PPP1R15A(protein phosphatase 1, regulatory subunit 15A) 转至新版数据库

基因基本信息

基因基本信息

基因简称(symbol)
    [HGNC]     [GeneCards]     [NCBI]
基因种类(locus group)
同源简称(alias symbol)
基因家族代码(gene_family_id)
    [HGNC]     [GenScript]
omim代码
entrez码
    [Vega]
vega基因码
ensembl基因码
    [Ensembl]
基因家族(gene family)
refseq数据库代号

更多...

基因种类(locus_type)
基因名称状态(status)
location_sortable
同源基因名称(alias name)
基因名称批准使用时间(date_approved_reserved)
基因简称更名时间(date_symbol_changed)
基因名称更名时间(date_name_changed)
更新时间(date_modified)
ucsc码
ena
ccds数据码
uniprot数据码
pubmed代码
mgd码
rgd码
生命科学数据库(lsdb)
更新时间(date modified)
cosmic
mirbase
基因曾用简称(prev symbol)
基因曾用名称(prev name)
homeodb
cosmic
snornabase
bioparadigms slc
orphanet
假基因信息(pseudogeneorg)
horde id
merops
imgt
iuphar
kznf基因类别
mamit-trnadb
cd
LncRNA数据库
酶代码
中间纤维数据库

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基因染色体位置

基因染色体位置

19q13.2
基因染色体位置图

基因简述

基因简述

This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The induction of this gene by ionizing radiation occurs in certain cell lines regardless of p53 status, and its protein response is correlated with apoptosis following ionizing radiation. [provided by RefSeq, Jul 2008]

[中文简述(自动翻译):]  此基因是一组基因，其转录水平增加以下压力的生长停滞条件和与DNA损伤剂治疗中的一员。该基因通过电离辐射诱导发生在某些细胞系的无论p53状态，并且其蛋白质的反应与细胞凋亡的电离辐射相关。 [由RefSeq的，2008年7月提供]

OMIM数据库中对PPP1R15A基因的介绍     Wikipedia数据库中对PPP1R15A基因的介绍

基因序列

基因序列

PPP1R15A基因的碱基序列：[NCBI]

基因突变

基因突变

PPP1R15A基因的碱基突变：           显示全部snp
rs192014448       rs529070146       rs542081897       rs565219973       rs524       rs527       rs500079       rs540039       rs556052       rs557806       rs564196       rs594597       rs594600       rs595051       rs595474       rs595516       rs595982       rs610308       rs611251       rs626140       rs626974       rs638050       rs687384       rs688644       rs837608       rs837609       rs837610       rs837611       rs1050166       rs2270946       rs3057861       rs3786734       rs7260416       rs11541191       rs11541192       rs17272694       rs17554987      
rs34457521       rs34899467       rs35007147       rs35023389       rs35087747       rs45533432       rs56697799       rs57362374       rs60927724       rs62127977       rs62127978       rs73589816       rs73589818       rs73942337       rs74727194       rs74738147       rs74780148       rs74794385       rs75202631       rs77377218       rs77919834       rs79748510       rs80010485       rs80213386       rs111349101       rs111401415       rs111550347       rs111963761       rs112209279       rs112367256       rs112537610       rs113082645       rs113181686       rs113190996       rs113359164       rs113445675       rs113525688       rs113985313       rs114326964       rs114477690       rs116429715       rs116430909       rs137978264       rs138534953       rs138580661       rs138608463       rs138912909       rs138968424       rs139425008       rs139708522       rs140767023       rs140853052       rs140859570       rs140904663       rs141370460       rs141730546       rs142378074       rs142686151       rs142855954       rs143444771       rs143549142       rs144277804       rs144400267       rs144473195       rs144567890       rs144588770       rs144621980       rs144656026       rs144695136       rs144725427       rs144731567       rs144761982       rs144876462       rs145400447       rs146194308       rs146665963       rs146703223       rs146849578       rs147205273       rs147256383       rs147687948       rs147814056       rs147982816       rs148034650       rs148069203       rs148460066       rs148913925       rs149431519       rs149496861       rs149778673       rs149991228       rs150011740       rs150728200       rs151082769       rs180751040       rs181366844       rs181843137       rs182628860       rs183255104       rs183624468       rs184379585       rs184622024       rs184810900       rs185897412       rs186203078       rs186438232       rs187493181       rs187780713       rs188089984       rs188498603       rs189157748       rs189453385       rs190962820       rs190969435       rs191743959       rs192997367       rs199543396       rs199878289       rs199891815       rs199990581       rs200237494       rs200500833       rs200581070       rs200976816       rs200986283       rs201012471       rs201073468       rs201162503       rs201219958       rs201262597       rs201432621       rs201458751       rs201905583       rs201957583       rs202096859       rs202101320       rs202191597       rs367785147       rs368067897       rs368302218       rs368379467       rs368648855       rs369203609       rs369701184       rs369896585       rs370100459       rs370969118       rs371012590       rs371024875       rs371034417       rs371089180       rs371401814       rs371690928       rs371798766       rs372017913       rs372040847       rs372171559       rs372192564       rs372233957       rs373036822       rs373159566       rs373166701       rs373338552       rs373351648       rs373762322       rs374067843       rs374482307       rs374535887       rs375049799       rs375361440       rs375792716       rs375871401       rs376198987       rs376245715       rs376576127       rs377143682       rs377303017       rs377547229       rs398034914       rs527736852       rs527803689       rs528417901       rs529516931       rs529573826       rs529994897       rs530071291       rs530377587       rs530647865       rs532407978       rs532472217       rs532521288       rs532963227       rs533003222       rs533628681       rs533691597       rs533751927       rs533986662       rs534167102       rs535002242       rs535910031       rs536099119       rs536325560       rs536484878       rs536768369       rs536831168       rs537689281       rs538298636       rs538712004       rs539319692       rs540303499       rs540438539       rs540566506       rs541650815       rs541820334       rs541870771       rs542080659       rs542853891       rs543801585       rs544146859       rs545597306       rs545770643       rs547124401       rs548313458       rs548393011       rs550110278       rs550999038       rs552189317       rs552207545       rs553679628       rs554509635       rs554889185       rs556469274       rs556876971       rs557873289       rs558669965       rs558711904       rs558715376       rs560070795       rs560126141       rs560131549       rs560195365       rs560256516       rs561018347       rs561497593       rs562024289       rs562789058       rs563384060       rs563814474       rs564057305       rs564092336       rs565027024       rs566352513       rs566687328       rs566823726       rs566890925       rs567430726       rs567547680       rs568042227       rs569130500       rs569259259       rs570651435       rs570683004       rs571123568       rs572964271       rs572978269       rs574085051       rs574649178       rs575250363       rs575290178       rs577024195       rs577145463       rs577604081       rs745307025       rs745389303       rs745498884       rs745605469       rs745698127       rs745716495       rs745899453       rs745991371       rs746056267       rs746180993       rs746254526       rs746351950       rs746479005       rs746564900       rs746721951       rs746786955       rs746821743       rs746891790       rs746960507       rs747064785       rs747169592       rs747248462       rs747393431       rs747457646       rs747561869       rs747908713       rs748198214       rs748251385       rs748305940       rs748472912       rs748562803       rs748682175       rs748786068       rs749055306       rs749134427       rs749134444       rs749232698       rs749342299       rs749343608       rs749431534       rs749479704       rs749538089       rs749614844       rs749999960       rs750080475       rs750120273       rs750340990       rs750372358       rs750562426       rs750620616       rs750670220       rs750807545       rs750857089       rs750885937       rs751080787       rs751088346       rs751320817       rs751412724       rs751678533       rs751881103       rs752038705       rs752039069       rs752047042       rs752206028       rs752211715       rs752267811       rs752301235       rs752332454       rs752488798       rs752606866       rs752609497       rs752942887       rs752965816       rs753035746       rs753063814       rs753264539       rs753384204       rs753437738       rs753561915       rs753755934       rs753757835       rs754130334       rs754168098       rs754199338       rs754378637       rs754521332       rs754628643       rs754646874       rs754748262       rs754761243       rs754854098       rs755358847       rs755456726       rs755546126       rs755730793       rs755786656       rs755872668       rs756002060       rs756028926       rs756083080       rs756283354       rs756385137       rs756444344       rs756508458       rs756585037       rs756641166       rs756791102       rs756931461       rs757385027       rs757438814       rs757527468       rs757760679       rs757853624       rs757993474       rs758001662       rs758099641       rs758303406       rs758385881       rs758409379       rs758704553       rs758780762       rs758846641       rs758973673       rs759199218       rs759350145       rs759389943       rs759405447       rs759511503       rs759555858       rs759560350       rs759645779       rs759963976       rs760073575       rs760287672       rs760341530       rs760371750       rs760431160       rs760547767       rs760685236       rs760686351       rs760966697       rs760976406       rs761091479       rs761254605       rs761254662       rs761342397       rs761391876       rs761422376       rs761450142       rs761644106       rs761692417       rs761985375       rs762271058       rs762302741       rs762406895       rs762682250       rs762769609       rs762837215       rs762936629       rs762947886       rs763051525       rs763052879       rs763202804       rs763211405       rs763586619       rs763654701       rs763781265       rs763814571       rs763967808       rs763974981       rs764028120       rs764179438       rs764242076       rs764348391       rs764387649       rs764437380       rs764639487       rs764652406       rs764798313       rs764936828       rs764939326       rs765307835       rs765515023       rs765710268       rs765961040       rs766014892       rs766389920       rs766473236       rs766671787       rs766823908       rs766877382       rs767162394       rs767205742       rs767212164       rs767241754       rs767411145       rs767574300       rs767605587       rs767768568       rs767917201       rs767921711       rs767948478       rs767983554       rs768010525       rs768034833       rs768255399       rs768483325       rs768516242       rs768598345       rs768664167       rs768756506       rs768871719       rs768915207       rs769022111       rs769169927       rs769270279       rs769283098       rs769325327       rs769390105       rs769579706       rs769597605       rs769644424       rs769690304       rs769967230       rs769979456       rs770019481       rs770295271       rs770470638       rs770481866       rs770723222       rs770878530       rs770966592       rs771142197       rs771308583       rs771518130       rs771676165       rs771916648       rs771964492       rs772078537       rs772092347       rs772237829       rs772273966       rs772307871       rs772344141       rs772407341       rs772579750       rs772671707       rs772845675       rs772939947       rs773032437       rs773313018       rs773446345       rs773483951       rs773610977       rs773653661       rs773697724       rs773886388       rs773973487       rs774438286       rs774457865       rs774480066       rs774585965       rs774754970       rs774919285       rs774945114       rs775033354       rs775150021       rs775218534       rs775229479       rs775316026       rs775373103       rs775529077       rs775690405       rs775691605       rs775776988       rs776266319       rs776273456       rs776355420       rs776464676       rs776893170       rs776893878       rs776947560       rs777029577       rs777037170       rs777100478       rs777236234       rs777515960       rs777713643       rs777864167       rs777970448       rs778047173       rs778110969       rs778165768       rs778539827       rs778608947       rs778609437       rs778644567       rs778655750       rs778736029       rs778754822       rs778824701       rs778840608       rs779098200       rs779422193       rs779475446       rs779679739       rs779896799       rs779991472       rs780153854       rs780174342       rs780479208       rs780551987       rs780640085       rs780750361       rs780930149       rs780935782       rs780995157       rs781132784       rs781170903       rs781175895       rs781458075       rs781681826      

基因表达

基因表达

PPP1R15A基因在不同组织中的表达：    [UniProt]

基因在不同组织中的表达图

基因引物

基因引物

正向引物序列
正向引物Tm值
反向引物序列
反向引物Tm值
rank
CTAAAGGCCAGAAAGGTGC
59
TAAAGGTGGGTTCCTGAGG
59
GAGGACAGTGATACAGGATCAG
60
GTGTGGAAGCAGAAGTCTC
58
CTAAAGGCCAGAAAGGTGC
59
CTAAAGGTGGGTTCCTGAG
57
CTAAAGGCCAGAAAGGTGC
59
CTAAAGGTGGGTTCCTGAGG
60
GGAAGAGGGAGAAGCTGAG
59
GGACTTCAAGAAGACACCTG
58
ATGAGGACAGTGATACAGGA
58
GTGGAAGCAGAAGTCTCAG
58

转录因子

转录因子

      尚未收录相关数据

基因本体信息

PPP1R15A基因（以及对应的蛋白质）的细胞分布位置：

[UniProt]     [GenomeNet]

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • 溶酶体
  • 内涵体
  • 细胞核
  • 细胞质
  • 液泡
  • 细胞膜
  • 细胞外基质
  • 内质网
  • 线粒体
  • 高尔基体
  • 细胞骨架

PPP1R15A基因的本体（GO）信息：

GO库代码
对应的蛋白质
来源代码
GO:0000164
O75807(UniProtKB)
IDA
GO:0000164
O75807(UniProtKB)
IDA
GO:0001934
O75807(UniProtKB)
IEA
GO:0005515
O75807(UniProtKB)
IPI
GO:0005515
O75807(UniProtKB)
IPI
GO:0005737
O75807(UniProtKB)
IDA
GO:0005739
O75807(UniProtKB)
IDA
GO:0005741
O75807(UniProtKB)
IEA
GO:0005783
O75807(UniProtKB)
IDA
GO:0005783
O75807(UniProtKB)
IDA
GO:0005789
O75807(UniProtKB)
NAS
GO:0005794
O75807(UniProtKB)
IDA
GO:0005829
O75807(UniProtKB)
TAS
GO:0005829
O75807(UniProtKB)
TAS
GO:0006915
O75807(UniProtKB)
TAS
GO:0006974
O75807(UniProtKB)
TAS
GO:0007050
O75807(UniProtKB)
TAS
GO:0007568
O75807(UniProtKB)
IEA
GO:0008157
O75807(UniProtKB)
IDA
GO:0008157
O75807(UniProtKB)
IPI
GO:0008157
O75807(UniProtKB)
IPI
GO:0008285
O75807(UniProtKB)
IEA
GO:0008599
O75807(UniProtKB)
IC
GO:0008599
O75807(UniProtKB)
IC
GO:0010801
O75807(UniProtKB)
IEA
GO:0010955
O75807(UniProtKB)
IEA
GO:0016020
O75807(UniProtKB)
IDA
GO:0019901
O75807(UniProtKB)
IPI
GO:0030968
O75807(UniProtKB)
IEA
GO:0030968
O75807(UniProtKB)
IEA
GO:0032058
O75807(UniProtKB)
IC
GO:0032515
O75807(UniProtKB)
IDA
GO:0032516
O75807(UniProtKB)
IDA
GO:0034644
O75807(UniProtKB)
IEA
GO:0034976
O75807(UniProtKB)
IDA
GO:0035308
O75807(UniProtKB)
IDA
GO:0035690
O75807(UniProtKB)
IEA
GO:0035902
O75807(UniProtKB)
IEA
GO:0036496
O75807(UniProtKB)
IDA
GO:0042220
O75807(UniProtKB)
IEA
GO:0043065
O75807(UniProtKB)
IEA
GO:0045765
O75807(UniProtKB)
IEA
GO:0060548
O75807(UniProtKB)
IEA
GO:0060734
O75807(UniProtKB)
IEA
GO:0070059
O75807(UniProtKB)
TAS
GO:0070262
O75807(UniProtKB)
IEA
GO:0070972
O75807(UniProtKB)
IMP
GO:0071236
O75807(UniProtKB)
IEA
GO:0071322
O75807(UniProtKB)
IEA
GO:0071862
O75807(UniProtKB)
IC
GO:0072703
O75807(UniProtKB)
IEA
GO:0072732
O75807(UniProtKB)
IEA
GO:0090648
O75807(UniProtKB)
IEA
GO:0090650
O75807(UniProtKB)
IEA
GO:1902310
O75807(UniProtKB)
IDA
GO:1902310
O75807(UniProtKB)
IDA
GO:1902310
O75807(UniProtKB)
IDA
GO:1903898
O75807(UniProtKB)
TAS
GO:1903912
O75807(UniProtKB)
IEA
GO:1903917
O75807(UniProtKB)
IDA
GO:1903917
O75807(UniProtKB)
TAS
GO:1904308
O75807(UniProtKB)
IEA
GO:1904310
O75807(UniProtKB)
IEA
GO:1904312
O75807(UniProtKB)
IEA
GO:1904314
O75807(UniProtKB)
IEA
GO:1990441
O75807(UniProtKB)
IEA

基因相互作用关系

基因相互作用关系

基因与其他基因之间的相互作用关系图
序号 作用方式 资源库来源/分值 基因名称 基因名称

基因相关microRNA

基因相关microRNA

可能调控PPP1R15A基因的相关microRNA：     

基因通路图

基因通路图

基因的通路属性图
通路基因列表

基因相关疾病

基因相关疾病

疾病名称 关系值 NofPmids NofSnps 来源
疾病名称 关系值 NofPmids NofSnps 来源
Brain Ischemia 0.08 1 0 RGD
Transient Ischemic Attack 0.08 1 0 RGD
Pathological accumulation of air in tissues 0.08 1 0 RGD
Cerebrovascular accident 0.08 1 0 RGD
melanoma 0.003267234 3 0 BeFree_LHGDN
Tuberous Sclerosis 0.00272435 1 0 LHGDN
Kidney Failure, Chronic 0.002367032 1 1 GAD
Ischemia 0.000814326 3 0 BeFree
Cardiac Arrest 0.000542884 2 0 BeFree
Herpes Simplex Infections 0.000542884 2 0 BeFree
Alzheimer's Disease 0.000271442 1 0 BeFree
Amyotrophic Lateral Sclerosis 0.000271442 1 0 BeFree
Colitis 0.000271442 1 0 BeFree
Coronary Arteriosclerosis 0.000271442 1 0 BeFree
Glioma 0.000271442 1 0 BeFree
Herpes NOS 0.000271442 1 0 BeFree
Transient ischemia 0.000271442 1 0 BeFree
Multiple Myeloma 0.000271442 1 0 BeFree
Ovarian Carcinoma 0.000271442 1 0 BeFree
Myocardial Ischemia 0.000271442 1 0 BeFree
Tumor necrosis 0.000271442 1 0 BeFree
Carcinogenesis 0.000271442 1 0 BeFree
Malignant Pleural Mesothelioma 0.000271442 1 0 BeFree
Malignant neoplasm of ovary 0.000271442 1 0 BeFree

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