HBD(hemoglobin, delta) 转至新版数据库

基因基本信息

基因基本信息

基因简称(symbol)
    [HGNC]     [GeneCards]     [NCBI]
基因种类(locus group)
同源简称(alias symbol)
基因家族代码(gene_family_id)
    [HGNC]     [GenScript]
omim代码
entrez码
    [Vega]
vega基因码
ensembl基因码
    [Ensembl]
基因家族(gene family)
refseq数据库代号

更多...

基因种类(locus_type)
基因名称状态(status)
location_sortable
同源基因名称(alias name)
基因名称批准使用时间(date_approved_reserved)
基因简称更名时间(date_symbol_changed)
基因名称更名时间(date_name_changed)
更新时间(date_modified)
ucsc码
ena
ccds数据码
uniprot数据码
pubmed代码
mgd码
rgd码
生命科学数据库(lsdb)
更新时间(date modified)
cosmic
mirbase
基因曾用简称(prev symbol)
基因曾用名称(prev name)
homeodb
cosmic
snornabase
bioparadigms slc
orphanet
假基因信息(pseudogeneorg)
horde id
merops
imgt
iuphar
kznf基因类别
mamit-trnadb
cd
LncRNA数据库
酶代码
中间纤维数据库

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基因染色体位置

基因染色体位置

11p15.5
基因染色体位置图

基因简述

基因简述

The delta (HBD) and beta (HBB) genes are normally expressed in the adult: two alpha chains plus two beta chains constitute HbA, which in normal adult life comprises about 97% of the total hemoglobin. Two alpha chains plus two delta chains constitute HbA-2, which with HbF comprises the remaining 3% of adult hemoglobin. Five beta-like globin genes are found within a 45 kb cluster on chromosome 11 in the following order: 5'-epsilon--Ggamma--Agamma--delta--beta-3'. Mutations in the delta-globin gene are associated with beta-thalassemia. [provided by RefSeq, Jul 2008]

[中文简述(自动翻译):]  增量（HBD）和β（HBB）基因在成人通常表示为：两个α链和两个β链构成的HBA，在正常成年人的生活包括血红蛋白总量的97％左右。两个α链和两个增量链构成的HbA-2，其与HbF的包括成人血红蛋白的其余3％。五β样珠蛋白基因在按以下顺序一个45 kb的簇内发现11号染色体上：5‘-ε - Ggamma - Agamma - 三角洲 - β-3‘。在增量珠蛋白基因突变与β-地中海贫血相关联。 [由RefSeq的，2008年7月提供]

OMIM数据库中对HBD基因的介绍     Wikipedia数据库中对HBD基因的介绍

基因序列

基因序列

HBD基因的碱基序列：[NCBI]

基因突变

基因突变

HBD基因的碱基突变：           显示全部snp
rs3752382       rs3759074       rs3759075       rs3759076       rs3813726       rs3813727       rs7115375       rs7936253       rs7948416       rs7948668       rs9665964       rs10637609       rs11822199       rs16911951       rs16911998       rs28933076       rs28933077       rs33956485       rs33971270       rs34012192       rs34090605       rs34093840       rs34149886       rs34166473       rs34235091       rs34289459       rs34313675       rs34373781       rs34383555       rs34389944       rs34390965       rs34420481       rs34430836       rs34460332       rs34489183       rs34536353       rs34796568      
rs34933313       rs34975911       rs34977235       rs34991152       rs35152987       rs35166721       rs35291639       rs35329985       rs35395083       rs35406175       rs35408031       rs35433207       rs35518301       rs35540211       rs35633566       rs35654785       rs35666685       rs35769679       rs35781729       rs35790721       rs35848600       rs35849348       rs35887507       rs35913713       rs36023765       rs36049174       rs36078803       rs36084266       rs61746501       rs63750345       rs63750423       rs73400692       rs73400693       rs73400696       rs74049332       rs76445361       rs77044643       rs78192467       rs79395249       rs79582489       rs79659287       rs80018520       rs80138317       rs111614150       rs111671911       rs111771479       rs111838663       rs112138553       rs112372029       rs112419303       rs112501038       rs112630078       rs112645511       rs112768191       rs112804222       rs112914556       rs113029322       rs113088822       rs113277983       rs113546557       rs113698124       rs113727122       rs113846417       rs114744009       rs138681161       rs140031290       rs141089429       rs142196122       rs142519583       rs143576561       rs144059558       rs144322869       rs144614865       rs146567736       rs148005706       rs148878316       rs149402829       rs149742302       rs150695348       rs151221946       rs181334077       rs183094345       rs183100885       rs184925254       rs186272175       rs186432678       rs186609557       rs187907757       rs188907622       rs189737412       rs189985831       rs190495739       rs192839783       rs199907531       rs200027473       rs200109778       rs200264296       rs200447178       rs200910779       rs201314214       rs202223735       rs281864492       rs281864507       rs281864510       rs281864512       rs367578689       rs367583721       rs368389253       rs368431101       rs369302303       rs369305779       rs369514517       rs369519514       rs369527852       rs369735914       rs369906206       rs370683880       rs370975841       rs371945255       rs372352398       rs372403672       rs373887637       rs374131564       rs374210782       rs375783446       rs376016891       rs527736202       rs527825131       rs528751190       rs528980418       rs529013009       rs529558623       rs531552954       rs531748842       rs531833608       rs533096079       rs533171577       rs533796952       rs535383249       rs535900324       rs535928001       rs536267270       rs537384442       rs537709078       rs538033464       rs539736726       rs540457381       rs541994611       rs542724266       rs543938702       rs544893122       rs545297710       rs545807069       rs547414906       rs547725279       rs547910695       rs548900331       rs549464344       rs549964658       rs550414185       rs551389415       rs553440422       rs553934080       rs554665159       rs554710193       rs555570708       rs555837097       rs556379797       rs557074441       rs557080433       rs558946023       rs560160001       rs561677601       rs562503033       rs562543884       rs563695406       rs564626562       rs564719605       rs565124787       rs566610057       rs567792872       rs568368437       rs568957767       rs570832829       rs571237718       rs572163623       rs572417936       rs572705102       rs574124272       rs575365253       rs577730357       rs577814924       rs577823914       rs577951575       rs606231215       rs745410465       rs745518996       rs745903482       rs745991754       rs746381682       rs746437527       rs747164859       rs747542274       rs747597296       rs747684647       rs748762381       rs748854002       rs749165451       rs749319105       rs749699838       rs750285044       rs750372909       rs750537153       rs750803605       rs751113654       rs751533248       rs751899784       rs752267726       rs753267571       rs753525863       rs753866251       rs753983305       rs754032434       rs754605506       rs755092732       rs755109846       rs755421119       rs755491259       rs755850441       rs756391115       rs756655365       rs757106601       rs757119395       rs757450561       rs757622703       rs758390249       rs758478152       rs758609186       rs758794883       rs758984002       rs759183238       rs759483345       rs759832815       rs760253611       rs760410061       rs760656420       rs761120445       rs761141873       rs761431322       rs761527836       rs761912845       rs762198004       rs762782488       rs762875104       rs763208471       rs763612563       rs764058749       rs764123860       rs764233236       rs764557786       rs765120810       rs765290999       rs765291272       rs766444273       rs766562887       rs766579794       rs766699832       rs767977793       rs768225600       rs768455511       rs768541840       rs768890649       rs769446735       rs769765023       rs770433973       rs770533831       rs770655644       rs770750995       rs770965596       rs771686740       rs771732360       rs772372210       rs772497026       rs773007023       rs773050659       rs773095083       rs773323524       rs774077053       rs774174189       rs774952470       rs774957917       rs775204519       rs775324787       rs775974177       rs776071703       rs776350698       rs776469164       rs777424481       rs777487918       rs777991732       rs778078035       rs778560190       rs778647928       rs778826800       rs778926249       rs779015865       rs779230012       rs779604715       rs780252589       rs780340388       rs780371498       rs780459430       rs780464320       rs781735687       rs781769236       rs866184656      

基因表达

基因表达

HBD基因在不同组织中的表达：    [UniProt]

基因在不同组织中的表达图

基因引物

基因引物

正向引物序列
正向引物Tm值
反向引物序列
反向引物Tm值
rank
GAAGACTGCTGTCAATGCC
59
AGACCACCAGTAATCTGCC
59
GAAGACTGCTGTCAATGCC
59
AGACCACCAGTAATCTGCC
59
AAAGTGAACGTGGATGCAG
59
AATTCCTTGCCAAAGTTGC
57
GAAGACTGCTGTCAATGCC
59
TAGACCACCAGTAATCTGCC
59
CTGAGAACTTCAGGGTGTG
58
TTAATGCCTTGTACGGTTCC
58
AAAGTGAACGTGGATGCAG
59
ATTCCTTGCCAAAGTTGCG
60
AGAACTTCAGGCTCTTGGG
59
ACCACCTTCTGATAGGCAG
59
AGAAGACTGCTGTCAATGC
58
AGACCACCAGTAATCTGCC
59
CTGAGAACTTCAGGGTGTG
58
TAATGCCTTGTACGGTTCC
58
AGAACTTCAGGCTCTTGGG
59
CACCACCTTCTGATAGGCA
59

转录因子

转录因子

      尚未收录相关数据

基因本体信息

HBD基因（以及对应的蛋白质）的细胞分布位置：

[UniProt]     [GenomeNet]

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • 溶酶体
  • 内涵体
  • 细胞核
  • 细胞质
  • 液泡
  • 细胞膜
  • 细胞外基质
  • 内质网
  • 线粒体
  • 高尔基体
  • 细胞骨架

HBD基因的本体（GO）信息：

GO库代码
对应的蛋白质
来源代码
GO:0016021
C9JRG0(UniProtKB)
IEA
GO:0019825
C9JRG0(UniProtKB)
IEA
GO:0020037
C9JRG0(UniProtKB)
IEA
GO:0005344
E9PEW8(UniProtKB)
IEA
GO:0005506
E9PEW8(UniProtKB)
IEA
GO:0005833
E9PEW8(UniProtKB)
IEA
GO:0015671
E9PEW8(UniProtKB)
IEA
GO:0019825
E9PEW8(UniProtKB)
IEA
GO:0020037
E9PEW8(UniProtKB)
IEA
GO:0005344
E9PFT6(UniProtKB)
IEA
GO:0005506
E9PFT6(UniProtKB)
IEA
GO:0005833
E9PFT6(UniProtKB)
IEA
GO:0015671
E9PFT6(UniProtKB)
IEA
GO:0019825
E9PFT6(UniProtKB)
IEA
GO:0020037
E9PFT6(UniProtKB)
IEA
GO:0005344
P02042(UniProtKB)
IEA
GO:0005506
P02042(UniProtKB)
IEA
GO:0005515
P02042(UniProtKB)
IPI
GO:0005515
P02042(UniProtKB)
IPI
GO:0005829
P02042(UniProtKB)
TAS
GO:0005833
P02042(UniProtKB)
IEA
GO:0007596
P02042(UniProtKB)
TAS
GO:0015671
P02042(UniProtKB)
IEA
GO:0019825
P02042(UniProtKB)
IEA
GO:0020037
P02042(UniProtKB)
IEA
GO:0072562
P02042(UniProtKB)
IDA

基因相互作用关系

基因相互作用关系

基因与其他基因之间的相互作用关系图
序号 作用方式 资源库来源/分值 基因名称 基因名称

基因相关microRNA

基因相关microRNA

可能调控HBD基因的相关microRNA：     

基因通路图

基因通路图

基因的通路属性图
通路基因列表

基因相关疾病

基因相关疾病

疾病名称 关系值 NofPmids NofSnps 来源
疾病名称 关系值 NofPmids NofSnps 来源
delta-Thalassemia 0.122985861 11 7 BeFree_CLINVAR
Keloid 0.12 1 0 CTD_human
Chloracne 0.12 1 0 CTD_human
beta Thalassemia 0.00434307 16 0 BeFree
alpha-Thalassemia 0.00272435 1 0 LHGDN
Thalassemia 0.002714419 10 0 BeFree
Delta-Beta Thalassemia 0.001628651 6 0 BeFree
Hereditary persistence of fetal hemoglobin thalassemia 0.001357209 5 0 BeFree
beta^0^ Thalassemia 0.001085767 4 0 BeFree
Hemoglobinopathies 0.000814326 3 0 BeFree
delta-Thalassemia 0.000814326 3 0 BeFree
Beta thalassemia trait 0.000814326 3 0 BeFree
Anemia, Sickle Cell 0.000542884 2 0 BeFree
Hemoglobin F Disease 0.000542884 2 0 BeFree
delta^0^ Thalassemia 0.000542884 2 0 BeFree
Rhinitis 0.000271442 1 0 BeFree
Rhinitis 0.000271442 1 0 BeFree
Iron deficiency anemia 0.000271442 1 0 BeFree
Thalassemia Intermedia 0.000271442 1 0 BeFree
^A^gamma delta beta^0^ thalassemia 0.000271442 1 0 BeFree
alpha^0^ Thalassemia 0.000271442 1 0 BeFree
Beta thalassemia intermedia 0.000271442 1 0 BeFree
Experimental Organism Basal Cell Carcinoma 0.000271442 1 0 BeFree
Experimental Organism Basal Cell Carcinoma 0.000271442 1 0 BeFree

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