RIT1基因详情-基因数据库-基因云馆

RIT1(Ras-like without CAAX 1)

基因简称(symbol)

RIT1 [HGNC] [GeneCards] [NCBI]

基因种类(locus group)

protein-coding gene

同源简称(alias symbol)

RIBB|ROC1|MGC125864|MGC125865

基因家族代码(gene_family_id)

389 [HGNC] [GenScript]

omim代码

609591

entrez码

6016 [Vega]

vega基因码

OTTHUMG00000014104

ensembl基因码

ENSG00000143622 [Ensembl]

基因家族(gene family)

RAS type family GTPases

refseq数据库代号

NM_006912

更多...

基因种类(locus_type)

gene with protein product

基因名称状态(status)

Approved

location_sortable

01q21.2

同源基因名称(alias name)

Ric-like, expressed in many tissues|GTP-binding protein Roc1

基因名称批准使用时间(date_approved_reserved)

1996-08-28T00:00:00Z

基因简称更名时间(date_symbol_changed)

2002-09-13T00:00:00Z

基因名称更名时间(date_name_changed)

2002-09-11T00:00:00Z

更新时间(date_modified)

2014-11-19T00:00:00Z

ucsc码

uc031pqc.1

ena

AF084462

ccds数据码

CCDS1123|CCDS58037|CCDS58036

uniprot数据码

Q92963

pubmed代码

8824319|8918462

mgd码

MGI:108053

rgd码

RGD:1559874

生命科学数据库(lsdb)

更新时间(date modified)

2014-11-19T00:00:00Z

cosmic

RIT1

mirbase

基因曾用简称(prev symbol)

RIT

基因曾用名称(prev name)

Ric (Drosophila)-like, expressed in many tissues

homeodb

cosmic

RIT1

snornabase

bioparadigms slc

orphanet

358630

假基因信息(pseudogeneorg)

horde id

merops

imgt

iuphar

kznf基因类别

mamit-trnadb

cd

LncRNA数据库

酶代码

中间纤维数据库

收起

1q21.2

This gene encodes a member of a subfamily of Ras-related GTPases. The encoded protein is involved in regulating p38 MAPK-dependent signaling cascades related to cellular stress. This protein also cooperates with nerve growth factor to promote neuronal development and regeneration. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2012]

[中文简述(自动翻译):] 该基因编码的Ras相关GTP酶亚家族的一个成员。所编码的蛋白质是参与调节有关细胞应激p38蛋白依赖性信号级联。这种蛋白质也与神经生长因子的合作，促进神经元的发育和再生。选择性剪接结果在多个抄本变形。 [由RefSeq的，2012年2月提供]

OMIM数据库中对RIT1基因的介绍 Wikipedia数据库中对RIT1基因的介绍

RIT1基因的碱基序列：[NCBI]

RIT1基因的碱基突变：显示全部snp

rs708614 rs41264985 rs57810844 rs71628697 rs75009387 rs76644993 rs76903692 rs111951730 rs186541684 rs529516575 rs534301604 rs545495997 rs562026387 rs564079590 rs568161866 rs490498 rs493446 rs527113 rs536870 rs550092 rs605472 rs656247 rs656737 rs670523 rs822654 rs867548 rs867549 rs867550 rs1052185 rs1055184 rs1749409 rs1765274 rs1765275 rs1974259 rs2184935 rs2282301 rs2477545

rs3856261 rs5777961 rs6427293 rs7545308 rs10908484 rs11387126 rs11809798 rs12034512 rs12037177 rs12039137 rs12126842 rs12139710 rs12144175 rs12144993 rs12564928 rs12749206 rs13376362 rs16837089 rs34831194 rs34974790 rs59831983 rs59899087 rs66596684 rs66756214 rs71080738 rs71517801 rs74685839 rs75154294 rs76121330 rs76776594 rs78371663 rs78635036 rs78912184 rs79109024 rs79231760 rs79437610 rs80019356 rs80308596 rs111792190 rs112505242 rs112779972 rs112823580 rs113604216 rs113618684 rs114192875 rs115138670 rs115995005 rs116008346 rs116215287 rs116368781 rs116527832 rs116547449 rs116836973 rs117435431 rs117963129 rs137869219 rs137889217 rs138290726 rs138509537 rs139030958 rs139248572 rs139551600 rs139816890 rs140077956 rs140521111 rs140701211 rs140751929 rs141525708 rs141566906 rs142205470 rs142974413 rs143384959 rs143847768 rs143997364 rs144170253 rs144611612 rs144650250 rs145034964 rs145286724 rs145897907 rs146206377 rs147426122 rs147854631 rs147863686 rs148665588 rs148764677 rs149037274 rs149195005 rs149507481 rs150276092 rs150429473 rs150541909 rs151071626 rs181154689 rs181237993 rs181552460 rs181766596 rs181978604 rs182748403 rs182777908 rs182838493 rs183285600 rs183433501 rs183537697 rs184000984 rs184474082 rs184526262 rs184878276 rs185653845 rs185942596 rs186312427 rs186427960 rs186486271 rs186539561 rs186971159 rs187013577 rs187356197 rs187910789 rs188174077 rs188229331 rs188463470 rs189053803 rs189103524 rs189251247 rs189334206 rs189668119 rs189783622 rs189882158 rs190323643 rs190561226 rs190748168 rs190977688 rs191083901 rs191253501 rs191410245 rs191788979 rs192114811 rs192363719 rs192448173 rs192497685 rs192952048 rs192960301 rs199724271 rs199914900 rs200232506 rs200399012 rs200597833 rs201167229 rs201613012 rs201898950 rs367785615 rs367886540 rs368034116 rs368471795 rs368560843 rs369138238 rs369305380 rs369738767 rs370084945 rs370396152 rs370683922 rs370776643 rs371313977 rs371501810 rs371562683 rs372092063 rs372170139 rs372535175 rs373003493 rs374144813 rs374796711 rs375379708 rs375724784 rs375874988 rs376391961 rs376639749 rs377202288 rs377326705 rs397745289 rs397808743 rs398049612 rs483352822 rs527328449 rs527598541 rs527741406 rs527805202 rs527805298 rs528131189 rs528728324 rs528865548 rs528925441 rs528928455 rs529146132 rs529429988 rs529822769 rs529909393 rs530156680 rs530289439 rs530367075 rs530400697 rs530526533 rs531258940 rs532244854 rs532310086 rs533010827 rs533075000 rs533077003 rs533522602 rs533522873 rs533608441 rs534677905 rs534738846 rs534789053 rs534846374 rs535279973 rs535712913 rs535877877 rs536039439 rs536125080 rs536235641 rs536238745 rs536251266 rs536320780 rs536675302 rs536722245 rs537060228 rs537627155 rs537688710 rs537721320 rs537835500 rs538531940 rs538624309 rs538639616 rs538823235 rs538875793 rs539852726 rs540016055 rs540077950 rs540102421 rs540427520 rs540429325 rs541016621 rs541482565 rs541663359 rs542038133 rs542195615 rs542253536 rs542388356 rs542388856 rs543207786 rs543211600 rs543247518 rs543261817 rs543733345 rs543794551 rs543924727 rs544612997 rs544676394 rs544789160 rs544850624 rs545031201 rs545159465 rs545592476 rs545605014 rs546206979 rs546356253 rs546602712 rs546778635 rs546841760 rs546867498 rs546914969 rs547298339 rs547359349 rs548024400 rs548107558 rs548215994 rs548567581 rs548729062 rs549176174 rs549304281 rs549470674 rs549546069 rs549679324 rs550583484 rs550645403 rs550659434 rs550974807 rs551099445 rs551393972 rs551536699 rs551778089 rs551964173 rs552089940 rs552708028 rs552740200 rs553099179 rs553100496 rs553163312 rs553287973 rs554218263 rs554243333 rs554292923 rs554555050 rs555673177 rs555687772 rs555815081 rs556640708 rs556672651 rs556734176 rs556934396 rs557013903 rs557077012 rs557157373 rs557698816 rs558100301 rs558213998 rs558471836 rs558697359 rs559625219 rs560012416 rs560261115 rs560483943 rs560626067 rs560807420 rs560826701 rs561120844 rs561871878 rs562081492 rs562642078 rs562705538 rs563231684 rs563424124 rs563920078 rs564018962 rs564082349 rs564430959 rs564442841 rs564578432 rs564599200 rs565107424 rs566263821 rs566425148 rs567876773 rs567960713 rs568146920 rs568785728 rs568820064 rs568922271 rs569121652 rs569133806 rs569661142 rs570518965 rs570938677 rs571339160 rs571414261 rs571436720 rs571602570 rs571671627 rs571939405 rs572516676 rs572732588 rs572797151 rs573145854 rs573813074 rs573874231 rs573898453 rs573940729 rs574006035 rs574272154 rs574970215 rs575037540 rs575099680 rs575211595 rs575858185 rs575858514 rs576433986 rs576482764 rs576522765 rs576533588 rs576664566 rs577050310 rs577480696 rs577583246 rs577709122 rs577993491 rs730881012 rs730881013 rs745465435 rs745534608 rs745789701 rs745807905 rs746073428 rs746272715 rs746377503 rs746581657 rs746676661 rs746838618 rs747376042 rs747459574 rs748272466 rs748634085 rs748838734 rs749154341 rs749213571 rs749375792 rs749557422 rs749781421 rs750076057 rs750270294 rs750755911 rs751266005 rs751502424 rs751738914 rs751795576 rs752007040 rs752080344 rs752204910 rs752589507 rs752673936 rs753111645 rs753425443 rs753538357 rs753558565 rs754151345 rs754510314 rs754596127 rs754833053 rs755188426 rs755316223 rs755664065 rs755786992 rs756232487 rs756526089 rs756731122 rs757056888 rs757129389 rs757327468 rs757684037 rs758160580 rs758250608 rs758376355 rs758527352 rs758651076 rs758925029 rs759314326 rs759512736 rs760053864 rs760141559 rs760298603 rs760706554 rs760720573 rs760827833 rs760845441 rs761024934 rs761779370 rs761961883 rs762617630 rs762690705 rs762892205 rs763208084 rs763445246 rs763494925 rs763662054 rs763868802 rs764151643 rs764174304 rs764347644 rs764912034 rs765435035 rs765624804 rs765636979 rs766063111 rs766105622 rs766193814 rs766404944 rs766428438 rs766640740 rs766952004 rs767329996 rs767393761 rs767498196 rs767822483 rs768376601 rs768560072 rs768732106 rs768882363 rs769063568 rs769284221 rs769298435 rs769354873 rs769724664 rs770107359 rs770237120 rs770599407 rs770621094 rs770853133 rs771011997 rs771703451 rs771768320 rs772560836 rs772575179 rs772668542 rs772868643 rs772993915 rs773277945 rs773340979 rs773931858 rs774164177 rs774818471 rs775310783 rs775926859 rs775961212 rs776109027 rs776195492 rs776404635 rs776708681 rs777167776 rs777450446 rs777520196 rs777648382 rs778233462 rs778317389 rs778420487 rs778512169 rs778896290 rs778972674 rs779345018 rs779433647 rs779457410 rs779553169 rs779947152 rs780210314 rs780585553 rs781059933 rs781557110

RIT1基因在不同组织中的表达： [UniProt]

正向引物序列

正向引物Tm值

反向引物序列

反向引物Tm值

rank

TAAGACAGGTCACCAAGGA

58

GGTATGCAGCAGATGTCTC

58

TGCTTATAAGATCAGGATCCGT

59

TGTAAACTCTGCCTGTCCA

59

TGCTTATAAGATCAGGATCCG

57

GTAAACTCTGCCTGTCCAG

58

TAGGGAAGAGTGCCATGAC

59

GATCTGGCTTACCAATGGTG

59

GATGCTTATAAGATCAGGATCCG

59

TAAACTCTGCCTGTCCAGC

60

TGCTTATAAGATCAGGATCCGT

59

CTCTGCCTGCTATCCTGTC

60

GATGCTTATAAGATCAGGATCCG

59

TAAACTCTGCCTGTCCAGC

60

TGCTTATAAGATCAGGATCCGT

59

TGTAAACTCTGCCTGTCCA

59

TAGGGAAGAGTGCCATGAC

59

ATGATCTGGCTTACCAATGGT

60

GATGCTTATAAGATCAGGATCCG

59

CTCTGCCTGCTATCCTGTC

60

尚未收录相关数据

RIT1基因（以及对应的蛋白质）的细胞分布位置：

[UniProt] [GenomeNet]

溶酶体
内涵体
细胞核
细胞质
液泡
细胞膜
细胞外基质
内质网
线粒体
高尔基体
细胞骨架

RIT1基因的本体（GO）信息：

GO库代码

对应的蛋白质

来源代码

GO:0005515

Q92963(UniProtKB)

IPI

GO:0005516

Q92963(UniProtKB)

TAS

GO:0005525

Q92963(UniProtKB)

IEA

GO:0005622

Q92963(UniProtKB)

IEA

GO:0005622

Q92963(UniProtKB)

IEA

GO:0005886

Q92963(UniProtKB)

IEA

GO:0007165

Q92963(UniProtKB)

TAS

GO:0007265

Q92963(UniProtKB)

IDA

GO:0005525

V9GY29(UniProtKB)

IEA

GO:0005622

V9GY29(UniProtKB)

IEA

GO:0007264

V9GY29(UniProtKB)

IEA

GO:0016020

V9GY29(UniProtKB)

IEA

GO:0005525

V9GYC3(UniProtKB)

IEA

GO:0005622

V9GYC3(UniProtKB)

IEA

GO:0007264

V9GYC3(UniProtKB)

IEA

GO:0016020

V9GYC3(UniProtKB)

IEA

序号	作用方式	资源库来源/分值	基因名称	基因名称

可能调控RIT1基因的相关microRNA：

hsa-miR-218 hsa-miR-340

通路基因列表

疾病名称

关系值

NofPmids

NofSnps

来源

疾病名称	关系值	NofPmids	NofSnps	来源
NOONAN SYNDROME 8	0.24	1	2	CLINVAR_UNIPROT
Noonan Syndrome	0.120542884	2	0	BeFree_ORPHANET
Inflammatory Bowel Diseases	0.12	1	1	GWASCAT
Liver carcinoma	0.00272435	1	0	LHGDN
Conduct Disorder	0.002367032	1	1	GAD
Congenital Heart Defects	0.000271442	1	0	BeFree
leukemia	0.000271442	1	0	BeFree
Adenocarcinoma of lung (disorder)	0.000271442	1	0	BeFree
Liver and Intrahepatic Biliary Tract Carcinoma	0.000271442	1	0	BeFree
Malignant neoplasm of liver	0.000271442	1	0	BeFree
Craniofacial Abnormalities	0.000271442	1	0	BeFree