ASPN基因详情-基因数据库-基因云馆

ASPN(asporin) 转至新版数据库

基因简称(symbol)

ASPN [HGNC] [GeneCards] [NCBI]

基因种类(locus group)

protein-coding gene

同源简称(alias symbol)

FLJ20129|SLRR1C|PLAP1

基因家族代码(gene_family_id)

573 [HGNC] [GenScript]

omim代码

608135

entrez码

54829 [Vega]

vega基因码

OTTHUMG00000020227

ensembl基因码

ENSG00000106819 [Ensembl]

基因家族(gene family)

Small leucine-rich repeat proteoglycans

refseq数据库代号

NM_017680

更多...

基因种类(locus_type)

gene with protein product

基因名称状态(status)

Approved

location_sortable

09q22.31

同源基因名称(alias name)

asporin proteoglycan

基因名称批准使用时间(date_approved_reserved)

2001-03-21T00:00:00Z

基因简称更名时间(date_symbol_changed)

基因名称更名时间(date_name_changed)

2007-02-15T00:00:00Z

更新时间(date_modified)

2014-11-18T00:00:00Z

ucsc码

uc004ase.2

ena

AF316824

ccds数据码

uniprot数据码

Q9BXN1

pubmed代码

mgd码

MGI:1913945

rgd码

RGD:1549776

生命科学数据库(lsdb)

更新时间(date modified)

2014-11-18T00:00:00Z

cosmic

ASPN

mirbase

基因曾用简称(prev symbol)

基因曾用名称(prev name)

asporin (LRR class 1)

homeodb

cosmic

ASPN

snornabase

bioparadigms slc

orphanet

假基因信息(pseudogeneorg)

horde id

merops

imgt

iuphar

kznf基因类别

mamit-trnadb

cd

LncRNA数据库

酶代码

中间纤维数据库

收起

9q22.31

This gene encodes a cartilage extracellular protein that is member of the small leucine-rich proteoglycan family. The encoded protein may regulate chondrogenesis by inhibiting transforming growth factor-beta 1-induced gene expression in cartilage. This protein also binds collagen and calcium and may induce collagen mineralization. Polymorphisms in the aspartic acid repeat region of this gene are associated with a susceptibility to osteoarthritis, and also with intervertebral disc disease. Alternative splicing of this gene results in multiple transcript variants.[provided by RefSeq, Jul 2014]

[中文简述(自动翻译):] 该基因编码的软骨细胞外蛋白质，它是小富含亮氨酸的蛋白多糖家族的新成员。所编码的蛋白质可通过在软骨抑制转化生长因子-β1诱导的基因表达调节软骨形成。这种蛋白也结合胶原蛋白和钙，并可能诱发胶原矿化。在该基因的天冬氨酸重复区域多态性与易感性骨关节炎相关联，并且还与椎间盘疾病。在多个转录变异体这种基因的结果选择性剪接。[由RefSeq的，2014年7月提供]

OMIM数据库中对ASPN基因的介绍 Wikipedia数据库中对ASPN基因的介绍

ASPN基因的碱基序列：[NCBI]

ASPN基因的碱基突变：显示全部snp

rs8067 rs331377 rs1175604 rs1175605 rs1924243 rs1924244 rs2147058 rs2181712 rs3174352 rs3739606 rs3780348 rs3780349 rs4744132 rs4744133 rs4744134 rs7031567 rs7033979 rs7035992 rs7043809 rs7044810 rs7048953 rs7860774 rs7860786 rs7868013 rs7875681 rs10116241 rs10558102 rs10820978 rs10820979 rs10992347 rs10992348 rs10992349 rs10992350 rs11462797 rs11789163 rs11789759 rs11792295

rs12336884 rs12341093 rs12343820 rs12378430 rs13301537 rs17519719 rs17519922 rs17520068 rs17591776 rs17591958 rs17592026 rs17592132 rs34077247 rs35113181 rs35820236 rs41278695 rs41278697 rs41278699 rs41278701 rs58663005 rs58682047 rs60399788 rs61738525 rs71362392 rs72754403 rs72754404 rs72754408 rs72754410 rs72754411 rs72754412 rs72754415 rs73520549 rs73520554 rs73520572 rs74401108 rs74487467 rs75091981 rs75203987 rs75690917 rs75797835 rs75801664 rs76151617 rs76187584 rs76431873 rs76575509 rs76874569 rs76930379 rs76997970 rs77051528 rs77159326 rs77308866 rs77431848 rs77440622 rs77753461 rs77843240 rs77884224 rs78303623 rs78418761 rs78484808 rs78616007 rs78811128 rs79346350 rs79584548 rs79747237 rs79881653 rs80089545 rs111312597 rs111388208 rs111396526 rs111490633 rs111984514 rs112022626 rs112115019 rs112770807 rs112870954 rs113174148 rs113478791 rs113747060 rs113895406 rs113910366 rs114077163 rs114145311 rs114733129 rs114745964 rs116286022 rs116476899 rs117075404 rs117150430 rs117286664 rs117505250 rs117548148 rs117934413 rs117976877 rs118102781 rs138010536 rs138198730 rs138209327 rs138321845 rs138421880 rs138759568 rs138797216 rs138840946 rs139152691 rs139230827 rs139405419 rs139415247 rs139448501 rs139505803 rs139641085 rs139661085 rs139793402 rs140377846 rs140513533 rs140557213 rs140658451 rs140666433 rs140742110 rs141054431 rs141119348 rs141126230 rs141202754 rs141269345 rs141446497 rs141766771 rs141936069 rs142090803 rs142478869 rs142526348 rs142624887 rs142787785 rs142792490 rs142812734 rs142826539 rs143167391 rs143187778 rs143261961 rs143330695 rs143358512 rs143903433 rs144079283 rs144125864 rs144190760 rs144288385 rs144390523 rs144392142 rs144436559 rs144466034 rs144740230 rs144954352 rs145099290 rs145114693 rs145372239 rs145678731 rs145841803 rs145872406 rs145901771 rs146109583 rs146209094 rs146316968 rs146516859 rs146576866 rs146629520 rs146775001 rs146835430 rs147052913 rs147100147 rs147354437 rs147436402 rs147760530 rs147796836 rs148322348 rs148376603 rs148382623 rs148614825 rs148676537 rs148934175 rs149092012 rs149249512 rs149457593 rs149823108 rs150429702 rs150545989 rs150583184 rs150590397 rs150632303 rs150952503 rs151164130 rs151206801 rs151230261 rs151329560 rs180679658 rs180716523 rs180724191 rs181197547 rs181450272 rs181454183 rs181486140 rs181641171 rs181847998 rs181948035 rs182026820 rs182152955 rs182219513 rs182318739 rs182445972 rs182506847 rs182514480 rs182742696 rs182786867 rs182939657 rs183372524 rs183522122 rs183537083 rs183851943 rs184106864 rs184112662 rs184188976 rs184351371 rs184352910 rs184456569 rs184488278 rs184580891 rs185035822 rs185046151 rs185068312 rs185077359 rs185114758 rs185185928 rs185870267 rs185883796 rs185894511 rs186013243 rs186156128 rs186446386 rs186618152 rs186650062 rs186741299 rs186840940 rs186886229 rs187311836 rs187314779 rs187458284 rs187543149 rs187634009 rs187703018 rs187736833 rs187796617 rs187946775 rs188118313 rs188259362 rs188346772 rs188385289 rs188870598 rs189024647 rs189061549 rs189162586 rs189170743 rs189187040 rs189215625 rs189440515 rs189963773 rs190013109 rs190218000 rs190261925 rs190292439 rs190354401 rs190508890 rs190648506 rs190661521 rs190901784 rs191064326 rs191169746 rs191444932 rs191586578 rs191595798 rs191746622 rs191873815 rs191992911 rs192011995 rs192167042 rs192444442 rs192459615 rs192508172 rs192573246 rs192662297 rs192726784 rs192802924 rs192929126 rs193201527 rs199975126 rs200065132 rs200074927 rs200280971 rs200442197 rs200524940 rs201046344 rs201600758 rs201684741 rs201929283 rs201992263 rs367609513 rs367736538 rs368070065 rs368173888 rs369738156 rs369848705 rs370126754 rs370139381 rs370267148 rs370365676 rs370528303 rs371209367 rs371229890 rs371262202 rs371366367 rs371472912 rs371856281 rs371868297 rs372055606 rs372651365 rs373048043 rs373053528 rs373082643 rs373562694 rs373729044 rs374381931 rs374799886 rs374932025 rs375301019 rs375462737 rs375622311 rs375687115 rs377306545 rs377397087 rs377459728 rs377478533 rs397800469 rs527259219 rs527448999 rs527574701 rs527613378 rs527778922 rs528086365 rs528171748 rs528219656 rs528390803 rs528403723 rs528761910 rs528803668 rs528824831 rs528845070 rs528869959 rs528985139 rs529043714 rs529151763 rs529178271 rs529216521 rs529420954 rs530025596 rs530127671 rs530162702 rs530201050 rs530460818 rs530553720 rs530878074 rs530898549 rs530940224 rs530977854 rs531099058 rs531268036 rs531438683 rs531687712 rs531728796 rs531913837 rs532241723 rs532480691 rs532506296 rs532530458 rs532634002 rs532849935 rs532860050 rs532928908 rs532950974 rs532966151 rs532986769 rs533116047 rs533299412 rs533871594 rs533899324 rs533967243 rs533974561 rs534013453 rs534564720 rs534666124 rs534926508 rs535082388 rs535145508 rs535182947 rs535384377 rs535608705 rs535881047 rs535954380 rs535978251 rs536142089 rs536145168 rs536160985 rs536345493 rs536558247 rs536608475 rs536617670 rs536939419 rs537347263 rs537355334 rs537536594 rs537548767 rs537570021 rs537601237 rs537736130 rs537738056 rs537776898 rs537812573 rs537876324 rs537937983 rs537959897 rs538085106 rs538095237 rs538152275 rs538281678 rs538351639 rs538372241 rs538520130 rs538661719 rs539267191 rs539312673 rs539739979 rs540257473 rs540317798 rs540346394 rs540487202 rs540533031 rs540570182 rs540660576 rs540945551 rs541168851 rs541260748 rs541295958 rs541424402 rs541498040 rs541968247 rs541978076 rs541981215 rs542221018 rs542327992 rs542440734 rs542727647 rs542893639 rs542932420 rs543257008 rs543295156 rs543843099 rs543854910 rs544121863 rs544254458 rs544270137 rs544307065 rs544316113 rs544451853 rs544494085 rs544526633 rs544719480 rs545104184 rs545140869 rs545160847 rs545248282 rs545343521 rs546136510 rs546210515 rs546339582 rs546363028 rs546496164 rs546570470 rs546622987 rs547045166 rs547371611 rs547461276 rs547488832 rs547988055 rs548008613 rs548022201 rs548043517 rs548084538 rs548338874 rs548473663 rs548805780 rs548842147 rs548908796 rs549019763 rs549079352 rs549582043 rs549868322 rs549868351 rs550131881 rs550421079 rs550545153 rs550733321 rs550837742 rs550849805 rs550862117 rs550900781 rs550936794 rs551200941 rs551335108 rs551434297 rs551435065 rs551496779 rs551539972 rs551821367 rs551859773 rs551944513 rs552161042 rs552782069 rs552833849 rs552907784 rs553003035 rs553171986 rs553181303 rs553329477 rs553390769 rs553407905 rs553446144 rs553473156 rs553615770 rs553775730 rs553843783 rs554055222 rs554109785 rs554123422 rs554300209 rs554380817 rs554461715 rs554794264 rs555139999 rs555181456 rs555382805 rs555408168 rs555409767 rs555545259 rs555550074 rs555606688 rs555884210 rs556348505 rs556410578 rs556489994 rs556981685 rs557145091 rs557185742 rs557224445 rs557331353 rs557461078 rs557543739 rs557550719 rs557945470 rs557973515 rs558158524 rs558487443 rs558726949 rs558811849 rs559130639 rs559186024 rs559186217 rs559223233 rs559319681 rs559434189 rs559548331 rs559774888 rs559774957 rs559788040 rs559904844 rs560092234 rs560104273 rs560117738 rs560285981 rs560744552 rs560766654 rs560805195 rs560931002 rs561147099 rs561464739 rs561560053 rs561660969 rs561661230 rs561742601 rs561932265 rs562012429 rs562364640 rs562481872 rs562565663 rs562665574 rs562677082 rs562796251 rs563079316 rs563688907 rs563725660 rs563927019 rs564062032 rs564111691 rs564664039 rs564751587 rs564765249 rs564788450 rs565075616 rs565123246 rs565294663 rs565305357 rs565356062 rs565415372 rs565544837 rs565611402 rs565762158 rs565810963 rs566084628 rs566129015 rs566288248 rs566295296 rs566532018 rs566543148 rs566680100 rs566805012 rs566876195 rs567103957 rs567281555 rs567463701 rs567470397 rs567943276 rs568220547 rs568280168 rs568282046 rs568385785 rs568396923 rs568579139 rs569074049 rs569087727 rs569247498 rs569274142 rs569301849 rs569452516 rs569488274 rs569981850 rs570011459 rs570057198 rs570223257 rs570402350 rs570751813 rs570861796 rs570926731 rs570998233 rs571086216 rs571120771 rs571294138 rs571603521 rs571879697 rs571974578 rs571990398 rs572450488 rs572515878 rs572555754 rs572859146 rs572896765 rs572983269 rs573164091 rs573180187 rs573210549 rs573555783 rs573806552 rs573828761 rs573979918 rs573981048 rs574042918 rs574302537 rs574712042 rs574947226 rs574970813 rs575015780 rs575088533 rs575498230 rs575596806 rs575782676 rs575833950 rs575869820 rs575932430 rs576244486 rs576519750 rs576523596 rs576583001 rs576636353 rs576674218 rs576771960 rs576919751 rs576939423 rs576973569 rs577018333 rs577309318 rs577499813 rs577506317 rs577711873 rs577826216 rs577965995 rs578075952 rs745665400 rs745792146 rs745859210 rs745900506 rs745936135 rs745982674 rs746073101 rs746365449 rs746445338 rs747016115 rs747069469 rs747163071 rs747321863 rs747550942 rs747786934 rs747842140 rs748160430 rs748558453 rs748649282 rs748686870 rs748793521 rs748941760 rs749033215 rs749211954 rs749263045 rs749509390 rs749516419 rs749549480 rs749708861 rs750067800 rs750126730 rs750143544 rs750632561 rs750729556 rs750747080 rs751002441 rs751232189 rs751247045 rs751496863 rs751509078 rs751827826 rs751895655 rs752090969 rs752504095 rs752889006 rs753528217 rs753655881 rs753762024 rs753899547 rs754369253 rs754395031 rs754422619 rs754547694 rs754675611 rs754977945 rs755019248 rs755024270 rs755284490 rs755654979 rs755951081 rs756006046 rs756130551 rs756219105 rs756402866 rs756639577 rs756640697 rs756921551 rs757077133 rs757082299 rs757310340 rs757907813 rs757923286 rs758043075 rs758206044 rs758217255 rs758421977 rs758586100 rs758668356 rs758861627 rs758945968 rs759253599 rs759299671 rs759331739 rs759341355 rs759679562 rs759895992 rs760005228 rs760058506 rs760165232 rs760268622 rs760328846 rs760762922 rs760818914 rs761354426 rs761409866 rs761488471 rs761721603 rs761872466 rs761927381 rs762136374 rs762648168 rs762686926 rs762740047 rs763128075 rs763712969 rs763749029 rs763940804 rs763948305 rs763982158 rs764257845 rs765013550 rs765066997 rs765269212 rs765345253 rs765673267 rs765686923 rs765839278 rs765892728 rs765974567 rs766571754 rs766636733 rs766806570 rs766925567 rs767002052 rs767126722 rs767729849 rs768354906 rs768414075 rs768585989 rs768803902 rs769055070 rs769057452 rs769182352 rs769422692 rs769512341 rs769561020 rs769651044 rs770052707 rs770166448 rs770217740 rs770444535 rs770709159 rs770798965 rs771223552 rs771223864 rs771403311 rs771456947 rs771928226 rs772360082 rs772425741 rs772512883 rs772794867 rs772930777 rs772999588 rs773232869 rs773519082 rs773845974 rs774191998 rs774262129 rs774277824 rs774669492 rs774720272 rs774762901 rs774799220 rs774987564 rs775007730 rs775038925 rs775487189 rs775538414 rs776082307 rs776219974 rs776396635 rs776451841 rs776664075 rs776690193 rs776877419 rs776917242 rs777269498 rs777435658 rs777574002 rs777874790 rs778107184 rs778120761 rs778351517 rs778356943 rs778441508 rs778526424 rs778643481 rs778773420 rs778776532 rs779232502 rs779283967 rs779573188 rs779693811 rs779858427 rs780090505 rs780141507 rs780235435 rs780311826 rs780513757 rs781199371 rs781316611 rs781501185 rs781724741 rs113895406 rs532928908 rs539312673 rs553473156

ASPN基因在不同组织中的表达： [UniProt]

正向引物序列

正向引物Tm值

反向引物序列

反向引物Tm值

rank

GATCTGTTTCCAATGTGTCCA

59

GACTGAGGTCAAACCTAAATCTG

59

TAATAATGGGATAGAGCCAGGG

59

GGAAGATTATCTTTAGGAACTGAGG

59

AATAATGGGATAGAGCCAGGG

59

GGAAGATTATCTTTAGGAACTGAGG

59

ACAAAGAACTACAAAGGCTGG

59

CACGTGGTATGTTAGCAAGAC

59

AAGAACTACAAAGGCTGGG

57

TCACACGTGGTATGTTAGC

58

ATAATGGGATAGAGCCAGGG

59

GGAAGATTATCTTTAGGAACTGAGG

59

TACAAAGAACTACAAAGGCTGG

59

ACGTGGTATGTTAGCAAGAC

58

TTGATCTGTTTCCAATGTGTCC

59

CTGAGGTCAAACCTAAATCTGAG

59

TGATCTGTTTCCAATGTGTCC

59

ACTGAGGTCAAACCTAAATCTG

58

尚未收录相关数据

ASPN基因（以及对应的蛋白质）的细胞分布位置：

[UniProt] [GenomeNet]

溶酶体
内涵体
细胞核
细胞质
液泡
细胞膜
细胞外基质
内质网
线粒体
高尔基体
细胞骨架

ASPN基因的本体（GO）信息：

GO库代码

对应的蛋白质

来源代码

GO:0005509

Q5TBF2(UniProtKB)

IEA

GO:0005518

Q5TBF2(UniProtKB)

IEA

GO:0004860

Q9BXN1(UniProtKB)

IBA

GO:0005509

Q9BXN1(UniProtKB)

IDA

GO:0005518

Q9BXN1(UniProtKB)

IEA

GO:0005578

Q9BXN1(UniProtKB)

IDA

GO:0005737

Q9BXN1(UniProtKB)

IBA

GO:0006469

Q9BXN1(UniProtKB)

IBA

GO:0019221

Q9BXN1(UniProtKB)

IBA

GO:0030282

Q9BXN1(UniProtKB)

IDA

GO:0030512

Q9BXN1(UniProtKB)

IDA

GO:0046426

Q9BXN1(UniProtKB)

IBA

GO:0070171

Q9BXN1(UniProtKB)

ISS

GO:0031012

Q9BXN1(UniProtKB)

IDA

序号	作用方式	资源库来源/分值	基因名称	基因名称

可能调控ASPN基因的相关microRNA：

hsa-miR-124 hsa-miR-26b hsa-miR-335 hsa-miR-101 hsa-miR-21*

通路基因列表

疾病名称

关系值

NofPmids

NofSnps

来源

疾病名称	关系值	NofPmids	NofSnps	来源
Degenerative polyarthritis	0.156891145	27	1	BeFree_CTD_human_GAD_LHGDN
Keloid	0.12	1	0	CTD_human
Intervertebral disc disorder	0.12	0	0	CTD_human
Osteoarthritis, Knee	0.011996981	11	0	BeFree_GAD_LHGDN
Ankylosing spondylitis	0.002638474	1	0	BeFree_GAD
Osteochondritis	0.002367032	1	0	GAD
Osteoarthritis of hip	0.000814326	3	0	BeFree
Malignant neoplasm of stomach	0.000542884	2	0	BeFree
Carcinogenesis	0.000542884	2	0	BeFree
Stomach Carcinoma	0.000542884	2	0	BeFree
Rheumatoid Arthritis	0.000271442	1	0	BeFree
Hip Dislocation, Congenital	0.000271442	1	0	BeFree
Arthropathy	0.000271442	1	0	BeFree
Neoplasm Metastasis	0.000271442	1	0	BeFree
Congenital torticollis	0.000271442	1	0	BeFree
Intervertebral Disc Degeneration	0.000271442	1	0	BeFree
Lumbar disc disease	0.000271442	1	0	BeFree
Degeneration of lumbar intervertebral disc	0.000271442	1	0	BeFree
Fibromatosis colli	0.000271442	1	0	BeFree
Cancer Cell Growth	0.000271442	1	0	BeFree