       rs6455696       rs6455697       rs6899379       rs6902102       rs6903340       rs6903649       rs6904684       rs6905073       rs6905422       rs6905823       rs6906412       rs6906446       rs6907156       rs6910635       rs6911202       rs6913833       rs6917128       rs6919083       rs6919346       rs6919497       rs6920765       rs6921516       rs6921912       rs6922216       rs6922557       rs6923877       rs6923917       rs6926201       rs6926458       rs6926896       rs6927129       rs6929299       rs6930342       rs6930542       rs6932014       rs6933576       rs6937353       rs6937879       rs6938647       rs6939089       rs6940254       rs6940297       rs6941715       rs7449650       rs7449940       rs7450109       rs7450261       rs7450279       rs7450411       rs7450719       rs7451762       rs7451767       rs7453635       rs7453826       rs7453899       rs7453965       rs7454595       rs7454656       rs7454962       rs7739883       rs7743213       rs7743535       rs7745744       rs7746273       rs7746421       rs7746435       rs7750229       rs7750595       rs7750767       rs7752408       rs7752726       rs7752727       rs7754522       rs7754526       rs7755463       rs7755665       rs7756317       rs7758127       rs7759314       rs7759633       rs7760585       rs7761293       rs7761377       rs7765684       rs7765781       rs7765803       rs7766300       rs7767084       rs7767342       rs7769523       rs7769720       rs7770628       rs7770685       rs7771129       rs7771801       rs7775600       rs7775704       rs9295130       rs9346820       rs9346821       rs9346824       rs9346825       rs9346826       rs9346833       rs9347412       rs9347414       rs9347418       rs9347419       rs9347422       rs9347424       rs9347428       rs9347431       rs9347433       rs9347434       rs9347436       rs9347437       rs9347438       rs9355291       rs9355295       rs9355296       rs9355297       rs9355299       rs9355303       rs9355307       rs9355808       rs9355813       rs9355814       rs9355815       rs9355816       rs9355817       rs9364559       rs9364561       rs9364562       rs9364563       rs9364564       rs9364566       rs9364567       rs9365169       rs9365171       rs9365172       rs9365173       rs9365174       rs9365177       rs9365178       rs9365179       rs9365187       rs9365189       rs9365196       rs9365200       rs9365201       rs9456547       rs9456548       rs9456549       rs9456550       rs9456551       rs9456552       rs9456554       rs9456566       rs9456567       rs9456573       rs9457933       rs9457934       rs9457935       rs9457936       rs9457937       rs9457938       rs9457939       rs9457940       rs9457941       rs9457943       rs9457945       rs9457946       rs9457947       rs9457948       rs9457949       rs9457950       rs9457951       rs9457952       rs9457953       rs9457954       rs9457961       rs9457986       rs9457988       rs10046251       rs10046252       rs10046272       rs10081128       rs10085279       rs10455872       rs10526739       rs10548212       rs10552460       rs10573335       rs10755578       rs10945675       rs10945677       rs10945682       rs10945683       rs11751605       rs11752803       rs11759364       rs11961303       rs11965048       rs11966156       rs11969491       rs11970415       rs12175867       rs12190825       rs12194138       rs12205797       rs12207195       rs12208731       rs12210186       rs12212507       rs12525447       rs12526465       rs12526589       rs12665784       rs13192132       rs13193251       rs13194662       rs13198987       rs13202636       rs13306529       rs13306530       rs13306531       rs17557261       rs34448740       rs34498812       rs34600300       rs34620808       rs34747443       rs35122050       rs35189165       rs35220367       rs35358746       rs35499210       rs35600881       rs36115561       rs41259144       rs41264288       rs41264290       rs41264292       rs41264294       rs41264296       rs41264298       rs41264300       rs41264302       rs41264304       rs41264306       rs41264308       rs41264310       rs41264312       rs41264314       rs41264316       rs41264318       rs41264320       rs41264322       rs41264324       rs41264326       rs41264328       rs41264330       rs41264332       rs41264334       rs41264336       rs41264338       rs41264340       rs41264342       rs41264844       rs41264846       rs41264848       rs41264850       rs41264852       rs41264854       rs41264856       rs41264858       rs41264860       rs41264862       rs41264864       rs41265922       rs41265924       rs41265926       rs41265928       rs41265930       rs41265934       rs41265936       rs41265938       rs41265940       rs41265942       rs41266344       rs41266346       rs41266348       rs41266350       rs41266352       rs41266354       rs41266356       rs41266358       rs41266360       rs41266362       rs41266364       rs41266365       rs41266367       rs41266369       rs41266371       rs41266373       rs41266375       rs41266377       rs41266379       rs41266381       rs41266383       rs41266385       rs41266387       rs41267807       rs41267809       rs41267811       rs41267813       rs41267815       rs41267817       rs41267819       rs41267829       rs41267831       rs41269131       rs41269133       rs41269135       rs41269136       rs41269138       rs41269140       rs41269142       rs41269844       rs41269846       rs41269848       rs41269850       rs41269852       rs41269854       rs41269856       rs41269858       rs41269860       rs41269862       rs41269864       rs41269866       rs41269868       rs41269870       rs41269872       rs41269874       rs41269876       rs41269878       rs41269880       rs41269882       rs41269884       rs41269886       rs41269888       rs41269890       rs41269892       rs41269894       rs41269896       rs41270976       rs41270978       rs41270980       rs41270982       rs41270984       rs41270986       rs41270988       rs41270990       rs41270992       rs41270994       rs41270996       rs41270998       rs41271000       rs41271002       rs41271004       rs41271006       rs41271008       rs41271010       rs41271012       rs41271014       rs41271016       rs41271018       rs41271020       rs41271022       rs41271024       rs41271028       rs41271030       rs41271032       rs41271034       rs41271036       rs41271038       rs41271040       rs41271042       rs41272044       rs41272046       rs41272048       rs41272050       rs41272052       rs41272054       rs41272056       rs41272058       rs41272060       rs41272062       rs41272064       rs41272066       rs41272068       rs41272070       rs41272072       rs41272074       rs41272076       rs41272078       rs41272080       rs41272082       rs41272084       rs41272086       rs41272088       rs41272090       rs41272092       rs41272094       rs41272096       rs41272098       rs41272100       rs41272102       rs41272104       rs41272106       rs41272108       rs41272110       rs41272112       rs41272114       rs41272116       rs41272118       rs41272120       rs41272122       rs41272124       rs41272126       rs41272128       rs41272130       rs55699603       rs55730499       rs55808219       rs55913921       rs56199881       rs56393506       rs56791859       rs56850029       rs57732497       rs57976993       rs58013227       rs58574154       rs58787790       rs59040870       rs59112254       rs59345315       rs59566810       rs59653355       rs59760174       rs60321597       rs60700834       rs60742360       rs61120739       rs61213360       rs62159739       rs62439760       rs62441702       rs62441703       rs62441715       rs62441716       rs62441718       rs62441743       rs62441895       rs62441897       rs62441899       rs62441900       rs62441901       rs62441902       rs62441903       rs62441905       rs62441908       rs62441936       rs62442778       rs62442779       rs62442784       rs62621433       rs67979615       rs71033583       rs71033585       rs71033586       rs71228486       rs71542980       rs71542981       rs71558050       rs71565773       rs72314471       rs73012273       rs73012278       rs73012297       rs73012302       rs73014164       rs73014179       rs73594859       rs73594862       rs73594865       rs73594866       rs73594872       rs73594879       rs73594888       rs73594892       rs73594901       rs73596816       rs73596849       rs73596859       rs73782408       rs73782415       rs73784275       rs73784276       rs73784277       rs73784278       rs73784279       rs73784280       rs73784281       rs73784283       rs73784285       rs73784287       rs73784288       rs73784289       rs73784292       rs73784294       rs73784295       rs73784299       rs73784300       rs73784302       rs73785605       rs73785607       rs73785611       rs73785613       rs74190405       rs74208085       rs74334585       rs74398319       rs74399546       rs74402353       rs74404410       rs74422221       rs74484308       rs74490667       rs74511593       rs74536224       rs74598183       rs74617384       rs74620584       rs74655412       rs74734070       rs74811234       rs74865159       rs74877153       rs74965889       rs74986501       rs75016826       rs75055004       rs75111619       rs75188747       rs75234242       rs75274517       rs75321363       rs75385813       rs75424478       rs75482932       rs75515622       rs75573224       rs75692336       rs75694417       rs75695638       rs75839996       rs75975753       rs76000021       rs76027460       rs76029168       rs76062330       rs76116530       rs76144756       rs76185538       rs76211344       rs76214705       rs76249505       rs76285645       rs76404150       rs76523470       rs76532515       rs76583114       rs76602267       rs76640890       rs76735376       rs76781348       rs76852953       rs76856247       rs76896080       rs76924353       rs77009508       rs77127985       rs77130809       rs77182492       rs77186616       rs77193130       rs77202442       rs77204888       rs77312687       rs77318095       rs77337569       rs77348928       rs77372228       rs77408232       rs77460862       rs77564834       rs77638119       rs77644736       rs77646327       rs77651956       rs77753059       rs77780512       rs77992356       rs78115010       rs78199196       rs78244027       rs78267170       rs78325178       rs78340775       rs78347018       rs78350869       rs78363782       rs78421331       rs78432041       rs78588489       rs78634584       rs78639363       rs78691946       rs78733124       rs78815698       rs78822335       rs78842012       rs78893353       rs78953058       rs78954194       rs79018195       rs79035557       rs79060090       rs79061691       rs79103498       rs79186181       rs79246098       rs79263878       rs79313042       rs79319956       rs79327486       rs79417895       rs79462385       rs79563112       rs79573995       rs79575867       rs79653994       rs79776968       rs79975507       rs80016932       rs80019575       rs80106498       rs80109731       rs80113245       rs80145669       rs80147224       rs80187955       rs80220946       rs80297873       rs80298080       rs80341857       rs111107838       rs111162624       rs111210748       rs111210749       rs111210750       rs111228046       rs111278129       rs111327256       rs111332320       rs111355374       rs111366150       rs111398110       rs111402863       rs111425455       rs111432018       rs111435452       rs111438313       rs111444797       rs111453606       rs111585316       rs111611345       rs111615322       rs111623026       rs111651183       rs111654599       rs111657849       rs111672621       rs111674165       rs111681430       rs111686223       rs111696723       rs111771659       rs111859161       rs111883605       rs111921046       rs111935319       rs111937435       rs111939969       rs112001850       rs112018299       rs112021077       rs112038494       rs112048147       rs112061390       rs112092923       rs112098335       rs112113673       rs112116241       rs112136128       rs112152453       rs112171168       rs112191363       rs112230474       rs112261863       rs112267308       rs112334930       rs112416174       rs112444533       rs112462697       rs112481253       rs112492734       rs112515320       rs112518707       rs112650738       rs112658628       rs112674811       rs112683303       rs112728285       rs112781702       rs112801858       rs112820619       rs112821226       rs112842440       rs112870860       rs112875476       rs112877245       rs112928234       rs112936231       rs112939444       rs112985230       rs113007091       rs113007272       rs113011905       rs113020022       rs113024957       rs113030881       rs113108099       rs113217158       rs113236095       rs113267981       rs113280576       rs113291096       rs113291404       rs113305865       rs113336203       rs113359915       rs113428210       rs113431950       rs113444323       rs113461388       rs113486975       rs113494184       rs113509229       rs113514170       rs113528624       rs113544935       rs113556799       rs113572208       rs113578418       rs113585105       rs113606054       rs113673715       rs113694357       rs113708485       rs113727842       rs113739953       rs113740114       rs113757744       rs113758051       rs113759838       rs113798069       rs113829652       rs113881257       rs113946241       rs113959784       rs113968060       rs114018303       rs114020539       rs114064806       rs114159184       rs114163016       rs114210880       rs114259015       rs114261511       rs114300307       rs114306707       rs114322360       rs114326577       rs114394812       rs114441771       rs114481473       rs114568515       rs114573027       rs114591665       rs114660152       rs114694418       rs114766146       rs114814578       rs114831934       rs114909802       rs114914749       rs114967991       rs115013883       rs115018991       rs115038870       rs115084208       rs115227831       rs115280015       rs115281078       rs115283026       rs115365875       rs115366121       rs115405773       rs115542836       rs115555831       rs115557600       rs115600662       rs115625992       rs115634866       rs115686815       rs115689904       rs115704782       rs115726057       rs115739169       rs115740213       rs115758656       rs115770762       rs115814410       rs115848955       rs115852011       rs115924742       rs115952177       rs115992524       rs116039216       rs116068088       rs116089584       rs116095335       rs116109016       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rs750090409       rs750127931       rs750180954       rs750190640       rs750194141       rs750237739       rs750270659       rs750274655       rs750302414       rs750325646       rs750360599       rs750367322       rs750406053       rs750408547       rs750413087       rs750438907       rs750455624       rs750621364       rs750682358       rs750685328       rs750723354       rs750804684       rs750817573       rs750818276       rs750838747       rs750870384       rs750911873       rs750926596       rs750930392       rs751059384       rs751098304       rs751099465       rs751108386       rs751125113       rs751136142       rs751147524       rs751170093       rs751209890       rs751211158       rs751233482       rs751267533       rs751378440       rs751399113       rs751426091       rs751489209       rs751514001       rs751525672       rs751529255       rs751547669       rs751568657       rs751658100       rs751715490       rs751717117       rs751745914       rs751823130       rs751830202       rs751841836       rs751881662       rs751971323       rs751993714       rs752045505       rs752058838       rs752135419       rs752139084       rs752170747       rs752189291       rs752226840       rs752283952       rs752311479       rs752316760       rs752392813       rs752404735       rs752415998       rs752450568       rs752503682       rs752521694       rs752526227       rs752563280       rs752667995       rs752669457       rs752685835       rs752721130       rs752734941       rs752757407       rs752793579       rs752815249       rs752907138       rs752951937       rs752997018       rs753018050       rs753053304       rs753096833       rs753102310       rs753144966       rs753180293       rs753215028       rs753227907       rs753250920       rs753280060       rs753321675       rs753368052       rs753371576       rs753423591       rs753427138       rs753460542       rs753517059       rs753560847       rs753610068       rs753633188       rs753674698       rs753698964       rs753758952       rs753810486       rs753812356       rs753839702       rs753857966       rs753860396       rs753865531       rs753952578       rs754020853       rs754047895       rs754129341       rs754157911       rs754279370       rs754279604       rs754330108       rs754339898       rs754341114       rs754367400       rs754369095       rs754417042       rs754417184       rs754625463       rs754711266       rs754714588       rs754721328       rs754788844       rs754796697       rs754829157       rs754831117       rs754831253       rs754840017       rs754855527       rs754876758       rs754897471       rs754916925       rs754922180       rs754984307       rs755027032       rs755063764       rs755195697       rs755236015       rs755292726       rs755297866       rs755316629       rs755392689       rs755418816       rs755470698       rs755484600       rs755513978       rs755560331       rs755563925       rs755575417       rs755587107       rs755588775       rs755720720       rs755767558       rs755788271       rs755876095       rs755904089       rs755973519       rs755991783       rs755995725       rs756005880       rs756035439       rs756048207       rs756065579       rs756156477       rs756186725       rs756196821       rs756252809       rs756286615       rs756292632       rs756329124       rs756366151       rs756380539       rs756443521       rs756487300       rs756542621       rs756570589       rs756575427       rs756618647       rs756630466       rs756630781       rs756663947       rs756666809       rs756718229       rs756718571       rs756749738       rs756764319       rs756764320       rs756824494       rs756852405       rs756905256       rs756944525       rs756954393       rs756971350       rs757041326       rs757049699       rs757072183       rs757112211       rs757113256       rs757188741       rs757199474       rs757242594       rs757296266       rs757344451       rs757352277       rs757408026       rs757455105       rs757468292       rs757497992       rs757541794       rs757574674       rs757595573       rs757624375       rs757642340       rs757662668       rs757709383       rs757743356       rs757763606       rs757801121       rs757827567       rs757830711       rs757921434       rs757992874       rs758000323       rs758003120       rs758009259       rs758029376       rs758093097       rs758104639       rs758116527       rs758202909       rs758209955       rs758243634       rs758269477       rs758288924       rs758300066       rs758309878       rs758317277       rs758336014       rs758337443       rs758361188       rs758381610       rs758400355       rs758408377       rs758433445       rs758495741       rs758496213       rs758509383       rs758521868       rs758555815       rs758596677       rs758644211       rs758688036       rs758742474       rs758789292       rs758893863       rs758990812       rs759078765       rs759100515       rs759116039       rs759164714       rs759203171       rs759225410       rs759236772       rs759246724       rs759257281       rs759342984       rs759355074       rs759383387       rs759479249       rs759499133       rs759511353       rs759541475       rs759552411       rs759571414       rs759584520       rs759599573       rs759697610       rs759731842       rs759753353       rs759758713       rs759786688       rs759821833       rs759840734       rs759880143       rs759967629       rs759978197       rs759979184       rs760005750       rs760055523       rs760090340       rs760163996       rs760239476       rs760264276       rs760289338       rs760296024       rs760296043       rs760313861       rs760356439       rs760391317       rs760452261       rs760461740       rs760463467       rs760479592       rs760501779       rs760611402       rs760658658       rs760667340       rs760679789       rs760705738       rs760728608       rs760748892       rs760752632       rs760859234       rs760908818       rs761015939       rs761109781       rs761118079       rs761134280       rs761151532       rs761153549       rs761191628       rs761239764       rs761329449       rs761329964       rs761345632       rs761351824       rs761418281       rs761421000       rs761476925       rs761596691       rs761597778       rs761609176       rs761614499       rs761686158       rs761689365       rs761691644       rs761704414       rs761853859       rs761873886       rs761904347       rs761990517       rs762092223       rs762145871       rs762177089       rs762182030       rs762183494       rs762221347       rs762249934       rs762251948       rs762273541       rs762337953       rs762351463       rs762356716       rs762386030       rs762448806       rs762524065       rs762542305       rs762570044       rs762661316       rs762661856       rs762669456       rs762748478       rs762751349       rs762751922       rs762838420       rs762900542       rs762930505       rs762956008       rs762963067       rs762988429       rs763012249       rs763023830       rs763044981       rs763148795       rs763173798       rs763222955       rs763227955       rs763303641       rs763307506       rs763313272       rs763369743       rs763378063       rs763395489       rs763417427       rs763435449       rs763465616       rs763492052       rs763516101       rs763560735       rs763564952       rs763566344       rs763605520       rs763610034       rs763635835       rs763700880       rs763721114       rs763721676       rs763781934       rs763814461       rs763818436       rs763820546       rs763838535       rs763925421       rs763945626       rs763981654       rs764008333       rs764024964       rs764033275       rs764038715       rs764041407       rs764069644       rs764089716       rs764114914       rs764153275       rs764191223       rs764191464       rs764211344       rs764213160       rs764218090       rs764296652       rs764320447       rs764341997       rs764378147       rs764408441       rs764431222       rs764432205       rs764432277       rs764468243       rs764520726       rs764529954       rs764584249       rs764610863       rs764672788       rs764688452       rs764688579       rs764693520       rs764778406       rs764783751       rs764852306       rs764862615       rs764894583       rs765006148       rs765006225       rs765076734       rs765105273       rs765144948       rs765264997       rs765298455       rs765303561       rs765314362       rs765336864       rs765352339       rs765360409       rs765386320       rs765393951       rs765479327       rs765540048       rs765582741       rs765658131       rs765666237       rs765700553       rs765746657       rs765765045       rs765779118       rs765839691       rs765841245       rs765875612       rs765927115       rs765927630       rs765929717       rs765984084       rs766023772       rs766035711       rs766070403       rs766091375       rs766143004       rs766181498       rs766239484       rs766244684       rs766252127       rs766323820       rs766352738       rs766412953       rs766416190       rs766420598       rs766451206       rs766540727       rs766542286       rs766676715       rs766717857       rs766732391       rs766811168       rs766884402       rs766888732       rs766897670       rs766900075       rs766906240       rs766976846       rs766996232       rs766996320       rs767075353       rs767083976       rs767117513       rs767165360       rs767184549       rs767207085       rs767234041       rs767240806       rs767271271       rs767378787       rs767384369       rs767471776       rs767549740       rs767564396       rs767574694       rs767633287       rs767636813       rs767641571       rs767721027       rs767785181       rs767808908       rs767809248       rs767877551       rs767879638       rs767904792       rs767906902       rs767951237       rs768041054       rs768072721       rs768127138       rs768132099       rs768183255       rs768224048       rs768235276       rs768325422       rs768388318       rs768415298       rs768422865       rs768435856       rs768477904       rs768478207       rs768497880       rs768559622       rs768779893       rs768808174       rs768833450       rs768841851       rs768886980       rs768922928       rs768979049       rs768985379       rs768994342       rs769054975       rs769068995       rs769084235       rs769096266       rs769124602       rs769200592       rs769211557       rs769212651       rs769282211       rs769308790       rs769324261       rs769327775       rs769350529       rs769453068       rs769482476       rs769499531       rs769502232       rs769538910       rs769567742       rs769620286       rs769627355       rs769645630       rs769648601       rs769648669       rs769706821       rs769737517       rs769877425       rs769952378       rs769969785       rs769987748       rs770035632       rs770060918       rs770135818       rs770156919       rs770166561       rs770167296       rs770212466       rs770223736       rs770246075       rs770254581       rs770263408       rs770276913       rs770294385       rs770351354       rs770353419       rs770360852       rs770419679       rs770424355       rs770505140       rs770547132       rs770552244       rs770568866       rs770600211       rs770603201       rs770611055       rs770633079       rs770658328       rs770691046       rs770697709       rs770717883       rs770730458       rs770776326       rs770784395       rs770821589       rs770898075       rs770911603       rs770911775       rs770928237       rs770935162       rs770999731       rs771023670       rs771057576       rs771127354       rs771174147       rs771218902       rs771266499       rs771320392       rs771367882       rs771372205       rs771406249       rs771495182       rs771569082       rs771579859       rs771587019       rs771607025       rs771609508       rs771656069       rs771701529       rs771704976       rs771731681       rs771744742       rs771773768       rs771794267       rs771836727       rs771845458       rs771863444       rs771927645       rs771935615       rs771970451       rs772001636       rs772071086       rs772137514       rs772241076       rs772310605       rs772361102       rs772361721       rs772373168       rs772405081       rs772415624       rs772433112       rs772483615       rs772492631       rs772497912       rs772588686       rs772636245       rs772656794       rs772747145       rs772798966       rs772825976       rs772826531       rs773010957       rs773018558       rs773026456       rs773045378       rs773053530       rs773112471       rs773135129       rs773141063       rs773216354       rs773276900       rs773299288       rs773306459       rs773309336       rs773326776       rs773327709       rs773387816       rs773396699       rs773455637       rs773475930       rs773520355       rs773540732       rs773561521       rs773580636       rs773636480       rs773674301       rs773697871       rs773758589       rs773964046       rs773982485       rs773985446       rs774029483       rs774074425       rs774090044       rs774106186       rs774108286       rs774198361       rs774268322       rs774445853       rs774456131       rs774526529       rs774527730       rs774618454       rs774631916       rs774632732       rs774652725       rs774708289       rs774722544       rs774730018       rs774739991       rs774806393       rs774824065       rs774825320       rs774850991       rs774917444       rs774944402       rs775005316       rs775096314       rs775098882       rs775248247       rs775287178       rs775301798       rs775305075       rs775306650       rs775316652       rs775395973       rs775396578       rs775410119       rs775423188       rs775512879       rs775541705       rs775579020       rs775610069       rs775673941       rs775707777       rs775748980       rs775752574       rs775773140       rs775797796       rs775800723       rs775839096       rs775839108       rs775861285       rs775864422       rs775888851       rs775941303       rs775958233       rs775982815       rs775998211       rs776001781       rs776068781       rs776089627       rs776164041       rs776208420       rs776233976       rs776287958       rs776294514       rs776321867       rs776342497       rs776348555       rs776365510       rs776368408       rs776444400       rs776472721       rs776520958       rs776582750       rs776635313       rs776635926       rs776645014       rs776656630       rs776662773       rs776698238       rs776719332       rs776721688       rs776734701       rs776735390       rs776834258       rs776953380       rs777031030       rs777031095       rs777035527       rs777039218       rs777119063       rs777212939       rs777215483       rs777220375       rs777262952       rs777302965       rs777306756       rs777312045       rs777314897       rs777323416       rs777362098       rs777374967       rs777394889       rs777400327       rs777407982       rs777453960       rs777482773       rs777489526       rs777490947       rs777587946       rs777593580       rs777632795       rs777679213       rs777767025       rs777775550       rs777790961       rs777849794       rs777900381       rs777953631       rs777960988       rs777971266       rs778056727       rs778066260       rs778073934       rs778077380       rs778150854       rs778176623       rs778238599       rs778242972       rs778268218       rs778342323       rs778352013       rs778410810       rs778426779       rs778430208       rs778439395       rs778439967       rs778448957       rs778533958       rs778535322       rs778579061       rs778620376       rs778635560       rs778637760       rs778710470       rs778727499       rs778727661       rs778797374       rs778895295       rs778895520       rs778900479       rs778914975       rs778921734       rs778923400       rs778932663       rs778977106       rs779011730       rs779105492       rs779115360       rs779175583       rs779198191       rs779223180       rs779233612       rs779287393       rs779383911       rs779388255       rs779467211       rs779472569       rs779482827       rs779486305       rs779494078       rs779563059       rs779565843       rs779570938       rs779577312       rs779577754       rs779577932       rs779662126       rs779750198       rs779764475       rs779773258       rs779806061       rs779895747       rs779953545       rs779973027       rs779983651       rs780039723       rs780039794       rs780057189       rs780059745       rs780061413       rs780150317       rs780150770       rs780229182       rs780230705       rs780243231       rs780264345       rs780283322       rs780346558       rs780393922       rs780412888       rs780424998       rs780431299       rs780436447       rs780512843       rs780521410       rs780525374       rs780542164       rs780652577       rs780698636       rs780710402       rs780713235       rs780721859       rs780746554       rs780804336       rs780811948       rs780892258       rs780906946       rs780910147       rs780910847       rs780986775       rs781007758       rs781094866       rs781099520       rs781183372       rs781187596       rs781200820       rs781207275       rs781214624       rs781281420       rs781297964       rs781306481       rs781389440       rs781393986       rs781494336       rs781583134       rs781593831       rs781650994       rs781668145       rs781682249       rs781718560       rs781720212       rs867312666       rs869182200       rs869214588       rs869301325      

基因表达

基因表达

LPA基因在不同组织中的表达：    [UniProt]

基因在不同组织中的表达图

基因引物

基因引物

正向引物序列
正向引物Tm值
反向引物序列
反向引物Tm值
rank
TCCTTCTGAACAAGCACCA
59
GTGCCTTGATAACTCTGTCC
58
CTCCTTCTGAACAAGCACC
59
TGCCTTGATAACTCTGTCCA
59
TCCTTCTGAACAAGCACCA
59
ATGCCTCGATAACTCCGTC
59
TTCTGAACAAGCACCAACTG
59
TATGTGCCTTGATAACTCTGTC
58
TCCTTCTGAAGAAGCACCA
59
GTGCCTCGATAACTCTGTC
58
CCTTCTGAACAAGCACCAC
59
TATGCCTCGATAACTCCGTC
59
TTCTGAACAAGCACCAACTG
59
TATGTGCCTTGATAACTCTGTC
58
ATACTACCCAAATGCTGGCT
59
TCCCTCGTATAACAATAAGGAGC
60
ATACTACCCAAATGCTGGCT
59
TCCCTCGTATAACAATAAGGAGC
60
TCCTTCTGAACAAGCACCA
59
GTGCCTTGATAACTCTGTCC
58

转录因子

转录因子

      尚未收录相关数据

基因本体信息

LPA基因（以及对应的蛋白质）的细胞分布位置：

[UniProt]     [GenomeNet]

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • 溶酶体
  • 内涵体
  • 细胞核
  • 细胞质
  • 液泡
  • 细胞膜
  • 细胞外基质
  • 内质网
  • 线粒体
  • 高尔基体
  • 细胞骨架

LPA基因的本体（GO）信息：

GO库代码
对应的蛋白质
来源代码
GO:0001968
P08519(UniProtKB)
IPI
GO:0004252
P08519(UniProtKB)
IDA
GO:0004866
P08519(UniProtKB)
TAS
GO:0005515
P08519(UniProtKB)
IPI
GO:0005515
P08519(UniProtKB)
IPI
GO:0005515
P08519(UniProtKB)
IPI
GO:0005576
P08519(UniProtKB)
NAS
GO:0005576
P08519(UniProtKB)
TAS
GO:0006508
P08519(UniProtKB)
IEA
GO:0006629
P08519(UniProtKB)
NAS
GO:0006869
P08519(UniProtKB)
IEA
GO:0008015
P08519(UniProtKB)
TAS
GO:0008201
P08519(UniProtKB)
NAS
GO:0010951
P08519(UniProtKB)
IEA
GO:0034185
P08519(UniProtKB)
IPI
GO:0034358
P08519(UniProtKB)
IDA
GO:0042157
P08519(UniProtKB)
TAS

基因相互作用关系

基因相互作用关系

基因与其他基因之间的相互作用关系图
序号 作用方式 资源库来源/分值 基因名称 基因名称

基因相关microRNA

基因相关microRNA

可能调控LPA基因的相关microRNA：     

基因通路图

基因通路图

基因的通路属性图
通路基因列表

基因相关疾病

基因相关疾病

疾病名称 关系值 NofPmids NofSnps 来源
疾病名称 关系值 NofPmids NofSnps 来源
Coronary heart disease 0.271865777 52 5 BeFree_CTD_human_GAD_GWASCAT_LHGDN
Coronary Artery Disease 0.149865994 39 3 BeFree_CTD_human_GAD_LHGDN
Cerebrovascular accident 0.13570741 14 0 BeFree_CTD_human_GAD_LHGDN
Cardiovascular Diseases 0.133625632 18 0 BeFree_CTD_human_GAD_LHGDN
Atherosclerosis 0.132691755 31 0 BeFree_CTD_human_GAD_LHGDN
Hypercholesterolemia 0.120542884 3 0 BeFree_CTD_human
Thromboembolism 0.120271442 2 0 BeFree_CTD_human
Hypolipoproteinemias 0.12 1 0 CTD_human
Venous Thrombosis 0.12 1 0 CTD_human
Aortic valve calcification 0.12 1 1 GWASCAT
Lp(A) Deficiency, Congenital 0.12 0 1 CLINVAR
Myocardial Infarction 0.020912294 21 0 BeFree_GAD
Arteriosclerosis 0.010324723 29 0 BeFree_LHGDN
Coronary Arteriosclerosis 0.009229024 34 1 BeFree
Peripheral Vascular Diseases 0.008544182 5 0 BeFree_GAD_LHGDN
Diabetes Mellitus 0.003538676 4 1 BeFree_LHGDN
Diabetes Mellitus, Non-Insulin-Dependent 0.003452799 5 0 BeFree_GAD
Hypertensive disease 0.003267234 3 0 BeFree_LHGDN
Myocardial Ischemia 0.003181358 3 0 BeFree_GAD
Restenosis 0.003181358 4 0 BeFree_GAD
Carotid Artery Diseases 0.002909916 2 0 BeFree_GAD
Dyslipidemias 0.002909916 3 0 BeFree_GAD
Carotid Stenosis 0.00272435 1 0 LHGDN
Diabetic Nephropathy 0.00272435 1 0 LHGDN
Thrombosis 0.00272435 1 0 LHGDN
Arteriolosclerosis 0.00272435 1 0 LHGDN
Alzheimer's Disease 0.002638474 2 0 BeFree_GAD
Intracranial Aneurysm 0.002638474 1 0 BeFree_GAD
Obesity 0.002638474 2 0 BeFree_GAD
Liver carcinoma 0.002442977 9 0 BeFree
Amyotrophic Lateral Sclerosis 0.002367032 1 0 GAD
Asthma 0.002367032 1 0 GAD
Brain Ischemia 0.002367032 1 0 GAD
Chorioamnionitis 0.002367032 1 0 GAD
Fetal Membranes, Premature Rupture 0.002367032 1 0 GAD
Hypersensitivity 0.002367032 1 0 GAD
Premature Obstetric Labor 0.002367032 1 0 GAD
Pre-Eclampsia 0.002367032 1 0 GAD
Tobacco Use Disorder 0.002367032 1 0 GAD
Premature Birth 0.002367032 1 0 GAD
Metabolic Syndrome X 0.002367032 1 0 GAD
Venous Thromboembolism 0.002367032 1 0 GAD
Infection of amniotic sac and membranes, unspecified, unspecified trimester, not applicable or unspecified 0.002367032 1 0 GAD
Malignant neoplasm of breast 0.001900093 7 0 BeFree
Ovarian Carcinoma 0.001900093 7 0 BeFree
Malignant neoplasm of ovary 0.001900093 7 0 BeFree
Malignant tumor of colon 0.001628651 6 0 BeFree
Breast Carcinoma 0.001628651 6 0 BeFree
Colon Carcinoma 0.001628651 6 0 BeFree
Hypercholesterolemia, Familial 0.001085767 4 0 BeFree
Kidney Failure, Chronic 0.001085767 4 0 BeFree
Liver neoplasms 0.001085767 4 0 BeFree
Vascular Diseases 0.001085767 4 0 BeFree
Rheumatoid Arthritis 0.000814326 3 0 BeFree
Essential Hypertension 0.000814326 3 0 BeFree
Ischemic stroke 0.000814326 3 0 BeFree
Ischemic Cerebrovascular Accident 0.000814326 3 0 BeFree
Aortic Valve Stenosis 0.000542884 2 1 BeFree
Colorectal Carcinoma 0.000542884 2 0 BeFree
Dementia, Vascular 0.000542884 2 0 BeFree
Diabetes Mellitus, Insulin-Dependent 0.000542884 2 0 BeFree
Diabetic Retinopathy 0.000542884 2 0 BeFree
HIV Infections 0.000542884 2 0 BeFree
Hyperlipoproteinemias 0.000542884 2 0 BeFree
Kidney Diseases 0.000542884 2 0 BeFree
Nephrotic Syndrome 0.000542884 2 0 BeFree
Osteosarcoma 0.000542884 2 0 BeFree
Retinal Diseases 0.000542884 2 0 BeFree
Acute myocardial infarction 0.000542884 2 0 BeFree
Tumor Progression 0.000542884 2 0 BeFree
Polygenic hypercholesterolemia 0.000542884 2 0 BeFree
Malignant neoplasm of prostate 0.000542884 2 0 BeFree
Osteosarcoma of bone 0.000542884 2 0 BeFree
Carcinogenesis 0.000542884 2 0 BeFree
Prostate carcinoma 0.000542884 2 0 BeFree
Epithelial ovarian cancer 0.000542884 2 0 BeFree
ovarian neoplasm 0.000542884 2 0 BeFree
Peripheral Arterial Diseases 0.000542884 2 0 BeFree
Chronic kidney disease stage 5 0.000542884 2 0 BeFree
AORTIC VALVE DISEASE 2 0.000542884 2 1 BeFree
Amyloidosis 0.000271442 1 0 BeFree
Cooley's anemia 0.000271442 1 0 BeFree
Malignant neoplasm of urinary bladder 0.000271442 1 0 BeFree
Blood Coagulation Disorders 0.000271442 1 0 BeFree
Colonic Neoplasms 0.000271442 1 0 BeFree
Diabetes 0.000271442 1 1 BeFree
Experimental Autoimmune Encephalomyelitis 0.000271442 1 0 BeFree
Intermittent Claudication 0.000271442 1 1 BeFree
Chronic Lymphocytic Leukemia 0.000271442 1 0 BeFree
Acute Erythroblastic Leukemia 0.000271442 1 0 BeFree
Acute Promyelocytic Leukemia 0.000271442 1 0 BeFree
Malignant neoplasm of stomach 0.000271442 1 0 BeFree
Multiple Sclerosis 0.000271442 1 0 BeFree
Neoplasm Metastasis 0.000271442 1 0 BeFree
Pneumonia 0.000271442 1 0 BeFree
Pulmonary Embolism 0.000271442 1 0 BeFree
Kidney Failure 0.000271442 1 0 BeFree
Retinopathy of Prematurity 0.000271442 1 0 BeFree
Zellweger Syndrome 0.000271442 1 0 BeFree
AIDS-Associated Nephropathy 0.000271442 1 0 BeFree
Polycystic Kidney, Autosomal Dominant 0.000271442 1 0 BeFree
Gastrointestinal carcinoma 0.000271442 1 0 BeFree
Renal fibrosis 0.000271442 1 0 BeFree
Retinal ischemia 0.000271442 1 0 BeFree
Aortic Aneurysm, Abdominal 0.000271442 1 0 BeFree
Malignant ascites 0.000271442 1 0 BeFree
Calcific stenosis 0.000271442 1 6 BeFree
Cholesteryl Ester Transfer Protein Deficiency 0.000271442 1 0 BeFree
Multiple malignancy 0.000271442 1 0 BeFree
Alzheimer Disease, Late Onset 0.000271442 1 0 BeFree
Carotid Atherosclerosis 0.000271442 1 0 BeFree
Malignant neoplasm of gastrointestinal tract 0.000271442 1 0 BeFree
Stomach Carcinoma 0.000271442 1 0 BeFree
Carcinoma of bladder 0.000271442 1 0 BeFree
Acute Cerebrovascular Accidents 0.000271442 1 0 BeFree
Acute Coronary Syndrome 0.000271442 1 0 BeFree
Mammary Tumorigenesis 0.000271442 1 0 BeFree
Xenograft Model 0.000271442 1 0 BeFree
Colorectal Cancer 0.000271442 1 0 BeFree
Non-Malignant Ascites Adverse Event 0.000271442 1 0 BeFree
Idiopathic Pulmonary Fibrosis 0.000271442 1 0 BeFree
Thrombophilia, hereditary 0.000271442 1 0 BeFree

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