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This gene belongs to the guanine-binding protein (GBP) family, which includes interferon-induced proteins that can bind to guanine nucleotides (GMP, GDP and GTP). The encoded protein is a GTPase which hydrolyzes GTP, predominantly to GDP. The protein may play a role as a marker of squamous cell carcinomas. [provided by RefSeq, Jul 2013]
[中文简述(自动翻译):]  该基因属于鸟嘌呤结合蛋白(GBP)系列,其中包括可结合鸟嘌呤核苷酸(GMP,GDP和GTP)干扰素诱导蛋白。编码的蛋白是GTP水解,主要是对GDP的GTP酶。蛋白质可以发挥作用如鳞状细胞癌的标记物。 [由RefSeq的,2013年7月提供]
GBP2基因(以及对应的蛋白质)的细胞分布位置:
GBP2基因的本体(GO)信息:
疾病名称 | 关系值 | NofPmids | NofSnps | 来源 |
Myocardial Ischemia | 0.12 | 1 | 0 | CTD_human |
Squamous cell carcinoma | 0.00272435 | 1 | 0 | LHGDN |
Hepatitis B | 0.002367032 | 1 | 0 | GAD |
Diminished ovarian reserve | 0.000271442 | 1 | 0 | BeFree |
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