TFAP2C(transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)) 转至新版数据库

基因基本信息

基因基本信息

基因简称(symbol)
    [HGNC]     [GeneCards]     [NCBI]
基因种类(locus group)
同源简称(alias symbol)
基因家族代码(gene_family_id)
    [HGNC]     [GenScript]
omim代码
entrez码
    [Vega]
vega基因码
ensembl基因码
    [Ensembl]
基因家族(gene family)
refseq数据库代号

更多...

基因种类(locus_type)
基因名称状态(status)
location_sortable
同源基因名称(alias name)
基因名称批准使用时间(date_approved_reserved)
基因简称更名时间(date_symbol_changed)
基因名称更名时间(date_name_changed)
更新时间(date_modified)
ucsc码
ena
ccds数据码
uniprot数据码
pubmed代码
mgd码
rgd码
生命科学数据库(lsdb)
更新时间(date modified)
cosmic
mirbase
基因曾用简称(prev symbol)
基因曾用名称(prev name)
homeodb
cosmic
snornabase
bioparadigms slc
orphanet
假基因信息(pseudogeneorg)
horde id
merops
imgt
iuphar
kznf基因类别
mamit-trnadb
cd
LncRNA数据库
酶代码
中间纤维数据库

收起

基因染色体位置

基因染色体位置

20q13.2
基因染色体位置图

基因简述

基因简述

The protein encoded by this gene is a sequence-specific DNA-binding transcription factor involved in the activation of several developmental genes. The encoded protein can act as either a homodimer or heterodimer with other family members and is induced during retinoic acid-mediated differentiation. It plays a role in the development of the eyes, face, body wall, limbs, and neural tube. [provided by RefSeq, Jul 2008]

[中文简述(自动翻译):]  由该基因编码的蛋白质是参与几种发育基因的活化序列特异性DNA结合的转录因子。所编码的蛋白质可以作为两种同二聚体或异二聚体与其他家庭成员和视黄酸介导的分化期间被诱导。它在眼睛，面部，体壁，四肢和神经管发育的作用。 [由RefSeq的，2008年7月提供]

OMIM数据库中对TFAP2C基因的介绍     Wikipedia数据库中对TFAP2C基因的介绍

基因序列

基因序列

TFAP2C基因的碱基序列：[NCBI]

基因突变

基因突变

TFAP2C基因的碱基突变：           显示全部snp
rs1720       rs1475232       rs3787377       rs3827102       rs6025019       rs6025020       rs6025024       rs6092335       rs6099216       rs6513245       rs7268592       rs7271133       rs10625200       rs10626060       rs11454490       rs11908195       rs34060732       rs35023929       rs35789407       rs41307195       rs58605358       rs62208554       rs62208555       rs62208556       rs62208557       rs66891256       rs73165730       rs73913988       rs74181066       rs74181067       rs74337668       rs74478756       rs74497783       rs75091033       rs75166173       rs76263419       rs76833551      
rs78683858       rs79298586       rs79464696       rs79493073       rs79656554       rs79759188       rs80037172       rs80186009       rs111436406       rs112123037       rs112295160       rs112906072       rs112950894       rs113294812       rs113541999       rs113970055       rs114247412       rs114326725       rs114697045       rs115244423       rs115561987       rs116340179       rs118107225       rs138048707       rs138104861       rs138750457       rs138840509       rs139203976       rs139254561       rs139434386       rs140351622       rs140595340       rs140675668       rs140905864       rs141841777       rs141919939       rs142582019       rs142676160       rs142822544       rs143521494       rs143555025       rs143623320       rs144019270       rs144807818       rs145383981       rs145413166       rs145476817       rs145482242       rs146275217       rs146454069       rs146779844       rs146916115       rs147055158       rs147379691       rs147506390       rs147962852       rs148033995       rs148118000       rs148191643       rs148562100       rs148998401       rs149218262       rs149531495       rs149662940       rs150059207       rs150169883       rs150187185       rs150697977       rs151166545       rs181043093       rs181728691       rs181795695       rs181982514       rs182214032       rs182399348       rs182584272       rs182731521       rs182823005       rs182844622       rs183059211       rs183578824       rs183636773       rs183711473       rs184044761       rs184394344       rs184431869       rs184564363       rs185256295       rs185931553       rs186082947       rs186141517       rs186503162       rs186629660       rs187076642       rs187314201       rs187927430       rs187955236       rs188018970       rs188736198       rs188914795       rs188928431       rs189017094       rs189476265       rs189779159       rs190079149       rs190125645       rs190394423       rs190563250       rs190660001       rs191450743       rs191833061       rs192203017       rs192275203       rs192434905       rs192490598       rs192945891       rs192966534       rs199651063       rs199796283       rs200017220       rs200359056       rs200592188       rs200833204       rs200945064       rs201445633       rs201529764       rs201679767       rs202233465       rs368296119       rs368445146       rs368702281       rs368851871       rs368862120       rs369245697       rs369657489       rs369684214       rs369702938       rs369867274       rs369895748       rs370275218       rs370592057       rs371168193       rs371445486       rs371578993       rs371845292       rs372001250       rs372272136       rs372281758       rs372289602       rs373162826       rs373419629       rs373593640       rs374078533       rs374277015       rs374635110       rs375002279       rs375252015       rs375391110       rs375808345       rs376628585       rs377315978       rs377446365       rs377580128       rs527485582       rs527573283       rs528040391       rs528042448       rs528347000       rs528511935       rs528641187       rs528685340       rs528787965       rs529055471       rs529085815       rs529704470       rs529753018       rs530325477       rs530493365       rs531232024       rs531826187       rs531837063       rs531874315       rs531890882       rs532632092       rs532923588       rs533126613       rs533285478       rs533335892       rs533446152       rs533979549       rs534106984       rs534319781       rs534401964       rs535236198       rs535327824       rs535420378       rs535492916       rs535692605       rs535739475       rs536116894       rs536336610       rs536337577       rs536380535       rs536744789       rs537107217       rs537184936       rs537341326       rs537780535       rs537987208       rs538057418       rs538068999       rs538776730       rs538786666       rs539461033       rs539478139       rs539665707       rs539712483       rs540246227       rs540444027       rs540558370       rs540753024       rs541491852       rs541579615       rs541607685       rs541873256       rs542186140       rs542345946       rs542381202       rs542465228       rs542568260       rs543134927       rs543945245       rs544140373       rs544181436       rs544544161       rs544820793       rs544927901       rs545248731       rs545332566       rs546223833       rs546248486       rs546673064       rs546718748       rs546931242       rs547384561       rs547593720       rs547641702       rs547685125       rs548468806       rs548617048       rs549054266       rs549578507       rs550291691       rs550346669       rs550377636       rs550902407       rs550944977       rs550945288       rs550945544       rs551381615       rs551847068       rs551986535       rs552057520       rs552072802       rs552402336       rs552526297       rs552658671       rs552746501       rs553016820       rs553053777       rs553057977       rs553725054       rs553939438       rs554117564       rs554205076       rs554531143       rs554597999       rs555013417       rs555033312       rs555038877       rs555323843       rs555662440       rs555789543       rs555988383       rs555992781       rs556637563       rs556695054       rs556780851       rs556818666       rs557047894       rs557389234       rs557429745       rs558168001       rs558182717       rs558498543       rs558506302       rs558638914       rs558740522       rs559154773       rs559156622       rs559242835       rs559942742       rs560308805       rs560333842       rs560351260       rs560499663       rs560715648       rs560897695       rs560906553       rs560967538       rs560981604       rs561170352       rs561241360       rs561523650       rs561823245       rs562247731       rs562533639       rs562604858       rs562889357       rs563528822       rs563631626       rs563664321       rs564233612       rs564685726       rs564772219       rs564859716       rs564923304       rs565141146       rs565156856       rs565269985       rs565327009       rs565854939       rs566326142       rs566491833       rs566573447       rs566586672       rs567404853       rs567511310       rs567745139       rs567964940       rs568220535       rs568306342       rs568344053       rs568914637       rs568990583       rs569781334       rs569868407       rs569948552       rs570117977       rs570186887       rs570708023       rs570773857       rs570900237       rs570937417       rs570976806       rs571269688       rs571501361       rs571545943       rs571921612       rs571995378       rs572444195       rs572444321       rs572675016       rs572760677       rs572779329       rs572987314       rs573472041       rs573506679       rs574025488       rs574031938       rs574326408       rs574497389       rs574659609       rs574703444       rs574705064       rs575040138       rs575099118       rs575427720       rs575758117       rs575995195       rs576067943       rs576110491       rs576803129       rs576860803       rs576974269       rs577098610       rs577237632       rs578000014       rs745448638       rs745520350       rs745741258       rs745819504       rs746349213       rs746683639       rs746957310       rs747126346       rs747270964       rs747465081       rs747475882       rs747501685       rs747756140       rs747999594       rs748272468       rs748311088       rs748530593       rs748690958       rs748899621       rs748900491       rs748910870       rs749145947       rs749733169       rs749823258       rs750088323       rs750232991       rs750787008       rs750830375       rs750848287       rs751078089       rs751148699       rs751503580       rs751693781       rs751727764       rs751735143       rs751782811       rs752072844       rs752234358       rs752308981       rs752617734       rs752619689       rs752884297       rs752925966       rs753557164       rs754355262       rs754376944       rs754404050       rs754428981       rs754620437       rs754753917       rs754989701       rs754990815       rs755217903       rs755219913       rs755495174       rs755720910       rs756084885       rs756154538       rs756485458       rs756635402       rs756730533       rs756851822       rs756905166       rs756928297       rs757018334       rs757303234       rs757508821       rs757551788       rs757613838       rs757835751       rs758015521       rs758220246       rs758263651       rs758535882       rs758643291       rs758686490       rs759092983       rs759209423       rs759244596       rs759304012       rs759841256       rs759956479       rs760063162       rs760198839       rs760404594       rs760642032       rs761158934       rs761254160       rs761467317       rs761562769       rs761685088       rs761761638       rs761786807       rs761973154       rs762074743       rs762204012       rs762413823       rs762883647       rs763107714       rs763187112       rs763221070       rs763276359       rs763308431       rs763547729       rs763648442       rs763699561       rs763712130       rs763999020       rs764190602       rs764442691       rs764761215       rs764891958       rs764976379       rs765031276       rs765032546       rs765236472       rs765365122       rs765488659       rs765910944       rs766003792       rs766175711       rs766529325       rs766607647       rs766953569       rs767008912       rs767064205       rs767119816       rs767354403       rs767504264       rs767632034       rs768409301       rs768462459       rs768553195       rs768915145       rs769025070       rs769093085       rs769202169       rs769389813       rs769537977       rs769712375       rs770130262       rs770229453       rs770854365       rs770907661       rs771080877       rs771331915       rs771333191       rs771721373       rs771772325       rs771818189       rs772093910       rs772200079       rs772232271       rs772553731       rs772568809       rs772605147       rs772802798       rs772976110       rs773078047       rs773424492       rs773429760       rs773443436       rs773482533       rs773514336       rs773813715       rs773869714       rs774104363       rs774157164       rs774229244       rs774340618       rs774565375       rs774936657       rs775376096       rs775454367       rs775607231       rs775989958       rs776275166       rs776365764       rs776375684       rs776483347       rs776832744       rs776846645       rs777456343       rs777542955       rs777617571       rs777686286       rs778563366       rs778577283       rs778682150       rs779359639       rs779366374       rs779398227       rs779680895       rs779975084       rs780029040       rs780098042       rs780199717       rs780214603       rs780319718       rs780338181       rs780474175       rs780480956       rs780575798       rs781114912       rs781229617       rs781591736       rs781752607      

基因表达

基因表达

TFAP2C基因在不同组织中的表达：    [UniProt]

基因在不同组织中的表达图

基因引物

基因引物

正向引物序列
正向引物Tm值
反向引物序列
反向引物Tm值
rank
ATCCTTAGTAGAAGGTGAAGCT
58
ACTGGTTTACTAGGAAATTCGG
58
CATCCTTAGTAGAAGGTGAAGCT
59
CTGGTTTACTAGGAAATTCGGC
59
TCCTTAGTAGAAGGTGAAGCTG
59
CACTGGTTTACTAGGAAATTCGG
59

转录因子

转录因子

转录因子
影响类型
PubMed链接
CDKN1A
Repression
22371483
CRABP2
Activation
17187826
CSTA
Unknown
11095974
ECM1
Activation
17187826
ECM1
Unknown
24023917
ERBB2
Unknown
10645007
ESR1
Activation
11278455     19458056    
GPX1
Activation
22964634
MMP2
Unknown
19853299
RET
Unknown
22878616

基因本体信息

TFAP2C基因（以及对应的蛋白质）的细胞分布位置：

[UniProt]     [GenomeNet]

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • 溶酶体
  • 内涵体
  • 细胞核
  • 细胞质
  • 液泡
  • 细胞膜
  • 细胞外基质
  • 内质网
  • 线粒体
  • 高尔基体
  • 细胞骨架

TFAP2C基因的本体（GO）信息：

GO库代码
对应的蛋白质
来源代码
GO:0003700
A2A2R7(UniProtKB)
IEA
GO:0005634
A2A2R7(UniProtKB)
IEA
GO:0006355
A2A2R7(UniProtKB)
IEA
GO:0000122
Q92754(UniProtKB)
IEA
GO:0000977
Q92754(UniProtKB)
IBA
GO:0001047
Q92754(UniProtKB)
IDA
GO:0001077
Q92754(UniProtKB)
IDA
GO:0001078
Q92754(UniProtKB)
IDA
GO:0003677
Q92754(UniProtKB)
IDA
GO:0003700
Q92754(UniProtKB)
TAS
GO:0005515
Q92754(UniProtKB)
IPI
GO:0005515
Q92754(UniProtKB)
IPI
GO:0005515
Q92754(UniProtKB)
IPI
GO:0005515
Q92754(UniProtKB)
IPI
GO:0005515
Q92754(UniProtKB)
IPI
GO:0005515
Q92754(UniProtKB)
IPI
GO:0005515
Q92754(UniProtKB)
IPI
GO:0005515
Q92754(UniProtKB)
IPI
GO:0005634
Q92754(UniProtKB)
IDA
GO:0005654
Q92754(UniProtKB)
IDA
GO:0005739
Q92754(UniProtKB)
IDA
GO:0006357
Q92754(UniProtKB)
TAS
GO:0006366
Q92754(UniProtKB)
IEA
GO:0007267
Q92754(UniProtKB)
TAS
GO:0008584
Q92754(UniProtKB)
IEP
GO:0040029
Q92754(UniProtKB)
IMP
GO:0042127
Q92754(UniProtKB)
IBA
GO:0045944
Q92754(UniProtKB)
IDA
GO:0046983
Q92754(UniProtKB)
IDA

基因相互作用关系

基因相互作用关系

基因与其他基因之间的相互作用关系图
序号 作用方式 资源库来源/分值 基因名称 基因名称

基因相关microRNA

基因相关microRNA

可能调控TFAP2C基因的相关microRNA：     

基因通路图

基因通路图

基因的通路属性图
通路基因列表

基因相关疾病

基因相关疾病

疾病名称 关系值 NofPmids NofSnps 来源
疾病名称 关系值 NofPmids NofSnps 来源
Stomach Neoplasms 0.12 1 0 CTD_human
Mammary Neoplasms 0.011440285 5 0 BeFree_LHGDN
Breast Carcinoma 0.003257302 12 0 BeFree
Malignant neoplasm of breast 0.002714419 10 0 BeFree
Carcinogenesis 0.000814326 3 0 BeFree
melanoma 0.000542884 2 0 BeFree
Seminoma 0.000542884 2 0 BeFree
Endometrial Carcinoma 0.000542884 2 0 BeFree
Fibroid Tumor 0.000271442 1 0 BeFree
Neuroblastoma 0.000271442 1 0 BeFree
Uterine Fibroids 0.000271442 1 0 BeFree
Agenesis of corpus callosum 0.000271442 1 0 BeFree
Central neuroblastoma 0.000271442 1 0 BeFree
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 0.000271442 1 0 BeFree

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