IVL基因详情-基因数据库-基因云馆

IVL(involucrin)

基因简称(symbol)

IVL [HGNC] [GeneCards] [NCBI]

基因种类(locus group)

protein-coding gene

同源简称(alias symbol)

基因家族代码(gene_family_id)

[HGNC] [GenScript]

omim代码

147360

entrez码

3713 [Vega]

vega基因码

OTTHUMG00000012451

ensembl基因码

ENSG00000163207 [Ensembl]

基因家族(gene family)

refseq数据库代号

NM_005547

更多...

基因种类(locus_type)

gene with protein product

基因名称状态(status)

Approved

location_sortable

01q21

同源基因名称(alias name)

基因名称批准使用时间(date_approved_reserved)

1986-01-01T00:00:00Z

基因简称更名时间(date_symbol_changed)

基因名称更名时间(date_name_changed)

更新时间(date_modified)

2014-11-19T00:00:00Z

ucsc码

uc001fau.3

ena

BC046391

ccds数据码

CCDS1030

uniprot数据码

P07476

pubmed代码

2873896

mgd码

rgd码

RGD:620141

生命科学数据库(lsdb)

更新时间(date modified)

2014-11-19T00:00:00Z

cosmic

IVL

mirbase

基因曾用简称(prev symbol)

基因曾用名称(prev name)

homeodb

cosmic

IVL

snornabase

bioparadigms slc

orphanet

假基因信息(pseudogeneorg)

horde id

merops

imgt

iuphar

kznf基因类别

mamit-trnadb

cd

LncRNA数据库

酶代码

中间纤维数据库

收起

1q21

Involucrin, a component of the keratinocyte crosslinked envelope, is found in the cytoplasm and crosslinked to membrane proteins by transglutaminase. This gene is mapped to 1q21, among calpactin I light chain, trichohyalin, profillaggrin, loricrin, and calcyclin. [provided by RefSeq, Jul 2008]

[中文简述(自动翻译):] Involucrin蛋白，角质形成细胞的交联外壳的一个组成部分，在细胞质中发现，通过转谷氨酰胺酶交联的膜蛋白。这个基因被映射到胃癌染色体1q21等位基因，其中calpactin我轻链，毛透明蛋白，profillaggrin，兜甲蛋白和钙周期蛋白。 [由RefSeq的，2008年7月提供]

OMIM数据库中对IVL基因的介绍 Wikipedia数据库中对IVL基因的介绍

IVL基因的碱基序列：[NCBI]

IVL基因的碱基突变：显示全部snp

rs913996 rs1854778 rs1854779 rs2229496 rs3820136 rs4459054 rs4523473 rs4845327 rs7517189 rs7520592 rs7520711 rs7528862 rs7535306 rs7539232 rs7541832 rs7545413 rs7545520 rs11205130 rs11205131 rs11205132 rs11205133 rs11205134 rs11205135 rs11205136 rs11205137 rs11807064 rs12035307 rs12038519 rs12045716 rs12239648 rs12240158 rs12406539 rs12407682 rs12565839 rs16834746 rs16834751 rs28542566

rs35088267 rs41272534 rs45544033 rs45609438 rs56809825 rs57263893 rs61731340 rs61731344 rs61731348 rs62637699 rs62641593 rs71582272 rs72704815 rs74130566 rs75111974 rs76513010 rs76701909 rs77867486 rs78748986 rs78959025 rs79573406 rs111814755 rs111888551 rs112069177 rs113196499 rs113727817 rs114429560 rs114448437 rs114747751 rs114911757 rs115821967 rs116288487 rs116373638 rs117106764 rs117787112 rs138618991 rs138980799 rs139585407 rs139703221 rs139775257 rs140142012 rs140682810 rs140811437 rs141266953 rs141431104 rs141684742 rs142137240 rs142358562 rs142865679 rs144429650 rs145144373 rs145270610 rs145430176 rs145659686 rs145817267 rs146112303 rs146331989 rs146342658 rs146429728 rs146658845 rs146972484 rs147215419 rs147448941 rs147621599 rs147769556 rs148853125 rs149718823 rs149812110 rs150130292 rs150294994 rs151164159 rs180686771 rs180930813 rs181436388 rs182267071 rs182325885 rs182629945 rs182821570 rs183714197 rs184035162 rs184046662 rs184389068 rs184811636 rs185217804 rs185349036 rs186598325 rs187266661 rs187778418 rs187958014 rs188421183 rs188763982 rs188859642 rs189567759 rs189815567 rs190091824 rs190444060 rs190594462 rs190623998 rs191978204 rs192044964 rs192209078 rs192400148 rs193050369 rs193143796 rs199703096 rs199771650 rs199989458 rs200220063 rs200245608 rs200427485 rs200641045 rs200731333 rs200798901 rs200916786 rs201099828 rs201247184 rs201279635 rs201303454 rs201506560 rs201668946 rs201867512 rs201971901 rs201996963 rs202036206 rs267598043 rs267598045 rs367633832 rs368043300 rs368119349 rs368244218 rs368432151 rs368649429 rs368936569 rs369041195 rs369992106 rs370156432 rs370441944 rs370790605 rs370858745 rs371220876 rs372109143 rs372278694 rs372498910 rs372740691 rs372928921 rs372959372 rs373006656 rs373177327 rs373783926 rs373993505 rs374105739 rs374478812 rs374818807 rs375026581 rs375636245 rs376206742 rs376485946 rs376869430 rs377070079 rs377655605 rs527371581 rs527529570 rs528120798 rs529211912 rs529782641 rs530210814 rs530902627 rs530995170 rs531377783 rs531442574 rs532183819 rs532299769 rs532645250 rs533009914 rs533345169 rs533415002 rs533585019 rs533817565 rs534004315 rs534435944 rs534740119 rs534874171 rs535134430 rs535192782 rs535332073 rs535618292 rs535730327 rs536297759 rs536859427 rs537295079 rs537560835 rs537562763 rs538782359 rs539289670 rs539514518 rs539768303 rs540298502 rs541453475 rs541702541 rs541736259 rs542047775 rs542470981 rs542504082 rs542527220 rs543668061 rs543706373 rs543718722 rs544298450 rs544703232 rs544718210 rs544854741 rs544900286 rs544910410 rs547475060 rs548478935 rs548566404 rs548651911 rs548703835 rs549516818 rs549847863 rs549912790 rs549937510 rs550939656 rs550968180 rs551501129 rs552096612 rs552623811 rs553100382 rs553952311 rs554905093 rs554942694 rs555091969 rs555363088 rs556018786 rs556097088 rs557152744 rs557425463 rs557477802 rs557754155 rs558262406 rs558273976 rs558349896 rs558880099 rs559254216 rs559617080 rs560052438 rs560240348 rs560558250 rs561281044 rs561646268 rs562226059 rs562349393 rs563496811 rs563858954 rs564521846 rs564611818 rs565397447 rs566689518 rs567142231 rs567518561 rs568330995 rs568474125 rs568581653 rs568708491 rs569146221 rs569599963 rs569686710 rs569843929 rs570614472 rs570684683 rs570877181 rs571035312 rs571146660 rs571736480 rs572279454 rs573458461 rs574760560 rs574898912 rs575913673 rs575915726 rs576032445 rs576967368 rs577206599 rs578014373 rs578125556 rs745528868 rs745829650 rs745869824 rs745982628 rs746362548 rs746372757 rs746404464 rs746463961 rs746661864 rs746856037 rs746939066 rs747169381 rs747334241 rs747420489 rs747459885 rs747787763 rs747787959 rs748096693 rs748273830 rs748318196 rs748794265 rs748800660 rs748965865 rs749233115 rs749295897 rs749410271 rs749997429 rs750115245 rs750193359 rs750645771 rs751318353 rs751351387 rs751802064 rs751933479 rs752525445 rs752772090 rs752971134 rs753559373 rs753903760 rs753907261 rs753907740 rs754153056 rs754241111 rs754578993 rs754737073 rs754776982 rs755108500 rs755216514 rs755306467 rs755346406 rs755422355 rs755767427 rs755858589 rs756203411 rs756282834 rs756472719 rs756832968 rs756949313 rs756991942 rs757205553 rs757645117 rs757759146 rs757788885 rs757987537 rs758203428 rs758333898 rs758335386 rs758398109 rs758627165 rs758780940 rs758984064 rs759113007 rs759360174 rs759435405 rs759571474 rs759798764 rs760000480 rs760318427 rs760459838 rs760551849 rs760699282 rs760921126 rs760969148 rs761460479 rs761615953 rs761644474 rs761914993 rs762285931 rs762866850 rs762947341 rs763173333 rs763348040 rs763508771 rs763773526 rs763781893 rs764131852 rs764232043 rs764273840 rs764634013 rs764808260 rs765002404 rs765004343 rs765155115 rs765290809 rs766107341 rs766328881 rs766749517 rs766833503 rs767144032 rs767400325 rs767403028 rs767421277 rs767490137 rs767679921 rs767807714 rs768249248 rs768338924 rs768339218 rs768438752 rs768558009 rs768718648 rs768762444 rs768883907 rs768919029 rs768973738 rs769197064 rs769238785 rs769362196 rs769401425 rs769950432 rs770046025 rs770299207 rs770351834 rs770970049 rs771011489 rs771057716 rs771405532 rs771417188 rs771663495 rs771866536 rs771903936 rs772208525 rs772356690 rs772448108 rs772577225 rs772658649 rs772658926 rs772745371 rs772747122 rs772751454 rs773123563 rs773600947 rs773777001 rs774120043 rs774545839 rs774830762 rs774832782 rs774958139 rs775028996 rs775102018 rs775154391 rs775208453 rs775991167 rs776225006 rs776241645 rs776300444 rs776607366 rs776644651 rs776726584 rs776839310 rs777113523 rs777114449 rs777396874 rs777417330 rs777790813 rs777811540 rs777901411 rs778089705 rs778646992 rs778827033 rs778918915 rs779238373 rs779870141 rs779879057 rs779883555 rs780252658 rs780258995 rs780340561 rs780409697 rs780556053 rs781413800 rs781508827 rs781590482 rs781731877

IVL基因在不同组织中的表达： [UniProt]

正向引物序列

正向引物Tm值

反向引物序列

反向引物Tm值

rank

TGAGTCTGGTTGACAGTAGC

59

CTTGAGGAGCTCCTGACTG

59

TGAGTCTGGTTGACAGTAGC

59

CAGTCTTGAGGAGCTCCTG

59

TGAGTCTGGTTGACAGTAGC

59

GTCTTGAGGAGCTCCTGAC

59

尚未收录相关数据

IVL基因（以及对应的蛋白质）的细胞分布位置：

[UniProt] [GenomeNet]

溶酶体
内涵体
细胞核
细胞质
液泡
细胞膜
细胞外基质
内质网
线粒体
高尔基体
细胞骨架

IVL基因的本体（GO）信息：

GO库代码

对应的蛋白质

来源代码

GO:0001533

P07476(UniProtKB)

IDA

GO:0005198

P07476(UniProtKB)

IDA

GO:0005198

P07476(UniProtKB)

IDA

GO:0005515

P07476(UniProtKB)

IPI

GO:0005737

P07476(UniProtKB)

IDA

GO:0005737

P07476(UniProtKB)

IDA

GO:0010224

P07476(UniProtKB)

IDA

GO:0018149

P07476(UniProtKB)

IDA

GO:0018153

P07476(UniProtKB)

TAS

GO:0030216

P07476(UniProtKB)

IDA

GO:0030674

P07476(UniProtKB)

IDA

GO:0031424

P07476(UniProtKB)

IEA

GO:0070062

P07476(UniProtKB)

IDA

序号	作用方式	资源库来源/分值	基因名称	基因名称

可能调控IVL基因的相关microRNA：

hsa-miR-335

通路基因列表

疾病名称

关系值

NofPmids

NofSnps

来源

疾病名称	关系值	NofPmids	NofSnps	来源
Squamous cell carcinoma	0.121357209	6	0	BeFree_CTD_human
Skin Neoplasms	0.12	1	0	CTD_human
Dermatitis, Atopic	0.005362824	2	0	BeFree_GAD_LHGDN
Psoriasis	0.001085767	4	0	BeFree
Cyst	0.000542884	2	0	BeFree
Esophageal Neoplasms	0.000542884	2	0	BeFree
Esophageal carcinoma	0.000542884	2	0	BeFree
Psoriasis vulgaris	0.000542884	2	0	BeFree
Malignant neoplasm of esophagus	0.000542884	2	0	BeFree
Squamous cell carcinoma of the head and neck	0.000542884	2	0	BeFree
Experimental Organism Basal Cell Carcinoma	0.000542884	2	0	BeFree
Eczema	0.000271442	1	0	BeFree
HIV Infections	0.000271442	1	0	BeFree
Lichen Sclerosus et Atrophicus	0.000271442	1	0	BeFree
Machado-Joseph Disease	0.000271442	1	0	BeFree
Hallopeau-Siemens Disease	0.000271442	1	0	BeFree
Familial benign pemphigus	0.000271442	1	0	BeFree
Tumor Progression	0.000271442	1	0	BeFree
Chloracne	0.000271442	1	0	BeFree
Cervix carcinoma	0.000271442	1	0	BeFree
Squamous intraepithelial lesion	0.000271442	1	0	BeFree
Erythrodermic lamellar ichthyosis	0.000271442	1	0	BeFree
Spinocerebellar Ataxia Type 1	0.000271442	1	0	BeFree
High Grade Intraepithelial Neoplasia	0.000271442	1	0	BeFree
Primary Carcinoma	0.000271442	1	0	BeFree
Malignant Conversion	0.000271442	1	0	BeFree
EPIDERMAL DIFFERENTIATION COMPLEX	0.000271442	1	0	BeFree