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This gene encodes a Golgi protein with a PDZ domain. The PDZ domain is globular and proteins which contain them bind other proteins through short motifs near the C-termini. Mice which are deficient in the orthologous protein have globozoospermia and are infertile. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
[中文简述(自动翻译):]  该基因编码一个PDZ结构域高尔基体蛋白。 PDZ结构域是球状和含有它们的蛋白质通过C末端短附近绑定图案的其他蛋白质。小鼠这是在直系同源蛋白质缺乏有globozoospermia和不育。已发现该基因编码不同亚型的多个抄本变形。 [由RefSeq的,2011年12月提供]
GOPC基因(以及对应的蛋白质)的细胞分布位置:
GOPC基因的本体(GO)信息:
疾病名称 | 关系值 | NofPmids | NofSnps | 来源 |
melanoma | 0.12 | 1 | 0 | CTD_human |
Globozoospermia | 0.08 | 0 | 0 | MGD |
Mucocutaneous Lymph Node Syndrome | 0.002442977 | 9 | 0 | BeFree |
Lip and Oral Cavity Carcinoma | 0.001357209 | 5 | 0 | BeFree |
Malignant neoplasm of mouth | 0.001085767 | 4 | 0 | BeFree |
Exanthema | 0.000814326 | 3 | 0 | BeFree |
Neoplasm Metastasis | 0.000814326 | 3 | 0 | BeFree |
Spots on skin | 0.000814326 | 3 | 0 | BeFree |
Malignant neoplasm of breast | 0.000542884 | 2 | 0 | BeFree |
neurofibroma | 0.000542884 | 2 | 0 | BeFree |
Nerve Sheath Tumors | 0.000542884 | 2 | 0 | BeFree |
Anaplastic thyroid carcinoma | 0.000542884 | 2 | 0 | BeFree |
alpha^0^ Thalassemia | 0.000542884 | 2 | 0 | BeFree |
Squamous cell carcinoma of tongue | 0.000542884 | 2 | 0 | BeFree |
Breast Carcinoma | 0.000542884 | 2 | 0 | BeFree |
Colorectal Carcinoma | 0.000271442 | 1 | 0 | BeFree |
Epilepsy | 0.000271442 | 1 | 0 | BeFree |
Gingival Diseases | 0.000271442 | 1 | 0 | BeFree |
Glioblastoma | 0.000271442 | 1 | 0 | BeFree |
Glioma | 0.000271442 | 1 | 0 | BeFree |
Herpes Simplex Infections | 0.000271442 | 1 | 0 | BeFree |
Chronic Lymphocytic Leukemia | 0.000271442 | 1 | 0 | BeFree |
Lymphoma, Non-Hodgkin | 0.000271442 | 1 | 0 | BeFree |
Measles | 0.000271442 | 1 | 0 | BeFree |
Multiple Myeloma | 0.000271442 | 1 | 0 | BeFree |
Neurofibromatosis 1 | 0.000271442 | 1 | 0 | BeFree |
Osteosarcoma | 0.000271442 | 1 | 0 | BeFree |
Periodontal Diseases | 0.000271442 | 1 | 0 | BeFree |
Thyroid Neoplasm | 0.000271442 | 1 | 0 | BeFree |
Oral Cavity Carcinoma | 0.000271442 | 1 | 0 | BeFree |
Adenosquamous carcinoma | 0.000271442 | 1 | 0 | BeFree |
Gallbladder Carcinoma | 0.000271442 | 1 | 0 | BeFree |
Malignant neoplasm of lung | 0.000271442 | 1 | 0 | BeFree |
Coronary arteritis | 0.000271442 | 1 | 0 | BeFree |
Multiple adenomatous polyps | 0.000271442 | 1 | 0 | BeFree |
Follicular neoplasm | 0.000271442 | 1 | 0 | BeFree |
Papillary neoplasm | 0.000271442 | 1 | 0 | BeFree |
Secondary malignant neoplasm of liver | 0.000271442 | 1 | 0 | BeFree |
Osteosarcoma of bone | 0.000271442 | 1 | 0 | BeFree |
Carcinoma of lung | 0.000271442 | 1 | 0 | BeFree |
Bile duct carcinoma | 0.000271442 | 1 | 0 | BeFree |
Urban Schosser Spohn syndrome | 0.000271442 | 1 | 0 | BeFree |
Blastic plasmacytoid dendritic cell neoplasm | 0.000271442 | 1 | 0 | BeFree |
Glioblastoma Multiforme | 0.000271442 | 1 | 0 | BeFree |
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