H3F3A(H3 histone, family 3A) 转至新版数据库

基因基本信息

基因基本信息

基因简称(symbol)
    [HGNC]     [GeneCards]     [NCBI]
基因种类(locus group)
同源简称(alias symbol)
基因家族代码(gene_family_id)
    [HGNC]     [GenScript]
omim代码
entrez码
    [Vega]
vega基因码
ensembl基因码
    [Ensembl]
基因家族(gene family)
refseq数据库代号

更多...

基因种类(locus_type)
基因名称状态(status)
location_sortable
同源基因名称(alias name)
基因名称批准使用时间(date_approved_reserved)
基因简称更名时间(date_symbol_changed)
基因名称更名时间(date_name_changed)
更新时间(date_modified)
ucsc码
ena
ccds数据码
uniprot数据码
pubmed代码
mgd码
rgd码
生命科学数据库(lsdb)
更新时间(date modified)
cosmic
mirbase
基因曾用简称(prev symbol)
基因曾用名称(prev name)
homeodb
cosmic
snornabase
bioparadigms slc
orphanet
假基因信息(pseudogeneorg)
horde id
merops
imgt
iuphar
kznf基因类别
mamit-trnadb
cd
LncRNA数据库
酶代码
中间纤维数据库

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基因染色体位置

基因染色体位置

1q42.12
基因染色体位置图

基因简述

基因简述

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene contains introns and its mRNA is polyadenylated, unlike most histone genes. The protein encoded is a replication-independent member of the histone H3 family. [provided by RefSeq, Jul 2008]

[中文简述(自动翻译):]  组蛋白是负责在真核生物染色体纤维的核小体结构基本核蛋白质。每四个核心组蛋白中的两个分子（H2A，H2B，H3和H4）形成八聚体，其周围约146的DNA的碱基被包裹在重复单元，称为核小体。接头组蛋白，H1与染色质成高阶结构的压实核小体和功能之间的接头DNA相互作用。该基因内含子中含有及其mRNA的聚腺苷酸化，不像大多数组蛋白的基因。编码的蛋白是组蛋白H3家族的一个复制的独立成员。 [由RefSeq的，2008年7月提供]

OMIM数据库中对H3F3A基因的介绍     Wikipedia数据库中对H3F3A基因的介绍

基因序列

基因序列

H3F3A基因的碱基序列：[NCBI]

基因突变

基因突变

H3F3A基因的碱基突变：           显示全部snp
rs1511056       rs1533114       rs1849032       rs2036870       rs3768543       rs3795441       rs3832021       rs4012724       rs4653440       rs6664668       rs6672433       rs6678547       rs6700189       rs6702795       rs11321424       rs12086044       rs12096468       rs34485485       rs34523945       rs41268721       rs41268727       rs56268212       rs57574072       rs60311516       rs61835218       rs68109929       rs71574556       rs71574557       rs73083530       rs74537211       rs75351784       rs75944134       rs76140701       rs76378622       rs77453046       rs77853027       rs78034836      
rs78817141       rs79025726       rs79716952       rs79811662       rs80080024       rs111242638       rs111674076       rs112211611       rs112466115       rs112538282       rs113109769       rs113600305       rs113607730       rs114372705       rs114553724       rs114807066       rs115501706       rs115728567       rs115920645       rs115928147       rs116217448       rs116271913       rs116389985       rs116528960       rs116537562       rs116608740       rs116702928       rs117658647       rs138543548       rs138566582       rs138596681       rs138859445       rs139717036       rs139897261       rs139935199       rs140145865       rs140546890       rs140655950       rs141278739       rs141507178       rs141810346       rs142395336       rs142474987       rs142791657       rs142810766       rs143198531       rs143423551       rs143861201       rs143986147       rs144209387       rs144361830       rs144702377       rs144758249       rs146871780       rs147131207       rs147478485       rs147487676       rs148060720       rs148714515       rs149850704       rs149984625       rs150322178       rs150585393       rs150803163       rs180806751       rs181076732       rs181130910       rs181653521       rs182244514       rs182471323       rs182528753       rs183001360       rs183082978       rs183985096       rs184029346       rs184595486       rs184832637       rs184902009       rs185624405       rs185655925       rs185979947       rs186193442       rs186461649       rs187153427       rs187183228       rs187242044       rs187751959       rs187897594       rs187953480       rs187973612       rs188705876       rs189265172       rs189291924       rs190068374       rs190452787       rs190693611       rs190759936       rs190826552       rs191548658       rs192058159       rs192120315       rs192330336       rs192446563       rs192860670       rs193279136       rs199699563       rs200633260       rs201081886       rs369284826       rs369435015       rs369728961       rs370230636       rs371058324       rs371554002       rs371556784       rs372728644       rs372851355       rs373121860       rs373746348       rs373995132       rs374324778       rs375206998       rs376494719       rs376524805       rs398050139       rs398050140       rs527449567       rs527653714       rs527996628       rs528154532       rs528570455       rs528863488       rs529117981       rs529212540       rs529307084       rs529367270       rs529382916       rs529396951       rs529736003       rs529748141       rs531037618       rs531329531       rs532021950       rs532066771       rs532531600       rs532927417       rs533054125       rs533140932       rs533441464       rs533668320       rs533895467       rs534427048       rs534490757       rs534725802       rs534729673       rs534909280       rs534987310       rs535736578       rs536171329       rs536175799       rs536712065       rs536947753       rs537149853       rs537478161       rs537970405       rs538284272       rs538453271       rs538804139       rs539089071       rs539733599       rs540128420       rs540215894       rs540289118       rs541252855       rs541285963       rs542044503       rs542455779       rs542471465       rs542501207       rs542642642       rs543027571       rs543093037       rs543279290       rs543280320       rs543313395       rs543773761       rs544192069       rs544221967       rs544509272       rs544644324       rs544707678       rs544845582       rs544930074       rs545307384       rs545464135       rs545476569       rs545535658       rs545596325       rs545826780       rs546407919       rs546664064       rs546664448       rs546859287       rs546890878       rs547058848       rs547239741       rs547566333       rs547916733       rs548220559       rs548430481       rs548752529       rs549213006       rs549531983       rs550151082       rs550477818       rs550750534       rs550790302       rs550847569       rs550928131       rs550959334       rs550991573       rs551141337       rs551269875       rs551461288       rs551594425       rs551781734       rs552011089       rs552074595       rs552947458       rs552961685       rs553288244       rs554232009       rs554342401       rs554406744       rs554527957       rs554671407       rs554738417       rs555133587       rs555465458       rs555677441       rs555953851       rs555973403       rs556116189       rs556130263       rs556728175       rs557057466       rs557140788       rs557538069       rs558064907       rs558538054       rs558621262       rs558712741       rs559048047       rs559510730       rs559875857       rs560050436       rs560480477       rs560487611       rs560740844       rs560794764       rs561515019       rs561657086       rs561670620       rs561875291       rs561988779       rs562071321       rs562131464       rs562336695       rs562672981       rs562724655       rs562827650       rs562891821       rs562922187       rs563737016       rs563945240       rs564242491       rs564688489       rs565288553       rs565357684       rs565622769       rs565872410       rs566509837       rs567023784       rs567083154       rs567084994       rs567801828       rs567867002       rs568130605       rs568319672       rs568918036       rs569004689       rs569115867       rs569582538       rs569833888       rs569898659       rs570044265       rs570465839       rs570526795       rs570883833       rs570973183       rs571774527       rs571988260       rs571988557       rs572049836       rs572372154       rs572550195       rs572615315       rs572951960       rs573014798       rs573427764       rs573529339       rs573761150       rs574056040       rs574835720       rs575010605       rs575241117       rs576128350       rs576155663       rs576267534       rs576355384       rs576441714       rs576663586       rs576675629       rs577158968       rs577525503       rs577540067       rs577651728       rs577738247       rs578065533       rs578127888       rs745373429       rs746766805       rs747176447       rs748036601       rs748498139       rs748593186       rs748635891       rs749076733       rs749370259       rs749423281       rs750050315       rs750750366       rs751837333       rs751968707       rs752014187       rs753149434       rs753404431       rs754254437       rs755498165       rs755815078       rs756841230       rs757041296       rs757577131       rs758971358       rs760121702       rs760304629       rs762679777       rs762917889       rs763924881       rs764536658       rs765854461       rs765942505       rs767113562       rs767268206       rs768713317       rs768766138       rs769870289       rs770877929       rs771197909       rs771571890       rs771764450       rs771848673       rs772383036       rs772748613       rs773440544       rs774348570       rs774403450       rs775062388       rs775303084       rs776233183       rs776640745       rs777653050       rs778237759       rs778875639       rs779013881       rs779316088       rs780121251       rs780786010       rs781294433       rs781452810       rs781553180       rs796956481      

基因表达

基因表达

H3F3A基因在不同组织中的表达：    [UniProt]

基因在不同组织中的表达图

基因引物

基因引物

正向引物序列
正向引物Tm值
反向引物序列
反向引物Tm值
rank
GAAGAAACCTCATCGTTACAGG
59
CTGATAACGTCTAATTTCACGG
57
TGAAGAAACCTCATCGTTACAG
59
CTGATAACGTCTAATTTCACGG
57
GGTGAAGAAACCTCATCGT
58
ATAACGTCTAATTTCACGGAGC
59
GAAGAAACCTCATCGTTACAGG
59
CTGATAACGTCTAATTTCACGGAG
60
GGGTGAAGAAACCTCATCG
58
TAACGTCTAATTTCACGGAGC
59
GGGTGAAGAAACCTCATCG
58
TAACGTCTAATTTCACGGAGC
59
GGTGAAGAAACCTCATCGT
58
ATAACGTCTAATTTCACGGAGC
59
TGAAGAAACCTCATCGTTACAG
59
CTGATAACGTCTAATTTCACGG
57
TTACAGGCCTGGTACTGTG
59
AGAAGTTCAGTGGACTTCTG
57
GGGTGAAGAAACCTCATCG
58
TAACGTCTAATTTCACGGAGC
59

转录因子

转录因子

      尚未收录相关数据

基因本体信息

H3F3A基因（以及对应的蛋白质）的细胞分布位置：

[UniProt]     [GenomeNet]

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • 溶酶体
  • 内涵体
  • 细胞核
  • 细胞质
  • 液泡
  • 细胞膜
  • 细胞外基质
  • 内质网
  • 线粒体
  • 高尔基体
  • 细胞骨架

H3F3A基因的本体（GO）信息：

GO库代码
对应的蛋白质
来源代码
GO:0000786
B4DEB1(UniProtKB)
IEA
GO:0003677
B4DEB1(UniProtKB)
IEA
GO:0005634
B4DEB1(UniProtKB)
IEA
GO:0046982
B4DEB1(UniProtKB)
IEA
GO:0000183
P84243(UniProtKB)
TAS
GO:0000183
P84243(UniProtKB)
TAS
GO:0000228
P84243(UniProtKB)
IDA
GO:0000784
P84243(UniProtKB)
IDA
GO:0000784
P84243(UniProtKB)
IDA
GO:0000786
P84243(UniProtKB)
IDA
GO:0000786
P84243(UniProtKB)
IDA
GO:0000788
P84243(UniProtKB)
IDA
GO:0000979
P84243(UniProtKB)
IDA
GO:0000980
P84243(UniProtKB)
IDA
GO:0005515
P84243(UniProtKB)
IPI
GO:0005515
P84243(UniProtKB)
IPI
GO:0005515
P84243(UniProtKB)
IPI
GO:0005515
P84243(UniProtKB)
IPI
GO:0005515
P84243(UniProtKB)
IPI
GO:0005515
P84243(UniProtKB)
IPI
GO:0005515
P84243(UniProtKB)
IPI
GO:0005515
P84243(UniProtKB)
IPI
GO:0005515
P84243(UniProtKB)
IPI
GO:0005515
P84243(UniProtKB)
IPI
GO:0005576
P84243(UniProtKB)
TAS
GO:0005634
P84243(UniProtKB)
IDA
GO:0005634
P84243(UniProtKB)
IDA
GO:0005654
P84243(UniProtKB)
TAS
GO:0005654
P84243(UniProtKB)
TAS
GO:0005654
P84243(UniProtKB)
TAS
GO:0005654
P84243(UniProtKB)
TAS
GO:0005654
P84243(UniProtKB)
TAS
GO:0005654
P84243(UniProtKB)
TAS
GO:0005654
P84243(UniProtKB)
TAS
GO:0005654
P84243(UniProtKB)
TAS
GO:0005654
P84243(UniProtKB)
TAS
GO:0005654
P84243(UniProtKB)
TAS
GO:0005654
P84243(UniProtKB)
TAS
GO:0005654
P84243(UniProtKB)
TAS
GO:0005654
P84243(UniProtKB)
TAS
GO:0005654
P84243(UniProtKB)
TAS
GO:0005654
P84243(UniProtKB)
TAS
GO:0005654
P84243(UniProtKB)
TAS
GO:0005654
P84243(UniProtKB)
TAS
GO:0005654
P84243(UniProtKB)
TAS
GO:0005654
P84243(UniProtKB)
TAS
GO:0005654
P84243(UniProtKB)
TAS
GO:0005654
P84243(UniProtKB)
TAS
GO:0005654
P84243(UniProtKB)
TAS
GO:0005654
P84243(UniProtKB)
TAS
GO:0005654
P84243(UniProtKB)
TAS
GO:0005654
P84243(UniProtKB)
TAS
GO:0005654
P84243(UniProtKB)
TAS
GO:0005654
P84243(UniProtKB)
TAS
GO:0005654
P84243(UniProtKB)
TAS
GO:0005654
P84243(UniProtKB)
TAS
GO:0005654
P84243(UniProtKB)
TAS
GO:0005654
P84243(UniProtKB)
TAS
GO:0006334
P84243(UniProtKB)
IDA
GO:0006334
P84243(UniProtKB)
IMP
GO:0006336
P84243(UniProtKB)
IDA
GO:0007420
P84243(UniProtKB)
IEA
GO:0007596
P84243(UniProtKB)
TAS
GO:0009725
P84243(UniProtKB)
IEA
GO:0030307
P84243(UniProtKB)
IMP
GO:0031047
P84243(UniProtKB)
TAS
GO:0031492
P84243(UniProtKB)
IDA
GO:0032200
P84243(UniProtKB)
TAS
GO:0042393
P84243(UniProtKB)
IPI
GO:0043234
P84243(UniProtKB)
IDA
GO:0044267
P84243(UniProtKB)
TAS
GO:0045814
P84243(UniProtKB)
TAS
GO:0045815
P84243(UniProtKB)
TAS
GO:0046982
P84243(UniProtKB)
IEA
GO:0070062
P84243(UniProtKB)
IDA
GO:0070062
P84243(UniProtKB)
IDA

基因相互作用关系

基因相互作用关系

基因与其他基因之间的相互作用关系图
序号 作用方式 资源库来源/分值 基因名称 基因名称

基因相关microRNA

基因相关microRNA

可能调控H3F3A基因的相关microRNA：     

基因通路图

基因通路图

基因的通路属性图
通路基因列表

基因相关疾病

基因相关疾病

疾病名称 关系值 NofPmids NofSnps 来源
疾病名称 关系值 NofPmids NofSnps 来源
Glioblastoma 0.123257302 13 0 BeFree_CTD_human
Glioma 0.122985861 13 0 BeFree_CTD_human
Giant Cell Tumor of Bone 0.120814326 3 0 BeFree_CTD_human
Chondroblastoma 0.000814326 3 0 BeFree
Astrocytoma 0.000542884 2 0 BeFree
Diffuse Intrinsic Pontine Glioma 0.000542884 2 0 BeFree
Brain Neoplasms 0.000271442 1 0 BeFree
Giant Cell Tumors 0.000271442 1 0 BeFree
Degenerative polyarthritis 0.000271442 1 0 BeFree
Central Nervous System Neoplasms 0.000271442 1 0 BeFree
Malignant neoplasm of brain 0.000271442 1 0 BeFree
childhood brain tumor 0.000271442 1 0 BeFree
Telangiectatic osteosarcoma 0.000271442 1 0 BeFree
Malignant Childhood Neoplasm 0.000271442 1 0 BeFree
adult glioblastoma 0.000271442 1 0 BeFree
high-grade childhood cerebral astrocytoma 0.000271442 1 0 BeFree
Anaplastic astrocytoma 0.000271442 1 0 BeFree
Carcinogenesis 0.000271442 1 0 BeFree
Oligodendroglial Neoplasm 0.000271442 1 0 BeFree
Thalamic Neoplasm 0.000271442 1 0 BeFree
ALPHA-THALASSEMIA/MENTAL RETARDATION SYNDROME, NONDELETION TYPE, X-LINKED 0.000271442 1 0 BeFree
Tumors in children 0.000271442 1 0 BeFree

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