CD3D(CD3d molecule, delta (CD3-TCR complex)) 转至新版数据库

基因基本信息

基因基本信息

基因简称(symbol)
    [HGNC]     [GeneCards]     [NCBI]
基因种类(locus group)
同源简称(alias symbol)
基因家族代码(gene_family_id)
    [HGNC]     [GenScript]
omim代码
entrez码
    [Vega]
vega基因码
ensembl基因码
    [Ensembl]
基因家族(gene family)
refseq数据库代号

更多...

基因种类(locus_type)
基因名称状态(status)
location_sortable
同源基因名称(alias name)
基因名称批准使用时间(date_approved_reserved)
基因简称更名时间(date_symbol_changed)
基因名称更名时间(date_name_changed)
更新时间(date_modified)
ucsc码
ena
ccds数据码
uniprot数据码
pubmed代码
mgd码
rgd码
生命科学数据库(lsdb)
更新时间(date modified)
cosmic
mirbase
基因曾用简称(prev symbol)
基因曾用名称(prev name)
homeodb
cosmic
snornabase
bioparadigms slc
orphanet
假基因信息(pseudogeneorg)
horde id
merops
imgt
iuphar
kznf基因类别
mamit-trnadb
cd
LncRNA数据库
酶代码
中间纤维数据库

收起

基因染色体位置

基因染色体位置

11q23
基因染色体位置图

基因简述

基因简述

The protein encoded by this gene is part of the T-cell receptor/CD3 complex (TCR/CD3 complex) and is involved in T-cell development and signal transduction. The encoded membrane protein represents the delta subunit of the CD3 complex, and along with four other CD3 subunits, binds either TCR alpha/beta or TCR gamma/delta to form the TCR/CD3 complex on the surface of T-cells. Defects in this gene are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (SCIDBNK). Two transcript variants encoding different isoforms have been found for this gene. Other variants may also exist, but the full-length natures of their transcripts has yet to be defined. [provided by RefSeq, Feb 2009]

[中文简述(自动翻译):]  由该基因编码的蛋白质是T细胞受体/ CD3复合物（TCR / CD3复合）的一部分，参与T细胞发育和信号转导。所编码的膜蛋白代表的CD3复合物的增量亚基，并与其他四个CD3亚基一起结合任一的TCRα/β或TCR伽玛/三角形以形成T细胞表面上的TCR / CD3复合。在这个基因的缺陷是严重的联合免疫缺陷常染色体隐性遗传的T细胞阴性??/ B细胞阳性/ NK细胞阳性（SCIDBNK）的一个原因。已发现该基因编码不同亚型的两个转录变异体。其它变型也是可能存在，但它们的转录物的全长性质尚未被定义。 [由RefSeq的，2009年2月提供]

OMIM数据库中对CD3D基因的介绍     Wikipedia数据库中对CD3D基因的介绍

基因序列

基因序列

CD3D基因的碱基序列：[NCBI]

基因突变

基因突变

CD3D基因的碱基突变：           显示全部snp
rs486348       rs551134       rs1183409       rs1185771       rs1186453       rs2071381       rs2239695       rs2276423       rs2276424       rs2298822       rs3181259       rs3181261       rs3181262       rs3212267       rs3212268       rs3212270       rs7129048       rs7939548       rs7947185       rs12276558       rs12795615       rs28606580       rs36017260       rs45510201       rs45531936       rs45559236       rs45621535       rs56058731       rs56319346       rs60810919       rs61900915       rs67065773       rs68070310       rs73612298       rs74610174       rs75980154       rs76514660      
rs78306002       rs79667493       rs111033580       rs111033581       rs111684880       rs111841831       rs112575389       rs112970787       rs112978623       rs113037757       rs113271462       rs113912419       rs114445484       rs117930635       rs138416327       rs138432657       rs139047207       rs139083203       rs139096906       rs140349750       rs140991987       rs141588734       rs141902449       rs142119275       rs142464005       rs142873139       rs143063253       rs143606250       rs143616106       rs143990986       rs144040060       rs144504840       rs145293635       rs145946390       rs146407352       rs146465673       rs146652164       rs146997233       rs148629299       rs148789206       rs148892644       rs149264725       rs149418178       rs149624110       rs149712206       rs150184261       rs150376137       rs150570955       rs150657505       rs151183480       rs181713283       rs184751892       rs185486315       rs187207531       rs188033200       rs188697778       rs190000338       rs192887991       rs193284900       rs193922617       rs199553749       rs199969175       rs199972629       rs200015708       rs200037447       rs200089334       rs200132045       rs200235888       rs200238286       rs200260087       rs200272778       rs200326844       rs200390025       rs200390526       rs200520638       rs200731099       rs200847716       rs200910273       rs200942033       rs200977289       rs201006956       rs201021372       rs201126605       rs201266811       rs201271197       rs201276257       rs201297650       rs201299420       rs201527689       rs201535424       rs201539938       rs201650382       rs201721807       rs201810356       rs201961490       rs201994476       rs202075788       rs202077439       rs202080099       rs202149726       rs367800432       rs369069455       rs369351044       rs370352015       rs370928131       rs371909040       rs374700153       rs375444192       rs377380944       rs397764578       rs527584796       rs528174362       rs528486045       rs528728997       rs529225294       rs529398941       rs529884894       rs530435545       rs530500770       rs530917245       rs531304018       rs531705272       rs532141997       rs532696890       rs532780735       rs533066366       rs533211005       rs533613241       rs534530743       rs535635203       rs536903960       rs537028346       rs537089595       rs537955662       rs538018516       rs538224426       rs538288091       rs539213377       rs539797727       rs539847288       rs540530963       rs540819042       rs542148854       rs542708200       rs542784456       rs543267271       rs543328103       rs544276495       rs544325943       rs544518633       rs544781701       rs545408829       rs545468603       rs545678056       rs545920665       rs546624257       rs546981367       rs547025780       rs547344580       rs547884014       rs548307336       rs548365853       rs549491788       rs550460242       rs550523201       rs550573244       rs551736655       rs552808583       rs552911363       rs553214479       rs554138504       rs554347876       rs554887825       rs555604066       rs555740128       rs556823610       rs558013346       rs558078839       rs559053546       rs559165644       rs559442525       rs559713382       rs561152121       rs561557881       rs563103670       rs563164549       rs564092967       rs565301242       rs565377656       rs566748208       rs567299359       rs567861720       rs568150798       rs568215063       rs569045202       rs570295947       rs570360374       rs570795501       rs571561124       rs572315717       rs572431797       rs572955701       rs572979572       rs573276460       rs574213085       rs574464150       rs575478227       rs577531324       rs577595900       rs578129773       rs730880296       rs745794915       rs746058956       rs746486131       rs746667725       rs746752914       rs746931576       rs747445396       rs747613953       rs747808798       rs747917280       rs748106150       rs748182805       rs748640212       rs749221105       rs749243996       rs750023092       rs750243672       rs750458615       rs750498030       rs750542171       rs751568427       rs751718925       rs751800253       rs751892269       rs751905630       rs751973236       rs752168723       rs752718909       rs752902243       rs753003313       rs753045331       rs753332565       rs753689641       rs754368759       rs755215726       rs755235102       rs755253686       rs755381445       rs755401725       rs755697939       rs755751458       rs756347060       rs756599356       rs756611013       rs757050211       rs757319080       rs757787812       rs757790037       rs758585177       rs758632643       rs758839719       rs759200533       rs759324030       rs759638304       rs760316469       rs760334947       rs760666412       rs760813715       rs760993986       rs761459276       rs761840740       rs762023030       rs762031414       rs762228493       rs762324678       rs762366475       rs762667054       rs763052940       rs763077739       rs763545091       rs763565471       rs763754862       rs764062454       rs764338500       rs764487609       rs764502874       rs764812030       rs765242591       rs766136046       rs766581002       rs766635975       rs766922810       rs767834379       rs767884151       rs768234684       rs768322685       rs768551495       rs768641637       rs768851124       rs768957947       rs769427557       rs769547701       rs771000136       rs771195985       rs771585589       rs771637289       rs771969049       rs772480820       rs772563806       rs773317140       rs773449875       rs773529981       rs774034809       rs774851350       rs775134685       rs775164531       rs775386500       rs775464526       rs775582553       rs775855743       rs776557925       rs776683270       rs776882175       rs776993949       rs777087947       rs777386322       rs777432106       rs777623971       rs777709761       rs777721098       rs777921960       rs778457353       rs779053952       rs779545897       rs780577929       rs780662457       rs781135510       rs781413216       rs781522024       rs781625373      

基因表达

基因表达

CD3D基因在不同组织中的表达：    [UniProt]

基因在不同组织中的表达图

基因引物

基因引物

正向引物序列
正向引物Tm值
反向引物序列
反向引物Tm值
rank
AAGCTCTGTTGAGGAATGAC
58
TACTGAGCATCATCTCGATCTC
59
GCAAGTTCATTATCGAATGTGC
59
ATGACATCAGTGACAATGATGC
60
GTTCATTATCGAACTGCCGAC
60
AGCATCATCTCGATCTCGG
59
CATTTCCAGGAAGTGAGCC
59
GATGCTGGTATTGCAATTCAC
58
AGTTCATTATCGAACTGCCG
59
GCATCATCTCGATCTCGGA
59
CTCTGTTGAGGAATGACCAG
58
CTGTACTGAGCATCATCTCG
58
TTATCGAATGTGCCAGAGC
58
AGAGTGGCAATGACATCAG
58
TCATTTCCAGGAAGTGAGC
58
GATGCTGGTATTGCAATTCAC
58
TCATTTCCAGGAAGTGAGC
58
ATGCTGGTATTGCAATTCAC
57
CAAGTTCATTATCGAACTGCC
58
ATCATCTCGATCTCGGAGG
58

转录因子

转录因子

      尚未收录相关数据

基因本体信息

CD3D基因（以及对应的蛋白质）的细胞分布位置：

[UniProt]     [GenomeNet]

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • 溶酶体
  • 内涵体
  • 细胞核
  • 细胞质
  • 液泡
  • 细胞膜
  • 细胞外基质
  • 内质网
  • 线粒体
  • 高尔基体
  • 细胞骨架

CD3D基因的本体（GO）信息：

GO库代码
对应的蛋白质
来源代码
GO:0004888
E9PMT5(UniProtKB)
IEA
GO:0007166
E9PMT5(UniProtKB)
IEA
GO:0016021
E9PMT5(UniProtKB)
IEA
GO:0042101
E9PMT5(UniProtKB)
IEA
GO:0004888
H0YE18(UniProtKB)
IEA
GO:0007166
H0YE18(UniProtKB)
IEA
GO:0042101
H0YE18(UniProtKB)
IEA
GO:0003713
P04234(UniProtKB)
IDA
GO:0004888
P04234(UniProtKB)
IC
GO:0005737
P04234(UniProtKB)
NAS
GO:0005886
P04234(UniProtKB)
TAS
GO:0005886
P04234(UniProtKB)
TAS
GO:0005886
P04234(UniProtKB)
TAS
GO:0005886
P04234(UniProtKB)
TAS
GO:0005886
P04234(UniProtKB)
TAS
GO:0005886
P04234(UniProtKB)
TAS
GO:0005886
P04234(UniProtKB)
TAS
GO:0005886
P04234(UniProtKB)
TAS
GO:0005886
P04234(UniProtKB)
TAS
GO:0005886
P04234(UniProtKB)
TAS
GO:0005886
P04234(UniProtKB)
TAS
GO:0005886
P04234(UniProtKB)
TAS
GO:0005886
P04234(UniProtKB)
TAS
GO:0005886
P04234(UniProtKB)
TAS
GO:0005886
P04234(UniProtKB)
TAS
GO:0007166
P04234(UniProtKB)
IC
GO:0016021
P04234(UniProtKB)
IEA
GO:0030217
P04234(UniProtKB)
IDA
GO:0031295
P04234(UniProtKB)
TAS
GO:0042101
P04234(UniProtKB)
IDA
GO:0042101
P04234(UniProtKB)
NAS
GO:0042105
P04234(UniProtKB)
IEA
GO:0045059
P04234(UniProtKB)
ISS
GO:0045944
P04234(UniProtKB)
IDA
GO:0046982
P04234(UniProtKB)
IPI
GO:0050776
P04234(UniProtKB)
TAS
GO:0050852
P04234(UniProtKB)
TAS

基因相互作用关系

基因相互作用关系

基因与其他基因之间的相互作用关系图
序号 作用方式 资源库来源/分值 基因名称 基因名称

基因相关microRNA

基因相关microRNA

可能调控CD3D基因的相关microRNA：     

基因通路图

基因通路图

基因的通路属性图
通路基因列表

基因相关疾病

基因相关疾病

疾病名称 关系值 NofPmids NofSnps 来源
疾病名称 关系值 NofPmids NofSnps 来源
Severe Combined Immunodeficiency 0.123810118 6 0 BeFree_CTD_human_LHGDN
Biliary cirrhosis 0.12 1 0 CTD_human
Liver diseases 0.12 1 0 CTD_human
Dermatitis, Allergic Contact 0.12 1 0 CTD_human
Neurotoxicity Syndromes 0.12 1 0 CTD_human
Severe Combined Immunodeficiency, Autosomal Recessive, T Cell-Negative, B Cell-Positive, NK Cell-Negative 0.12 0 0 CTD_human
Severe Combined Immunodeficiency, Autosomal Recessive, T Cell Negative, B Cell Positive, NK Cell Positive 0.12 0 0 CTD_human
IMMUNODEFICIENCY 19 0.12 0 3 CLINVAR
Celiac Disease 0.002367032 1 0 GAD
Hay fever 0.002367032 1 0 GAD
Aplastic Anemia 0.000271442 1 0 BeFree
Malignant neoplasm of breast 0.000271442 1 0 BeFree
leukemia 0.000271442 1 0 BeFree
Lymphoma 0.000271442 1 0 BeFree
Lymphopenia 0.000271442 1 0 BeFree
Paraganglioma 0.000271442 1 0 BeFree
Breast Carcinoma 0.000271442 1 0 BeFree
Lymphoid depletion 0.000271442 1 0 BeFree
Inflammatory cardiomyopathy 0.000271442 1 0 BeFree

基因相关文献

基因相关文献

基因相关服务

基因相关服务

基因评论

基因评论

我要说两句
热门评论
还没有评论，赶快来抢沙发吧。

登陆

用户名:

密    码:

联系方式

山东省济南市 高新区 崇华路359号 三庆世纪财富中心C1115室

电话： 0531-88819269

E-mail: product@genelibs.com

微信公众号

扫一扫右方二维码，关注微信订阅号，实时查看信息，关注医学生物学动态。

版权所有 © 2016.Genelibs 济南弘晖生物技术有限公司 鲁ICP备13024435号-2