CFB(complement factor B)

基因简称(symbol)
    [HGNC]     [GeneCards]     [NCBI]
基因种类(locus group)
同源简称(alias symbol)
基因家族代码(gene_family_id)
    [HGNC]     [GenScript]
omim代码
entrez码
    [Vega]
vega基因码
ensembl基因码
    [Ensembl]
基因家族(gene family)
refseq数据库代号

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基因种类(locus_type)
基因名称状态(status)
location_sortable
同源基因名称(alias name)
基因名称批准使用时间(date_approved_reserved)
基因简称更名时间(date_symbol_changed)
基因名称更名时间(date_name_changed)
更新时间(date_modified)
ucsc码
ena
ccds数据码
uniprot数据码
pubmed代码
mgd码
rgd码
生命科学数据库(lsdb)
更新时间(date modified)
cosmic
mirbase
基因曾用简称(prev symbol)
基因曾用名称(prev name)
homeodb
cosmic
snornabase
bioparadigms slc
orphanet
假基因信息(pseudogeneorg)
horde id
merops
imgt
iuphar
kznf基因类别
mamit-trnadb
cd
LncRNA数据库
酶代码
中间纤维数据库

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6p21.33
基因染色体位置图

This gene encodes complement factor B, a component of the alternative pathway of complement activation. Factor B circulates in the blood as a single chain polypeptide. Upon activation of the alternative pathway, it is cleaved by complement factor D yielding the noncatalytic chain Ba and the catalytic subunit Bb. The active subunit Bb is a serine protease which associates with C3b to form the alternative pathway C3 convertase. Bb is involved in the proliferation of preactivated B lymphocytes, while Ba inhibits their proliferation. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. This cluster includes several genes involved in regulation of the immune reaction. Polymorphisms in this gene are associated with a reduced risk of age-related macular degeneration. The polyadenylation site of this gene is 421 bp from the 5' end of the gene for complement component 2. [provided by RefSeq, Jul 2008]

[中文简述(自动翻译):]  这个基因编码补体因子B,补体激活旁路途径的组分。因子B循环在血液中作为单链多肽。在替代途径的活化,它是由补体因子D裂解得到的非催化链Ba和催化亚基了Bb。活性亚基了Bb是丝氨酸蛋白酶,其与C3b的关联,以形成所述旁路途径C3转化。 BB参与预活化B淋巴细胞的增殖,而巴抑制其增殖。该基因定位于主要组织相容性复合体(MHC)类第三区域上6号染色体此群包括参与免疫反应的调节的几个基因。在这种基因多态性与年龄相关性黄斑变性的风险降低相关。该基因的聚腺苷酸化位点是从基因补体成分2的5‘端421碱基[通过的RefSeq,2008年7月提供]

CFB基因的碱基序列:[NCBI]
CFB基因的碱基突变:           显示全部snp
rs490835       rs4151648       rs4151666       rs9332730       rs11962289       rs34191899       rs36221133       rs45507391       rs72842444       rs139381609       rs141487807       rs143856440       rs145050210       rs146067615       rs147553278       rs149046227       rs150878060       rs183783980       rs193266718       rs200084119       rs200848760       rs201711512       rs201806170       rs368924961       rs369913423       rs370161918       rs370903470       rs371890710       rs373050754       rs374481091       rs374559513       rs375747855       rs375966724       rs376984495       rs377223802       rs527934096       rs531964680      
rs533333936       rs537649951       rs539408662       rs543080402       rs543316444       rs545115019       rs549709427       rs551464241       rs554264142       rs557513386       rs561595766       rs567255004       rs572328228       rs573094376       rs573470308       rs573509224       rs577320124       rs577779715       rs745625697       rs745667956       rs745995611       rs746085842       rs746257765       rs747042729       rs747480747       rs747529495       rs747655704       rs747684994       rs747936346       rs748333871       rs748385135       rs748834688       rs748953575       rs749196268       rs749249171       rs749532617       rs750264218       rs750960528       rs751105400       rs751164193       rs752364862       rs753052576       rs753105653       rs753626068       rs754142470       rs754270238       rs754328096       rs754558727       rs754649041       rs754655073       rs754774682       rs755370842       rs755422167       rs755869741       rs756513158       rs756703324       rs757160031       rs757311436       rs757893144       rs757928337       rs757959803       rs759345173       rs759520197       rs759782248       rs759839046       rs760072899       rs761863663       rs761941500       rs762234843       rs762630508       rs763044466       rs763268467       rs763269449       rs764248742       rs764904493       rs765091654       rs765244613       rs765488273       rs765593901       rs765716843       rs766101098       rs766168293       rs766290172       rs766749899       rs766775381       rs767147507       rs768010079       rs768179709       rs768592636       rs768645892       rs768757664       rs768915928       rs769490482       rs769679098       rs769958879       rs770223852       rs770364020       rs770899176       rs771797450       rs772164562       rs772267694       rs772507515       rs772827459       rs773111671       rs773857004       rs774178157       rs774346610       rs774349567       rs774429190       rs774473503       rs775409075       rs775490853       rs776056146       rs776584975       rs777096995       rs777423236       rs777972972       rs778610492       rs779079998       rs779656538       rs779777584       rs780258553       rs780284051       rs780535780       rs780808334       rs781171982       rs781758918       rs11392       rs11392       rs11392       rs11392       rs11392       rs11392       rs12614       rs512559       rs512559       rs512559       rs512559       rs512559       rs512559       rs522162       rs522162       rs522162       rs522162       rs522162       rs522162       rs537160       rs537160       rs537160       rs537160       rs537160       rs537160       rs541862       rs541862       rs541862       rs541862       rs541862       rs541862       rs641153       rs760070       rs760070       rs760070       rs760070       rs760070       rs760070       rs1048709       rs1270942       rs1270942       rs1270942       rs1270942       rs1270942       rs1270942       rs2072633       rs2072633       rs2072633       rs2072633       rs2072633       rs2072633       rs2072634       rs2072634       rs2072634       rs2072634       rs2072634       rs2072634       rs3880457       rs3880457       rs3880457       rs3880457       rs3880457       rs3880457       rs4151650       rs4151651       rs4151651       rs4151651       rs4151651       rs4151651       rs4151651       rs4151652       rs4151652       rs4151652       rs4151652       rs4151652       rs4151652       rs4151653       rs4151653       rs4151653       rs4151653       rs4151653       rs4151653       rs4151654       rs4151654       rs4151654       rs4151654       rs4151654       rs4151654       rs4151655       rs4151655       rs4151655       rs4151655       rs4151655       rs4151655       rs4151656       rs4151656       rs4151656       rs4151656       rs4151656       rs4151656       rs4151657       rs4151657       rs4151657       rs4151657       rs4151657       rs4151657       rs4151658       rs4151658       rs4151658       rs4151658       rs4151658       rs4151658       rs4151659       rs4151659       rs4151659       rs4151659       rs4151659       rs4151659       rs4151660       rs4151660       rs4151660       rs4151660       rs4151660       rs4151660       rs4151661       rs4151661       rs4151661       rs4151661       rs4151661       rs4151661       rs4151662       rs4151662       rs4151662       rs4151662       rs4151662       rs4151662       rs4151667       rs4151668       rs4151669       rs4151670       rs4151670       rs4151670       rs4151670       rs4151670       rs4151670       rs4151671       rs4151671       rs4151671       rs4151671       rs4151671       rs4151671       rs4151672       rs4151672       rs4151672       rs4151672       rs4151672       rs4151672       rs11541541       rs11541541       rs11541541       rs11541541       rs11541541       rs11541541       rs11754061       rs13194698       rs17201431       rs17201431       rs17201431       rs17201431       rs17201431       rs17201431       rs28571956       rs28571956       rs28571956       rs28571956       rs28571956       rs28571956       rs45484591       rs45484591       rs45484591       rs45484591       rs45484591       rs45484591       rs45600936       rs45600936       rs45600936       rs45600936       rs45600936       rs45600936       rs111740650       rs111740650       rs111740650       rs111740650       rs111740650       rs111740650       rs111969243       rs112395152       rs112395152       rs112395152       rs112395152       rs112395152       rs112395152       rs112490433       rs112490433       rs112490433       rs112490433       rs112490433       rs112490433       rs112646781       rs112646781       rs112646781       rs112646781       rs112646781       rs112646781       rs112884342       rs112978345       rs113197809       rs113359665       rs113395424       rs113395424       rs113395424       rs113395424       rs113395424       rs113395424       rs113410938       rs113410938       rs113410938       rs113410938       rs113410938       rs113410938       rs113781686       rs113781686       rs113781686       rs113781686       rs113781686       rs113781686       rs113885316       rs113885316       rs113885316       rs113885316       rs113885316       rs113885316       rs115686284       rs115686284       rs115686284       rs115686284       rs115686284       rs115686284       rs116928087       rs116928087       rs116928087       rs116928087       rs116928087       rs116928087       rs117314762       rs117905900       rs117905900       rs117905900       rs117905900       rs117905900       rs117905900       rs138207668       rs138207668       rs138207668       rs138207668       rs138207668       rs138207668       rs138236643       rs139672857       rs139672857       rs139672857       rs139672857       rs139672857       rs139672857       rs140166479       rs140166479       rs140166479       rs140166479       rs140166479       rs140166479       rs140185216       rs140185216       rs140185216       rs140185216       rs140185216       rs140185216       rs140338493       rs140338493       rs140338493       rs140338493       rs140338493       rs140338493       rs140877943       rs140877943       rs140877943       rs140877943       rs140877943       rs140877943       rs141298291       rs141298291       rs141298291       rs141298291       rs141298291       rs141298291       rs141349956       rs141349956       rs141349956       rs141349956       rs141349956       rs141349956       rs141485126       rs141485126       rs141485126       rs141485126       rs141485126       rs141485126       rs141965248       rs141965248       rs141965248       rs141965248       rs141965248       rs141965248       rs141984066       rs141984066       rs141984066       rs141984066       rs141984066       rs141984066       rs142078214       rs142078214       rs142078214       rs142078214       rs142078214       rs142078214       rs142827661       rs143558190       rs143558190       rs143558190       rs143558190       rs143558190       rs143558190       rs143905510       rs143905510       rs143905510       rs143905510       rs143905510       rs143905510       rs144339757       rs144339757       rs144339757       rs144339757       rs144339757       rs144339757       rs144542933       rs144542933       rs144542933       rs144542933       rs144542933       rs144542933       rs144812066       rs144812066       rs144812066       rs144812066       rs144812066       rs144812066       rs145082719       rs145082719       rs145082719       rs145082719       rs145082719       rs145082719       rs146107486       rs146107486       rs146107486       rs146107486       rs146107486       rs146107486       rs146157298       rs146157298       rs146157298       rs146157298       rs146157298       rs146157298       rs146329167       rs146329167       rs146329167       rs146329167       rs146329167       rs146329167       rs146477718       rs146477718       rs146477718       rs146477718       rs146477718       rs146477718       rs146976271       rs146976271       rs146976271       rs146976271       rs146976271       rs146976271       rs147564718       rs147564718       rs147564718       rs147564718       rs147564718       rs147564718       rs147831298       rs147831298       rs147831298       rs147831298       rs147831298       rs147831298       rs148298609       rs148298609       rs148298609       rs148298609       rs148298609       rs148298609       rs148898364       rs148898364       rs148898364       rs148898364       rs148898364       rs148898364       rs149101394       rs149101394       rs149101394       rs149101394       rs149101394       rs149101394       rs149375424       rs149428147       rs149428147       rs149428147       rs149428147       rs149428147       rs149428147       rs149665489       rs149665489       rs149665489       rs149665489       rs149665489       rs149665489       rs149691793       rs149691793       rs149691793       rs149691793       rs149691793       rs149691793       rs149944420       rs149944420       rs149944420       rs149944420       rs149944420       rs149944420       rs150398964       rs150398964       rs150398964       rs150398964       rs150398964       rs150398964       rs150920440       rs150920440       rs150920440       rs150920440       rs150920440       rs150920440       rs151133501       rs151133501       rs151133501       rs151133501       rs151133501       rs151133501       rs151311489       rs151311489       rs151311489       rs151311489       rs151311489       rs151311489       rs180977520       rs180977520       rs180977520       rs180977520       rs180977520       rs180977520       rs181642526       rs182413121       rs183293697       rs183293697       rs183293697       rs183293697       rs183293697       rs183293697       rs183347669       rs183347669       rs183347669       rs183347669       rs183347669       rs183347669       rs185387260       rs185387260       rs185387260       rs185387260       rs185387260       rs185387260       rs186794325       rs188688680       rs188688680       rs188688680       rs188688680       rs188688680       rs188688680       rs188810089       rs190228111       rs191517059       rs191517059       rs191517059       rs191517059       rs191517059       rs191517059       rs191597562       rs191786290       rs191786290       rs191786290       rs191786290       rs191786290       rs191786290       rs199518433       rs199518433       rs199518433       rs199518433       rs199518433       rs199518433       rs199721960       rs199721960       rs199721960       rs199721960       rs199721960       rs199721960       rs199725026       rs199725026       rs199725026       rs199725026       rs199725026       rs199725026       rs199837122       rs199837122       rs199837122       rs199837122       rs199837122       rs199837122       rs199869435       rs199869435       rs199869435       rs199869435       rs199869435       rs199869435       rs199930185       rs199930185       rs199930185       rs199930185       rs199930185       rs199930185       rs200095748       rs200095748       rs200095748       rs200095748       rs200095748       rs200095748       rs200274027       rs200429452       rs200429452       rs200429452       rs200429452       rs200429452       rs200429452       rs200572096       rs200572096       rs200572096       rs200572096       rs200572096       rs200572096       rs200620135       rs200620135       rs200620135       rs200620135       rs200620135       rs200620135       rs200645483       rs200645483       rs200645483       rs200645483       rs200645483       rs200645483       rs200837114       rs200837114       rs200837114       rs200837114       rs200837114       rs200837114       rs200890358       rs200890358       rs200890358       rs200890358       rs200890358       rs200890358       rs200986170       rs200986170       rs200986170       rs200986170       rs200986170       rs200986170       rs201297029       rs201297029       rs201297029       rs201297029       rs201297029       rs201297029       rs201323211       rs201323211       rs201323211       rs201323211       rs201323211       rs201323211       rs201619743       rs201619743       rs201619743       rs201619743       rs201619743       rs201619743       rs201621618       rs201621618       rs201621618       rs201621618       rs201621618       rs201621618       rs201659953       rs201659953       rs201659953       rs201659953       rs201659953       rs201659953       rs201721955       rs201721955       rs201721955       rs201721955       rs201721955       rs201721955       rs201754399       rs201754399       rs201754399       rs201754399       rs201754399       rs201754399       rs201798809       rs201798809       rs201798809       rs201798809       rs201798809       rs201798809       rs202094896       rs202094896       rs202094896       rs202094896       rs202094896       rs202094896       rs202177308       rs202177308       rs202177308       rs202177308       rs202177308       rs202177308       rs267600966       rs267600966       rs267600966       rs267600966       rs267600966       rs267600966       rs367565892       rs367565892       rs367565892       rs367565892       rs367565892       rs367565892       rs367632429       rs367632429       rs367632429       rs367632429       rs367632429       rs367632429       rs367892230       rs368040394       rs368040394       rs368040394       rs368040394       rs368040394       rs368040394       rs368280020       rs368280020       rs368280020       rs368280020       rs368280020       rs368280020       rs368322312       rs368735114       rs368735114       rs368735114       rs368735114       rs368735114       rs368735114       rs368798794       rs368798794       rs368798794       rs368798794       rs368798794       rs368798794       rs368887089       rs368887089       rs368887089       rs368887089       rs368887089       rs368887089       rs369124455       rs369124455       rs369124455       rs369124455       rs369124455       rs369124455       rs369138652       rs369138652       rs369138652       rs369138652       rs369138652       rs369138652       rs369375749       rs369531605       rs369531605       rs369531605       rs369531605       rs369531605       rs369531605       rs369638886       rs369950240       rs369950240       rs369950240       rs369950240       rs369950240       rs369950240       rs370019559       rs370019559       rs370019559       rs370019559       rs370019559       rs370019559       rs370280134       rs370396376       rs370396376       rs370396376       rs370396376       rs370396376       rs370396376       rs370470408       rs370470408       rs370470408       rs370470408       rs370470408       rs370470408       rs371284328       rs371606935       rs371606935       rs371606935       rs371606935       rs371606935       rs371606935       rs371630862       rs371630862       rs371630862       rs371630862       rs371630862       rs371630862       rs372020657       rs372020657       rs372020657       rs372020657       rs372020657       rs372020657       rs372495348       rs372495348       rs372495348       rs372495348       rs372495348       rs372495348       rs372715938       rs372858061       rs373083604       rs373083604       rs373083604       rs373083604       rs373083604       rs373083604       rs373303149       rs373303149       rs373303149       rs373303149       rs373303149       rs373303149       rs373352081       rs373352081       rs373352081       rs373352081       rs373352081       rs373352081       rs373357787       rs373357787       rs373357787       rs373357787       rs373357787       rs373357787       rs373731176       rs373768934       rs373768934       rs373768934       rs373768934       rs373768934       rs373768934       rs373881565       rs373881565       rs373881565       rs373881565       rs373881565       rs373881565       rs373903391       rs373903391       rs373903391       rs373903391       rs373903391       rs373903391       rs374021908       rs374021908       rs374021908       rs374021908       rs374021908       rs374021908       rs374044253       rs374044253       rs374044253       rs374044253       rs374044253       rs374044253       rs374743359       rs374743359       rs374743359       rs374743359       rs374743359       rs374743359       rs375002216       rs375002216       rs375002216       rs375002216       rs375002216       rs375002216       rs375168705       rs375168705       rs375168705       rs375168705       rs375168705       rs375168705       rs375398883       rs375398883       rs375398883       rs375398883       rs375398883       rs375398883       rs375465156       rs375465156       rs375465156       rs375465156       rs375465156       rs375465156       rs375595024       rs375609671       rs375697443       rs375697443       rs375697443       rs375697443       rs375697443       rs375697443       rs375895797       rs375895797       rs375895797       rs375895797       rs375895797       rs375895797       rs375954337       rs375954337       rs375954337       rs375954337       rs375954337       rs375954337       rs376239039       rs376239039       rs376239039       rs376239039       rs376239039       rs376239039       rs376369135       rs376595836       rs376595836       rs376595836       rs376595836       rs376595836       rs376595836       rs376966975       rs376966975       rs376966975       rs376966975       rs376966975       rs376966975       rs377017229       rs377017229       rs377017229       rs377017229       rs377017229       rs377017229       rs377025675       rs377025675       rs377025675       rs377025675       rs377025675       rs377025675       rs377314775       rs377549343       rs377549343       rs377549343       rs377549343       rs377549343       rs377549343       rs377665947       rs377665947       rs377665947       rs377665947       rs377665947       rs377665947       rs398123065       rs398123065       rs398123065       rs398123065       rs398123065       rs398123065       rs527879781       rs527879781       rs527879781       rs527879781       rs527879781       rs527879781       rs527918458       rs527918458       rs527918458       rs527918458       rs527918458       rs527918458       rs528519983       rs528519983       rs528519983       rs528519983       rs528519983       rs528519983       rs528914009       rs528914009       rs528914009       rs528914009       rs528914009       rs528914009       rs529269825       rs529269825       rs529269825       rs529269825       rs529269825       rs529269825       rs530325253       rs530325253       rs530325253       rs530325253       rs530325253       rs530325253       rs531193414       rs531231240       rs532026092       rs532026092       rs532026092       rs532026092       rs532026092       rs532026092       rs534739758       rs534739758       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rs540248609       rs541260302       rs542146357       rs542146357       rs542146357       rs542146357       rs542146357       rs542146357       rs542289635       rs543157757       rs543157757       rs543157757       rs543157757       rs543157757       rs543157757       rs543445589       rs543445589       rs543445589       rs543445589       rs543445589       rs543445589       rs544693212       rs544693212       rs544693212       rs544693212       rs544693212       rs544693212       rs545348156       rs545348156       rs545348156       rs545348156       rs545348156       rs545348156       rs546699122       rs546699122       rs546699122       rs546699122       rs546699122       rs546699122       rs547384497       rs547384497       rs547384497       rs547384497       rs547384497       rs547384497       rs548679597       rs548880408       rs548880408       rs548880408       rs548880408       rs548880408       rs548880408       rs549753008       rs549753008       rs549753008       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rs557087009       rs557087009       rs557087009       rs557087009       rs557215267       rs557215267       rs557215267       rs557215267       rs557215267       rs557215267       rs558389604       rs558389604       rs558389604       rs558389604       rs558389604       rs558389604       rs558604744       rs558604744       rs558604744       rs558604744       rs558604744       rs558604744       rs558955656       rs558955656       rs558955656       rs558955656       rs558955656       rs558955656       rs558967629       rs559712838       rs559712838       rs559712838       rs559712838       rs559712838       rs559712838       rs559907014       rs559980890       rs560218488       rs560681248       rs560802683       rs560802683       rs560802683       rs560802683       rs560802683       rs560802683       rs561435164       rs561435164       rs561435164       rs561435164       rs561435164       rs561435164       rs561473312       rs561473312       rs561473312       rs561473312       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rs745756319       rs745756319       rs745766073       rs745794224       rs745821869       rs745821869       rs745821869       rs745821869       rs745821869       rs745821869       rs745854895       rs745854895       rs745854895       rs745854895       rs745854895       rs745854895       rs745920524       rs745920524       rs745920524       rs745920524       rs745920524       rs745920524       rs746105947       rs746202820       rs746306913       rs746306913       rs746306913       rs746306913       rs746306913       rs746306913       rs746437233       rs746437233       rs746437233       rs746437233       rs746437233       rs746437233       rs746619139       rs746619139       rs746619139       rs746619139       rs746619139       rs746619139       rs746804320       rs747017251       rs747114058       rs747114058       rs747114058       rs747114058       rs747114058       rs747114058       rs747121417       rs747121417       rs747121417       rs747121417       rs747121417       rs747121417       rs747193442       rs747193442       rs747193442       rs747193442       rs747193442       rs747193442       rs747359956       rs747404399       rs747404399       rs747404399       rs747404399       rs747404399       rs747404399       rs747474569       rs747605859       rs747605859       rs747605859       rs747605859       rs747605859       rs747605859       rs747687430       rs747687430       rs747687430       rs747687430       rs747687430       rs747687430       rs747698116       rs747698116       rs747698116       rs747698116       rs747698116       rs747698116       rs747955294       rs747955294       rs747955294       rs747955294       rs747955294       rs747955294       rs748008737       rs748008737       rs748008737       rs748008737       rs748008737       rs748008737       rs748063426       rs748063426       rs748063426       rs748063426       rs748063426       rs748063426       rs748150244       rs748150244       rs748150244       rs748150244       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rs775184506       rs775184506       rs775240109       rs775240109       rs775240109       rs775240109       rs775240109       rs775240109       rs775307617       rs775307617       rs775307617       rs775307617       rs775307617       rs775307617       rs775365194       rs775365194       rs775365194       rs775365194       rs775365194       rs775365194       rs775416425       rs775416425       rs775416425       rs775416425       rs775416425       rs775416425       rs775697027       rs775716041       rs775716041       rs775716041       rs775716041       rs775716041       rs775716041       rs775872016       rs775872016       rs775872016       rs775872016       rs775872016       rs775872016       rs776048261       rs776048261       rs776048261       rs776048261       rs776048261       rs776048261       rs776095395       rs776095395       rs776095395       rs776095395       rs776095395       rs776095395       rs776382264       rs776382264       rs776382264       rs776382264       rs776382264       rs776382264       rs776433225       rs776433225       rs776433225       rs776433225       rs776433225       rs776433225       rs776436917       rs776436917       rs776436917       rs776436917       rs776436917       rs776436917       rs776467742       rs776541109       rs776691231       rs776691231       rs776691231       rs776691231       rs776691231       rs776691231       rs776825572       rs776825572       rs776825572       rs776825572       rs776825572       rs776825572       rs776912216       rs776912216       rs776912216       rs776912216       rs776912216       rs776912216       rs776938857       rs776964009       rs776964009       rs776964009       rs776964009       rs776964009       rs776964009       rs777042139       rs777042139       rs777042139       rs777042139       rs777042139       rs777042139       rs777149548       rs777149548       rs777149548       rs777149548       rs777149548       rs777149548       rs777256212       rs777256212       rs777256212       rs777256212       rs777256212       rs777256212       rs777311237       rs777311237       rs777311237       rs777311237       rs777311237       rs777311237       rs777346310       rs777365717       rs777430403       rs777430403       rs777430403       rs777430403       rs777430403       rs777430403       rs777468711       rs777468711       rs777468711       rs777468711       rs777468711       rs777468711       rs777499237       rs777516147       rs777516147       rs777516147       rs777516147       rs777516147       rs777516147       rs777571264       rs777754697       rs777754697       rs777754697       rs777754697       rs777754697       rs777754697       rs777788034       rs777788034       rs777788034       rs777788034       rs777788034       rs777788034       rs777849105       rs777877647       rs777877647       rs777877647       rs777877647       rs777877647       rs777877647       rs777891193       rs777891193       rs777891193       rs777891193       rs777891193       rs777891193       rs777991837       rs777991837       rs777991837       rs777991837       rs777991837       rs777991837       rs778130213       rs778130213       rs778130213       rs778130213       rs778130213       rs778130213       rs778343673       rs778396739       rs778433736       rs778433736       rs778433736       rs778433736       rs778433736       rs778433736       rs778556793       rs778556793       rs778556793       rs778556793       rs778556793       rs778556793       rs778616450       rs778616450       rs778616450       rs778616450       rs778616450       rs778616450       rs778702824       rs778702824       rs778702824       rs778702824       rs778702824       rs778702824       rs778844695       rs778844695       rs778844695       rs778844695       rs778844695       rs778844695       rs778914840       rs778914840       rs778914840       rs778914840       rs778914840       rs778914840       rs778982624       rs778982624       rs778982624       rs778982624       rs778982624       rs778982624       rs779015009       rs779015009       rs779015009       rs779015009       rs779015009       rs779015009       rs779024832       rs779078053       rs779327325       rs779327325       rs779327325       rs779327325       rs779327325       rs779327325       rs779415434       rs779415434       rs779415434       rs779415434       rs779415434       rs779415434       rs779468736       rs779468736       rs779468736       rs779468736       rs779468736       rs779468736       rs779470631       rs779470631       rs779470631       rs779470631       rs779470631       rs779470631       rs779604940       rs779648102       rs779648102       rs779648102       rs779648102       rs779648102       rs779648102       rs779672308       rs779672308       rs779672308       rs779672308       rs779672308       rs779672308       rs779727122       rs779782561       rs779782561       rs779782561       rs779782561       rs779782561       rs779782561       rs779915932       rs779915932       rs779915932       rs779915932       rs779915932       rs779915932       rs779931165       rs779931165       rs779931165       rs779931165       rs779931165       rs779931165       rs779981834       rs779981834       rs779981834       rs779981834       rs779981834       rs779981834       rs780051608       rs780116525       rs780116525       rs780116525       rs780116525       rs780116525       rs780116525       rs780217821       rs780457366       rs780457366       rs780457366       rs780457366       rs780457366       rs780457366       rs780506384       rs780506384       rs780506384       rs780506384       rs780506384       rs780506384       rs780561436       rs780561436       rs780561436       rs780561436       rs780561436       rs780561436       rs780616213       rs780616213       rs780616213       rs780616213       rs780616213       rs780616213       rs780787668       rs780912393       rs781127297       rs781127297       rs781127297       rs781127297       rs781127297       rs781127297       rs781135926       rs781177133       rs781177133       rs781177133       rs781177133       rs781177133       rs781177133       rs781245821       rs781245821       rs781245821       rs781245821       rs781245821       rs781245821       rs781302176       rs781302176       rs781302176       rs781302176       rs781302176       rs781302176       rs781351514       rs781371742       rs781371742       rs781371742       rs781371742       rs781371742       rs781371742       rs781424814       rs781424814       rs781424814       rs781424814       rs781424814       rs781424814       rs781563498       rs781563498       rs781563498       rs781563498       rs781563498       rs781563498       rs781652229       rs781652229       rs781652229       rs781652229       rs781652229       rs781652229       rs781667620       rs781735808       rs781735808       rs781735808       rs781735808       rs781735808       rs781735808      

CFB基因在不同组织中的表达:    [UniProt]

基因在不同组织中的表达图
正向引物序列
正向引物Tm值
反向引物序列
反向引物Tm值
rank
AGTACCGCCTTGAAGACAG
59
ATGAAGGAGTCTTGGCAGG
59
TAATGCAGACTGGGTCACG
60
CCCTGACTTCAACTTGTGG
58
CTCATGACTGATGGATTGCAC
60
GCCAATGTATAGCAAGTCCC
59
TCTACCAAATGATCGGAGGG
59
TCCCATTAATGTTGTAGTTGGG
59
TTCTACCAAATGATCGGAGG
57
CCCATTAATGTTGTAGTTGGG
57
ATGGTTTGGGAACACAGGA
59
CTTTGAAGGGCGAATGACTG
60
ATACTTGCAGAGGTGATTCTG
58
TAGGAAAGGGAGGACTCAC
58
GAGGATTATCTGGATGTCTATGTG
59
TTTCTTGGAAGCCAAAGCA
58
TTTCTACCAAATGATCGGAGG
58
CCCATTAATGTTGTAGTTGGG
57
AAGACAATGAGCAACATGTG
57
GGCTTTCATCGATCATTTGG
58
      尚未收录相关数据

CFB基因(以及对应的蛋白质)的细胞分布位置:

[UniProt]     [GenomeNet]

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • 溶酶体
  • 内涵体
  • 细胞核
  • 细胞质
  • 液泡
  • 细胞膜
  • 细胞外基质
  • 内质网
  • 线粒体
  • 高尔基体
  • 细胞骨架

CFB基因的本体(GO)信息:

GO库代码
对应的蛋白质
来源代码
GO:0004252
A0A0G2JH38(UniProtKB)
IEA
GO:0005576
A0A0G2JH38(UniProtKB)
IEA
GO:0006508
A0A0G2JH38(UniProtKB)
IEA
GO:0006956
A0A0G2JH38(UniProtKB)
IEA
GO:0004252
H7C526(UniProtKB)
IEA
GO:0006508
H7C526(UniProtKB)
IEA
GO:0004252
H7C5H1(UniProtKB)
IEA
GO:0006508
H7C5H1(UniProtKB)
IEA
GO:0001848
P00751(UniProtKB)
TAS
GO:0004252
P00751(UniProtKB)
TAS
GO:0004252
P00751(UniProtKB)
TAS
GO:0004252
P00751(UniProtKB)
TAS
GO:0005576
P00751(UniProtKB)
TAS
GO:0005576
P00751(UniProtKB)
TAS
GO:0005576
P00751(UniProtKB)
TAS
GO:0005576
P00751(UniProtKB)
TAS
GO:0005576
P00751(UniProtKB)
TAS
GO:0005576
P00751(UniProtKB)
TAS
GO:0005576
P00751(UniProtKB)
TAS
GO:0005576
P00751(UniProtKB)
TAS
GO:0005576
P00751(UniProtKB)
TAS
GO:0005576
P00751(UniProtKB)
TAS
GO:0005615
P00751(UniProtKB)
IDA
GO:0005886
P00751(UniProtKB)
TAS
GO:0005886
P00751(UniProtKB)
TAS
GO:0005886
P00751(UniProtKB)
TAS
GO:0005886
P00751(UniProtKB)
TAS
GO:0005886
P00751(UniProtKB)
TAS
GO:0005886
P00751(UniProtKB)
TAS
GO:0005886
P00751(UniProtKB)
TAS
GO:0005886
P00751(UniProtKB)
TAS
GO:0005886
P00751(UniProtKB)
TAS
GO:0005886
P00751(UniProtKB)
TAS
GO:0005886
P00751(UniProtKB)
TAS
GO:0005886
P00751(UniProtKB)
TAS
GO:0006508
P00751(UniProtKB)
IEA
GO:0006956
P00751(UniProtKB)
TAS
GO:0006957
P00751(UniProtKB)
NAS
GO:0006957
P00751(UniProtKB)
TAS
GO:0030449
P00751(UniProtKB)
TAS
GO:0070062
P00751(UniProtKB)
IDA
GO:0070062
P00751(UniProtKB)
IDA
GO:0072562
P00751(UniProtKB)
IDA
基因与其他基因之间的相互作用关系图
序号 作用方式 资源库来源/分值 基因名称 基因名称

可能调控CFB基因的相关microRNA:     


通路基因列表
疾病名称 关系值 NofPmids NofSnps 来源
疾病名称 关系值 NofPmids NofSnps 来源
HEMOLYTIC UREMIC SYNDROME, ATYPICAL, SUSCEPTIBILITY TO, 4 0.36 2 2 CLINVAR_ORPHANET_UNIPROT
Age related macular degeneration 0.319044595 56 21 BeFree_CTD_human_GAD_GWASCAT_LHGDN
Lupus Erythematosus, Systemic 0.134202192 5 1 CTD_human_GAD
Atypical Hemolytic Uremic Syndrome 0.121085767 4 0 BeFree_CTD_human
Ulcerative Colitis 0.120271442 2 1 BeFree_GWASCAT
Hepatitis B, Chronic 0.120271442 1 1 BeFree_GWASCAT
Myasthenia Gravis 0.12 1 0 CTD_human
Macular Degeneration, Age-Related, 1 0.12 0 0 CTD_human
MACULAR DEGENERATION, AGE-RELATED, 14 0.12 0 1 CLINVAR
COMPLEMENT FACTOR B DEFICIENCY 0.12 0 2 CLINVAR
Diabetes Mellitus, Insulin-Dependent 0.011639663 10 3 BeFree_GAD
Choroid Diseases 0.007101096 3 0 GAD
Peripheral Vascular Diseases 0.007101096 3 0 GAD
Alzheimer's Disease 0.005005506 3 0 BeFree_GAD
Hemolytic-Uremic Syndrome 0.005005506 3 0 BeFree_GAD
Multiple Sclerosis 0.004734064 2 1 GAD
Choroidal Neovascularization 0.004734064 2 0 GAD
Meningococcal Infections 0.00272435 1 0 LHGDN
Psoriasis 0.00272435 1 0 LHGDN
Premature Birth 0.00272435 1 0 LHGDN
Diabetes Mellitus, Non-Insulin-Dependent 0.002638474 2 0 BeFree_GAD
HIV Infections 0.002638474 2 0 BeFree_GAD
Retinal Diseases 0.002638474 2 0 BeFree_GAD
Geographic Atrophy 0.002638474 2 0 BeFree_GAD
Spontaneous abortion 0.002367032 1 0 GAD
Ataxia Telangiectasia 0.002367032 1 0 GAD
Choroiditis 0.002367032 1 0 GAD
Coronary heart disease 0.002367032 1 0 GAD
Mental Depression 0.002367032 1 0 GAD
Lymphoma, Non-Hodgkin 0.002367032 1 0 GAD
Parkinson Disease 0.002367032 1 0 GAD
Retinal Drusen 0.002367032 1 0 GAD
Low Vision 0.002367032 1 0 GAD
Rheumatoid Arthritis 0.001085767 4 0 BeFree
Macular degeneration 0.000814326 3 3 BeFree
Exudative age-related macular degeneration 0.000814326 3 0 BeFree
Diabetes 0.000542884 2 4 BeFree
Diabetes Mellitus 0.000542884 2 4 BeFree
Schizophrenia 0.000542884 2 0 BeFree
Drusen 0.000542884 2 1 BeFree
Autoimmune Diseases 0.000271442 1 0 BeFree
Crohn Disease 0.000271442 1 0 BeFree
Necrotizing Ulcerative Gingivitis 0.000271442 1 0 BeFree
Glomerulonephritis 0.000271442 1 0 BeFree
Inflammatory Bowel Diseases 0.000271442 1 0 BeFree
Kidney Failure, Acute 0.000271442 1 0 BeFree
Acute lymphocytic leukemia 0.000271442 1 0 BeFree
Malignant neoplasm of stomach 0.000271442 1 0 BeFree
Obesity 0.000271442 1 0 BeFree
Pyruvate Carboxylase Deficiency Disease 0.000271442 1 0 BeFree
Septicemia 0.000271442 1 0 BeFree
Anterior uveitis 0.000271442 1 0 BeFree
Pancreatitis, Chronic 0.000271442 1 0 BeFree
Sepsis 0.000271442 1 0 BeFree
Coinfection 0.000271442 1 0 BeFree
Carcinogenesis 0.000271442 1 0 BeFree
Bacterial sepsis 0.000271442 1 0 BeFree
Malignant neoplasm of gastrointestinal tract 0.000271442 1 0 BeFree
Stomach Carcinoma 0.000271442 1 0 BeFree
Acute anterior uveitis 0.000271442 1 0 BeFree
Pancreatic Ductal Adenocarcinoma 0.000271442 1 0 BeFree
Severe Sepsis 0.000271442 1 0 BeFree
Unspecified visual loss 0.000271442 1 0 BeFree
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