SREBF1(sterol regulatory element binding transcription factor 1)

基因简称(symbol)
    [HGNC]     [GeneCards]     [NCBI]
基因种类(locus group)
同源简称(alias symbol)
基因家族代码(gene_family_id)
    [HGNC]     [GenScript]
omim代码
entrez码
    [Vega]
vega基因码
ensembl基因码
    [Ensembl]
基因家族(gene family)
refseq数据库代号

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基因种类(locus_type)
基因名称状态(status)
location_sortable
同源基因名称(alias name)
基因名称批准使用时间(date_approved_reserved)
基因简称更名时间(date_symbol_changed)
基因名称更名时间(date_name_changed)
更新时间(date_modified)
ucsc码
ena
ccds数据码
uniprot数据码
pubmed代码
mgd码
rgd码
生命科学数据库(lsdb)
更新时间(date modified)
cosmic
mirbase
基因曾用简称(prev symbol)
基因曾用名称(prev name)
homeodb
cosmic
snornabase
bioparadigms slc
orphanet
假基因信息(pseudogeneorg)
horde id
merops
imgt
iuphar
kznf基因类别
mamit-trnadb
cd
LncRNA数据库
酶代码
中间纤维数据库

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17p11.2
基因染色体位置图

This gene encodes a transcription factor that binds to the sterol regulatory element-1 (SRE1), which is a decamer flanking the low density lipoprotein receptor gene and some genes involved in sterol biosynthesis. The protein is synthesized as a precursor that is attached to the nuclear membrane and endoplasmic reticulum. Following cleavage, the mature protein translocates to the nucleus and activates transcription by binding to the SRE1. Sterols inhibit the cleavage of the precursor, and the mature nuclear form is rapidly catabolized, thereby reducing transcription. The protein is a member of the basic helix-loop-helix-leucine zipper (bHLH-Zip) transcription factor family. This gene is located within the Smith-Magenis syndrome region on chromosome 17. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

[中文简述(自动翻译):]  这个基因编码结合所述固醇调节元件-1(S??RE1),这是一种十聚体侧翼的低密度脂蛋白受体基因和参与固醇生物合成某些基因的转录因子。该蛋白质被合成为一个连接到在核膜和内质网的前体。以下裂解,成熟蛋白转位到细胞核并通过结合到SRE1激活转录。固醇抑制前体的裂解,和成熟的核形式迅速分解代谢,由此降低转录。该蛋白是基本螺旋 - 环 - 螺旋 - 亮氨酸拉链(bHLH结构-Zip的)转录因子家族的一个成员。该基因位于史密斯马盖尼斯综合征区域内对染色体17的两个转录物变体编码不同同种型已发现此基因。 [由RefSeq的,2008年7月提供]

SREBF1基因的碱基序列:[NCBI]
SREBF1基因的碱基突变:           显示全部snp
rs1042017       rs1737957       rs1737958       rs1737959       rs2297507       rs11653007       rs13306738       rs17855792       rs34882915       rs35014224       rs45567732       rs45581135       rs56088670       rs56155608       rs70937020       rs74911175       rs112461082       rs112841913       rs113020824       rs113822354       rs115111429       rs138408324       rs138489288       rs139268369       rs140127035       rs141489278       rs142115026       rs143021204       rs143432557       rs143589263       rs146124521       rs146807226       rs147603937       rs149239470       rs149639334       rs150846293       rs184208843      
rs191900683       rs199944765       rs200275446       rs200341188       rs200944690       rs201090006       rs201248028       rs201456097       rs202180542       rs367863132       rs368709922       rs368912504       rs369265246       rs369513276       rs371224082       rs371518920       rs371767440       rs371883515       rs372699126       rs372841919       rs373012055       rs373272335       rs373852721       rs373874679       rs374223517       rs374501408       rs374955252       rs375235305       rs375637668       rs375687681       rs375703363       rs375846318       rs375856719       rs376052173       rs377040357       rs529460681       rs529523881       rs529967568       rs530843182       rs531973046       rs533346781       rs533412704       rs534092070       rs536159487       rs536487832       rs537879948       rs537926232       rs537939492       rs538485538       rs541938568       rs542965377       rs543156769       rs544476184       rs545110414       rs545664723       rs547294196       rs548792177       rs549088591       rs549691899       rs550847379       rs553654626       rs554025480       rs554064175       rs554098807       rs555578434       rs556284190       rs556932635       rs557824895       rs557863648       rs560879600       rs562244777       rs564110856       rs564483083       rs565016555       rs567599251       rs568978565       rs569500037       rs569536802       rs571243616       rs571282377       rs571666726       rs572068338       rs572905301       rs573740725       rs573803122       rs573974789       rs574231164       rs575226847       rs575287529       rs576886028       rs577605504       rs577962730       rs745401185       rs745466186       rs745682611       rs745947295       rs746518916       rs747099562       rs747376487       rs747566298       rs747606634       rs747986866       rs748188434       rs748241108       rs748467290       rs748519015       rs748715164       rs748730943       rs748755763       rs748957764       rs749088010       rs749283714       rs749460624       rs749479675       rs749621740       rs749896504       rs749984492       rs750166615       rs750730995       rs750820947       rs751021350       rs751359227       rs752108127       rs752435218       rs752440934       rs753192409       rs753379159       rs753564046       rs753588115       rs753595573       rs754566804       rs754832342       rs755462211       rs755468102       rs755476286       rs755701419       rs755722353       rs755965677       rs756298683       rs756603047       rs756666181       rs756696543       rs756896447       rs757078927       rs757634010       rs758106438       rs758827942       rs758921524       rs759051651       rs759425163       rs759431426       rs759629607       rs759785838       rs760193821       rs760352664       rs760448922       rs760490549       rs760812071       rs760943096       rs761525507       rs761664089       rs761768810       rs762653602       rs762852913       rs762908697       rs762911298       rs763134830       rs763151522       rs763273627       rs763645145       rs763669855       rs763800879       rs763966743       rs764217259       rs764398975       rs764653544       rs764969616       rs765083139       rs765741111       rs765939564       rs766132533       rs766223222       rs766298145       rs766530772       rs766620577       rs766697267       rs766703763       rs766989166       rs767124369       rs767291140       rs767433200       rs767449624       rs767791838       rs768195955       rs768320582       rs768387797       rs768579321       rs768686040       rs768989117       rs769307775       rs769761001       rs769850076       rs770043787       rs770235804       rs770692038       rs770901003       rs771046469       rs771091928       rs771131054       rs771171102       rs771472597       rs771791469       rs771905238       rs772036773       rs772174935       rs773162568       rs773187533       rs773284975       rs773550293       rs773687594       rs773775877       rs773938321       rs774027813       rs774351428       rs774433456       rs774618594       rs774799570       rs774987132       rs775091521       rs775182965       rs775300645       rs775360484       rs775381502       rs775467840       rs775933323       rs776419406       rs776489118       rs776592557       rs776697983       rs776981703       rs777095431       rs777499664       rs777924764       rs778032338       rs778158697       rs778161281       rs778212443       rs778435014       rs778925742       rs779203060       rs779262943       rs779650858       rs779739510       rs779777187       rs780391933       rs780613862       rs780767551       rs781153095       rs781158826       rs781581475       rs781755403       rs781767781       rs12941356       rs28657889       rs77136610       rs374213055       rs528539884       rs540476580       rs544495508       rs555028750       rs560295995       rs575216271       rs748838459       rs753476023       rs754834600       rs761113013       rs763678884       rs776118202       rs777111276       rs780793583       rs1737962       rs11868035       rs13306739       rs13306741       rs73981075       rs79080059       rs137899785       rs138625473       rs143430327       rs143628855       rs148898291       rs188868996       rs368236067       rs397718365       rs529883577       rs538831427       rs539137740       rs542086603       rs546878749       rs550233963       rs550455439       rs550868299       rs554989823       rs558891176       rs561868649       rs572773624       rs574958299       rs751534268       rs752181202       rs752344306       rs758730057       rs759039705       rs759219352       rs760113790       rs765758533       rs766348360       rs767025491       rs767103603       rs774129267       rs777738776       rs779177135       rs780446053       rs781283978       rs874163       rs1042024       rs1062463       rs1108511       rs1737960       rs1889016       rs1889018       rs2228461       rs2229590       rs2229591       rs2282180       rs2297508       rs3181513       rs3785497       rs3785498       rs4924821       rs4925115       rs4925116       rs4925117       rs4925118       rs7214136       rs7359509       rs7501788       rs7503739       rs7503747       rs8064706       rs8066560       rs8067280       rs9894257       rs9898044       rs9899537       rs9899634       rs9902941       rs9907536       rs11078399       rs11541608       rs11652144       rs11652574       rs11652861       rs11656665       rs11657130       rs11657274       rs11657423       rs11869628       rs12450799       rs12601420       rs12936927       rs12938501       rs12941068       rs12946746       rs12952723       rs12953299       rs13306736       rs13306737       rs13306742       rs17854924       rs17855793       rs28521648       rs28528721       rs28533148       rs34380995       rs34613592       rs34657912       rs35188700       rs35367147       rs35602152       rs35763683       rs35858976       rs35868099       rs36215896       rs45535737       rs45570037       rs55759875       rs55879728       rs55935158       rs56061659       rs56174147       rs56248913       rs57195963       rs57966878       rs58189290       rs59019513       rs59221617       rs59995125       rs60067423       rs60948138       rs61329156       rs62064117       rs62064118       rs62064119       rs67686620       rs70937018       rs70937019       rs71155305       rs71372210       rs73297846       rs73297851       rs73297855       rs73297859       rs73297865       rs73297868       rs73979203       rs73981076       rs73981078       rs74520623       rs74630210       rs75507733       rs75904465       rs76311727       rs76423354       rs76463685       rs76959280       rs77370813       rs77391284       rs77452677       rs77831205       rs77908814       rs77941406       rs78183076       rs78663745       rs78711184       rs78735444       rs78736935       rs79821058       rs80057313       rs111396201       rs111412713       rs111456445       rs111485267       rs111683968       rs111725386       rs111946564       rs112126691       rs112151547       rs112173582       rs112303966       rs112726100       rs112947968       rs112966033       rs113203245       rs113396102       rs113529790       rs114001633       rs114018671       rs114130125       rs114978947       rs115052373       rs115121194       rs115341498       rs115376028       rs115403432       rs115746214       rs115783368       rs115855236       rs115905069       rs115951804       rs116014387       rs116340103       rs116464536       rs116542837       rs116660665       rs116762843       rs116935243       rs117599491       rs117867371       rs117947006       rs137858867       rs138341129       rs138410530       rs138688211       rs138746790       rs138960646       rs138979097       rs139027236       rs139067895       rs139207866       rs139267544       rs139373457       rs139533847       rs139775563       rs139788922       rs139792387       rs140133677       rs140341844       rs140463203       rs140556398       rs140585468       rs140650790       rs140670394       rs140704969       rs140780362       rs140847903       rs141086741       rs141409580       rs141503556       rs141784290       rs141843309       rs141870250       rs141918632       rs142128892       rs142222039       rs142258862       rs142521701       rs142887672       rs143024466       rs143109118       rs143161020       rs143191237       rs143373842       rs143522203       rs143774353       rs144041794       rs144225515       rs144506262       rs144771074       rs144842792       rs144880471       rs145115844       rs145176417       rs145253872       rs145295794       rs145316050       rs145632277       rs145784091       rs145824670       rs146219051       rs146296698       rs146406290       rs146685884       rs146987437       rs147049885       rs147187399       rs147213271       rs147235909       rs147246061       rs147255505       rs147268500       rs147494298       rs147626066       rs147642834       rs147957391       rs148076583       rs148306367       rs148334380       rs148462234       rs148852047       rs149202767       rs149265858       rs149288632       rs149397348       rs149599437       rs149965532       rs149989037       rs150283474       rs150300072       rs150312441       rs150458577       rs150599085       rs150634326       rs150790448       rs150874158       rs150947827       rs151099135       rs151195372       rs151198415       rs180780951       rs180873030       rs180926312       rs181117649       rs181465552       rs181872273       rs181949704       rs182050803       rs182164945       rs182318290       rs182701073       rs182796727       rs183573218       rs184467989       rs184606504       rs184751515       rs184895700       rs185346403       rs185414313       rs185713815       rs186104879       rs186373805       rs186383830       rs186482219       rs186504593       rs186516255       rs186942019       rs187099071       rs187274368       rs187382490       rs187408367       rs187743101       rs187824343       rs188036993       rs188172253       rs188182123       rs188520844       rs188765351       rs189589388       rs189694492       rs189798008       rs189872693       rs190283794       rs190497117       rs190527750       rs190603744       rs190626886       rs190928308       rs191029417       rs191151621       rs191206780       rs191301839       rs191478871       rs192087293       rs192165800       rs192662966       rs192671411       rs192799690       rs193139262       rs193176383       rs199509789       rs199683246       rs199775670       rs199794521       rs199843574       rs200023224       rs200041009       rs200411629       rs200448526       rs200515471       rs200530841       rs200577288       rs200639307       rs200650254       rs200676239       rs200774642       rs201297376       rs201326212       rs201406957       rs201544341       rs201648502       rs201688246       rs201769377       rs201773379       rs202078828       rs202244145       rs367557510       rs367758777       rs367891169       rs367985942       rs368049193       rs368174566       rs368205954       rs368232810       rs368296518       rs368324517       rs368488019       rs368766565       rs368954390       rs369121847       rs369140201       rs369147925       rs369312304       rs369375752       rs369811238       rs369842028       rs370005563       rs370217056       rs370259694       rs370488355       rs370517296       rs370626820       rs370714402       rs370794086       rs371153541       rs371247619       rs371263092       rs371458839       rs371639022       rs371667718       rs371853918       rs372028527       rs372103234       rs372105506       rs372134609       rs372230663       rs372236999       rs372684525       rs372983389       rs373021220       rs373183346       rs373261922       rs373300837       rs373675923       rs373711886       rs374192592       rs374206129       rs374242472       rs374456007       rs374465060       rs374509373       rs374510804       rs374628320       rs375059574       rs375091189       rs375278694       rs375304529       rs375322792       rs375324028       rs375671518       rs376044798       rs376250994       rs376423372       rs376434701       rs376445991       rs376568410       rs376704400       rs376918339       rs377235385       rs377273429       rs377633153       rs377727800       rs377749662       rs397824407       rs527323273       rs527531217       rs527557883       rs527638563       rs527668474       rs527733577       rs527757985       rs527794295       rs528007537       rs528480634       rs528509170       rs528518669       rs528731436       rs528768531       rs528927159       rs528968412       rs529168675       rs529543534       rs529689353       rs530183030       rs530223009       rs530606668       rs531078297       rs531079618       rs531116837       rs531373893       rs531435440       rs531610965       rs531827631       rs532090376       rs532238931       rs532246976       rs532379353       rs532576137       rs532590705       rs532616326       rs532671042       rs532816791       rs532898327       rs533018650       rs533072867       rs533411970       rs533522952       rs533795120       rs533982358       rs534269158       rs534395591       rs534432681       rs534475083       rs534477547       rs534518261       rs534619818       rs534658050       rs534778549       rs534953196       rs535206411       rs535365697       rs535408367       rs535412359       rs535437019       rs535478552       rs535533595       rs535545433       rs535598849       rs535729328       rs535765772       rs535974096       rs536083511       rs536727932       rs536920802       rs536935463       rs536962782       rs536970275       rs537152415       rs537507909       rs537541432       rs537595456       rs537837933       rs537948037       rs538153457       rs538315328       rs538322672       rs538341574       rs538520689       rs538526968       rs538912477       rs539120019       rs539132684       rs539270535       rs539330632       rs539337656       rs539350578       rs539465970       rs539532044       rs539729973       rs539906018       rs540325620       rs540361433       rs540624816       rs540785820       rs540786408       rs540795370       rs541139996       rs541501742       rs541528658       rs541777331       rs541913785       rs541938925       rs542188127       rs542223201       rs542375631       rs542734853       rs542771924       rs542966667       rs543194176       rs543541214       rs543638556       rs543721197       rs543762144       rs543981369       rs544294164       rs544489659       rs544532333       rs544637727       rs544754322       rs544799773       rs544936958       rs545111273       rs545168057       rs545199878       rs545265110       rs545484767       rs545521576       rs545638894       rs545736442       rs545963966       rs545980923       rs546001142       rs546084125       rs546138693       rs546297883       rs546301067       rs546370621       rs546588860       rs546623823       rs546748008       rs547192214       rs547527686       rs547777848       rs547779696       rs547816038       rs547922065       rs548191884       rs548244440       rs548339709       rs548376716       rs548852542       rs549047292       rs549051709       rs549064656       rs549493219       rs550158924       rs550206550       rs550376061       rs550400301       rs550438872       rs550472029       rs550494720       rs550686227       rs550724603       rs551317529       rs551419210       rs551455878       rs551561906       rs551618205       rs551792079       rs551811201       rs551910387       rs552345574       rs552359572       rs552362788       rs552640953       rs552659966       rs552679724       rs552775287       rs552926839       rs553273927       rs553304997       rs553346965       rs553900455       rs554034741       rs554120561       rs554155669       rs554209642       rs554362346       rs554545075       rs554570759       rs554597213       rs554828730       rs554897947       rs555008193       rs555284676       rs555313544       rs555575360       rs555743234       rs555834927       rs555870026       rs556024347       rs556637207       rs556691960       rs556725933       rs556767314       rs556857650       rs556930711       rs557095159       rs557210142       rs557219085       rs557268670       rs557306654       rs557473047       rs557676461       rs557905824       rs557953261       rs558104352       rs558113480       rs558139183       rs558212189       rs558274961       rs558364254       rs558393829       rs558531896       rs559111955       rs559261092       rs559431273       rs559510632       rs559514103       rs559571792       rs559836298       rs559924216       rs560215927       rs560680589       rs560800413       rs560858317       rs560896575       rs560916457       rs560938039       rs561102110       rs561252813       rs561417343       rs561665063       rs561757838       rs561839171       rs561875762       rs561929468       rs562076884       rs562092413       rs562141425       rs562165527       rs562366971       rs562487398       rs562525105       rs562907288       rs562951727       rs563085112       rs563289678       rs563322169       rs563515554       rs563546188       rs563551814       rs563682870       rs564101415       rs564243706       rs564282517       rs564682293       rs564687311       rs564729529       rs564840650       rs564878792       rs564988389       rs565098931       rs565252282       rs565289562       rs565300608       rs565436449       rs565959180       rs566194816       rs566498131       rs566513103       rs566813131       rs567149060       rs567648501       rs567649807       rs567685904       rs567761336       rs567774753       rs567813810       rs567855858       rs567918532       rs567959489       rs568106693       rs568297471       rs568336585       rs568336689       rs568608485       rs568851975       rs568893008       rs568917551       rs568928566       rs568941442       rs569027787       rs569229485       rs569265623       rs569535249       rs569885314       rs570082363       rs570141771       rs570225641       rs570382690       rs570576513       rs570727494       rs570757104       rs571172901       rs571411526       rs571425275       rs571603576       rs571696333       rs571971435       rs572006170       rs572007557       rs572035215       rs572545881       rs572574921       rs572818613       rs572936794       rs573074285       rs573136655       rs573153563       rs573688436       rs573750330       rs574091995       rs574127320       rs574278824       rs574317391       rs574342012       rs574360054       rs574843165       rs574953275       rs575225193       rs575505995       rs575569301       rs575580016       rs575789692       rs575811265       rs575863492       rs575898165       rs576022756       rs576051502       rs576092514       rs576422756       rs576503729       rs576633687       rs576673145       rs576865566       rs576927442       rs577027898       rs577071480       rs577108529       rs577793798       rs577980911       rs578138733       rs578234399       rs745341275       rs745352783       rs745442700       rs745458579       rs745478097       rs745521576       rs745626639       rs745649813       rs745723863       rs745743489       rs745773928       rs745825161       rs745830874       rs745947246       rs745976144       rs746010358       rs746029158       rs746121980       rs746289067       rs746291029       rs746312359       rs746334705       rs746519163       rs746535471       rs746664567       rs746687245       rs746795124       rs746889221       rs746890886       rs746953838       rs746969883       rs747091340       rs747117647       rs747159283       rs747160124       rs747351493       rs747564993       rs747592710       rs747596305       rs747625180       rs747766126       rs747766684       rs747971350       rs748011956       rs748015131       rs748039234       rs748109057       rs748271244       rs748289091       rs748338457       rs748527487       rs748528832       rs748561715       rs748652493       rs748666407       rs748720804       rs748821066       rs748851590       rs748861159       rs748929980       rs748930258       rs749003944       rs749029874       rs749108406       rs749143932       rs749164113       rs749201387       rs749290010       rs749330660       rs749413444       rs749426882       rs749427888       rs749458271       rs749534809       rs749645228       rs749748482       rs749760887       rs749919446       rs749997116       rs750206827       rs750227083       rs750227184       rs750229782       rs750536079       rs750606535       rs750626602       rs750664659       rs750706961       rs750707066       rs750856545       rs750912722       rs751046860       rs751047506       rs751097981       rs751121039       rs751162760       rs751285599       rs751361652       rs751370995       rs751617325       rs751743721       rs751855027       rs751864404       rs751909921       rs751970106       rs751971116       rs752310522       rs752338341       rs752363887       rs752413049       rs752632237       rs752636983       rs752657895       rs752693771       rs752836029       rs753054739       rs753094126       rs753117423       rs753129914       rs753184138       rs753317507       rs753333250       rs753388357       rs753406111       rs753449443       rs753568996       rs753587590       rs753665179       rs753828343       rs753866396       rs754006347       rs754006664       rs754141844       rs754177360       rs754185856       rs754272248       rs754353221       rs754558022       rs754606220       rs754816475       rs754856257       rs754904001       rs754906587       rs754919921       rs754950812       rs754990773       rs755003247       rs755146465       rs755147325       rs755201140       rs755233563       rs755338995       rs755406167       rs755530742       rs755558569       rs755731244       rs755969074       rs756036476       rs756054956       rs756058766       rs756167038       rs756255308       rs756315141       rs756329553       rs756397641       rs756485342       rs756583841       rs756633226       rs756697799       rs756887361       rs756907325       rs756959735       rs757085390       rs757112939       rs757137820       rs757166717       rs757230938       rs757377752       rs757407198       rs757419059       rs757528274       rs757550989       rs757568428       rs757643996       rs757688389       rs757702864       rs757825722       rs757843997       rs757897976       rs757953927       rs757988948       rs758082732       rs758093457       rs758188725       rs758228846       rs758406307       rs758414939       rs758499150       rs758544446       rs758672245       rs758739978       rs758921309       rs758941272       rs758976021       rs759007731       rs759141530       rs759302336       rs759312298       rs759498014       rs759727281       rs759764219       rs759857699       rs759913430       rs759916156       rs759936388       rs760064779       rs760224973       rs760250425       rs760272214       rs760290524       rs760291795       rs760300935       rs760339970       rs760394850       rs760427795       rs760434634       rs760522955       rs760575569       rs760697644       rs760731876       rs760812255       rs760902013       rs760931114       rs760938572       rs761016541       rs761110252       rs761191463       rs761235663       rs761290771       rs761326412       rs761385181       rs761431872       rs761557831       rs761675701       rs761691604       rs761885261       rs762037863       rs762042920       rs762129149       rs762148202       rs762259135       rs762386526       rs762494350       rs762538826       rs762579250       rs762587398       rs762696464       rs762701559       rs762715776       rs762809461       rs763110206       rs763131303       rs763171952       rs763204061       rs763311132       rs763401166       rs763425045       rs763435141       rs763589105       rs763659053       rs763660773       rs763803649       rs763808864       rs763855640       rs763881788       rs763891333       rs763903320       rs764109614       rs764187194       rs764189077       rs764393395       rs764419751       rs764442896       rs764584565       rs764595232       rs764602703       rs764604749       rs764732043       rs764807273       rs764848528       rs764850318       rs764938327       rs764978100       rs765046599       rs765101236       rs765294323       rs765346808       rs765380054       rs765420663       rs765437644       rs765462041       rs765588636       rs765744562       rs765819176       rs765863137       rs765909002       rs765996698       rs766029447       rs766119144       rs766119997       rs766399427       rs766494383       rs766507641       rs766529379       rs766587240       rs766652407       rs766666530       rs766677516       rs766750448       rs766868316       rs766877167       rs766878437       rs766894230       rs766960601       rs766972039       rs767132358       rs767155649       rs767164203       rs767170938       rs767265515       rs767280978       rs767354190       rs767418391       rs767495773       rs767536004       rs767745516       rs767798892       rs767861530       rs767887376       rs768104999       rs768174420       rs768202611       rs768240923       rs768398640       rs768437611       rs768608062       rs768625249       rs768638210       rs768671095       rs769007537       rs769024663       rs769070267       rs769148884       rs769163290       rs769275980       rs769315699       rs769335094       rs769438496       rs769497316       rs769564165       rs769740446       rs769912210       rs770029528       rs770180248       rs770187401       rs770190474       rs770210923       rs770238327       rs770425962       rs770427377       rs770464344       rs770474599       rs770520507       rs770587190       rs770716460       rs770849678       rs770850320       rs770879546       rs770910678       rs771244150       rs771276198       rs771347177       rs771418665       rs771489805       rs771496847       rs771570816       rs771622611       rs771640474       rs771693366       rs771713083       rs771747343       rs771818317       rs771908308       rs771979633       rs771986536       rs772003607       rs772388841       rs772414598       rs772423937       rs772619133       rs772693476       rs772980238       rs772981357       rs773037704       rs773067590       rs773142004       rs773162643       rs773176031       rs773176450       rs773309258       rs773391894       rs773620604       rs773672551       rs773721880       rs773881829       rs773938914       rs773996426       rs774093514       rs774182881       rs774191561       rs774197198       rs774515195       rs774565019       rs774609594       rs774698338       rs774786382       rs774798173       rs774820966       rs774877271       rs774885553       rs774907149       rs774974924       rs775027982       rs775061143       rs775092228       rs775133501       rs775151936       rs775175384       rs775239369       rs775316121       rs775330185       rs775349039       rs775625400       rs775694011       rs775827225       rs775892357       rs775938228       rs776012182       rs776022873       rs776078731       rs776200304       rs776304644       rs776323149       rs776407617       rs776482975       rs776507816       rs776609977       rs776659320       rs776719475       rs776724133       rs776768645       rs776969673       rs777103239       rs777131011       rs777163950       rs777165983       rs777245770       rs777361028       rs777420812       rs777441484       rs777452057       rs777518127       rs777768669       rs777770840       rs777820660       rs777955940       rs778181026       rs778318730       rs778335677       rs778337895       rs778410055       rs778425601       rs778652136       rs778690686       rs778790003       rs778830955       rs778836279       rs778854295       rs778880151       rs778947924       rs778987370       rs779003609       rs779049810       rs779068780       rs779253568       rs779363276       rs779364056       rs779448117       rs779472546       rs779537987       rs779691100       rs779717362       rs779902496       rs779929514       rs779939202       rs780021688       rs780085509       rs780121769       rs780138877       rs780364091       rs780437419       rs780502109       rs780588354       rs780686701       rs780727853       rs780772704       rs780817112       rs780876286       rs780940391       rs781159711       rs781160640       rs781194810       rs781250784       rs781282989       rs781307821       rs781337368       rs781342104       rs781461835       rs781591069       rs781671723       rs781712986      

SREBF1基因在不同组织中的表达:    [UniProt]

基因在不同组织中的表达图
正向引物序列
正向引物Tm值
反向引物序列
反向引物Tm值
rank
CCAGTCTTTGAGGACAGCA
60
CTATGGTAGACGCTGGTGG
60
AACACAGCAACCAGAAACTC
59
CCAGATCCTTCAGAGATTTGC
59
TGTTCCTACATGAGGCCAC
59
CATCCATCAGCTCCTTTGC
59
ACATATCCAGCCTTTACTCCT
58
AGATCCTTCAGAGATTCTGTG
57
AACACAGCAACCAGAAACTC
59
CCAGATCCTTCAGAGATTTGC
59
TTTCTGACACGCTTCTTCCT
60
CATCCACGAAGAAACGGTG
59
CTTTCGAAGACATGCTTCAG
57
CTGTGACTGTCAGTAGCTG
57
TATTTGACCCACCCTATGCT
59
TGACTGTCAGTAGCTGCTG
59
TGACCATCTGTGAGAAGGC
59
CACAAGAAGCAGGTCACAC
59
CTTCTCTACAGGAAGCCCTC
59
GTGACTGTCAGTAGCTGCT
59
转录因子
影响类型
PubMed链接
ACACB
Unknown
ACLY
Activation
APOA5
Repression
APOA5
Unknown
AR
Unknown
BCL2L1
Repression
CAV1
Repression
CETP
Unknown
CIC
Unknown
FABP6
Unknown

SREBF1基因(以及对应的蛋白质)的细胞分布位置:

[UniProt]     [GenomeNet]

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • 溶酶体
  • 内涵体
  • 细胞核
  • 细胞质
  • 液泡
  • 细胞膜
  • 细胞外基质
  • 内质网
  • 线粒体
  • 高尔基体
  • 细胞骨架

SREBF1基因的本体(GO)信息:

GO库代码
对应的蛋白质
来源代码
GO:0046983
B5MD58(UniProtKB)
IEA
GO:0046983
F6V242(UniProtKB)
IEA
GO:0000122
P36956(UniProtKB)
IEA
GO:0000139
P36956(UniProtKB)
TAS
GO:0000139
P36956(UniProtKB)
TAS
GO:0000978
P36956(UniProtKB)
IEA
GO:0000978
P36956(UniProtKB)
IEA
GO:0001077
P36956(UniProtKB)
IEA
GO:0003062
P36956(UniProtKB)
IEA
GO:0003677
P36956(UniProtKB)
ISS
GO:0003682
P36956(UniProtKB)
IEA
GO:0003682
P36956(UniProtKB)
IEA
GO:0003700
P36956(UniProtKB)
IDA
GO:0005515
P36956(UniProtKB)
IPI
GO:0005515
P36956(UniProtKB)
IPI
GO:0005515
P36956(UniProtKB)
IPI
GO:0005515
P36956(UniProtKB)
IPI
GO:0005634
P36956(UniProtKB)
IDA
GO:0005634
P36956(UniProtKB)
IDA
GO:0005635
P36956(UniProtKB)
TAS
GO:0005654
P36956(UniProtKB)
TAS
GO:0005654
P36956(UniProtKB)
TAS
GO:0005654
P36956(UniProtKB)
TAS
GO:0005654
P36956(UniProtKB)
TAS
GO:0005654
P36956(UniProtKB)
TAS
GO:0005654
P36956(UniProtKB)
TAS
GO:0005654
P36956(UniProtKB)
TAS
GO:0005654
P36956(UniProtKB)
TAS
GO:0005654
P36956(UniProtKB)
TAS
GO:0005654
P36956(UniProtKB)
TAS
GO:0005654
P36956(UniProtKB)
TAS
GO:0005654
P36956(UniProtKB)
TAS
GO:0005654
P36956(UniProtKB)
TAS
GO:0005654
P36956(UniProtKB)
TAS
GO:0005654
P36956(UniProtKB)
TAS
GO:0005654
P36956(UniProtKB)
TAS
GO:0005654
P36956(UniProtKB)
TAS
GO:0005654
P36956(UniProtKB)
TAS
GO:0005654
P36956(UniProtKB)
TAS
GO:0005654
P36956(UniProtKB)
TAS
GO:0005654
P36956(UniProtKB)
TAS
GO:0005654
P36956(UniProtKB)
TAS
GO:0005654
P36956(UniProtKB)
TAS
GO:0005654
P36956(UniProtKB)
TAS
GO:0005654
P36956(UniProtKB)
TAS
GO:0005654
P36956(UniProtKB)
TAS
GO:0005654
P36956(UniProtKB)
TAS
GO:0005654
P36956(UniProtKB)
TAS
GO:0005654
P36956(UniProtKB)
TAS
GO:0005654
P36956(UniProtKB)
TAS
GO:0005654
P36956(UniProtKB)
TAS
GO:0005654
P36956(UniProtKB)
TAS
GO:0005654
P36956(UniProtKB)
TAS
GO:0005654
P36956(UniProtKB)
TAS
GO:0005654
P36956(UniProtKB)
TAS
GO:0005654
P36956(UniProtKB)
TAS
GO:0005654
P36956(UniProtKB)
TAS
GO:0005654
P36956(UniProtKB)
TAS
GO:0005654
P36956(UniProtKB)
TAS
GO:0005737
P36956(UniProtKB)
ISS
GO:0005783
P36956(UniProtKB)
IDA
GO:0005789
P36956(UniProtKB)
TAS
GO:0005789
P36956(UniProtKB)
TAS
GO:0005829
P36956(UniProtKB)
TAS
GO:0005829
P36956(UniProtKB)
TAS
GO:0005829
P36956(UniProtKB)
TAS
GO:0005829
P36956(UniProtKB)
TAS
GO:0006357
P36956(UniProtKB)
TAS
GO:0006629
P36956(UniProtKB)
TAS
GO:0007568
P36956(UniProtKB)
IEA
GO:0007623
P36956(UniProtKB)
TAS
GO:0008203
P36956(UniProtKB)
IEA
GO:0008286
P36956(UniProtKB)
IEA
GO:0008610
P36956(UniProtKB)
ISS
GO:0009267
P36956(UniProtKB)
ISS
GO:0009749
P36956(UniProtKB)
IEA
GO:0010867
P36956(UniProtKB)
ISS
GO:0012507
P36956(UniProtKB)
IEA
GO:0016021
P36956(UniProtKB)
IEA
GO:0019217
P36956(UniProtKB)
IEA
GO:0019901
P36956(UniProtKB)
IEA
GO:0030324
P36956(UniProtKB)
IEA
GO:0031065
P36956(UniProtKB)
IEA
GO:0031647
P36956(UniProtKB)
IMP
GO:0032094
P36956(UniProtKB)
IEA
GO:0032403
P36956(UniProtKB)
IEA
GO:0032526
P36956(UniProtKB)
IEA
GO:0032570
P36956(UniProtKB)
IEA
GO:0032810
P36956(UniProtKB)
IDA
GO:0033762
P36956(UniProtKB)
IEA
GO:0042493
P36956(UniProtKB)
IEA
GO:0042789
P36956(UniProtKB)
IEA
GO:0043234
P36956(UniProtKB)
IEA
GO:0045444
P36956(UniProtKB)
IEA
GO:0045542
P36956(UniProtKB)
IEA
GO:0045944
P36956(UniProtKB)
IEA
GO:0045944
P36956(UniProtKB)
IEA
GO:0045944
P36956(UniProtKB)
IDA
GO:0046676
P36956(UniProtKB)
IEA
GO:0046983
P36956(UniProtKB)
IEA
GO:0051591
P36956(UniProtKB)
IEA
GO:0071398
P36956(UniProtKB)
IEA
GO:1903146
P36956(UniProtKB)
IMP
GO:1903214
P36956(UniProtKB)
IMP
GO:0046983
X6RBE4(UniProtKB)
IEA
基因与其他基因之间的相互作用关系图
序号 作用方式 资源库来源/分值 基因名称 基因名称

可能调控SREBF1基因的相关microRNA:     


通路基因列表
疾病名称 关系值 NofPmids NofSnps 来源
疾病名称 关系值 NofPmids NofSnps 来源
Diabetes Mellitus, Experimental 0.2 3 0 CTD_human_RGD
Insulin Resistance 0.2 2 0 CTD_human_RGD
Obesity 0.13062984 16 0 BeFree_CTD_human_GAD
Fatty Liver 0.130063212 20 0 BeFree_CTD_human_LHGDN
Liver carcinoma 0.124624443 8 0 BeFree_CTD_human_LHGDN
Parkinson Disease 0.122638474 2 1 BeFree_GAD_GWASCAT
Kidney Failure, Chronic 0.122367032 2 0 CTD_human_GAD
Non-alcoholic Fatty Liver Disease 0.122171535 9 0 BeFree_CTD_human
Diabetes Mellitus, Non-Insulin-Dependent 0.09482102 15 2 BeFree_GAD_RGD
Hypercholesterolemia 0.08973957 6 0 BeFree_GAD_RGD
Diabetic Nephropathy 0.08 1 0 RGD
Diabetic Neuropathies 0.08 1 0 RGD
Fetal Growth Retardation 0.08 1 0 RGD
Kidney Diseases 0.08 1 0 RGD
Lipoidosis 0.08 1 0 RGD
Atherosclerosis 0.00554839 5 0 BeFree_GAD
Prostatic Neoplasms 0.0054487 2 0 LHGDN
Alzheimer's Disease 0.004734064 2 0 GAD
Dyslipidemias 0.004353001 6 2 BeFree_LHGDN
Malignant neoplasm of breast 0.003995683 6 0 BeFree_GAD
Metabolic Diseases 0.003810118 4 0 BeFree_LHGDN
Metabolic Syndrome X 0.003724241 6 0 BeFree_GAD
Mammary Neoplasms 0.002995792 2 0 BeFree_LHGDN
Steatohepatitis 0.002985861 11 0 BeFree
Coronary heart disease 0.002909916 3 1 BeFree_GAD
Hyperlipidemia 0.002909916 3 0 BeFree_GAD
Schizophrenia 0.002909916 2 1 BeFree_GAD
Anoxia 0.00272435 1 0 LHGDN
Hepatitis C 0.00272435 1 0 LHGDN
Hypertensive disease 0.00272435 1 0 LHGDN
Hypertriglyceridemia 0.00272435 1 0 LHGDN
Bone necrosis 0.00272435 1 0 LHGDN
Coronary Artery Disease 0.00272435 1 0 LHGDN
Diabetes Mellitus 0.002714419 10 0 BeFree
Dementia 0.002638474 1 0 BeFree_GAD
Femur Head Necrosis 0.002367032 1 0 GAD
Weight Gain 0.002367032 1 0 GAD
Weight Gain Adverse Event 0.002367032 1 0 GAD
Diabetes 0.002171535 8 0 BeFree
Malignant neoplasm of prostate 0.001628651 6 0 BeFree
Prostate carcinoma 0.001628651 6 0 BeFree
Breast Carcinoma 0.001628651 6 0 BeFree
Liver neoplasms 0.001085767 4 0 BeFree
Arteriosclerosis 0.000814326 3 0 BeFree
Malignant neoplasm of endometrium 0.000814326 3 0 BeFree
Hepatitis B 0.000814326 3 0 BeFree
Hyperinsulinism 0.000814326 3 0 BeFree
Lipodystrophy 0.000814326 3 0 BeFree
Familial partial lipodystrophy 0.000814326 3 1 BeFree
Endometrial Carcinoma 0.000814326 3 0 BeFree
Uterine Corpus Cancer 0.000814326 3 0 BeFree
Coronary Arteriosclerosis 0.000542884 2 1 BeFree
Endometrial Neoplasms 0.000542884 2 0 BeFree
Fatty Liver, Alcoholic 0.000542884 2 0 BeFree
Glioblastoma 0.000542884 2 0 BeFree
liposarcoma 0.000542884 2 0 BeFree
Tumor Progression 0.000542884 2 0 BeFree
Microvascular Angina 0.000542884 2 0 BeFree
Aortic Valve Insufficiency 0.000271442 1 0 BeFree
Aortic Valve Stenosis 0.000271442 1 0 BeFree
Noninfiltrating Intraductal Carcinoma 0.000271442 1 0 BeFree
Colorectal Carcinoma 0.000271442 1 0 BeFree
Presenile dementia 0.000271442 1 0 BeFree
Diabetes Mellitus, Insulin-Dependent 0.000271442 1 0 BeFree
Hepatomegaly 0.000271442 1 0 BeFree
HIV Infections 0.000271442 1 0 BeFree
Hyperglycemia 0.000271442 1 1 BeFree
Hypoglycemia 0.000271442 1 0 BeFree
Ketosis 0.000271442 1 1 BeFree
Progeria 0.000271442 1 1 BeFree
Kidney Failure 0.000271442 1 0 BeFree
B-Cell Lymphomas 0.000271442 1 0 BeFree
Hepatocellular Adenoma 0.000271442 1 0 BeFree
Acquired partial lipodystrophy 0.000271442 1 0 BeFree
Pancreatic carcinoma 0.000271442 1 0 BeFree
Fibrosis, Liver 0.000271442 1 0 BeFree
Malignant neoplasm of pancreas 0.000271442 1 0 BeFree
Muscular Dystrophy, Emery-Dreifuss 0.000271442 1 0 BeFree
Overweight 0.000271442 1 0 BeFree
Carcinogenesis 0.000271442 1 0 BeFree
Diabetic peripheral neuropathy 0.000271442 1 0 BeFree
Overnutrition 0.000271442 1 0 BeFree
Lipoatrophy 0.000271442 1 0 BeFree
Colorectal Cancer 0.000271442 1 0 BeFree
Trichothiodystrophy Syndromes 0.000271442 1 0 BeFree
Obesity, Visceral 0.000271442 1 0 BeFree
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