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The WNT gene family consists of structurally related genes that encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. Study of its expression in the teratocarcinoma cell line NT2 suggests that it may be implicated in the early process of neuronal differentiation of NT2 cells induced by retinoic acid. This gene is clustered with WNT3, another family member, in the chromosome 17q21 region. [provided by RefSeq, Jul 2008]
[中文简述(自动翻译):]  Wnt信号基因家族由编码分泌信号蛋白结构相关的基因。这些蛋白质有牵连肿瘤发生并在几个发育过程,包括胚胎发育过程中细胞命运和图案化的调节。此基因是WNT基因家族的一个成员。研究其在畸胎瘤细胞系NT2表现表明,它可能通过维甲酸诱导NT2细胞的神经元分化的早期过程中受到牵连。该基因簇与WNT3,其他家庭成员,在染色体17q21上的区域。 [由RefSeq的,2008年7月提供]
WNT9B基因(以及对应的蛋白质)的细胞分布位置:
WNT9B基因的本体(GO)信息:
疾病名称 | 关系值 | NofPmids | NofSnps | 来源 |
Cleft Lip | 0.007372538 | 4 | 0 | BeFree_GAD |
Cleft Palate | 0.007372538 | 4 | 0 | BeFree_GAD |
Dental Enamel Hypoplasia | 0.002367032 | 1 | 0 | GAD |
Tobacco Use Disorder | 0.002367032 | 1 | 0 | GAD |
Rokitansky Kuster Hauser syndrome | 0.000542884 | 2 | 0 | BeFree |
Bladder Exstrophy | 0.000271442 | 1 | 0 | BeFree |
Virus Diseases | 0.000271442 | 1 | 0 | BeFree |
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