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This gene is located in the surfeit gene cluster, which is comprised of very tightly linked housekeeping genes that do not share sequence similarity. The encoded protein is a conserved integral membrane protein that interacts with endoplasmic reticulum-Golgi intermediate compartment proteins. Disruption of this gene results in reduced numbers of endoplasmic reticulum-Golgi intermediate compartment clusters and redistribution of coat protein I to the cytosol. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
[中文简述(自动翻译):]  此基因位于过量基因簇,它包括不共享序列相似性非常紧密连锁管家基因的英寸所编码的蛋白质是有内质网,高尔基体中间隔间蛋白相互作用的保守整合膜蛋白。降低内质网高尔基中间车厢集群和外壳蛋白我到细胞质的再分配的人数这个基因导致的破坏。选择性剪接结果在多个抄本变形。 [由RefSeq的,2013年7月提供]
SURF4基因(以及对应的蛋白质)的细胞分布位置:
SURF4基因的本体(GO)信息:
疾病名称 | 关系值 | NofPmids | NofSnps | 来源 |
Prostatic Neoplasms | 0.12 | 1 | 0 | CTD_human |
Tobacco Use Disorder | 0.002367032 | 1 | 0 | GAD |
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