GMPPB(GDP-mannose pyrophosphorylase B)

基因基本信息

基因基本信息

基因简称(symbol)
    [HGNC]     [GeneCards]     [NCBI]
基因种类(locus group)
同源简称(alias symbol)
基因家族代码(gene_family_id)
    [HGNC]     [GenScript]
omim代码
entrez码
    [Vega]
vega基因码
ensembl基因码
    [Ensembl]
基因家族(gene family)
refseq数据库代号

更多...

基因种类(locus_type)
基因名称状态(status)
location_sortable
同源基因名称(alias name)
基因名称批准使用时间(date_approved_reserved)
基因简称更名时间(date_symbol_changed)
基因名称更名时间(date_name_changed)
更新时间(date_modified)
ucsc码
ena
ccds数据码
uniprot数据码
pubmed代码
mgd码
rgd码
生命科学数据库(lsdb)
更新时间(date modified)
cosmic
mirbase
基因曾用简称(prev symbol)
基因曾用名称(prev name)
homeodb
cosmic
snornabase
bioparadigms slc
orphanet
假基因信息(pseudogeneorg)
horde id
merops
imgt
iuphar
kznf基因类别
mamit-trnadb
cd
LncRNA数据库
酶代码
中间纤维数据库

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基因染色体位置

基因染色体位置

3p21.31
基因染色体位置图

基因简述

基因简述

This gene is thought to encode a GDP-mannose pyrophosphorylase. The encoded protein catalyzes the conversion of mannose-1-phosphate and GTP to GDP-mannose, a reaction involved in the production of N-linked oligosaccharides. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jan 2009]

[中文简述(自动翻译):]  该基因被认为编码GDP甘露糖焦磷酸化酶。所编码的蛋白质催化甘露糖-1-磷酸和GTP与GDP甘露糖，涉及生产N-连接的寡糖的反应的转化率。编码不同同种型的可变剪接转录物变体已有描述。 [由RefSeq的，2009年1月提供]

OMIM数据库中对GMPPB基因的介绍     Wikipedia数据库中对GMPPB基因的介绍

基因序列

基因序列

GMPPB基因的碱基序列：[NCBI]

基因突变

基因突变

GMPPB基因的碱基突变：           显示全部snp
rs4768       rs1046598       rs34127462       rs74944821       rs114836451       rs139041816       rs143218268       rs146833478       rs150039459       rs150478395       rs184127567       rs185245937       rs192049545       rs199933786       rs200170860       rs200992117       rs202151835       rs367730914       rs367820087       rs370738203       rs371254158       rs372037773       rs372660006       rs374989197       rs375127888       rs375162605       rs376781574       rs531884204       rs536640332       rs536698208       rs540925580       rs543835310       rs548803801       rs561212361       rs565233253       rs565395732       rs566389723      
rs570077731       rs576430897       rs745723851       rs746010368       rs746311869       rs746571282       rs746616705       rs747396171       rs747609414       rs748150598       rs748602635       rs749169504       rs749437523       rs749717135       rs750006351       rs750733949       rs750890694       rs750946450       rs751080607       rs751205274       rs751983113       rs752119240       rs752265029       rs752804068       rs752921207       rs753601376       rs753894718       rs753981644       rs754581862       rs754623460       rs755193049       rs755415446       rs756679856       rs757051847       rs757255509       rs757351286       rs757787801       rs757971205       rs758635934       rs758714142       rs758914199       rs759206917       rs759826409       rs760277235       rs760282130       rs760594406       rs760786484       rs761843939       rs762877060       rs763003314       rs763441995       rs763537586       rs763596393       rs763999469       rs764087552       rs764339738       rs766105816       rs766197099       rs766199435       rs767453255       rs767792476       rs768685100       rs768883407       rs769459081       rs769831352       rs770434747       rs770808633       rs771004770       rs771149753       rs771150955       rs771602675       rs771861177       rs772250566       rs772340064       rs773247466       rs773696343       rs775745330       rs776117691       rs776272984       rs776387687       rs777742770       rs777939894       rs778461928       rs779044341       rs779088445       rs780341885       rs780456158       rs780870009       rs781037630       rs781514065       rs1049256       rs1049257       rs1466685       rs1803430       rs2131106       rs2291543       rs3811695       rs3811696       rs4855850       rs7634902       rs11547261       rs11709076       rs11716895       rs17598300       rs17598341       rs17598404       rs34345884       rs55816606       rs71324991       rs71324992       rs113739009       rs114745265       rs115258065       rs116774792       rs138421654       rs138664819       rs139668958       rs140427047       rs140509231       rs140864960       rs140968388       rs141074520       rs141201072       rs141588721       rs142336618       rs142451427       rs142908436       rs144040971       rs144305518       rs144421130       rs144667181       rs145535498       rs145564018       rs145671483       rs146287156       rs147074020       rs147516683       rs147672249       rs147714661       rs147966522       rs148249248       rs148826912       rs150149795       rs151016106       rs182316812       rs183240200       rs184487665       rs186586241       rs187185691       rs191646881       rs191912441       rs192220325       rs199580664       rs199922550       rs200085944       rs200287431       rs200384032       rs200511393       rs201000786       rs201109088       rs201123231       rs201260267       rs201670162       rs201729050       rs201795833       rs202013297       rs202160208       rs368344694       rs368542417       rs368616628       rs368795315       rs368799173       rs369255307       rs369648438       rs369862012       rs370203820       rs370448223       rs370840899       rs371035120       rs371188899       rs371525780       rs371668864       rs371850986       rs371972364       rs372202034       rs372512288       rs372563869       rs372736168       rs373153608       rs373392696       rs373531243       rs373645292       rs373693597       rs373707045       rs374270205       rs374491667       rs374497499       rs374586408       rs375299725       rs375490823       rs375618039       rs375887616       rs376121229       rs376367401       rs376726739       rs377229538       rs377262833       rs377689496       rs397509422       rs397509425       rs397509426       rs527464553       rs527636452       rs528688224       rs528861004       rs529043513       rs531383650       rs531418495       rs533212703       rs533769052       rs534183746       rs534685803       rs535123551       rs535449660       rs535694871       rs538469063       rs539472886       rs539620720       rs539632278       rs540500622       rs540816699       rs541060793       rs541447888       rs542083837       rs543993079       rs544286665       rs544711341       rs545985873       rs546047482       rs548945395       rs549227034       rs549264083       rs549676455       rs550636454       rs551625766       rs551707308       rs551861024       rs553207329       rs553408857       rs556037932       rs558029172       rs558185676       rs558411419       rs559649410       rs559784211       rs559848548       rs562593870       rs562635272       rs563622384       rs563660419       rs563829852       rs564655211       rs566681464       rs568493684       rs568539552       rs568878689       rs569041128       rs569168544       rs570239663       rs571690276       rs573360685       rs573493875       rs573842148       rs574291004       rs577851636       rs745690104       rs745989159       rs746118453       rs746357591       rs746420101       rs746692553       rs746951712       rs747150735       rs747427232       rs747548054       rs747728635       rs747818187       rs747845961       rs748124590       rs748270661       rs748301983       rs748350135       rs748690853       rs748790218       rs748809549       rs748814822       rs748848527       rs749261861       rs749410478       rs749730219       rs749927415       rs750017093       rs750052068       rs750310103       rs750488885       rs750530833       rs750761843       rs751336882       rs751351362       rs751418648       rs751734172       rs751931232       rs752035463       rs752053591       rs752225822       rs752457623       rs752558648       rs752598051       rs752805529       rs753014812       rs753170031       rs753366203       rs753456540       rs753463106       rs753722732       rs754131827       rs754181889       rs754267908       rs754331565       rs754597337       rs754721878       rs754911891       rs754917786       rs755165049       rs755508006       rs755513889       rs755598141       rs755758590       rs755806372       rs755951550       rs756092989       rs756215708       rs756344903       rs756463595       rs756576625       rs756596742       rs756662069       rs756682220       rs756852893       rs757186552       rs757442379       rs757709801       rs757929839       rs758087760       rs758284245       rs758354311       rs758366693       rs758587073       rs758606902       rs758710072       rs758943375       rs758950585       rs759137392       rs759453935       rs759457711       rs759478164       rs759988950       rs760226456       rs760240362       rs760516067       rs760610690       rs760967310       rs760984317       rs761324186       rs761365873       rs761570774       rs761577278       rs761714818       rs761748300       rs762013086       rs762098688       rs762117823       rs762472949       rs762520709       rs762703013       rs762790429       rs762987523       rs762995747       rs763262592       rs763452482       rs763737299       rs763825301       rs763971677       rs764211532       rs764253773       rs764450464       rs764575305       rs764625823       rs764824225       rs764979130       rs765143269       rs765169109       rs765317497       rs765351932       rs765388198       rs765514162       rs765573379       rs765589830       rs765625160       rs765840859       rs765860505       rs766144577       rs766298888       rs766340945       rs766498097       rs766681574       rs766831711       rs766857827       rs766986329       rs767334898       rs767418968       rs767675803       rs767949835       rs768115410       rs768175595       rs768327938       rs768704043       rs769076864       rs769164977       rs769346834       rs769641702       rs769730706       rs769882635       rs769914373       rs770010003       rs770117250       rs770556548       rs770879712       rs771025862       rs771028755       rs771239680       rs771412553       rs771594203       rs771732077       rs772099238       rs772116517       rs772511554       rs772763615       rs772824443       rs772962321       rs773158417       rs773215409       rs773307667       rs773396939       rs773627734       rs773705196       rs773881356       rs774007262       rs774179466       rs774235000       rs774498980       rs774786641       rs774920371       rs775034121       rs775118468       rs775357256       rs775456047       rs775559778       rs775798814       rs775910135       rs776127816       rs776256267       rs776779111       rs776829587       rs776871687       rs776950715       rs777150806       rs777323266       rs777330041       rs777727126       rs777909174       rs778007587       rs778275046       rs778386041       rs778490288       rs778568517       rs778763772       rs778764067       rs778959425       rs779167148       rs779282462       rs779522830       rs779737240       rs779826259       rs780101907       rs780301264       rs780657551       rs780867515       rs780875521       rs780949495       rs780992120       rs781114909       rs781132109       rs781224121       rs781404642       rs781777729      

基因表达

基因表达

GMPPB基因在不同组织中的表达：    [UniProt]

基因在不同组织中的表达图

基因引物

基因引物

正向引物序列
正向引物Tm值
反向引物序列
反向引物Tm值
rank
ATGAAGAGGAGCCTTTGGG
59
AGAAAGGGTCTGCAGTCTC
59
GCTGGAGAAGGAAATGAAGG
59
ATGGGACATGGAGATTCGG
59
CCTACGTCCATTGAGAAGGA
59
TCCAGAAGCCCTGTAACTC
59
CCTACGTCCATTGAGAAGGA
59
TCCAGAAGCCCTGTAACTC
59
TACGTCCATTGAGAAGGAGG
59
ATCCAGAAGCCCTGTAACTC
59
TGGAGAAGGAAATGAAGGCA
59
TCATGGGACATGGAGATTCG
60
TGGAGTTACAGGGCTTCTG
59
TCAGTGACTGCAGGAAGAG
59
CCTACGTCCATTGAGAAGGA
59
TCCAGAAGCCCTGTAACTC
59
TGGAGTTACAGGGCTTCTG
59
TCAGTGACTGCAGGAAGAG
59
TACGTCCATTGAGAAGGAGG
59
ATCCAGAAGCCCTGTAACTC
59

转录因子

转录因子

      尚未收录相关数据

基因本体信息

GMPPB基因（以及对应的蛋白质）的细胞分布位置：

[UniProt]     [GenomeNet]

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • 溶酶体
  • 内涵体
  • 细胞核
  • 细胞质
  • 液泡
  • 细胞膜
  • 细胞外基质
  • 内质网
  • 线粒体
  • 高尔基体
  • 细胞骨架

GMPPB基因的本体（GO）信息：

GO库代码
对应的蛋白质
来源代码
GO:0004475
Q9Y5P6(UniProtKB)
IEA
GO:0005515
Q9Y5P6(UniProtKB)
IPI
GO:0005515
Q9Y5P6(UniProtKB)
IPI
GO:0005515
Q9Y5P6(UniProtKB)
IPI
GO:0005525
Q9Y5P6(UniProtKB)
IEA
GO:0005737
Q9Y5P6(UniProtKB)
IDA
GO:0005739
Q9Y5P6(UniProtKB)
IEA
GO:0009298
Q9Y5P6(UniProtKB)
IEA
GO:0070062
Q9Y5P6(UniProtKB)
IDA

基因相互作用关系

基因相互作用关系

基因与其他基因之间的相互作用关系图
序号 作用方式 资源库来源/分值 基因名称 基因名称

基因相关microRNA

基因相关microRNA

可能调控GMPPB基因的相关microRNA：     

基因通路图

基因通路图

基因的通路属性图
通路基因列表

基因相关疾病

基因相关疾病

疾病名称 关系值 NofPmids NofSnps 来源
疾病名称 关系值 NofPmids NofSnps 来源
MUSCULAR DYSTROPHY-DYSTROGLYCANOPATHY (LIMB-GIRDLE), TYPE C, 14 0.36 1 5 CLINVAR_ORPHANET_UNIPROT
MUSCULAR DYSTROPHY-DYSTROGLYCANOPATHY (CONGENITAL WITH BRAIN AND EYE ANOMALIES), TYPE A, 14 0.24 1 3 CLINVAR_UNIPROT
MUSCULAR DYSTROPHY-DYSTROGLYCANOPATHY (CONGENITAL WITH MENTAL RETARDATION), TYPE B, 14 0.24 1 3 CLINVAR_UNIPROT
Muscle eye brain disease 0.12 0 0 ORPHANET
Crohn Disease 0.002367032 1 0 GAD
Muscular Dystrophies, Limb-Girdle 0.000814326 3 0 BeFree
Epilepsy, Generalized 0.000271442 1 0 BeFree
Muscular Dystrophy 0.000271442 1 0 BeFree
Congenital muscular dystrophy (disorder) 0.000271442 1 0 BeFree
Myasthenic Syndromes, Congenital 0.000271442 1 0 BeFree
alpha-Dystroglycanopathies 0.000271442 1 0 BeFree
Intellectual Disability 0.000271442 1 0 BeFree

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