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The glycine-N-acyltransferase protein conjugates glycine with acyl-CoA substrates in the mitochondria. The protein is thought to be important in the detoxification of endogenous and xenobiotic acyl-CoA's. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
[中文简述(自动翻译):]  甘氨酸-N-酰基转移酶蛋白偶联物与线粒体酰基辅酶A底物的甘氨酸。该蛋白被认为是内源性和外源性酰基-CoA的解毒重要。已发现该基因编码不同亚型的两个转录变异体。 [由RefSeq的,2008年7月提供]
GLYAT基因(以及对应的蛋白质)的细胞分布位置:
GLYAT基因的本体(GO)信息:
疾病名称 | 关系值 | NofPmids | NofSnps | 来源 |
HIV Infections | 0.006243163 | 23 | 0 | BeFree |
Liver carcinoma | 0.005157396 | 19 | 0 | BeFree |
Liver neoplasms | 0.004071628 | 15 | 0 | BeFree |
Malignant neoplasm of breast | 0.003800186 | 14 | 2 | BeFree |
Breast Carcinoma | 0.003800186 | 14 | 2 | BeFree |
Neuroblastoma | 0.001357209 | 5 | 0 | BeFree |
Thalassemia | 0.001357209 | 5 | 0 | BeFree |
Prostate carcinoma | 0.001357209 | 5 | 0 | BeFree |
Central neuroblastoma | 0.001357209 | 5 | 0 | BeFree |
Mammary Neoplasms | 0.001357209 | 5 | 0 | BeFree |
Adenocarcinoma | 0.001085767 | 4 | 0 | BeFree |
Asthma | 0.001085767 | 4 | 0 | BeFree |
Diabetes Mellitus, Non-Insulin-Dependent | 0.001085767 | 4 | 0 | BeFree |
Hepatoblastoma | 0.001085767 | 4 | 0 | BeFree |
Pancreatic carcinoma | 0.001085767 | 4 | 0 | BeFree |
Malignant neoplasm of prostate | 0.001085767 | 4 | 0 | BeFree |
Spinocerebellar Ataxia Type 1 | 0.001085767 | 4 | 0 | BeFree |
Malignant tumor of colon | 0.000814326 | 3 | 0 | BeFree |
Lymphoma | 0.000814326 | 3 | 2 | BeFree |
Pituitary Diseases | 0.000814326 | 3 | 0 | BeFree |
Vitiligo | 0.000814326 | 3 | 0 | BeFree |
Xeroderma Pigmentosum | 0.000814326 | 3 | 0 | BeFree |
Malignant neoplasm of lung | 0.000814326 | 3 | 0 | BeFree |
beta^0^ Thalassemia | 0.000814326 | 3 | 0 | BeFree |
Cervix carcinoma | 0.000814326 | 3 | 0 | BeFree |
Endometrial Carcinoma | 0.000814326 | 3 | 0 | BeFree |
Carcinogenesis | 0.000814326 | 3 | 0 | BeFree |
Carcinoma of lung | 0.000814326 | 3 | 0 | BeFree |
Colon Carcinoma | 0.000814326 | 3 | 0 | BeFree |
VITILIGO-ASSOCIATED MULTIPLE AUTOIMMUNE DISEASE SUSCEPTIBILITY 1 (finding) | 0.000814326 | 3 | 0 | BeFree |
Squamous cell carcinoma | 0.000542884 | 2 | 0 | BeFree |
Choriocarcinoma | 0.000542884 | 2 | 0 | BeFree |
Cockayne Syndrome | 0.000542884 | 2 | 0 | BeFree |
Colorectal Carcinoma | 0.000542884 | 2 | 0 | BeFree |
Diabetes Mellitus, Insulin-Dependent | 0.000542884 | 2 | 0 | BeFree |
Diabetic Nephropathy | 0.000542884 | 2 | 0 | BeFree |
Glioma | 0.000542884 | 2 | 2 | BeFree |
Adult T-Cell Lymphoma/Leukemia | 0.000542884 | 2 | 0 | BeFree |
melanoma | 0.000542884 | 2 | 0 | BeFree |
Degenerative polyarthritis | 0.000542884 | 2 | 0 | BeFree |
Polycythemia | 0.000542884 | 2 | 0 | BeFree |
Aortic Aneurysm, Thoracic | 0.000542884 | 2 | 0 | BeFree |
Anaplastic thyroid carcinoma | 0.000542884 | 2 | 0 | BeFree |
Papillary thyroid carcinoma | 0.000542884 | 2 | 0 | BeFree |
Respiratory syncytial virus (RSV) infection in conditions classified elsewhere and of unspecified site | 0.000542884 | 2 | 0 | BeFree |
Erythrocytosis | 0.000542884 | 2 | 0 | BeFree |
Coronary Artery Disease | 0.000542884 | 2 | 3 | BeFree |
Adenoma | 0.000271442 | 1 | 0 | BeFree |
Alcoholic Intoxication, Chronic | 0.000271442 | 1 | 0 | BeFree |
Amyotrophic Lateral Sclerosis | 0.000271442 | 1 | 0 | BeFree |
Refractory anaemia with excess blasts | 0.000271442 | 1 | 0 | BeFree |
Anxiety Disorders | 0.000271442 | 1 | 0 | BeFree |
Barrett Esophagus | 0.000271442 | 1 | 0 | BeFree |
Bipolar Disorder | 0.000271442 | 1 | 0 | BeFree |
Malignant neoplasm of thyroid | 0.000271442 | 1 | 0 | BeFree |
Mucinous Adenocarcinoma | 0.000271442 | 1 | 0 | BeFree |
Non-Small Cell Lung Carcinoma | 0.000271442 | 1 | 0 | BeFree |
Malignant tumor of cervix | 0.000271442 | 1 | 0 | BeFree |
Cholesterol Ester Storage Disease | 0.000271442 | 1 | 0 | BeFree |
Congenital chromosomal disease | 0.000271442 | 1 | 0 | BeFree |
Cutis Laxa | 0.000271442 | 1 | 0 | BeFree |
Dental Plaque | 0.000271442 | 1 | 0 | BeFree |
Dermatitis, Atopic | 0.000271442 | 1 | 0 | BeFree |
Eczema | 0.000271442 | 1 | 0 | BeFree |
Fragile X Syndrome | 0.000271442 | 1 | 0 | BeFree |
Sensorineural Hearing Loss (disorder) | 0.000271442 | 1 | 0 | BeFree |
Cardiac Arrest | 0.000271442 | 1 | 0 | BeFree |
Hepatitis B | 0.000271442 | 1 | 0 | BeFree |
Hepatolenticular Degeneration | 0.000271442 | 1 | 0 | BeFree |
Herpes Simplex Infections | 0.000271442 | 1 | 0 | BeFree |
Male infertility | 0.000271442 | 1 | 0 | BeFree |
Influenza | 0.000271442 | 1 | 0 | BeFree |
insulinoma | 0.000271442 | 1 | 0 | BeFree |
Kernicterus | 0.000271442 | 1 | 0 | BeFree |
leiomyosarcoma | 0.000271442 | 1 | 0 | BeFree |
leukemia | 0.000271442 | 1 | 0 | BeFree |
Leukoencephalopathy, Progressive Multifocal | 0.000271442 | 1 | 0 | BeFree |
Chronic Obstructive Airway Disease | 0.000271442 | 1 | 0 | BeFree |
Lupus Erythematosus, Systemic | 0.000271442 | 1 | 0 | BeFree |
Lymphoma, Non-Hodgkin | 0.000271442 | 1 | 0 | BeFree |
Malaria | 0.000271442 | 1 | 0 | BeFree |
Malaria, Cerebral | 0.000271442 | 1 | 0 | BeFree |
Malignant neoplasm of stomach | 0.000271442 | 1 | 0 | BeFree |
Measles | 0.000271442 | 1 | 0 | BeFree |
Mental Retardation | 0.000271442 | 1 | 0 | BeFree |
Monosomy | 0.000271442 | 1 | 0 | BeFree |
Neoplasm Metastasis | 0.000271442 | 1 | 0 | BeFree |
Nephroblastoma | 0.000271442 | 1 | 0 | BeFree |
Osteosarcoma | 0.000271442 | 1 | 0 | BeFree |
Ovarian Carcinoma | 0.000271442 | 1 | 0 | BeFree |
Pheochromocytoma | 0.000271442 | 1 | 0 | BeFree |
Pituitary Neoplasms | 0.000271442 | 1 | 0 | BeFree |
Plasmacytoma | 0.000271442 | 1 | 0 | BeFree |
Prostatic Diseases | 0.000271442 | 1 | 3 | BeFree |
Hereditary spherocytosis | 0.000271442 | 1 | 0 | BeFree |
Superinfection | 0.000271442 | 1 | 0 | BeFree |
Vascular Diseases | 0.000271442 | 1 | 0 | BeFree |
Hallopeau-Siemens Disease | 0.000271442 | 1 | 0 | BeFree |
Eosinophilia-Myalgia Syndrome | 0.000271442 | 1 | 0 | BeFree |
Ataxia, Spinocerebellar | 0.000271442 | 1 | 0 | BeFree |
Small cell carcinoma of lung | 0.000271442 | 1 | 0 | BeFree |
Agenesis of corpus callosum | 0.000271442 | 1 | 0 | BeFree |
Embryonal Carcinoma | 0.000271442 | 1 | 0 | BeFree |
Neuroectodermal Tumor, Primitive | 0.000271442 | 1 | 0 | BeFree |
Teratocarcinoma | 0.000271442 | 1 | 0 | BeFree |
Follicular thyroid carcinoma | 0.000271442 | 1 | 0 | BeFree |
Extrapyramidal sign | 0.000271442 | 1 | 0 | BeFree |
Neurologic Symptoms | 0.000271442 | 1 | 1 | BeFree |
Cerebral atrophy | 0.000271442 | 1 | 0 | BeFree |
Medullary carcinoma of thyroid | 0.000271442 | 1 | 0 | BeFree |
Chronic Periodontitis | 0.000271442 | 1 | 0 | BeFree |
Tyrosinemias | 0.000271442 | 1 | 0 | BeFree |
HHH syndrome | 0.000271442 | 1 | 1 | BeFree |
Spastic syndrome | 0.000271442 | 1 | 0 | BeFree |
Severe hereditary factor VIII deficiency disease | 0.000271442 | 1 | 0 | BeFree |
Stage IV Prostate Carcinoma | 0.000271442 | 1 | 1 | BeFree |
Extraosseous Ewings sarcoma-primitive neuroepithelial tumor | 0.000271442 | 1 | 0 | BeFree |
3 beta-Hydroxysteroid dehydrogenase deficiency | 0.000271442 | 1 | 0 | BeFree |
MRSA - Methicillin resistant Staphylococcus aureus infection | 0.000271442 | 1 | 0 | BeFree |
Angiosarcoma of liver | 0.000271442 | 1 | 0 | BeFree |
Malignant neoplasm of pancreas | 0.000271442 | 1 | 0 | BeFree |
Overweight | 0.000271442 | 1 | 0 | BeFree |
Metabolic Syndrome X | 0.000271442 | 1 | 0 | BeFree |
Thyroid carcinoma | 0.000271442 | 1 | 0 | BeFree |
pseudohermaphrodite (non-specific) | 0.000271442 | 1 | 0 | BeFree |
Osteosarcoma of bone | 0.000271442 | 1 | 0 | BeFree |
Ewings sarcoma-primitive neuroectodermal tumor (PNET) | 0.000271442 | 1 | 0 | BeFree |
Stomach Carcinoma | 0.000271442 | 1 | 0 | BeFree |
latent infection | 0.000271442 | 1 | 0 | BeFree |
ovarian neoplasm | 0.000271442 | 1 | 0 | BeFree |
Malignant neoplasm of ovary | 0.000271442 | 1 | 0 | BeFree |
Squamous cell carcinoma of the head and neck | 0.000271442 | 1 | 0 | BeFree |
Ductal Carcinoma | 0.000271442 | 1 | 0 | BeFree |
Diffuse Scleroderma | 0.000271442 | 1 | 0 | BeFree |
Hereditary Nonpolyposis Colorectal Cancer | 0.000271442 | 1 | 0 | BeFree |
Colorectal Cancer | 0.000271442 | 1 | 0 | BeFree |
Ductal Breast Carcinoma | 0.000271442 | 1 | 0 | BeFree |
Amyotrophic Lateral Sclerosis, Sporadic | 0.000271442 | 1 | 0 | BeFree |
SPHEROCYTOSIS, TYPE 1 (disorder) | 0.000271442 | 1 | 0 | BeFree |
Stage IV Prostate Cancer AJCC v7 | 0.000271442 | 1 | 1 | BeFree |
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