TCAP(titin-cap) 转至新版数据库

基因基本信息

基因基本信息

基因简称(symbol)
    [HGNC]     [GeneCards]     [NCBI]
基因种类(locus group)
同源简称(alias symbol)
基因家族代码(gene_family_id)
    [HGNC]     [GenScript]
omim代码
entrez码
    [Vega]
vega基因码
ensembl基因码
    [Ensembl]
基因家族(gene family)
refseq数据库代号

更多...

基因种类(locus_type)
基因名称状态(status)
location_sortable
同源基因名称(alias name)
基因名称批准使用时间(date_approved_reserved)
基因简称更名时间(date_symbol_changed)
基因名称更名时间(date_name_changed)
更新时间(date_modified)
ucsc码
ena
ccds数据码
uniprot数据码
pubmed代码
mgd码
rgd码
生命科学数据库(lsdb)
更新时间(date modified)
cosmic
mirbase
基因曾用简称(prev symbol)
基因曾用名称(prev name)
homeodb
cosmic
snornabase
bioparadigms slc
orphanet
假基因信息(pseudogeneorg)
horde id
merops
imgt
iuphar
kznf基因类别
mamit-trnadb
cd
LncRNA数据库
酶代码
中间纤维数据库

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基因染色体位置

基因染色体位置

17q12
基因染色体位置图

基因简述

基因简述

Sarcomere assembly is regulated by the muscle protein titin. Titin is a giant elastic protein with kinase activity that extends half the length of a sarcomere. It serves as a scaffold to which myofibrils and other muscle related proteins are attached. This gene encodes a protein found in striated and cardiac muscle that binds to the titin Z1-Z2 domains and is a substrate of titin kinase, interactions thought to be critical to sarcomere assembly. Mutations in this gene are associated with limb-girdle muscular dystrophy type 2G. [provided by RefSeq, Jul 2008]

[中文简述(自动翻译):]  肌节组件由肌肉蛋白质肌联蛋白调节。肌联蛋白是一个巨大的弹性蛋白与该延伸的肌节的长度的一半激酶活性。它作为向其中的肌原纤维和其他肌肉相关蛋白附着的支架。该基因编码在结合所述肌联蛋白Z 1 -Z 2域和是肌联蛋白激酶，被认为是对肌节组件至关重要的相互作用的基板横纹肌和心肌中发现的蛋白质。在这种基因突变与肢带型肌营养不良2G相关联。 [由RefSeq的，2008年7月提供]

OMIM数据库中对TCAP基因的介绍     Wikipedia数据库中对TCAP基因的介绍

基因序列

基因序列

TCAP基因的碱基序列：[NCBI]

基因突变

基因突变

TCAP基因的碱基突变：           显示全部snp
rs1053651       rs3194794       rs45459794       rs45495400       rs45500896       rs45503594       rs45506294       rs45509691       rs45521334       rs45540732       rs45576834       rs45592941       rs45593534       rs45598738       rs45614332       rs112505294       rs147503632       rs149585781       rs183877110       rs185210946       rs188530675       rs200333339       rs374886575       rs375843419       rs397516864       rs397897576       rs529897184       rs532000115       rs534551291       rs546458301       rs548081211       rs553353838       rs554308696       rs558480997       rs558774503       rs558790192       rs559315591      
rs564811279       rs569522916       rs571366329       rs575907312       rs577303207       rs748358368       rs748365337       rs749685550       rs749817987       rs755395354       rs755539784       rs761498487       rs762850913       rs762976588       rs763965899       rs768942598       rs769800632       rs771072422       rs771363240       rs772083153       rs773317399       rs773653957       rs774447573       rs775624321       rs777817968       rs779217085       rs780544264       rs1050321       rs1802512       rs2934962       rs2941511       rs45450597       rs45469091       rs45519441       rs45526035       rs45591632       rs45628436       rs71369784       rs113400596       rs115929562       rs142285426       rs142529105       rs145241630       rs147109217       rs150235121       rs151239544       rs181036831       rs182065817       rs185500997       rs186919652       rs370725001       rs372539531       rs529235725       rs531842879       rs533425866       rs533491079       rs534183321       rs538169484       rs539098719       rs540206554       rs540528743       rs544528446       rs555094594       rs556025471       rs556305753       rs556368886       rs557831344       rs561684636       rs562628358       rs562992011       rs563916473       rs564203638       rs566901296       rs567927745       rs569354848       rs571423936       rs572892668       rs573952745       rs577912616       rs931992       rs2934963       rs2941510       rs17554665       rs17851031       rs35821333       rs45458802       rs45465992       rs45469691       rs45473099       rs45492903       rs45495192       rs45513698       rs45521936       rs45550442       rs45578741       rs45592531       rs45604543       rs45614536       rs45627533       rs58627150       rs74485609       rs75353839       rs77831798       rs112704484       rs112769900       rs113612868       rs115582106       rs138459354       rs141019458       rs143233087       rs143465226       rs144149447       rs144450249       rs144741021       rs145524909       rs146502276       rs146906267       rs147979713       rs187261074       rs192253142       rs199865814       rs201664428       rs202064946       rs367995009       rs368175926       rs369447207       rs372049483       rs372312912       rs372538567       rs374765013       rs375116257       rs375310569       rs375389509       rs397516861       rs531594088       rs532719898       rs535319258       rs537827145       rs538573104       rs541368606       rs542765340       rs547939362       rs549098951       rs549769566       rs549802915       rs552865793       rs556223066       rs556489914       rs560043555       rs560110882       rs560900534       rs564958287       rs565221860       rs567350904       rs567412273       rs571654975       rs572836774       rs576098128       rs577978779       rs578027213       rs727503455       rs746219012       rs746905747       rs747005525       rs748506107       rs748882218       rs749013902       rs749402903       rs749565002       rs750306897       rs750429579       rs750742898       rs750796201       rs752435787       rs752739003       rs752894436       rs753599743       rs753744791       rs754054712       rs754744780       rs754762491       rs754946182       rs755965751       rs756017005       rs756375255       rs756548785       rs756715463       rs757082868       rs757117448       rs757657130       rs758048577       rs758101613       rs758142728       rs758460755       rs759645275       rs759893644       rs761260032       rs761833243       rs761888264       rs762224660       rs762433998       rs763037167       rs764200782       rs764350236       rs766260041       rs767577344       rs767763640       rs768889521       rs769455424       rs770133993       rs770194856       rs771585295       rs772728707       rs773705016       rs773816898       rs773913117       rs774516749       rs775080606       rs775636212       rs776376622       rs777153450       rs777384494       rs777518512       rs777779763       rs778568339       rs778851652       rs779699520       rs779822505       rs779949893       rs780752425       rs781560443      

基因表达

基因表达

TCAP基因在不同组织中的表达：    [UniProt]

基因在不同组织中的表达图

基因引物

基因引物

正向引物序列
正向引物Tm值
反向引物序列
反向引物Tm值
rank
ATCTGACACTGTCCACACG
60
CATGTCTCTGGGTGTCCTC
60
GATCTGACACTGTCCACAC
58
CATGTCTCTGGGTGTCCTC
60
ATCTGACACTGTCCACACG
60
CATGTCTCTGGGTGTCCTC
60
GATCTGACACTGTCCACAC
58
CATGTCTCTGGGTGTCCTC
60
ATCTGACACTGTCCACACG
60
CTCATGTCTCTGGGTGTCC
60
ATCTGACACTGTCCACACG
60
CTCATGTCTCTGGGTGTCC
60

转录因子

转录因子

      尚未收录相关数据

基因本体信息

TCAP基因（以及对应的蛋白质）的细胞分布位置：

[UniProt]     [GenomeNet]

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • 溶酶体
  • 内涵体
  • 细胞核
  • 细胞质
  • 液泡
  • 细胞膜
  • 细胞外基质
  • 内质网
  • 线粒体
  • 高尔基体
  • 细胞骨架

TCAP基因的本体（GO）信息：

GO库代码
对应的蛋白质
来源代码
GO:0001756
O15273(UniProtKB)
IEA
GO:0003009
O15273(UniProtKB)
IEP
GO:0003300
O15273(UniProtKB)
IMP
GO:0005515
O15273(UniProtKB)
IPI
GO:0005515
O15273(UniProtKB)
IPI
GO:0005515
O15273(UniProtKB)
IPI
GO:0005515
O15273(UniProtKB)
IPI
GO:0005515
O15273(UniProtKB)
IPI
GO:0005515
O15273(UniProtKB)
IPI
GO:0005515
O15273(UniProtKB)
IPI
GO:0005515
O15273(UniProtKB)
IPI
GO:0005515
O15273(UniProtKB)
IPI
GO:0005515
O15273(UniProtKB)
IPI
GO:0005515
O15273(UniProtKB)
IPI
GO:0005829
O15273(UniProtKB)
TAS
GO:0005829
O15273(UniProtKB)
TAS
GO:0005829
O15273(UniProtKB)
TAS
GO:0005829
O15273(UniProtKB)
TAS
GO:0006461
O15273(UniProtKB)
TAS
GO:0007512
O15273(UniProtKB)
IMP
GO:0008307
O15273(UniProtKB)
IMP
GO:0014898
O15273(UniProtKB)
IMP
GO:0030018
O15273(UniProtKB)
IDA
GO:0030018
O15273(UniProtKB)
IDA
GO:0030049
O15273(UniProtKB)
TAS
GO:0030240
O15273(UniProtKB)
IMP
GO:0030241
O15273(UniProtKB)
IMP
GO:0030674
O15273(UniProtKB)
IDA
GO:0030916
O15273(UniProtKB)
IEA
GO:0031432
O15273(UniProtKB)
IPI
GO:0031432
O15273(UniProtKB)
IPI
GO:0031432
O15273(UniProtKB)
IPI
GO:0031674
O15273(UniProtKB)
ISS
GO:0035994
O15273(UniProtKB)
TAS
GO:0035995
O15273(UniProtKB)
IMP
GO:0036122
O15273(UniProtKB)
IPI
GO:0044325
O15273(UniProtKB)
IPI
GO:0045214
O15273(UniProtKB)
TAS
GO:0045214
O15273(UniProtKB)
IMP
GO:0048739
O15273(UniProtKB)
IMP
GO:0048769
O15273(UniProtKB)
IMP
GO:0050982
O15273(UniProtKB)
TAS
GO:0051373
O15273(UniProtKB)
IPI
GO:0055003
O15273(UniProtKB)
IMP
GO:0055008
O15273(UniProtKB)
IMP
GO:0060048
O15273(UniProtKB)
IMP
GO:0060048
O15273(UniProtKB)
IMP
GO:0070080
O15273(UniProtKB)
IPI

基因相互作用关系

基因相互作用关系

基因与其他基因之间的相互作用关系图
序号 作用方式 资源库来源/分值 基因名称 基因名称

基因相关microRNA

基因相关microRNA

可能调控TCAP基因的相关microRNA：     

基因通路图

基因通路图

基因的通路属性图
通路基因列表

基因相关疾病

基因相关疾病

疾病名称 关系值 NofPmids NofSnps 来源
疾病名称 关系值 NofPmids NofSnps 来源
Muscular Dystrophy, Limb-Girdle, Type 2G 0.44 0 3 CLINVAR_CTD_human_MGD_ORPHANET
CARDIOMYOPATHY, DILATED, 1N 0.36 2 4 CLINVAR_CTD_human_UNIPROT
Cardiomyopathy, Dilated 0.007915422 5 0 BeFree_GAD
Hypertrophic Cardiomyopathy 0.007729856 3 0 BeFree_GAD_LHGDN
Cardiomyopathies 0.002909916 2 0 BeFree_GAD
Muscular Dystrophies, Limb-Girdle 0.002442977 9 0 BeFree
Cardiomyopathy, Familial Idiopathic 0.002367032 1 0 GAD
Muscular Dystrophy 0.000542884 2 0 BeFree
Malignant neoplasm of breast 0.000271442 1 0 BeFree
Myopathy 0.000271442 1 0 BeFree
Weakness of limb 0.000271442 1 0 BeFree
Breast Carcinoma 0.000271442 1 0 BeFree
Sarcoglycanopathies 0.000271442 1 0 BeFree

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