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This gene encodes a mitochondrial enzyme which prefers saturated fatty acids as its substrate for the synthesis of glycerolipids. This metabolic pathway's first step is catalyzed by the encoded enzyme. Two forms for this enzyme exist, one in the mitochondria and one in the endoplasmic reticulum. Two alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Oct 2011]
[中文简述(自动翻译):]  此基因编码宁愿饱和脂肪酸作为其甘油脂的合成基板的线粒体酶。此代谢途径的第一个步骤是通过将编码的酶催化。两种形式对这种酶的存在,一个在线粒体中,一个在内质网。两种可变剪接转录物变体已被用于这个基因说明。 [由RefSeq的,2011年10月提供]
GPAM基因(以及对应的蛋白质)的细胞分布位置:
GPAM基因的本体(GO)信息:
| 疾病名称 | 关系值 | NofPmids | NofSnps | 来源 |
| Diabetes Mellitus, Experimental | 0.12 | 1 | 0 | CTD_human |
| melanoma | 0.12 | 1 | 0 | CTD_human |
| Nephrotic Syndrome | 0.08 | 1 | 0 | RGD |
| Obesity | 0.08 | 1 | 0 | RGD |
| Alzheimer's Disease | 0.002367032 | 1 | 0 | GAD |
| Diabetes Mellitus, Non-Insulin-Dependent | 0.002367032 | 1 | 0 | GAD |
| Fatty Liver | 0.000271442 | 1 | 0 | BeFree |
| Steatohepatitis | 0.000271442 | 1 | 0 | BeFree |
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