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This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor (GPCR) superfamily. The receptors are seven-pass transmembrane proteins that respond to extracellular cues and activate intracellular signal transduction pathways. This protein was reported to be a receptor for lysophosphatidylcholine action, but PubMedID: 15653487 retracts this finding and instead suggests this protein to be an effector of lysophosphatidylcholine action. This protein may have proton-sensing activity and may be a receptor for oxidized free fatty acids. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
[中文简述(自动翻译):]  该基因编码的鸟嘌呤核苷酸 - 结合蛋白的一个成员(G蛋白)偶联的受体(GPCR)超家族。该受体是细胞外线索响应并激活细胞内信号转导途径七次跨膜蛋白。这种蛋白质据报道,为溶血磷脂酰胆碱作用的受体,但PubMedID:15653487缩回这一发现,而是表明该蛋白质是溶血磷脂酰胆碱作用的效应。这种蛋白质可以具有质子传感活性和可以是用于氧化的游离脂肪酸的受体。选择性剪接结果在多个抄本变形。 [由RefSeq的,2013年7月提供]
GPR132基因(以及对应的蛋白质)的细胞分布位置:
GPR132基因的本体(GO)信息:
| 疾病名称 | 关系值 | NofPmids | NofSnps | 来源 |
| Autoimmune Diseases | 0.08 | 0 | 0 | MGD |
| Atherosclerosis | 0.002367032 | 1 | 0 | GAD |
| Lupus Erythematosus, Systemic | 0.002367032 | 1 | 0 | GAD |
| Squamous cell carcinoma | 0.000271442 | 1 | 0 | BeFree |
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