ALDH3A1(aldehyde dehydrogenase 3 family, member A1) 转至新版数据库

基因简称(symbol)
    [HGNC]     [GeneCards]     [NCBI]
基因种类(locus group)
同源简称(alias symbol)
基因家族代码(gene_family_id)
    [HGNC]     [GenScript]
omim代码
entrez码
    [Vega]
vega基因码
ensembl基因码
    [Ensembl]
基因家族(gene family)
refseq数据库代号

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基因种类(locus_type)
基因名称状态(status)
location_sortable
同源基因名称(alias name)
基因名称批准使用时间(date_approved_reserved)
基因简称更名时间(date_symbol_changed)
基因名称更名时间(date_name_changed)
更新时间(date_modified)
ucsc码
ena
ccds数据码
uniprot数据码
pubmed代码
mgd码
rgd码
生命科学数据库(lsdb)
更新时间(date modified)
cosmic
mirbase
基因曾用简称(prev symbol)
基因曾用名称(prev name)
homeodb
cosmic
snornabase
bioparadigms slc
orphanet
假基因信息(pseudogeneorg)
horde id
merops
imgt
iuphar
kznf基因类别
mamit-trnadb
cd
LncRNA数据库
酶代码
中间纤维数据库

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17p11.2
基因染色体位置图

Aldehyde dehydrogenases oxidize various aldehydes to the corresponding acids. They are involved in the detoxification of alcohol-derived acetaldehyde and in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. The enzyme encoded by this gene forms a cytoplasmic homodimer that preferentially oxidizes aromatic and medium-chain (6 carbons or more) saturated and unsaturated aldehyde substrates. It is thought to promote resistance to UV and 4-hydroxy-2-nonenal-induced oxidative damage in the cornea. The gene is located within the Smith-Magenis syndrome region on chromosome 17. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Sep 2008]

[中文简述(自动翻译):]  醛脱氢酶氧化各种醛为相应的酸。它们参与醇衍生乙醛的解毒和皮质类固醇,生物胺,神经递质,和脂质过氧化的代谢。由该基因编码的酶形成饱和细胞质同型二聚体,其优先氧化芳族和中链(6个碳原子或更多个)和不饱和醛底物。它被认为是促进紫外线和在角膜4-羟基-2-壬烯醛诱导的氧化损伤性。该基因位于史密斯马盖尼斯综合征区域内染色体上17多个可变剪接变体,编码相同的蛋白质,也已确定。 [由RefSeq的,2008年9月提供]

ALDH3A1基因的碱基序列:[NCBI]
ALDH3A1基因的碱基突变:           显示全部snp
rs887239       rs887240       rs887241       rs917520       rs1042172       rs1042183       rs2072327       rs2072328       rs2072329       rs2072330       rs2228100       rs3744692       rs3744693       rs3744694       rs3744695       rs3760485       rs3760486       rs3760487       rs3760488       rs3786035       rs3786036       rs3786037       rs3826507       rs4646783       rs4646784       rs4646785       rs4646786       rs4646787       rs4646788       rs4646789       rs4646790       rs4646791       rs4646792       rs7209030       rs7216299       rs7221211       rs7221554      
rs11385990       rs11554974       rs11554977       rs11554978       rs12939864       rs12949049       rs12951039       rs16960378       rs16960382       rs28531080       rs28552545       rs56234923       rs56333309       rs57485106       rs57555435       rs57633837       rs58060020       rs58072200       rs58349304       rs59102760       rs59720526       rs60309529       rs60739355       rs60750445       rs61279095       rs67083835       rs72841925       rs72841927       rs73312707       rs73984110       rs74780319       rs75355613       rs75819168       rs76390606       rs77493077       rs77580286       rs77823659       rs78316825       rs79422749       rs79434246       rs79905857       rs79994225       rs111421525       rs111501205       rs111828936       rs111892609       rs112034368       rs112113341       rs112263426       rs112452365       rs112765783       rs112831562       rs113078423       rs113084632       rs113168621       rs113254239       rs113907319       rs114457153       rs114473912       rs114721010       rs115292854       rs115563042       rs115638369       rs115899325       rs116066736       rs116087608       rs116269339       rs116754663       rs116948535       rs116962241       rs116992290       rs117058916       rs117080575       rs117114051       rs117167872       rs117306414       rs117317042       rs117318955       rs117328009       rs117345529       rs117475050       rs117687479       rs117690879       rs117700665       rs118057522       rs118106687       rs118186183       rs137895975       rs137909977       rs138012937       rs138049344       rs138305312       rs138392076       rs138656076       rs138998524       rs139173953       rs139278361       rs139283720       rs140108064       rs140244873       rs140318101       rs140518422       rs140562527       rs140767140       rs140881083       rs140993882       rs141508989       rs141568499       rs141612566       rs141622022       rs141928580       rs141944650       rs142030321       rs142078447       rs142114670       rs142682649       rs142761764       rs142785160       rs143130305       rs143498365       rs143691519       rs143739303       rs143872646       rs144035368       rs144161169       rs144464192       rs144515136       rs144805447       rs145226141       rs145293763       rs145315016       rs145367472       rs145372783       rs145445256       rs145465198       rs145505711       rs145613099       rs145697414       rs145861787       rs145896313       rs146094687       rs146191728       rs146499259       rs146746671       rs147101721       rs147115158       rs147298045       rs147573068       rs147686367       rs147790087       rs148085286       rs148139496       rs148384522       rs148827495       rs149086635       rs149186544       rs149563628       rs149753259       rs149784212       rs149835317       rs150015448       rs150321309       rs150636822       rs150692942       rs150970681       rs151020632       rs151224002       rs151298179       rs180982008       rs181118535       rs181328091       rs181355397       rs181739884       rs181917287       rs181977780       rs182086116       rs182425984       rs183042465       rs183226242       rs183547957       rs183815089       rs184041073       rs184573863       rs185277445       rs185322422       rs185868653       rs185907130       rs186459345       rs186704435       rs186705171       rs187042941       rs188206464       rs188443874       rs188621742       rs189250288       rs189475952       rs189745524       rs189806390       rs190318336       rs191097564       rs191412592       rs191423134       rs191901361       rs192322658       rs192590322       rs192673104       rs193086040       rs199667643       rs199778751       rs200012428       rs200102864       rs200199114       rs200200301       rs200396225       rs200401527       rs200453129       rs200532620       rs200539114       rs200603438       rs200717464       rs200726755       rs200801296       rs201022888       rs201166581       rs201174820       rs201273273       rs201282651       rs201432261       rs201501891       rs201504992       rs201510717       rs201594817       rs201715060       rs201999351       rs202069113       rs202164433       rs367557611       rs367567625       rs367780076       rs368032568       rs368173034       rs368233404       rs368399148       rs368594259       rs368634302       rs368804107       rs368807570       rs368982561       rs369145420       rs369396278       rs369647404       rs370024697       rs370374404       rs370379937       rs370412178       rs370815018       rs370908746       rs371001198       rs371208073       rs371210688       rs371403304       rs371701018       rs371742779       rs371918916       rs372030724       rs372148589       rs372199210       rs372218695       rs372331356       rs372399759       rs372454117       rs372494751       rs372500641       rs372701645       rs372734283       rs373306549       rs373338484       rs373413179       rs373647477       rs374060290       rs374118874       rs374230530       rs374241489       rs374241717       rs374462271       rs374507907       rs374777561       rs374854383       rs375012774       rs375087315       rs375109089       rs375261051       rs375380124       rs375495827       rs375556355       rs375698521       rs375771662       rs375783415       rs375889932       rs375946144       rs376130132       rs376168688       rs376188654       rs376671939       rs376801126       rs376835472       rs376860900       rs376864834       rs376923194       rs377018930       rs377384082       rs377431592       rs377491348       rs377674119       rs527248552       rs527427687       rs527899907       rs528422510       rs528926517       rs529578187       rs529665647       rs530003566       rs530427297       rs531350661       rs531477514       rs531898438       rs532015947       rs532511984       rs532568627       rs532616896       rs533089949       rs533116559       rs533177553       rs533298718       rs533309462       rs533556157       rs534184788       rs534470915       rs534507817       rs534933625       rs535363045       rs535528669       rs535542066       rs535615769       rs536106180       rs536327164       rs536610150       rs536804477       rs537008073       rs537010194       rs537038816       rs537270365       rs537463059       rs537780681       rs537868369       rs538236208       rs538393317       rs538577979       rs539213892       rs539431177       rs539443107       rs539635463       rs540496945       rs540633466       rs540850435       rs541642700       rs541724789       rs542078387       rs542345176       rs542453997       rs542464129       rs542863527       rs542918803       rs543186487       rs543412845       rs543542339       rs543615839       rs543788431       rs543988086       rs543999159       rs544273331       rs544485155       rs544620393       rs544669507       rs544808623       rs545679214       rs545815877       rs545856620       rs545990205       rs546813607       rs547051379       rs547245530       rs547704613       rs548063721       rs548157710       rs548172023       rs548349445       rs548408383       rs548572365       rs549169871       rs549355529       rs549534197       rs549743110       rs549751885       rs549972913       rs550569625       rs550835521       rs551002574       rs551851263       rs552045562       rs552163756       rs552355123       rs552979670       rs552989421       rs552996105       rs553211794       rs553225464       rs553268659       rs553990483       rs554189385       rs554198397       rs554254701       rs554512806       rs555443127       rs555784179       rs555835233       rs555970410       rs556435605       rs557023654       rs557034887       rs557108061       rs557158355       rs557323547       rs557774317       rs558170234       rs558379983       rs558605589       rs558945262       rs559439303       rs559729109       rs560206867       rs560446027       rs560469733       rs560578548       rs560665215       rs560832752       rs561218301       rs561824134       rs562444690       rs562569604       rs563162965       rs563379597       rs563465351       rs563592569       rs564024276       rs564394775       rs564599718       rs564661903       rs565535963       rs565597915       rs565704674       rs565859221       rs566221301       rs566430834       rs566703357       rs567021563       rs567055361       rs567656425       rs567741792       rs568128175       rs568211831       rs568426151       rs568618148       rs568799554       rs569205857       rs569295583       rs569474470       rs569611395       rs569989170       rs570560991       rs570592149       rs570805569       rs571850692       rs572001443       rs572087671       rs572555574       rs572741359       rs572977809       rs574015231       rs574046532       rs574304007       rs574514289       rs574666635       rs575647405       rs575714241       rs576269061       rs576792452       rs576909267       rs576909305       rs576939107       rs576992677       rs577383598       rs577461362       rs577939509       rs577984180       rs578049503       rs745330622       rs745422678       rs745520004       rs745609991       rs745610092       rs745769411       rs745863174       rs746087911       rs746107983       rs746113507       rs746359941       rs746369217       rs746437928       rs746438998       rs746635894       rs746652504       rs747035030       rs747202576       rs747202757       rs747256411       rs747290788       rs747379738       rs747570938       rs747613567       rs747724829       rs747774379       rs748016437       rs748021671       rs748050180       rs748200146       rs748220822       rs748330544       rs748398774       rs748460974       rs748462955       rs748624316       rs748688486       rs748884426       rs748915489       rs749037091       rs749245878       rs749325435       rs749417531       rs749473875       rs749505030       rs749526257       rs749777373       rs749818603       rs749825029       rs749862833       rs749894728       rs749982465       rs749985245       rs750075822       rs750075912       rs750078082       rs750129797       rs750375117       rs750383473       rs750423189       rs750543026       rs750559783       rs750852050       rs750958007       rs750965150       rs750984975       rs751025286       rs751128591       rs751169513       rs751220464       rs751237549       rs751274826       rs751446624       rs751526409       rs751526560       rs751540130       rs751544540       rs751684503       rs751722274       rs751834346       rs751939838       rs752001006       rs752001727       rs752015753       rs752281981       rs752328723       rs752483408       rs752675141       rs752676127       rs752901351       rs752903104       rs752921553       rs753083542       rs753175531       rs753394468       rs753516017       rs753634547       rs753741018       rs753741853       rs753756012       rs753846025       rs753916005       rs753968946       rs754055250       rs754122948       rs754146486       rs754226704       rs754303573       rs754303931       rs754435198       rs754526583       rs754591414       rs754593409       rs754595647       rs754646038       rs754682982       rs754834006       rs754920415       rs754938166       rs755108751       rs755250908       rs755519068       rs755560571       rs755607140       rs755608749       rs755646383       rs756093804       rs756164830       rs756174714       rs756253107       rs756334935       rs756357538       rs756374004       rs756530717       rs756715535       rs756727090       rs756727409       rs756737290       rs757032351       rs757115562       rs757324643       rs757328458       rs757352910       rs757385068       rs757438230       rs757470015       rs757597237       rs757659230       rs757670168       rs757794756       rs757820701       rs757931947       rs757969249       rs758126332       rs758287966       rs758537548       rs758589250       rs758637333       rs758954521       rs758998154       rs759014850       rs759044533       rs759178925       rs759195839       rs759203617       rs759214044       rs759276441       rs759435723       rs759574534       rs759633710       rs759731579       rs759823213       rs759845212       rs759901954       rs759937616       rs760027682       rs760061558       rs760112160       rs760255479       rs760289299       rs760303323       rs760336161       rs760407426       rs760495322       rs760732917       rs761024087       rs761037328       rs761053994       rs761055890       rs761145572       rs761158700       rs761176930       rs761182940       rs761187992       rs761232139       rs761244242       rs761638389       rs761658728       rs761724950       rs761854938       rs762182523       rs762195039       rs762196648       rs762203999       rs762285163       rs762371378       rs762487201       rs762581742       rs762632301       rs762768333       rs762887533       rs762937288       rs762977522       rs762980938       rs763270082       rs763299224       rs763324625       rs763351612       rs763498496       rs763539601       rs763570276       rs763629080       rs763700087       rs763895608       rs763924725       rs763939016       rs763974208       rs763976487       rs764054865       rs764159674       rs764176145       rs764246248       rs764247730       rs764357572       rs764376037       rs764380687       rs764668200       rs764747434       rs765020206       rs765049018       rs765106070       rs765313700       rs765521546       rs765608757       rs765863902       rs765883330       rs765889019       rs765908428       rs766272845       rs766289222       rs766341383       rs766539011       rs766638702       rs766845006       rs766865186       rs766871933       rs766922092       rs767075183       rs767114108       rs767162387       rs767315128       rs767405009       rs767419168       rs767437574       rs767580208       rs767646732       rs767745410       rs767794222       rs768109284       rs768205113       rs768221550       rs768288206       rs768288640       rs768369860       rs768378254       rs768618591       rs768634987       rs768647335       rs768971546       rs769016246       rs769100782       rs769105899       rs769106344       rs769413564       rs769552132       rs769604016       rs769768762       rs769769129       rs769856693       rs769924949       rs770133924       rs770247968       rs770423248       rs770489591       rs770598190       rs770617828       rs770654987       rs770855094       rs770963389       rs771070366       rs771158395       rs771162561       rs771212258       rs771318428       rs771321411       rs771373427       rs771543126       rs771640925       rs771740622       rs771798612       rs771807870       rs771884353       rs771902173       rs772081401       rs772284661       rs772307348       rs772340321       rs772364547       rs772372375       rs772414920       rs772607043       rs772615188       rs772824617       rs772923402       rs772975076       rs773011504       rs773183036       rs773492019       rs773640943       rs773739072       rs773761996       rs773789433       rs774074300       rs774092621       rs774198203       rs774212642       rs774324168       rs774423061       rs774444883       rs774533268       rs774582773       rs774623416       rs774852285       rs774944676       rs774954930       rs775040136       rs775235326       rs775334611       rs775334881       rs775426468       rs775620094       rs775719695       rs775761062       rs775775554       rs775794171       rs775915367       rs775985096       rs776003538       rs776102082       rs776289387       rs776294769       rs776374305       rs776458388       rs776492802       rs776555342       rs776579263       rs776838494       rs776900761       rs776920097       rs776938032       rs777078271       rs777181749       rs777224011       rs777314022       rs777415702       rs777628642       rs777718532       rs777811199       rs778065297       rs778081851       rs778166358       rs778409417       rs778545859       rs778623472       rs778633741       rs778654435       rs778744795       rs778904408       rs778928296       rs779215136       rs779314973       rs779319405       rs779346208       rs779433897       rs779531243       rs779629873       rs779789522       rs779805732       rs779986721       rs780058736       rs780097427       rs780153341       rs780256433       rs780285968       rs780440062       rs780443108       rs780451866       rs780557876       rs780669392       rs780760675       rs780825276       rs780939059       rs781135696       rs781146893       rs781201910       rs781258287       rs781349167       rs781403316       rs781418978       rs781475117       rs781495693       rs781507152       rs781593967       rs781738420      

ALDH3A1基因在不同组织中的表达:    [UniProt]

基因在不同组织中的表达图
正向引物序列
正向引物Tm值
反向引物序列
反向引物Tm值
rank
CCTGCACAAGAATGAATGGA
59
GATCTCCTCTAGGACGTACAC
59
ATGCAAGAGGAGATCTTCG
57
CTTAATCACCTTGTCGTTGC
58
ATGCAAGAGGAGATCTTCG
57
CTTAATCACCTTGTCGTTGC
58
GCTGTGTCAAAGAATGAATGG
58
GCTTCTGGATCATGTACTCG
58
CCCTGACTACATCCTCTGTG
59
CCGAAGATCTCTTTCAGTGAC
59
TGCAAGAGGAGATCTTCGG
59
TCTTAATCACCTTGTCGTTGC
59
CCTGCACAAGAATGAATGG
57
GATCTCCTCTAGGACGTACAC
59
TGCAAGAGGAGATCTTCGG
59
CTTAATCACCTTGTCGTTGCT
59
TCACTGAAAGAGTTCTACGGG
60
CCATCACCCTCTGGAAGTG
60
AGTCACTGAAAGAGTTCTACGG
60
CCATCACCCTCTGGAAGTG
60
      尚未收录相关数据

ALDH3A1基因(以及对应的蛋白质)的细胞分布位置:

[UniProt]     [GenomeNet]

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • 溶酶体
  • 内涵体
  • 细胞核
  • 细胞质
  • 液泡
  • 细胞膜
  • 细胞外基质
  • 内质网
  • 线粒体
  • 高尔基体
  • 细胞骨架

ALDH3A1基因的本体(GO)信息:

GO库代码
对应的蛋白质
来源代码
GO:0005654
A8MYB8(UniProtKB)
IDA
GO:0005737
A8MYB8(UniProtKB)
IDA
GO:0005886
A8MYB8(UniProtKB)
IDA
GO:0016620
A8MYB8(UniProtKB)
IEA
GO:0043231
A8MYB8(UniProtKB)
IDA
GO:0055114
A8MYB8(UniProtKB)
IEA
GO:0005654
C9JKT2(UniProtKB)
IDA
GO:0005737
C9JKT2(UniProtKB)
IDA
GO:0016620
C9JKT2(UniProtKB)
IEA
GO:0043231
C9JKT2(UniProtKB)
IDA
GO:0055114
C9JKT2(UniProtKB)
IEA
GO:0005654
C9JMC5(UniProtKB)
IDA
GO:0005737
C9JMC5(UniProtKB)
IDA
GO:0016620
C9JMC5(UniProtKB)
IEA
GO:0043231
C9JMC5(UniProtKB)
IDA
GO:0055114
C9JMC5(UniProtKB)
IEA
GO:0016620
E9PNN6(UniProtKB)
IEA
GO:0055114
E9PNN6(UniProtKB)
IEA
GO:0005654
I3L1H6(UniProtKB)
IDA
GO:0005737
I3L1H6(UniProtKB)
IDA
GO:0016491
I3L1H6(UniProtKB)
IEA
GO:0043231
I3L1H6(UniProtKB)
IDA
GO:0055114
I3L1H6(UniProtKB)
IEA
GO:0005737
I3L3I9(UniProtKB)
IDA
GO:0005886
I3L3I9(UniProtKB)
IDA
GO:0016620
I3L3I9(UniProtKB)
IEA
GO:0055114
I3L3I9(UniProtKB)
IEA
GO:0016491
I3L3W9(UniProtKB)
IEA
GO:0055114
I3L3W9(UniProtKB)
IEA
GO:0005654
I3L4E5(UniProtKB)
IDA
GO:0005737
I3L4E5(UniProtKB)
IDA
GO:0016491
I3L4E5(UniProtKB)
IEA
GO:0043231
I3L4E5(UniProtKB)
IDA
GO:0055114
I3L4E5(UniProtKB)
IEA
GO:0001666
P30838(UniProtKB)
IEA
GO:0004028
P30838(UniProtKB)
IBA
GO:0004029
P30838(UniProtKB)
IDA
GO:0004030
P30838(UniProtKB)
TAS
GO:0005515
P30838(UniProtKB)
IPI
GO:0005615
P30838(UniProtKB)
IDA
GO:0005654
P30838(UniProtKB)
IDA
GO:0005737
P30838(UniProtKB)
IDA
GO:0005783
P30838(UniProtKB)
IDA
GO:0005829
P30838(UniProtKB)
ISS
GO:0005829
P30838(UniProtKB)
TAS
GO:0005886
P30838(UniProtKB)
IDA
GO:0006081
P30838(UniProtKB)
IDA
GO:0006805
P30838(UniProtKB)
TAS
GO:0007568
P30838(UniProtKB)
IEA
GO:0007584
P30838(UniProtKB)
IEA
GO:0008106
P30838(UniProtKB)
IDA
GO:0008284
P30838(UniProtKB)
IEA
GO:0016021
P30838(UniProtKB)
IEA
GO:0018479
P30838(UniProtKB)
IDA
GO:0042493
P30838(UniProtKB)
IEA
GO:0043231
P30838(UniProtKB)
IDA
GO:0051384
P30838(UniProtKB)
IEA
GO:0051591
P30838(UniProtKB)
IEA
GO:0055114
P30838(UniProtKB)
IDA
基因与其他基因之间的相互作用关系图
序号 作用方式 资源库来源/分值 基因名称 基因名称

可能调控ALDH3A1基因的相关microRNA:     


通路基因列表
疾病名称 关系值 NofPmids NofSnps 来源
疾病名称 关系值 NofPmids NofSnps 来源
Malignant neoplasm of breast 0.005005506 3 0 BeFree_GAD
Lung Neoplasms 0.002995792 2 0 BeFree_LHGDN
Schizophrenia 0.002638474 1 0 BeFree_GAD
Autistic Disorder 0.002367032 1 0 GAD
Neoplasms, Germ Cell and Embryonal 0.002367032 1 0 GAD
Tobacco Use Disorder 0.002367032 1 0 GAD
childhood brain tumor 0.002367032 1 0 GAD
ovarian neoplasm 0.002367032 1 0 GAD
Mammary Neoplasms 0.002367032 1 0 GAD
Liver carcinoma 0.001357209 5 0 BeFree
Non-Small Cell Lung Carcinoma 0.000542884 2 0 BeFree
Pterygium 0.000542884 2 0 BeFree
Adenocarcinoma of lung (disorder) 0.000542884 2 0 BeFree
Mental Depression 0.000271442 1 0 BeFree
Depressive disorder 0.000271442 1 0 BeFree
Glioblastoma 0.000271442 1 0 BeFree
Liver neoplasms 0.000271442 1 0 BeFree
Neoplasm Metastasis 0.000271442 1 0 BeFree
Hemorrhagic cystitis 0.000271442 1 0 BeFree
Cataract 0.000271442 1 0 BeFree
Secondary malignant neoplasm of lung 0.000271442 1 0 BeFree
Recurrent pterygium 0.000271442 1 0 BeFree
Hepatocellular Adenoma 0.000271442 1 0 BeFree
Malignant neoplasm of lung 0.000271442 1 0 BeFree
Malignant neoplasm of prostate 0.000271442 1 0 BeFree
Bilateral cataracts (disorder) 0.000271442 1 0 BeFree
Prostate carcinoma 0.000271442 1 0 BeFree
Breast adenocarcinoma 0.000271442 1 0 BeFree
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