HES1(hes family bHLH transcription factor 1)
基因简称(symbol)
基因种类(locus group)
同源简称(alias symbol)
基因家族代码(gene_family_id)
omim代码
entrez码
vega基因码
ensembl基因码
基因家族(gene family)
refseq数据库代号
更多...
基因种类(locus_type)
基因名称状态(status)
location_sortable
同源基因名称(alias name)
基因名称批准使用时间(date_approved_reserved)
基因简称更名时间(date_symbol_changed)
基因名称更名时间(date_name_changed)
更新时间(date_modified)
ucsc码
ena
ccds数据码
uniprot数据码
pubmed代码
mgd码
rgd码
生命科学数据库(lsdb)
更新时间(date modified)
cosmic
mirbase
基因曾用简称(prev symbol)
基因曾用名称(prev name)
homeodb
cosmic
snornabase
bioparadigms slc
orphanet
假基因信息(pseudogeneorg)
horde id
merops
imgt
iuphar
kznf基因类别
mamit-trnadb
cd
LncRNA数据库
酶代码
中间纤维数据库
收起
This protein belongs to the basic helix-loop-helix family of transcription factors. It is a transcriptional repressor of genes that require a bHLH protein for their transcription. The protein has a particular type of basic domain that contains a helix interrupting protein that binds to the N-box rather than the canonical E-box. [provided by RefSeq, Jul 2008]
[中文简述(自动翻译):] 这种蛋白质属于碱性螺旋 - 环 - 螺旋转录因子家族。它是那些需要对他们的转录的bHLH蛋白质的基因的转录阻遏。该蛋白质具有特定的类型，它包含结合的N箱，而不是典型的E盒的螺旋线中断蛋白质基本域的。 [由RefSeq的，2008年7月提供]
HES1基因的碱基突变：
显示全部snp
rs2236747
rs2368048
rs7629144
rs11541817
rs16825120
rs17853878
rs35578304
rs55782996
rs73889562
rs73889564
rs76154729
rs76688672
rs76884559
rs77484716
rs77930285
rs79406699
rs112278954
rs112770159
rs113839026
rs114479819
rs115098832
rs138053059
rs138179995
rs139969827
rs140091125
rs140499194
rs140832484
rs141151553
rs141702996
rs141717320
rs142811204
rs143349653
rs143989305
rs144093966
rs144550814
rs144918671
rs146475355
rs147306621
rs148185681
rs148500265
rs149421852
rs180757055
rs181836946
rs183463316
rs183540789
rs184573427
rs185082620
rs186088852
rs186229970
rs187934082
rs189121516
rs189428526
rs191244380
rs192979269
rs199804897
rs199954308
rs200025294
rs200519788
rs200652569
rs200676803
rs201323213
rs201485416
rs202025564
rs367544660
rs368018053
rs368074565
rs368670456
rs368744295
rs369479761
rs369747562
rs370532968
rs370545766
rs370560541
rs370952700
rs370999458
rs371168546
rs371931539
rs372366870
rs373745774
rs373750310
rs373997718
rs374200582
rs374513189
rs374962781
rs375649870
rs375956601
rs376058357
rs376638002
rs377586700
rs527390105
rs531364020
rs533133475
rs534697548
rs534989493
rs535241570
rs535403208
rs535463419
rs536653531
rs537582585
rs537722442
rs538095047
rs539014312
rs539970957
rs540227829
rs540940171
rs541228886
rs541790650
rs541856003
rs543035753
rs543079208
rs543141854
rs543207541
rs544094665
rs545286155
rs545794201
rs546816281
rs547170834
rs549531201
rs549620199
rs549696067
rs550760489
rs550878016
rs551535737
rs552075162
rs552276312
rs555065780
rs556055338
rs557234960
rs557311820
rs558046804
rs559325563
rs559600981
rs560132506
rs561173710
rs561652499
rs562387858
rs563595555
rs563654088
rs564108369
rs565442140
rs566413359
rs567823362
rs568027381
rs568088018
rs569283175
rs571779186
rs571901099
rs573709642
rs573978904
rs574438669
rs575666622
rs575732734
rs576611813
rs576680520
rs577865305
rs745482084
rs745488699
rs745559707
rs745968591
rs746003174
rs746035881
rs746105170
rs746295207
rs746597896
rs746603112
rs746690094
rs746857219
rs747483846
rs747710157
rs747712250
rs747802149
rs748351351
rs748528868
rs748701367
rs749170067
rs749484323
rs749724903
rs749759771
rs749803709
rs749842469
rs749947606
rs749953164
rs749965976
rs750095094
rs750258090
rs750607048
rs750862335
rs750899762
rs750971331
rs751170908
rs751544858
rs751681638
rs751813734
rs752003910
rs752193093
rs752481273
rs752530595
rs752802101
rs752814842
rs752866226
rs753104474
rs753966015
rs754359358
rs754662672
rs754761992
rs754952671
rs755168669
rs755302910
rs755506528
rs755738390
rs755791747
rs755810702
rs756629163
rs756671677
rs756738193
rs756981139
rs757484984
rs757591834
rs757649899
rs757828005
rs757882940
rs757883081
rs758054971
rs758181488
rs758451875
rs758663080
rs758733317
rs758976084
rs759032037
rs759491695
rs759832570
rs759980470
rs760003455
rs760170936
rs760405984
rs760512057
rs760641858
rs760701768
rs760767161
rs760964574
rs761011090
rs761404813
rs761506546
rs761532401
rs761876517
rs762149315
rs762400765
rs762484355
rs762801578
rs762888015
rs763157660
rs763345651
rs763666288
rs763805635
rs763850405
rs763999161
rs764280631
rs764460072
rs764774667
rs764875645
rs765027516
rs765029528
rs765207361
rs765370189
rs765501070
rs765840154
rs765947521
rs766000709
rs766153243
rs766197711
rs766656260
rs766966099
rs767463400
rs767688346
rs767825545
rs767833391
rs767844444
rs767878985
rs768003263
rs768161203
rs768393487
rs768638212
rs769025125
rs769092836
rs769232702
rs769537357
rs770004050
rs770193881
rs770700307
rs770915957
rs770938865
rs771094115
rs771360458
rs771445679
rs771772450
rs771809938
rs771902329
rs772094953
rs772146327
rs772289026
rs772865114
rs772939826
rs773063884
rs773467524
rs774021862
rs774041130
rs774229432
rs774862591
rs774891976
rs774940691
rs775054820
rs775109797
rs775223641
rs775245326
rs775456877
rs775721411
rs775921226
rs776375516
rs776397886
rs776407796
rs776494944
rs776903500
rs776936357
rs777042921
rs777698207
rs778207554
rs778255823
rs778267434
rs778309752
rs778486827
rs778639736
rs778900204
rs778939220
rs779025770
rs779369881
rs779402475
rs779634117
rs779690745
rs780087324
rs780122282
rs780206874
rs780251181
rs780545366
rs780654821
rs780710032
rs780887760
rs781005681
rs781438851
rs781482798
正向引物序列
正向引物Tm值
反向引物序列
反向引物Tm值
rank
CACAGAAAGTCATCAAAGCC
57
CATCTTTCTTCAGAGCATCCA
58
TGCCAGCTGATATAATGGAG
57
CTTTGATGACTTTCTGTGCTC
58
ACAGAAAGTCATCAAAGCCT
58
ACATCTTTCTTCAGAGCATCC
58
TGCCAGCTGATATAATGGAG
57
GCTTTGATGACTTTCTGTGC
58
ACAGAAAGTCATCAAAGCCT
58
CATCTTTCTTCAGAGCATCCA
58
TGCCAGCTGATATAATGGAG
57
GGCTTTGATGACTTTCTGTG
57
基因本体信息
HES1基因（以及对应的蛋白质）的细胞分布位置：
- 溶酶体
- 内涵体
- 细胞核
- 细胞质
- 液泡
- 细胞膜
- 细胞外基质
- 内质网
- 线粒体
- 高尔基体
- 细胞骨架
HES1基因的本体（GO）信息：
GO库代码
对应的蛋白质
来源代码
GO:0000122
Q14469(UniProtKB)
IDA
GO:0000122
Q14469(UniProtKB)
IDA
GO:0001078
Q14469(UniProtKB)
ISS
GO:0001889
Q14469(UniProtKB)
IEA
GO:0003143
Q14469(UniProtKB)
ISS
GO:0003151
Q14469(UniProtKB)
ISS
GO:0003266
Q14469(UniProtKB)
IEA
GO:0003281
Q14469(UniProtKB)
ISS
GO:0003677
Q14469(UniProtKB)
TAS
GO:0003700
Q14469(UniProtKB)
IDA
GO:0005515
Q14469(UniProtKB)
IPI
GO:0005634
Q14469(UniProtKB)
ISS
GO:0005654
Q14469(UniProtKB)
IDA
GO:0005654
Q14469(UniProtKB)
TAS
GO:0005737
Q14469(UniProtKB)
IEA
GO:0006351
Q14469(UniProtKB)
IEA
GO:0006461
Q14469(UniProtKB)
ISS
GO:0007155
Q14469(UniProtKB)
IEA
GO:0007219
Q14469(UniProtKB)
IDA
GO:0007219
Q14469(UniProtKB)
IMP
GO:0007224
Q14469(UniProtKB)
IEA
GO:0007262
Q14469(UniProtKB)
ISS
GO:0007399
Q14469(UniProtKB)
TAS
GO:0008134
Q14469(UniProtKB)
NAS
GO:0008284
Q14469(UniProtKB)
ISS
GO:0016477
Q14469(UniProtKB)
IEA
GO:0021537
Q14469(UniProtKB)
IEA
GO:0021555
Q14469(UniProtKB)
IEA
GO:0021557
Q14469(UniProtKB)
IEA
GO:0021558
Q14469(UniProtKB)
IEA
GO:0021575
Q14469(UniProtKB)
IEA
GO:0021861
Q14469(UniProtKB)
ISS
GO:0021984
Q14469(UniProtKB)
IEA
GO:0030324
Q14469(UniProtKB)
IEA
GO:0030513
Q14469(UniProtKB)
IEA
GO:0030901
Q14469(UniProtKB)
IEA
GO:0031016
Q14469(UniProtKB)
IEA
GO:0035019
Q14469(UniProtKB)
IEA
GO:0035910
Q14469(UniProtKB)
ISS
GO:0042102
Q14469(UniProtKB)
IEA
GO:0042517
Q14469(UniProtKB)
ISS
GO:0042668
Q14469(UniProtKB)
IEA
GO:0042803
Q14469(UniProtKB)
ISS
GO:0042826
Q14469(UniProtKB)
IPI
GO:0043388
Q14469(UniProtKB)
ISS
GO:0043565
Q14469(UniProtKB)
ISS
GO:0045598
Q14469(UniProtKB)
IEA
GO:0045608
Q14469(UniProtKB)
IEA
GO:0045747
Q14469(UniProtKB)
IEA
GO:0045892
Q14469(UniProtKB)
IDA
GO:0045944
Q14469(UniProtKB)
ISS
GO:0045977
Q14469(UniProtKB)
ISS
GO:0046331
Q14469(UniProtKB)
IEA
GO:0046427
Q14469(UniProtKB)
ISS
GO:0048469
Q14469(UniProtKB)
IEA
GO:0048538
Q14469(UniProtKB)
ISS
GO:0048667
Q14469(UniProtKB)
IEA
GO:0048711
Q14469(UniProtKB)
ISS
GO:0048715
Q14469(UniProtKB)
ISS
GO:0048844
Q14469(UniProtKB)
ISS
GO:0050678
Q14469(UniProtKB)
IEA
GO:0051087
Q14469(UniProtKB)
IEA
GO:0060122
Q14469(UniProtKB)
IEA
GO:0060164
Q14469(UniProtKB)
IEA
GO:0060253
Q14469(UniProtKB)
ISS
GO:0060412
Q14469(UniProtKB)
ISS
GO:0060675
Q14469(UniProtKB)
IEA
GO:0060716
Q14469(UniProtKB)
IEA
GO:0061009
Q14469(UniProtKB)
IEA
GO:0061106
Q14469(UniProtKB)
IEA
GO:0061309
Q14469(UniProtKB)
IEA
GO:0061626
Q14469(UniProtKB)
ISS
GO:0071820
Q14469(UniProtKB)
ISS
GO:0072012
Q14469(UniProtKB)
IEA
GO:0072049
Q14469(UniProtKB)
IEA
GO:0072050
Q14469(UniProtKB)
IEA
GO:0072141
Q14469(UniProtKB)
IEA
GO:0072282
Q14469(UniProtKB)
IEA
GO:0090102
Q14469(UniProtKB)
IEA
GO:0090162
Q14469(UniProtKB)
IEA
GO:0097084
Q14469(UniProtKB)
ISS
GO:0097150
Q14469(UniProtKB)
IEP
GO:1903955
Q14469(UniProtKB)
IMP
GO:2000227
Q14469(UniProtKB)
IEA
GO:2000737
Q14469(UniProtKB)
IMP
GO:2000974
Q14469(UniProtKB)
IMP
GO:2000978
Q14469(UniProtKB)
ISS
| 疾病名称 | 关系值 | NofPmids | NofSnps | 来源 |
| Mammary Neoplasms | 0.12272435 | 3 | 0 | CTD_human_LHGDN |
| Meningioma | 0.120542884 | 3 | 0 | BeFree_CTD_human |
| Lung Neoplasms | 0.120271442 | 2 | 0 | BeFree_CTD_human |
| Non-Small Cell Lung Carcinoma | 0.12 | 1 | 0 | CTD_human |
| Uterine Cervical Neoplasm | 0.12 | 1 | 0 | CTD_human |
| Colonic Neoplasms | 0.12 | 1 | 0 | CTD_human |
| Glioblastoma | 0.12 | 1 | 0 | CTD_human |
| oligodendroglioma | 0.12 | 1 | 0 | CTD_human |
| Neuroectodermal Tumor, Primitive | 0.12 | 1 | 0 | CTD_human |
| Lymphangioleiomyomatosis | 0.12 | 1 | 0 | CTD_human |
| Carcinoma, Pancreatic Ductal | 0.12 | 1 | 0 | CTD_human |
| Myeloid Leukemia, Chronic | 0.080542884 | 3 | 0 | BeFree_RGD |
| Epilepsy | 0.08 | 1 | 0 | RGD |
| Acute kidney injury | 0.08 | 2 | 0 | RGD |
| Attention deficit hyperactivity disorder | 0.004734064 | 2 | 0 | GAD |
| Fanconi Anemia | 0.003538676 | 3 | 0 | BeFree_LHGDN |
| Precursor T-Cell Lymphoblastic Leukemia-Lymphoma | 0.001628651 | 6 | 0 | BeFree |
| Malignant neoplasm of lung | 0.001357209 | 5 | 0 | BeFree |
| Carcinoma of lung | 0.001357209 | 5 | 0 | BeFree |
| leukemia | 0.001085767 | 4 | 0 | BeFree |
| Leukemia, Myelocytic, Acute | 0.001085767 | 4 | 0 | BeFree |
| Malignant neoplasm of stomach | 0.001085767 | 4 | 0 | BeFree |
| Medulloblastoma | 0.001085767 | 4 | 0 | BeFree |
| Liver carcinoma | 0.001085767 | 4 | 0 | BeFree |
| Blast Phase | 0.000814326 | 3 | 0 | BeFree |
| Malignant neoplasm of breast | 0.000814326 | 3 | 0 | BeFree |
| Glioma | 0.000814326 | 3 | 0 | BeFree |
| Neuroblastoma | 0.000814326 | 3 | 0 | BeFree |
| Rhabdomyosarcoma | 0.000814326 | 3 | 0 | BeFree |
| Small cell carcinoma of lung | 0.000814326 | 3 | 0 | BeFree |
| Pancreatic carcinoma | 0.000814326 | 3 | 0 | BeFree |
| Malignant neoplasm of pancreas | 0.000814326 | 3 | 0 | BeFree |
| Carcinogenesis | 0.000814326 | 3 | 0 | BeFree |
| Breast Carcinoma | 0.000814326 | 3 | 0 | BeFree |
| Stomach Carcinoma | 0.000814326 | 3 | 0 | BeFree |
| Central neuroblastoma | 0.000814326 | 3 | 0 | BeFree |
| FANCONI ANEMIA, COMPLEMENTATION GROUP A (disorder) | 0.000814326 | 3 | 0 | BeFree |
| Adenocarcinoma | 0.000542884 | 2 | 0 | BeFree |
| Malignant tumor of colon | 0.000542884 | 2 | 0 | BeFree |
| Colorectal Carcinoma | 0.000542884 | 2 | 0 | BeFree |
| Leukemia, T-Cell | 0.000542884 | 2 | 0 | BeFree |
| Obesity | 0.000542884 | 2 | 0 | BeFree |
| Pancreatic Neoplasm | 0.000542884 | 2 | 0 | BeFree |
| Psoriasis | 0.000542884 | 2 | 0 | BeFree |
| Cholangiocarcinoma | 0.000542884 | 2 | 0 | BeFree |
| Malignant neoplasm of prostate | 0.000542884 | 2 | 0 | BeFree |
| Prostate carcinoma | 0.000542884 | 2 | 0 | BeFree |
| Colon Carcinoma | 0.000542884 | 2 | 0 | BeFree |
| Colorectal Cancer | 0.000542884 | 2 | 0 | BeFree |
| Non-Neoplastic Disorder | 0.000542884 | 2 | 0 | BeFree |
| Adenoma | 0.000271442 | 1 | 0 | BeFree |
| Amyotrophic Lateral Sclerosis | 0.000271442 | 1 | 0 | BeFree |
| Anaplasia | 0.000271442 | 1 | 0 | BeFree |
| Aortic Aneurysm | 0.000271442 | 1 | 0 | BeFree |
| Astrocytoma | 0.000271442 | 1 | 0 | BeFree |
| Malignant neoplasm of urinary bladder | 0.000271442 | 1 | 0 | BeFree |
| Cachexia | 0.000271442 | 1 | 0 | BeFree |
| Cholangitis, Sclerosing | 0.000271442 | 1 | 0 | BeFree |
| Ulcerative Colitis | 0.000271442 | 1 | 0 | BeFree |
| Diabetes Mellitus, Insulin-Dependent | 0.000271442 | 1 | 0 | BeFree |
| Diabetic Nephropathy | 0.000271442 | 1 | 0 | BeFree |
| Ependymoma | 0.000271442 | 1 | 0 | BeFree |
| Epilepsy, Temporal Lobe | 0.000271442 | 1 | 0 | BeFree |
| Intestinal Neoplasms | 0.000271442 | 1 | 0 | BeFree |
| Acute lymphocytic leukemia | 0.000271442 | 1 | 0 | BeFree |
| Liver neoplasms | 0.000271442 | 1 | 0 | BeFree |
| melanoma | 0.000271442 | 1 | 0 | BeFree |
| Muscular Atrophy | 0.000271442 | 1 | 0 | BeFree |
| Osteosarcoma | 0.000271442 | 1 | 0 | BeFree |
| Ovarian Carcinoma | 0.000271442 | 1 | 0 | BeFree |
| Prostatic Neoplasms | 0.000271442 | 1 | 0 | BeFree |
| B-Cell Lymphomas | 0.000271442 | 1 | 0 | BeFree |
| Secondary malignant neoplasm of lung | 0.000271442 | 1 | 0 | BeFree |
| Aortic Aneurysm, Thoracic | 0.000271442 | 1 | 0 | BeFree |
| Adenosquamous carcinoma | 0.000271442 | 1 | 0 | BeFree |
| Hepatoblastoma | 0.000271442 | 1 | 0 | BeFree |
| Mucoepidermoid Carcinoma | 0.000271442 | 1 | 0 | BeFree |
| Ectopic pancreas | 0.000271442 | 1 | 0 | BeFree |
| Gastrointestinal Stromal Tumors | 0.000271442 | 1 | 0 | BeFree |
| Anaplastic thyroid carcinoma | 0.000271442 | 1 | 0 | BeFree |
| Squamous cell carcinoma of esophagus | 0.000271442 | 1 | 0 | BeFree |
| Hyperplastic Polyp | 0.000271442 | 1 | 0 | BeFree |
| Pilocytic Astrocytoma | 0.000271442 | 1 | 0 | BeFree |
| Optic Atrophy, Autosomal Dominant | 0.000271442 | 1 | 0 | BeFree |
| Endometrial Carcinoma | 0.000271442 | 1 | 0 | BeFree |
| Recurrent tumor | 0.000271442 | 1 | 0 | BeFree |
| Primary sclerosing cholangitis | 0.000271442 | 1 | 0 | BeFree |
| Osteosarcoma of bone | 0.000271442 | 1 | 0 | BeFree |
| Biliary Intraepithelial Neoplasia | 0.000271442 | 1 | 0 | BeFree |
| Leukemogenesis | 0.000271442 | 1 | 0 | BeFree |
| Carcinoma of bladder | 0.000271442 | 1 | 0 | BeFree |
| Biliary Tract Cancer | 0.000271442 | 1 | 0 | BeFree |
| Malignant neoplasm of ovary | 0.000271442 | 1 | 0 | BeFree |
| Sarcoma | 0.000271442 | 1 | 0 | BeFree |
| Large cell neuroendocrine carcinoma | 0.000271442 | 1 | 0 | BeFree |
| Differentiating Neuroblastoma | 0.000271442 | 1 | 0 | BeFree |
| Hepatocarcinogenesis | 0.000271442 | 1 | 0 | BeFree |
| Meningioma, benign, no ICD-O subtype | 0.000271442 | 1 | 0 | BeFree |
| Aortic aneurysm and dissection | 0.000271442 | 1 | 0 | BeFree |
| Intracranial glioma | 0.000271442 | 1 | 0 | BeFree |
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