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HLA-E belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-E binds a restricted subset of peptides derived from the leader peptides of other class I molecules. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail. [provided by RefSeq, Jul 2008]
[中文简述(自动翻译):] HLA-E属于HLA I类重链旁系同源基??因。这个I类分子是由一个重链和一个轻链(β-2微球蛋白)的异源二聚体。重链被锚定在膜中。 HLA-E结合从其他我类分子的前导肽衍生肽受限制的子集。重链是大约45 kDa和其基因含有8个外显子。外显子1编码前导肽,外显子2和3编码的α1和α2结构域,其中两个结合肽,外显子4编码素α3域,外显子5编码跨膜区,和外显子6和7编码的胞质尾区。 [由RefSeq的,2008年7月提供]
HLA-E基因(以及对应的蛋白质)的细胞分布位置:
HLA-E基因的本体(GO)信息:
疾病名称 | 关系值 | NofPmids | NofSnps | 来源 |
Parapsoriasis | 0.12 | 1 | 0 | CTD_human |
Myocardial Ischemia | 0.080271442 | 2 | 0 | BeFree_CTD_mouse |
Diabetes Mellitus, Insulin-Dependent | 0.02904428 | 107 | 0 | BeFree |
Autoimmune Diseases | 0.028501397 | 105 | 0 | BeFree |
HIV Infections | 0.027806623 | 86 | 2 | BeFree_GAD |
Lupus Erythematosus, Systemic | 0.020825079 | 68 | 0 | BeFree_GAD |
melanoma | 0.02009663 | 65 | 0 | BeFree_LHGDN |
Rheumatoid Arthritis | 0.017100838 | 63 | 1 | BeFree |
Behcet Syndrome | 0.013625632 | 14 | 1 | BeFree_GAD_LHGDN |
Graft-vs-Host Disease | 0.012072926 | 19 | 0 | BeFree_GAD_LHGDN |
Multiple Sclerosis | 0.010857675 | 40 | 0 | BeFree |
Ankylosing spondylitis | 0.010510288 | 30 | 0 | BeFree_GAD |
Diabetes | 0.009229024 | 34 | 0 | BeFree |
Diabetes Mellitus | 0.009229024 | 34 | 0 | BeFree |
Psoriasis | 0.008338753 | 22 | 1 | BeFree_GAD |
Infection | 0.008173051 | 3 | 0 | LHGDN |
Celiac Disease | 0.006514605 | 24 | 0 | BeFree |
Virus Diseases | 0.005700279 | 21 | 0 | BeFree |
Malignant neoplasm of breast | 0.005428837 | 20 | 0 | BeFree |
Breast Carcinoma | 0.005428837 | 20 | 0 | BeFree |
Bare lymphocyte syndrome 2 | 0.005428837 | 20 | 0 | BeFree |
Bare Lymphocyte Syndrome | 0.005157396 | 19 | 0 | BeFree |
Anemia, Sickle Cell | 0.005091382 | 1 | 0 | GAD_LHGDN |
Gestational Diabetes | 0.005005506 | 3 | 0 | BeFree_GAD |
Cancer of Nasopharynx | 0.004734064 | 2 | 0 | GAD |
Graves Disease | 0.004614512 | 17 | 0 | BeFree |
Hepatitis B | 0.00434307 | 16 | 4 | BeFree |
Arthritis | 0.004071628 | 15 | 0 | BeFree |
Renal Cell Carcinoma | 0.004071628 | 15 | 0 | BeFree |
Colorectal Carcinoma | 0.003800186 | 14 | 0 | BeFree |
Experimental Autoimmune Encephalomyelitis | 0.003800186 | 14 | 0 | BeFree |
Hereditary hemochromatosis | 0.003800186 | 14 | 2 | BeFree |
Cardiomyopathy, Hypertrophic, Familial | 0.003800186 | 14 | 0 | BeFree |
Colon Carcinoma | 0.003528744 | 13 | 0 | BeFree |
Colorectal Cancer | 0.003528744 | 13 | 0 | BeFree |
Liver carcinoma | 0.003528744 | 13 | 0 | BeFree |
Tuberculosis | 0.003257302 | 12 | 0 | BeFree |
Mucocutaneous Lymph Node Syndrome | 0.003181358 | 3 | 0 | BeFree_GAD |
leukemia | 0.002985861 | 11 | 0 | BeFree |
Lymphoma | 0.002985861 | 11 | 0 | BeFree |
Myasthenia Gravis | 0.002985861 | 11 | 0 | BeFree |
Schizophrenia | 0.002985861 | 11 | 0 | BeFree |
Autoimmune thyroid disease | 0.002985861 | 11 | 0 | BeFree |
Bacterial Infections | 0.002909916 | 3 | 0 | BeFree_GAD |
Coronary Aneurysm | 0.002909916 | 2 | 0 | BeFree_GAD |
Neuroblastoma | 0.002714419 | 10 | 0 | BeFree |
Systemic Scleroderma | 0.002714419 | 10 | 0 | BeFree |
Cardiomyopathies | 0.002714419 | 10 | 0 | BeFree |
Nasopharyngeal carcinoma | 0.002714419 | 10 | 0 | BeFree |
Arthritis, Psoriatic | 0.002442977 | 9 | 0 | BeFree |
Malignant tumor of colon | 0.002442977 | 9 | 0 | BeFree |
Hemochromatosis | 0.002442977 | 9 | 2 | BeFree |
Hepatitis C | 0.002442977 | 9 | 0 | BeFree |
Malaria | 0.002442977 | 9 | 0 | BeFree |
Multiple Myeloma | 0.002442977 | 9 | 0 | BeFree |
Neoplasm Metastasis | 0.002442977 | 9 | 0 | BeFree |
Sarcoidosis | 0.002442977 | 9 | 1 | BeFree |
Diabetes, Autoimmune | 0.002442977 | 9 | 0 | BeFree |
Combined immunodeficiency | 0.002442977 | 9 | 0 | BeFree |
Central neuroblastoma | 0.002442977 | 9 | 0 | BeFree |
Juvenile rheumatoid arthritis | 0.002442977 | 9 | 0 | BeFree |
Spontaneous abortion | 0.002367032 | 1 | 0 | GAD |
Chorioamnionitis | 0.002367032 | 1 | 0 | GAD |
Fetal Membranes, Premature Rupture | 0.002367032 | 1 | 0 | GAD |
Premature Obstetric Labor | 0.002367032 | 1 | 0 | GAD |
Pre-Eclampsia | 0.002367032 | 1 | 0 | GAD |
Premature Birth | 0.002367032 | 1 | 0 | GAD |
Infection of amniotic sac and membranes, unspecified, unspecified trimester, not applicable or unspecified | 0.002367032 | 1 | 0 | GAD |
Primary biliary cirrhosis | 0.002171535 | 8 | 0 | BeFree |
Ulcerative Colitis | 0.002171535 | 8 | 0 | BeFree |
Glioma | 0.002171535 | 8 | 0 | BeFree |
Severe Combined Immunodeficiency | 0.002171535 | 8 | 0 | BeFree |
Hepatitis, Autoimmune | 0.002171535 | 8 | 0 | BeFree |
Tumor Immunity | 0.002171535 | 8 | 0 | BeFree |
Diabetes Mellitus, Non-Insulin-Dependent | 0.001900093 | 7 | 0 | BeFree |
Immunologic Deficiency Syndromes | 0.001900093 | 7 | 0 | BeFree |
Lupus Vulgaris | 0.001900093 | 7 | 0 | BeFree |
Lupus Erythematosus, Discoid | 0.001900093 | 7 | 0 | BeFree |
Lupus Erythematosus | 0.001900093 | 7 | 0 | BeFree |
Stomach Carcinoma | 0.001900093 | 7 | 0 | BeFree |
Hyperlipoproteinemia Type IIa | 0.001900093 | 7 | 0 | BeFree |
Juvenile arthritis | 0.001900093 | 7 | 0 | BeFree |
Squamous cell carcinoma | 0.001628651 | 6 | 0 | BeFree |
Common Variable Immunodeficiency | 0.001628651 | 6 | 0 | BeFree |
Crohn Disease | 0.001628651 | 6 | 3 | BeFree |
Influenza | 0.001628651 | 6 | 0 | BeFree |
Thyroiditis | 0.001628651 | 6 | 0 | BeFree |
Diffuse Large B-Cell Lymphoma | 0.001628651 | 6 | 0 | BeFree |
Immunoglobulin A deficiency (disorder) | 0.001628651 | 6 | 0 | BeFree |
Tumor Progression | 0.001628651 | 6 | 0 | BeFree |
Cervix carcinoma | 0.001628651 | 6 | 0 | BeFree |
Carcinogenesis | 0.001628651 | 6 | 0 | BeFree |
Prostate carcinoma | 0.001628651 | 6 | 0 | BeFree |
Spondylarthropathies | 0.001628651 | 6 | 0 | BeFree |
Arthritis, Collagen-Induced | 0.001628651 | 6 | 0 | BeFree |
Sarcoma | 0.001628651 | 6 | 0 | BeFree |
Immunoglobulin a deficiency 1 | 0.001628651 | 6 | 0 | BeFree |
Hypertrophic Cardiomyopathy | 0.001357209 | 5 | 0 | BeFree |
Malignant tumor of cervix | 0.001357209 | 5 | 0 | BeFree |
Cytomegalovirus Infections | 0.001357209 | 5 | 0 | BeFree |
Scleroderma | 0.001357209 | 5 | 0 | BeFree |
Glioblastoma | 0.001357209 | 5 | 0 | BeFree |
IGA Glomerulonephritis | 0.001357209 | 5 | 0 | BeFree |
Inflammatory Bowel Diseases | 0.001357209 | 5 | 0 | BeFree |
Myeloid Leukemia, Chronic | 0.001357209 | 5 | 0 | BeFree |
Adult T-Cell Lymphoma/Leukemia | 0.001357209 | 5 | 0 | BeFree |
Malignant neoplasm of stomach | 0.001357209 | 5 | 0 | BeFree |
Myositis | 0.001357209 | 5 | 0 | BeFree |
Chagas Disease | 0.001357209 | 5 | 0 | BeFree |
Vitiligo | 0.001357209 | 5 | 0 | BeFree |
Psoriasis vulgaris | 0.001357209 | 5 | 0 | BeFree |
Malignant neoplasm of prostate | 0.001357209 | 5 | 0 | BeFree |
Primary immune deficiency disorder | 0.001357209 | 5 | 0 | BeFree |
Acute GVH disease | 0.001357209 | 5 | 0 | BeFree |
VITILIGO-ASSOCIATED MULTIPLE AUTOIMMUNE DISEASE SUSCEPTIBILITY 1 (finding) | 0.001357209 | 5 | 0 | BeFree |
Arteriosclerosis | 0.001085767 | 4 | 0 | BeFree |
Asthma | 0.001085767 | 4 | 0 | BeFree |
Atherosclerosis | 0.001085767 | 4 | 0 | BeFree |
Malignant neoplasm of urinary bladder | 0.001085767 | 4 | 0 | BeFree |
Non-Small Cell Lung Carcinoma | 0.001085767 | 4 | 0 | BeFree |
Congestive heart failure | 0.001085767 | 4 | 0 | BeFree |
Herpes Simplex Infections | 0.001085767 | 4 | 0 | BeFree |
Arthropathy | 0.001085767 | 4 | 0 | BeFree |
Leprosy | 0.001085767 | 4 | 0 | BeFree |
Chronic Lymphocytic Leukemia | 0.001085767 | 4 | 0 | BeFree |
Osteosarcoma | 0.001085767 | 4 | 0 | BeFree |
Thymoma | 0.001085767 | 4 | 0 | BeFree |
Tuberculosis, Pulmonary | 0.001085767 | 4 | 0 | BeFree |
Malignant neoplasm of testis | 0.001085767 | 4 | 0 | BeFree |
Malignant neoplasm of lung | 0.001085767 | 4 | 0 | BeFree |
Primary sclerosing cholangitis | 0.001085767 | 4 | 0 | BeFree |
Hashimoto Disease | 0.001085767 | 4 | 0 | BeFree |
Carcinoma of lung | 0.001085767 | 4 | 0 | BeFree |
Carcinoma of bladder | 0.001085767 | 4 | 0 | BeFree |
Inclusion Body Myopathy, Sporadic | 0.001085767 | 4 | 0 | BeFree |
Autoimmune thyroiditis | 0.001085767 | 4 | 0 | BeFree |
Spondylarthritis | 0.001085767 | 4 | 0 | BeFree |
Astrocytoma | 0.000814326 | 3 | 0 | BeFree |
Autistic Disorder | 0.000814326 | 3 | 0 | BeFree |
Bipolar Disorder | 0.000814326 | 3 | 0 | BeFree |
Cardiomyopathy, Dilated | 0.000814326 | 3 | 0 | BeFree |
Choriocarcinoma | 0.000814326 | 3 | 0 | BeFree |
Cystic Fibrosis | 0.000814326 | 3 | 0 | BeFree |
Heart failure | 0.000814326 | 3 | 0 | BeFree |
Hepatitis | 0.000814326 | 3 | 0 | BeFree |
Hepatitis A | 0.000814326 | 3 | 0 | BeFree |
Immune System Diseases | 0.000814326 | 3 | 0 | BeFree |
Acute Promyelocytic Leukemia | 0.000814326 | 3 | 0 | BeFree |
Liver neoplasms | 0.000814326 | 3 | 0 | BeFree |
Myopathy | 0.000814326 | 3 | 0 | BeFree |
Muscular Dystrophy | 0.000814326 | 3 | 0 | BeFree |
Myocarditis | 0.000814326 | 3 | 0 | BeFree |
Narcolepsy | 0.000814326 | 3 | 0 | BeFree |
Ovarian Carcinoma | 0.000814326 | 3 | 0 | BeFree |
Pemphigus | 0.000814326 | 3 | 0 | BeFree |
Pemphigus Vulgaris | 0.000814326 | 3 | 0 | BeFree |
Stevens-Johnson Syndrome | 0.000814326 | 3 | 0 | BeFree |
Uveitis | 0.000814326 | 3 | 0 | BeFree |
Vasculitis | 0.000814326 | 3 | 0 | BeFree |
B-Cell Lymphomas | 0.000814326 | 3 | 0 | BeFree |
Polymyositis | 0.000814326 | 3 | 0 | BeFree |
Cutaneous Melanoma | 0.000814326 | 3 | 0 | BeFree |
Polyarthritis | 0.000814326 | 3 | 0 | BeFree |
Adult type dermatomyositis | 0.000814326 | 3 | 0 | BeFree |
Inclusion Body Myositis (disorder) | 0.000814326 | 3 | 0 | BeFree |
Spastic syndrome | 0.000814326 | 3 | 0 | BeFree |
Cervical Squamous Cell Carcinoma | 0.000814326 | 3 | 0 | BeFree |
Solid tumour | 0.000814326 | 3 | 0 | BeFree |
Seropositive rheumatoid arthritis | 0.000814326 | 3 | 0 | BeFree |
Hepatitis C, Chronic | 0.000814326 | 3 | 0 | BeFree |
Toxic Shock Syndrome | 0.000814326 | 3 | 0 | BeFree |
Diffuse panbronchiolitis | 0.000814326 | 3 | 0 | BeFree |
Malignant neoplasm of ovary | 0.000814326 | 3 | 0 | BeFree |
Epithelioma | 0.000814326 | 3 | 0 | BeFree |
Renal carcinoma | 0.000814326 | 3 | 0 | BeFree |
Coronary Artery Disease | 0.000814326 | 3 | 0 | BeFree |
Staphylococcal toxic shock syndrome | 0.000814326 | 3 | 0 | BeFree |
Adenocarcinoma | 0.000542884 | 2 | 0 | BeFree |
Alopecia Areata | 0.000542884 | 2 | 0 | BeFree |
Aspergillosis, Allergic Bronchopulmonary | 0.000542884 | 2 | 0 | BeFree |
Cardiovascular Diseases | 0.000542884 | 2 | 0 | BeFree |
Colorectal Neoplasms | 0.000542884 | 2 | 0 | BeFree |
Cowpox | 0.000542884 | 2 | 0 | BeFree |
Dental caries | 0.000542884 | 2 | 0 | BeFree |
Dermatomyositis | 0.000542884 | 2 | 0 | BeFree |
Muscular Dystrophy, Duchenne | 0.000542884 | 2 | 0 | BeFree |
Fatigue | 0.000542884 | 2 | 0 | BeFree |
Fibrosarcoma | 0.000542884 | 2 | 0 | BeFree |
Hematological Disease | 0.000542884 | 2 | 0 | BeFree |
Hypothyroidism | 0.000542884 | 2 | 0 | BeFree |
Kidney Failure, Chronic | 0.000542884 | 2 | 0 | BeFree |
Leishmaniasis | 0.000542884 | 2 | 0 | BeFree |
Acute lymphocytic leukemia | 0.000542884 | 2 | 0 | BeFree |
Leukemia, Myelocytic, Acute | 0.000542884 | 2 | 0 | BeFree |
Myeloid Leukemia | 0.000542884 | 2 | 0 | BeFree |
Leukemia, T-Cell | 0.000542884 | 2 | 0 | BeFree |
Lichen Planus | 0.000542884 | 2 | 0 | BeFree |
Chronic Obstructive Airway Disease | 0.000542884 | 2 | 0 | BeFree |
Lymphopenia | 0.000542884 | 2 | 0 | BeFree |
Paroxysmal nocturnal hemoglobinuria | 0.000542884 | 2 | 0 | BeFree |
Measles | 0.000542884 | 2 | 0 | BeFree |
Mitral Valve Stenosis | 0.000542884 | 2 | 0 | BeFree |
Mycoplasma Infections | 0.000542884 | 2 | 0 | BeFree |
Obesity | 0.000542884 | 2 | 0 | BeFree |
Bullous pemphigoid | 0.000542884 | 2 | 0 | BeFree |
Periodontitis | 0.000542884 | 2 | 0 | BeFree |
Respiratory Syncytial Virus Infections | 0.000542884 | 2 | 0 | BeFree |
Retinoblastoma | 0.000542884 | 2 | 0 | BeFree |
Rheumatic Heart Disease | 0.000542884 | 2 | 0 | BeFree |
synovial sarcoma | 0.000542884 | 2 | 0 | BeFree |
Thyroid Diseases | 0.000542884 | 2 | 0 | BeFree |
Typhoid Fever | 0.000542884 | 2 | 1 | BeFree |
Vascular Diseases | 0.000542884 | 2 | 0 | BeFree |
Arthritis, Reactive | 0.000542884 | 2 | 0 | BeFree |
Pancreatitis, Chronic | 0.000542884 | 2 | 0 | BeFree |
Left Ventricular Hypertrophy | 0.000542884 | 2 | 0 | BeFree |
Squamous cell carcinoma of lung | 0.000542884 | 2 | 0 | BeFree |
Small cell carcinoma of lung | 0.000542884 | 2 | 0 | BeFree |
Primary Sj�gren's syndrome | 0.000542884 | 2 | 0 | BeFree |
Secondary malignant neoplasm of lung | 0.000542884 | 2 | 0 | BeFree |
Malnutrition | 0.000542884 | 2 | 0 | BeFree |
Aortic Aneurysm, Thoracic | 0.000542884 | 2 | 0 | BeFree |
Teratocarcinoma | 0.000542884 | 2 | 0 | BeFree |
Uveal melanoma | 0.000542884 | 2 | 0 | BeFree |
X-linked agammaglobulinemia | 0.000542884 | 2 | 0 | BeFree |
Chronic berylliosis | 0.000542884 | 2 | 0 | BeFree |
Pemphigus and fogo selvagem | 0.000542884 | 2 | 0 | BeFree |
Metastatic Renal Cell Cancer | 0.000542884 | 2 | 0 | BeFree |
Metastatic melanoma | 0.000542884 | 2 | 0 | BeFree |
Squamous cell carcinoma of esophagus | 0.000542884 | 2 | 0 | BeFree |
Respiratory syncytial virus (RSV) infection in conditions classified elsewhere and of unspecified site | 0.000542884 | 2 | 0 | BeFree |
Immune thrombocytopenic purpura | 0.000542884 | 2 | 0 | BeFree |
Chronic active hepatitis | 0.000542884 | 2 | 0 | BeFree |
Hepatitis B, Chronic | 0.000542884 | 2 | 0 | BeFree |
Malignant melanoma of eye | 0.000542884 | 2 | 0 | BeFree |
Osteosarcoma of bone | 0.000542884 | 2 | 0 | BeFree |
Malignant neoplasm of kidney | 0.000542884 | 2 | 0 | BeFree |
Idiopathic Inflammatory Myopathies | 0.000542884 | 2 | 0 | BeFree |
Myasthenia Gravis, Autoimmune, Experimental | 0.000542884 | 2 | 0 | BeFree |
Chronic graft-versus-host disease | 0.000542884 | 2 | 0 | BeFree |
Alloimmunisation | 0.000542884 | 2 | 0 | BeFree |
Squamous cell carcinoma of the head and neck | 0.000542884 | 2 | 0 | BeFree |
Lymphocytic infiltration | 0.000542884 | 2 | 0 | BeFree |
Precursor B-cell lymphoblastic leukemia | 0.000542884 | 2 | 0 | BeFree |
Generalized vitiligo | 0.000542884 | 2 | 2 | BeFree |
Cardiomyopathy, Familial Idiopathic | 0.000542884 | 2 | 0 | BeFree |
Mammary Neoplasms | 0.000542884 | 2 | 0 | BeFree |
Glioblastoma Multiforme | 0.000542884 | 2 | 0 | BeFree |
Bone Sarcoma | 0.000542884 | 2 | 0 | BeFree |
Recurrent bacterial infection | 0.000542884 | 2 | 0 | BeFree |
Precursor Cell Lymphoblastic Leukemia Lymphoma | 0.000542884 | 2 | 0 | BeFree |
Chronic kidney disease stage 5 | 0.000542884 | 2 | 0 | BeFree |
Congenital adrenal hyperplasia due to 21 hydroxylase deficiency | 0.000542884 | 2 | 0 | BeFree |
Experimental Organism Basal Cell Carcinoma | 0.000542884 | 2 | 0 | BeFree |
Abscess | 0.000271442 | 1 | 0 | BeFree |
Addison Disease | 0.000271442 | 1 | 0 | BeFree |
Adrenal gland hypofunction | 0.000271442 | 1 | 0 | BeFree |
Anemia, Pernicious | 0.000271442 | 1 | 0 | BeFree |
Anthrax disease | 0.000271442 | 1 | 0 | BeFree |
Melanoma, B16 | 0.000271442 | 1 | 0 | BeFree |
Bone neoplasms | 0.000271442 | 1 | 0 | BeFree |
Brain Neoplasms | 0.000271442 | 1 | 0 | BeFree |
Malignant neoplasm of thyroid | 0.000271442 | 1 | 0 | BeFree |
Carcinoma, Transitional Cell | 0.000271442 | 1 | 0 | BeFree |
Cholangitis, Sclerosing | 0.000271442 | 1 | 0 | BeFree |
Hemophilia B | 0.000271442 | 1 | 0 | BeFree |
Colonic Neoplasms | 0.000271442 | 1 | 0 | BeFree |
Demyelinating Diseases | 0.000271442 | 1 | 0 | BeFree |
Mental Depression | 0.000271442 | 1 | 0 | BeFree |
Depressive disorder | 0.000271442 | 1 | 0 | BeFree |
Dermatitis Herpetiformis | 0.000271442 | 1 | 0 | BeFree |
Dermatitis, Atopic | 0.000271442 | 1 | 0 | BeFree |
Contact Dermatitis | 0.000271442 | 1 | 0 | BeFree |
Eczema | 0.000271442 | 1 | 0 | BeFree |
Toxic Epidermal Necrolysis | 0.000271442 | 1 | 0 | BeFree |
Erysipelothrix infection | 0.000271442 | 1 | 0 | BeFree |
Exanthema | 0.000271442 | 1 | 0 | BeFree |
Disorder of eye | 0.000271442 | 1 | 0 | BeFree |
Gingival Diseases | 0.000271442 | 1 | 0 | BeFree |
Glomerulonephritis | 0.000271442 | 1 | 0 | BeFree |
Goiter | 0.000271442 | 1 | 0 | BeFree |
Chronic granulomatous disease | 0.000271442 | 1 | 0 | BeFree |
Hay fever | 0.000271442 | 1 | 0 | BeFree |
Helminthiasis | 0.000271442 | 1 | 0 | BeFree |
Hemophilia A | 0.000271442 | 1 | 0 | BeFree |
Hepatitis, Chronic | 0.000271442 | 1 | 0 | BeFree |
Herpesviridae Infections | 0.000271442 | 1 | 0 | BeFree |
Malignant histiocytosis | 0.000271442 | 1 | 0 | BeFree |
Hodgkin Disease | 0.000271442 | 1 | 0 | BeFree |
Hyperinsulinism | 0.000271442 | 1 | 0 | BeFree |
Iridocyclitis | 0.000271442 | 1 | 0 | BeFree |
Listeriosis | 0.000271442 | 1 | 0 | BeFree |
Lupus Nephritis | 0.000271442 | 1 | 0 | BeFree |
Reticulosarcoma | 0.000271442 | 1 | 0 | BeFree |
Malaria, Falciparum | 0.000271442 | 1 | 0 | BeFree |
Meleda Disease | 0.000271442 | 1 | 0 | BeFree |
Mitral Valve Insufficiency | 0.000271442 | 1 | 0 | BeFree |
Mixed Salivary Gland Tumor | 0.000271442 | 1 | 0 | BeFree |
Myocardial Infarction | 0.000271442 | 1 | 0 | BeFree |
Nephritis | 0.000271442 | 1 | 0 | BeFree |
Osteomyelitis | 0.000271442 | 1 | 0 | BeFree |
Pancreatic Neoplasm | 0.000271442 | 1 | 0 | BeFree |
Pancytopenia | 0.000271442 | 1 | 0 | BeFree |
Tropical Spastic Paraparesis | 0.000271442 | 1 | 0 | BeFree |
Parasitic Diseases | 0.000271442 | 1 | 0 | BeFree |
Periodontal Diseases | 0.000271442 | 1 | 0 | BeFree |
Periodontitis, Juvenile | 0.000271442 | 1 | 0 | BeFree |
Precancerous Conditions | 0.000271442 | 1 | 0 | BeFree |
Pregnancy Complications | 0.000271442 | 1 | 0 | BeFree |
Prostatic Neoplasms | 0.000271442 | 1 | 0 | BeFree |
Protein Deficiency | 0.000271442 | 1 | 0 | BeFree |
Psychotic Disorders | 0.000271442 | 1 | 0 | BeFree |
Pulmonary Fibrosis | 0.000271442 | 1 | 0 | BeFree |
Henoch-Schoenlein Purpura | 0.000271442 | 1 | 0 | BeFree |
Retinal vascular occlusion | 0.000271442 | 1 | 0 | BeFree |
Retroviridae Infections | 0.000271442 | 1 | 0 | BeFree |
Rhabdomyosarcoma | 0.000271442 | 1 | 0 | BeFree |
Rosacea | 0.000271442 | 1 | 0 | BeFree |
Dermatologic disorders | 0.000271442 | 1 | 1 | BeFree |
Streptococcal Infections | 0.000271442 | 1 | 0 | BeFree |
Cerebrovascular accident | 0.000271442 | 1 | 0 | BeFree |
Giant Cell Arteritis | 0.000271442 | 1 | 0 | BeFree |
Toxoplasmosis, Congenital | 0.000271442 | 1 | 0 | BeFree |
Tuberous Sclerosis | 0.000271442 | 1 | 0 | BeFree |
Immunoblastic Large-Cell Lymphoma | 0.000271442 | 1 | 0 | BeFree |
Bronchial Hyperreactivity | 0.000271442 | 1 | 0 | BeFree |
Polyendocrinopathies, Autoimmune | 0.000271442 | 1 | 0 | BeFree |
Hypoplastic Left Heart Syndrome | 0.000271442 | 1 | 0 | BeFree |
Acute myocardial infarction | 0.000271442 | 1 | 0 | BeFree |
Allergic asthma | 0.000271442 | 1 | 0 | BeFree |
Liver Failure, Acute | 0.000271442 | 1 | 0 | BeFree |
MELAS Syndrome | 0.000271442 | 1 | 0 | BeFree |
Adenosquamous carcinoma | 0.000271442 | 1 | 0 | BeFree |
Giant Cell Tumor of Bone | 0.000271442 | 1 | 0 | BeFree |
Cervical Intraepithelial Neoplasia | 0.000271442 | 1 | 0 | BeFree |
Hydrosalpinx (disease) | 0.000271442 | 1 | 0 | BeFree |
Papillary thyroid carcinoma | 0.000271442 | 1 | 0 | BeFree |
Pemphigus Foliaceus | 0.000271442 | 1 | 0 | BeFree |
Dermatomyositis, Childhood Type | 0.000271442 | 1 | 0 | BeFree |
Congenital absence of adrenal gland | 0.000271442 | 1 | 0 | BeFree |
Renal glomerular disease | 0.000271442 | 1 | 0 | BeFree |
Impaired glucose tolerance | 0.000271442 | 1 | 0 | BeFree |
Postpartum Thyroiditis | 0.000271442 | 1 | 0 | BeFree |
Congenital immunodeficiency disease | 0.000271442 | 1 | 0 | BeFree |
Severe hereditary factor VIII deficiency disease | 0.000271442 | 1 | 0 | BeFree |
Mild hereditary factor VIII deficiency disease | 0.000271442 | 1 | 0 | BeFree |
Coinfection | 0.000271442 | 1 | 0 | BeFree |
Carcinoma breast stage IV | 0.000271442 | 1 | 0 | BeFree |
DS Stage I Plasma Cell Myeloma | 0.000271442 | 1 | 0 | BeFree |
Squamous cell carcinoma of tonsil | 0.000271442 | 1 | 0 | BeFree |
Iron Overload | 0.000271442 | 1 | 0 | BeFree |
Tumor necrosis | 0.000271442 | 1 | 0 | BeFree |
Anaplastic astrocytoma | 0.000271442 | 1 | 0 | BeFree |
Histiocytic sarcoma | 0.000271442 | 1 | 0 | BeFree |
Impaired cognition | 0.000271442 | 1 | 0 | BeFree |
Iodine deficiency syndrome | 0.000271442 | 1 | 0 | BeFree |
Hypophysitis | 0.000271442 | 1 | 0 | BeFree |
Multiple malignancy | 0.000271442 | 1 | 0 | BeFree |
Nonorganic psychosis | 0.000271442 | 1 | 0 | BeFree |
Cervical intraepithelial neoplasia grade 1 | 0.000271442 | 1 | 0 | BeFree |
Helicobacter pylori (H. pylori) infection in conditions classified elsewhere and of unspecified site | 0.000271442 | 1 | 0 | BeFree |
New Variant Creutzfeldt-Jakob Disease | 0.000271442 | 1 | 0 | BeFree |
Steroid-sensitive nephrotic syndrome | 0.000271442 | 1 | 0 | BeFree |
Adrenal cortical hypofunction | 0.000271442 | 1 | 0 | BeFree |
Actinic prurigo | 0.000271442 | 1 | 0 | BeFree |
Neonatal Systemic lupus erythematosus | 0.000271442 | 1 | 0 | BeFree |
Erythrokeratoderma | 0.000271442 | 1 | 0 | BeFree |
Hypersensitive syndrome | 0.000271442 | 1 | 0 | BeFree |
X-Linked Lymphoproliferative Disorder | 0.000271442 | 1 | 0 | BeFree |
Thyroid carcinoma | 0.000271442 | 1 | 0 | BeFree |
Oral infection | 0.000271442 | 1 | 0 | BeFree |
Factor V Leiden mutation | 0.000271442 | 1 | 0 | BeFree |
lung sarcoma | 0.000271442 | 1 | 0 | BeFree |
Monocytic leukemia | 0.000271442 | 1 | 0 | BeFree |
Complete hydatidiform mole | 0.000271442 | 1 | 0 | BeFree |
Malignant neoplasm of gastrointestinal tract | 0.000271442 | 1 | 0 | BeFree |
Acute anterior uveitis | 0.000271442 | 1 | 0 | BeFree |
Parasitic infection | 0.000271442 | 1 | 0 | BeFree |
Scleroderma, Limited | 0.000271442 | 1 | 0 | BeFree |
Multiple Sclerosis, Relapsing-Remitting | 0.000271442 | 1 | 0 | BeFree |
Lewy Body Disease | 0.000271442 | 1 | 0 | BeFree |
Gluten sensitivity | 0.000271442 | 1 | 0 | BeFree |
Helicobacter pylori infection | 0.000271442 | 1 | 0 | BeFree |
Carcinoma in situ of uterine cervix | 0.000271442 | 1 | 0 | BeFree |
21-hydroxylase deficiency | 0.000271442 | 1 | 0 | BeFree |
Immunodeficiency congenital | 0.000271442 | 1 | 0 | BeFree |
Invasive breast carcinoma | 0.000271442 | 1 | 0 | BeFree |
latent infection | 0.000271442 | 1 | 0 | BeFree |
Renal cancer metastatic | 0.000271442 | 1 | 0 | BeFree |
Myasthenias | 0.000271442 | 1 | 0 | BeFree |
Primary infection NOS | 0.000271442 | 1 | 0 | BeFree |
West Nile viral infection | 0.000271442 | 1 | 0 | BeFree |
Diffuse Scleroderma | 0.000271442 | 1 | 0 | BeFree |
Persistent infection | 0.000271442 | 1 | 0 | BeFree |
Sporadic porphyria cutanea tarda | 0.000271442 | 1 | 0 | BeFree |
Enthesitis | 0.000271442 | 1 | 0 | BeFree |
Inflammatory disorder | 0.000271442 | 1 | 0 | BeFree |
Herpes simplex type 1 infection | 0.000271442 | 1 | 0 | BeFree |
Autoimmune vasculitis | 0.000271442 | 1 | 0 | BeFree |
Classical Hodgkin's Lymphoma | 0.000271442 | 1 | 0 | BeFree |
Primary Carcinoma | 0.000271442 | 1 | 0 | BeFree |
Differentiated Thyroid Gland Carcinoma | 0.000271442 | 1 | 0 | BeFree |
Mixed Neoplasm | 0.000271442 | 1 | 0 | BeFree |
Primary Glioblastoma | 0.000271442 | 1 | 0 | BeFree |
Latent Tuberculosis | 0.000271442 | 1 | 0 | BeFree |
Inflammatory polyarthritis | 0.000271442 | 1 | 0 | BeFree |
Benign Prostatic Hyperplasia | 0.000271442 | 1 | 0 | BeFree |
Idiopathic Pulmonary Fibrosis | 0.000271442 | 1 | 0 | BeFree |
MAJOR AFFECTIVE DISORDER 2 | 0.000271442 | 1 | 0 | BeFree |
MAJOR AFFECTIVE DISORDER 1 | 0.000271442 | 1 | 0 | BeFree |
Birdshot chorioretinopathy | 0.000271442 | 1 | 0 | BeFree |
Severe Aplastic Anemia | 0.000271442 | 1 | 0 | BeFree |
Intravenous bisphosphonates | 0.000271442 | 1 | 0 | BeFree |
Myocardial Failure | 0.000271442 | 1 | 0 | BeFree |
MAJOR AFFECTIVE DISORDER 4 | 0.000271442 | 1 | 0 | BeFree |
MAJOR AFFECTIVE DISORDER 5 | 0.000271442 | 1 | 0 | BeFree |
MAJOR AFFECTIVE DISORDER 6 | 0.000271442 | 1 | 0 | BeFree |
ISS Stage I Plasma Cell Myeloma | 0.000271442 | 1 | 0 | BeFree |
Autoimmune pancreatitis | 0.000271442 | 1 | 0 | BeFree |
Myofibrillar Myopathy | 0.000271442 | 1 | 0 | BeFree |
MAJOR AFFECTIVE DISORDER 7 | 0.000271442 | 1 | 0 | BeFree |
MAJOR AFFECTIVE DISORDER 8 | 0.000271442 | 1 | 0 | BeFree |
MAJOR AFFECTIVE DISORDER 9 | 0.000271442 | 1 | 0 | BeFree |
Juvenile dermatomyositis | 0.000271442 | 1 | 0 | BeFree |
COMPLEMENT COMPONENT 4B DEFICIENCY | 0.000271442 | 1 | 0 | BeFree |
Complement Component 4a Deficiency | 0.000271442 | 1 | 0 | BeFree |
Plasmablastic lymphoma | 0.000271442 | 1 | 0 | BeFree |
Allergic disposition | 0.000271442 | 1 | 0 | BeFree |
AIDS (Disease) | 0.000271442 | 1 | 0 | BeFree |
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