GFER(growth factor, augmenter of liver regeneration) 转至新版数据库

基因基本信息

基因基本信息

基因简称(symbol)
    [HGNC]     [GeneCards]     [NCBI]
基因种类(locus group)
同源简称(alias symbol)
基因家族代码(gene_family_id)
    [HGNC]     [GenScript]
omim代码
entrez码
    [Vega]
vega基因码
ensembl基因码
    [Ensembl]
基因家族(gene family)
refseq数据库代号

更多...

基因种类(locus_type)
基因名称状态(status)
location_sortable
同源基因名称(alias name)
基因名称批准使用时间(date_approved_reserved)
基因简称更名时间(date_symbol_changed)
基因名称更名时间(date_name_changed)
更新时间(date_modified)
ucsc码
ena
ccds数据码
uniprot数据码
pubmed代码
mgd码
rgd码
生命科学数据库(lsdb)
更新时间(date modified)
cosmic
mirbase
基因曾用简称(prev symbol)
基因曾用名称(prev name)
homeodb
cosmic
snornabase
bioparadigms slc
orphanet
假基因信息(pseudogeneorg)
horde id
merops
imgt
iuphar
kznf基因类别
mamit-trnadb
cd
LncRNA数据库
酶代码
中间纤维数据库

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基因染色体位置

基因染色体位置

16p13.3-p13.12
基因染色体位置图

基因简述

基因简述

The hepatotrophic factor designated augmenter of liver regeneration (ALR) is thought to be one of the factors responsible for the extraordinary regenerative capacity of mammalian liver. It has also been called hepatic regenerative stimulation substance (HSS). The gene resides on chromosome 16 in the interval containing the locus for polycystic kidney disease (PKD1). The putative gene product is 42% similar to the scERV1 protein of yeast. The yeast scERV1 gene had been found to be essential for oxidative phosphorylation, the maintenance of mitochondrial genomes, and the cell division cycle. The human gene is both the structural and functional homolog of the yeast scERV1 gene. [provided by RefSeq, Jul 2008]

[中文简述(自动翻译):]  肝再生的嗜肝因子指定增强因子（ALR）被认为是负责哺乳动物肝脏的非凡再生能力的因素之一。它也被称为肝再生刺激物质（HSS）中。该基因包含多囊肾病（PKD1）的轨迹区间位于16号染色体上。推定的基因产物是类似于酵母的scERV1蛋白质42％。酵母scERV1基因已被发现是氧化磷酸化，线粒体基因组的维护，并在细胞分裂周期的关键。人类基因既是酵母scERV1基因的结构和功能同系物。 [由RefSeq的，2008年7月提供]

OMIM数据库中对GFER基因的介绍     Wikipedia数据库中对GFER基因的介绍

基因序列

基因序列

GFER基因的碱基序列：[NCBI]

基因突变

基因突变

GFER基因的碱基突变：           显示全部snp
rs1046495       rs1046502       rs1122949       rs1465258       rs1802834       rs2072684       rs2075812       rs2075813       rs2159248       rs2238411       rs2238412       rs2238413       rs2238414       rs3177440       rs3785272       rs3785273       rs3833071       rs4305019       rs4305020       rs11542302       rs11859311       rs11859464       rs11860328       rs11864543       rs12149243       rs12918417       rs12924762       rs12934655       rs13331061       rs17135743       rs17135745       rs28578934       rs28738719       rs34973300       rs35155825       rs36041021       rs56119017      
rs61572004       rs61729106       rs61729107       rs62038788       rs66874200       rs72766611       rs72766612       rs72766613       rs72766615       rs73496038       rs74002752       rs74333711       rs75839330       rs75866428       rs76332338       rs76983878       rs77304208       rs77510740       rs77844279       rs79842623       rs111960608       rs111995953       rs112102156       rs112854675       rs112914759       rs113097793       rs113173128       rs113398284       rs113478901       rs113566304       rs114584528       rs115028126       rs118144645       rs121908192       rs139338021       rs139351234       rs139941314       rs139979014       rs140398555       rs141875432       rs142042300       rs142220504       rs142611193       rs143272026       rs143512788       rs144305234       rs144652758       rs145441654       rs145985630       rs145995643       rs146344112       rs146529877       rs146752626       rs147568500       rs148537045       rs148855968       rs150407325       rs150778136       rs150953401       rs181241477       rs182688114       rs183638147       rs183744268       rs185293217       rs185986846       rs186856814       rs187140560       rs188029304       rs190490143       rs190694551       rs192203480       rs192980891       rs199541169       rs199651600       rs199788169       rs200006442       rs200271594       rs200344292       rs200708108       rs201048650       rs201112184       rs201243520       rs201603991       rs201675904       rs201762532       rs201959073       rs367568477       rs368838564       rs368889722       rs369980955       rs370475970       rs372788926       rs373135339       rs373446345       rs373704476       rs374472317       rs375792737       rs376238901       rs376478434       rs527565190       rs528428688       rs528813454       rs528897932       rs529239322       rs529551959       rs529595412       rs529853737       rs530763802       rs530851220       rs531250292       rs531763312       rs532850984       rs533932776       rs534308773       rs535377905       rs536674789       rs536675524       rs537164723       rs537273406       rs538091471       rs538988050       rs539020780       rs539090541       rs539285000       rs539944730       rs539999840       rs541020575       rs541217652       rs543031717       rs543288469       rs543345314       rs544316670       rs544715752       rs545053910       rs545266207       rs545712726       rs545780953       rs545901614       rs546945191       rs547677664       rs547950368       rs548154709       rs548241046       rs548698978       rs549270205       rs549501017       rs549576465       rs549662382       rs550296574       rs550962998       rs552218964       rs552344160       rs553512894       rs554223803       rs554260646       rs554534173       rs554616847       rs556029488       rs556266225       rs556860495       rs557513682       rs557516955       rs558272206       rs558446706       rs558642302       rs559136249       rs561895771       rs562133653       rs562561911       rs563118183       rs563514338       rs563527259       rs563965614       rs564232412       rs564378951       rs564522189       rs565205569       rs565739180       rs565816111       rs566067616       rs566466090       rs568194761       rs569037883       rs569048447       rs570441231       rs570919437       rs571030170       rs571089283       rs571384984       rs571773678       rs572045152       rs572082575       rs572404227       rs572707478       rs572795585       rs572983282       rs574089740       rs574318592       rs574489077       rs575675080       rs575994898       rs576637429       rs576666874       rs576703936       rs576728754       rs577045077       rs578031217       rs745449861       rs745520506       rs745746499       rs745983562       rs746282425       rs746613040       rs746842124       rs747241374       rs747266786       rs747482644       rs748018775       rs748329975       rs749260043       rs749652504       rs749958872       rs750515991       rs750605745       rs751075413       rs751340896       rs751428853       rs752327413       rs752821388       rs753058591       rs753132528       rs753639816       rs753862865       rs754000227       rs754277823       rs754482090       rs754843277       rs755147804       rs755279097       rs755745663       rs755761266       rs756203483       rs756436660       rs756774007       rs756895320       rs756987474       rs757388602       rs757519057       rs758150888       rs758350837       rs758618799       rs758750318       rs758983119       rs759460274       rs759548245       rs759777543       rs760018110       rs760247120       rs760336801       rs760615529       rs760957301       rs761533080       rs761687015       rs762037327       rs762295209       rs762842175       rs762907502       rs763341760       rs763545328       rs763610770       rs763693977       rs763786791       rs764171720       rs764697486       rs765081796       rs765134997       rs765722914       rs766280079       rs766748062       rs766898922       rs767070180       rs767293111       rs767955242       rs768270980       rs768661163       rs768859031       rs768871809       rs769900445       rs770384334       rs770615093       rs770846566       rs770900182       rs771712671       rs771809901       rs772307688       rs772682634       rs773199934       rs773323504       rs773681926       rs774235374       rs774614929       rs774862313       rs774893508       rs775444384       rs775969329       rs776371765       rs776799405       rs776857102       rs777572484       rs777926923       rs778160972       rs778201726       rs778574653       rs779254345       rs779641464       rs780196676       rs780287282       rs780490309       rs780491791       rs780851934       rs780954807       rs781395247       rs781585682       rs781628694      

基因表达

基因表达

GFER基因在不同组织中的表达：    [UniProt]

基因在不同组织中的表达图

基因引物

基因引物

正向引物序列
正向引物Tm值
反向引物序列
反向引物Tm值
rank
TGAGGAGTGTGCTGAAGAC
59
TTCACTTCATTGTGCAGGT
58
TGAGGAGTGTGCTGAAGAC
59
CACTTCATTGTGCAGGTGG
60
GTCGACTTCAAGACGTGGA
60
AGTCCTCCCTAAACTTGGTG
59
TGAGGAGTGTGCTGAAGAC
59
CACTTCATTGTGCAGGTGG
60
GTCGACTTCAAGACGTGGA
60
CAGTCCTCCCTAAACTTGGT
59
GTCGACTTCAAGACGTGGA
60
CAGTCCTCCCTAAACTTGGT
59
TGAGGAGTGTGCTGAAGAC
59
TCACTTCATTGTGCAGGTG
58
GACTTCAAGACGTGGATGC
59
TCACTTCATTGTGCAGGTG
58
TGAGGAGTGTGCTGAAGAC
59
TCACTTCATTGTGCAGGTG
58
GTCGACTTCAAGACGTGGA
60
AGTCCTCCCTAAACTTGGTG
59

转录因子

转录因子

      尚未收录相关数据

基因本体信息

GFER基因（以及对应的蛋白质）的细胞分布位置：

[UniProt]     [GenomeNet]

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • 溶酶体
  • 内涵体
  • 细胞核
  • 细胞质
  • 液泡
  • 细胞膜
  • 细胞外基质
  • 内质网
  • 线粒体
  • 高尔基体
  • 细胞骨架

GFER基因的本体（GO）信息：

GO库代码
对应的蛋白质
来源代码
GO:0005737
H3BQQ4(UniProtKB)
IDA
GO:0005739
H3BQQ4(UniProtKB)
IDA
GO:0016972
H3BQQ4(UniProtKB)
IEA
GO:0055114
H3BQQ4(UniProtKB)
IEA
GO:0016972
H3BRD2(UniProtKB)
IEA
GO:0055114
H3BRD2(UniProtKB)
IEA
GO:0005515
P55789(UniProtKB)
IPI
GO:0005515
P55789(UniProtKB)
IPI
GO:0005576
P55789(UniProtKB)
IEA
GO:0005737
P55789(UniProtKB)
IDA
GO:0005739
P55789(UniProtKB)
IDA
GO:0005758
P55789(UniProtKB)
IEA
GO:0008083
P55789(UniProtKB)
IEA
GO:0015035
P55789(UniProtKB)
IDA
GO:0016972
P55789(UniProtKB)
IEA
GO:0050660
P55789(UniProtKB)
IDA
GO:0055114
P55789(UniProtKB)
IEA

基因相互作用关系

基因相互作用关系

基因与其他基因之间的相互作用关系图
序号 作用方式 资源库来源/分值 基因名称 基因名称

基因相关microRNA

基因相关microRNA

可能调控GFER基因的相关microRNA：     

基因通路图

基因通路图

基因的通路属性图
通路基因列表

基因相关疾病

基因相关疾病

疾病名称 关系值 NofPmids NofSnps 来源
疾病名称 关系值 NofPmids NofSnps 来源
Myopathy, Mitochondrial Progressive, With Congenital Cataract, Hearing Loss, And Developmental Delay 0.480271442 1 1 BeFree_CLINVAR_CTD_human_ORPHANET_UNIPROT
Acute kidney injury 0.2 1 0 CTD_human_RGD
Liver Failure, Acute 0.120271442 2 0 BeFree_CTD_human
Toxic effect of carbon tetrachloride 0.12 1 0 CTD_human
Cryptorchidism 0.08 1 0 RGD
Ureteral obstruction 0.08 1 0 RGD
Sepsis 0.08 1 0 RGD
Endotoxemia 0.08 1 0 RGD
Drug-Induced Liver Injury 0.08 1 0 RGD
Liver Cirrhosis 0.003267234 2 0 BeFree_LHGDN
Liver regeneration disorder 0.001900093 7 0 BeFree
Liver carcinoma 0.001628651 6 0 BeFree
Diabetic Retinopathy 0.000814326 3 0 BeFree
Diabetes Mellitus 0.000542884 2 0 BeFree
Kidney Failure, Acute 0.000542884 2 0 BeFree
Liver diseases 0.000542884 2 0 BeFree
Liver neoplasms 0.000542884 2 0 BeFree
Myopathy 0.000542884 2 1 BeFree
Hepatocarcinogenesis 0.000542884 2 0 BeFree
Non-Neoplastic Disorder 0.000542884 2 0 BeFree
Nonproliferative diabetic retinopathy 0.000271442 1 0 BeFree
Malignant tumor of colon 0.000271442 1 0 BeFree
Colorectal Carcinoma 0.000271442 1 0 BeFree
Diabetes 0.000271442 1 0 BeFree
Diabetes Mellitus, Insulin-Dependent 0.000271442 1 0 BeFree
Glioma 0.000271442 1 0 BeFree
Sensorineural Hearing Loss (disorder) 0.000271442 1 0 BeFree
Hepatitis B 0.000271442 1 0 BeFree
Hepatitis C 0.000271442 1 0 BeFree
Ischemia 0.000271442 1 0 BeFree
Acute lymphocytic leukemia 0.000271442 1 0 BeFree
Peripheral Neuropathy 0.000271442 1 0 BeFree
Peritonitis 0.000271442 1 0 BeFree
Cataract 0.000271442 1 1 BeFree
Proliferative diabetic retinopathy 0.000271442 1 0 BeFree
Hearing Loss, Mixed Conductive-Sensorineural 0.000271442 1 1 BeFree
Cholangiocarcinoma 0.000271442 1 0 BeFree
Peritoneal Fibrosis 0.000271442 1 0 BeFree
Colon Carcinoma 0.000271442 1 0 BeFree
Mitochondrial Diseases 0.000271442 1 0 BeFree
Colorectal Cancer 0.000271442 1 0 BeFree
Cirrhosis 0.000271442 1 0 BeFree
Precursor Cell Lymphoblastic Leukemia Lymphoma 0.000271442 1 0 BeFree

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