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The protein encoded by this gene is a preproprotein that is cleaved to form a secreted 10 aa peptide hormone. The secreted decapeptide regulates reproduction in females by stimulating the secretion of both luteinizing- and follicle-stimulating hormones. Three transcript variants that encode unique proproteins but the same peptide hormone have been found for this gene. [provided by RefSeq, Jul 2008]
[中文简述(自动翻译):]  由该基因编码的蛋白是被裂解以形成分泌10个氨基酸的肽激素前原。分泌的十肽通过刺激既luteinizing-和促卵泡激素的分泌调节雌性生殖。编码独特的原蛋白,但相同的肽类激素三个抄本变形也发现了这种基因。 [由RefSeq的,2008年7月提供]
GNRH2基因(以及对应的蛋白质)的细胞分布位置:
GNRH2基因的本体(GO)信息:
疾病名称 | 关系值 | NofPmids | NofSnps | 来源 |
Fibroid Tumor | 0.002995792 | 1 | 0 | BeFree_LHGDN |
Prostatic Neoplasms | 0.00272435 | 1 | 0 | LHGDN |
Epithelial ovarian cancer | 0.002638474 | 2 | 0 | BeFree_GAD |
Tobacco Use Disorder | 0.002367032 | 1 | 0 | GAD |
Ovarian Carcinoma | 0.001628651 | 6 | 0 | BeFree |
Malignant neoplasm of ovary | 0.001628651 | 6 | 0 | BeFree |
Malignant neoplasm of prostate | 0.000542884 | 2 | 0 | BeFree |
Prostate carcinoma | 0.000542884 | 2 | 0 | BeFree |
Uterine Fibroids | 0.000271442 | 1 | 0 | BeFree |
Staring | 0.000271442 | 1 | 0 | BeFree |
ovarian neoplasm | 0.000271442 | 1 | 0 | BeFree |
Xenograft Model | 0.000271442 | 1 | 0 | BeFree |
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